Yue Si, Ph.D.
Affiliations: | 2005 | Indiana University, Bloomington, Bloomington, IN, United States |
Area:
Microbiology BiologyGoogle:
"Yue Si"Parents
Sign in to add mentorWade D. Clapp | grad student | 2005 | Indiana University Bloomington | |
(Use of a human foamy viral construct encoding recombinant FANCC to correct the hematopoietic stem cell defect and prevent the development of myeloid malignancies in Fancc-/- mice.) |
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Publications
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Pulliam-Leath AC, Ciccone SL, Nalepa G, et al. (2010) Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia. Blood. 116: 2915-20 |
Si Y, Pulliam AC, Linka Y, et al. (2008) Overnight transduction with foamyviral vectors restores the long-term repopulating activity of Fancc-/- stem cells. Blood. 112: 4458-65 |
Si Y, Ciccone S, Yang FC, et al. (2006) Continuous in vivo infusion of interferon-gamma (IFN-gamma) enhances engraftment of syngeneic wild-type cells in Fanca-/- and Fancg-/- mice. Blood. 108: 4283-7 |
Ciccone S, Pulliam A, Li X, et al. (2006) A Model of Clonal Evolution and Myelodysplasia (MDS) on Mice with Genetic Disruption of Both Fancc and Fancg. Blood. 108: 2627-2627 |
Si Y, Leurs C, Srour EF, et al. (2005) 470. Foamy Viral Mediated Transduction of Recombinant FANCC in the Absence of Prestimulation Is Sufficient To Restore the Long Term Repopulating Activity of Fancc -/- Stem Cells and Prevent the Acquisition of Myeloid Malignancies Molecular Therapy. 11 |
Si Y, Leurs C, Srour E, et al. (2004) Short-Term Foamyviral Transduction with Virions Encoding Recombinant Corrects the Mitomycin C Hypersensitivity of Fancc −/− Progenitor Cells In Vitro and Restores Long Term Repopulating Activity of Fancc −/− Stem Cells In Vivo. Blood. 104: 3171-3171 |