Carlos J. Orihuela, Ph.D.

2001 University of Texas Medical Branch, Galveston, TX 
Microbiology Biology, Molecular Biology
"Carlos Orihuela"


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David W. Niesel grad student 2001 UTMB
 (Characterization of Streptococcus pneumoniae gene expression in a novel murine peritoneal cavity model.)
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D'Mello A, Riegler AN, Martínez E, et al. (2020) An in vivo atlas of host-pathogen transcriptomes during colonization and disease. Proceedings of the National Academy of Sciences of the United States of America
Africano HF, Serrano-Mayorga CC, Ramirez-Valbuena PC, et al. (2020) Major Adverse Cardiovascular Events During Invasive Pneumococcal Disease are Serotype Dependent. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America
Beno SM, Riegler AN, Gilley RP, et al. (2020) Necroptosis inhibition prevents long-term cardiac damage during pneumococcal pneumonia and invasive disease. The Journal of Infectious Diseases
Hinojosa CA, Gonzalez-Juarbe N, Rahman MM, et al. (2020) Omega-3 fatty acids in contrast to omega-6 protect against pneumococcal pneumonia. Microbial Pathogenesis. 103979
Riegler AN, Brissac T, Gonzalez-Juarbe N, et al. (2019) Necroptotic Cell Death Promotes Adaptive Immunity Against Colonizing Pneumococci. Frontiers in Immunology. 10: 615
Loughran AJ, Orihuela CJ, Tuomanen EI. (2019) : Invasion and Inflammation. Microbiology Spectrum. 7
Pajuelo D, Gonzalez-Juarbe N, Tak U, et al. (2018) NAD Depletion Triggers Macrophage Necroptosis, a Cell Death Pathway Exploited by Mycobacterium tuberculosis. Cell Reports. 24: 429-440
Gonzalez-Juarbe N, Bradley KM, Riegler AN, et al. (2018) Bacterial Pore-Forming Toxins Promote the Activation of Caspases in Parallel to Necroptosis to Enhance Alarmin Release and Inflammation During Pneumonia. Scientific Reports. 8: 5846
Shenoy AT, Brissac T, Gilley RP, et al. (2017) Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing. Plos Pathogens. 13: e1006582
Mangat M, Amalakuhan B, Habib S, et al. (2017) High endocan levels are associated with the need for mechanical ventilation among patients with severe sepsis. The European Respiratory Journal. 50
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