Douglas F. Lake

University of Arizona, Tucson, AZ 
Immunology, Microbiology Biology, Medicine and Surgery
"Douglas Lake"
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Fifield AL, Hanavan PD, Faigel DO, et al. (2019) Molecular Inhibitor of QSOX1 Suppresses Tumor Growth in vivo. Molecular Cancer Therapeutics
Liu J, Hanavan PD, Kras K, et al. (2018) Loss of SETD2 induces a metabolic switch in renal cell carcinoma cell lines toward enhanced oxidative phosphorylation. Journal of Proteome Research
Tran L, Hanavan PD, Campbell LE, et al. (2016) Prolonged Exposure of Primary Human Muscle Cells to Plasma Fatty Acids Associated with Obese Phenotype Induces Persistent Suppression of Muscle Mitochondrial ATP Synthase β Subunit. Plos One. 11: e0160057
Faigel DO, Lake DF, Landreth TL, et al. (2016) EUS-guided portal injection chemotherapy for treatment of hepatic metastases: feasibility in the acute porcine model. Gastrointestinal Endoscopy. 83: 444-6
Tiedemann RL, Hlady RA, Hanavan PD, et al. (2015) Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma. Oncotarget
Hanavan PD, Borges CR, Katchman BA, et al. (2015) Ebselen inhibits QSOX1 enzymatic activity and suppresses invasion of pancreatic and renal cancer cell lines. Oncotarget. 6: 18418-28
Blair JE, Chang YH, Ruiz Y, et al. (2014) Distance from construction site and risk for coccidioidomycosis, Arizona, USA. Emerging Infectious Diseases. 20: 1464-71
Borges CR, Lake DF. (2014) Oxidative protein folding: nature's knotty challenge. Antioxidants & Redox Signaling. 21: 392-5
Lake DF, Faigel DO. (2014) The emerging role of QSOX1 in cancer. Antioxidants & Redox Signaling. 21: 485-96
Katchman BA, Ocal IT, Cunliffe HE, et al. (2013) Expression of quiescin sulfhydryl oxidase 1 is associated with a highly invasive phenotype and correlates with a poor prognosis in Luminal B breast cancer. Breast Cancer Research : Bcr. 15: R28
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