James E. Gomez, Ph.D.

Affiliations: 
Harvard University, Cambridge, MA, United States 
 2000 Johns Hopkins University, Baltimore, MD 
Area:
Microbiology Biology, Genetics, Molecular Biology
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"James Gomez"

Parents

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William R. Bishai grad student 2000 Johns Hopkins (Chemistry Tree)
 (Characterization of mycobacterail homologues of whiB, a Streptomyces coelicolor gene required for sporulation.)
John McKinney post-doc Rockefeller
Deborah T. Hung research scientist Harvard
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Publications

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Johnson EO, LaVerriere E, Office E, et al. (2019) Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes. Nature
Fang C, Lee KK, Nietupski R, et al. (2018) Discovery of heterocyclic replacements for the coumarin core of anti-tubercular FadD32 inhibitors. Bioorganic & Medicinal Chemistry Letters
Gomez JE, Kaufmann-Malaga BB, Wivagg CN, et al. (2017) Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug environment. Elife. 6
Wivagg CN, Wellington S, Gomez JE, et al. (2016) Loss of a Class A Penicillin-Binding Protein Alters β-Lactam Susceptibilities in Mycobacterium tuberculosis. Acs Infectious Diseases. 2: 104-10
Zhang D, Gomez JE, Chien JY, et al. (2016) Genomic analysis of the evolution of fluoroquinolone resistance in Mycobacterium tuberculosis prior to tuberculosis diagnosis. Antimicrobial Agents and Chemotherapy
Wivagg CN, Wellington S, Gomez JE, et al. (2016) Loss of a Class A Penicillin-Binding Protein Alters β-Lactam Susceptibilities in Mycobacterium tuberculosis Acs Infectious Diseases. 2: 104-110
Barczak AK, Gomez JE, Kaufmann BB, et al. (2012) RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities. Proceedings of the National Academy of Sciences of the United States of America. 109: 6217-22
Gomez JE, Clatworthy A, Hung DT. (2011) Probing bacterial pathogenesis with genetics, genomics, and chemical biology: past, present, and future approaches. Critical Reviews in Biochemistry and Molecular Biology. 46: 41-66
Muñoz-Elías EJ, Timm J, Botha T, et al. (2005) Replication dynamics of Mycobacterium tuberculosis in chronically infected mice. Infection and Immunity. 73: 546-51
Hisert KB, Kirksey MA, Gomez JE, et al. (2004) Identification of Mycobacterium tuberculosis counterimmune (cim) mutants in immunodeficient mice by differential screening. Infection and Immunity. 72: 5315-21
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