Sherry F. Queener
Affiliations: | Indiana University, Bloomington, Bloomington, IN, United States |
Area:
Pharmacology, Microbiology Biology, Molecular BiologyGoogle:
"Sherry Queener"Children
Sign in to add trainee| Jeniece M. Nott | grad student | 2000 | Indiana University |
| Dongjiu Ye | grad student | 2000 | Indiana University |
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Publications
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| Shah K, Queener S, Cody V, et al. (2019) Development of substituted pyrido[3,2-d]pyrimidines as potent and selective dihydrofolate reductase inhibitors for pneumocystis pneumonia infection. Bioorganic & Medicinal Chemistry Letters |
| Shah K, Lin X, Queener SF, et al. (2018) Targeting species specific amino acid residues: Design, synthesis and biological evaluation of 6-substituted pyrrolo[2,3-d]pyrimidines as dihydrofolate reductase inhibitors and potential anti-opportunistic infection agents. Bioorganic & Medicinal Chemistry |
| Gangjee A, Mavandadi F, Kisliuk RL, et al. (2016) 2-Amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines as Nonclassical Antifolate Inhibitors of Thymidylate Synthase. Journal of Medicinal Chemistry. 40: 632 |
| Zaware N, Sharma H, Yang J, et al. (2013) Discovery of potent and selective inhibitors of Toxoplasma gondii thymidylate synthase for opportunistic infections. Acs Medicinal Chemistry Letters. 4: 1148-1151 |
| Queener SF, Cody V, Pace J, et al. (2013) Trimethoprim resistance of dihydrofolate reductase variants from clinical isolates of Pneumocystis jirovecii. Antimicrobial Agents and Chemotherapy. 57: 4990-8 |
| Gangjee A, Namjoshi OA, Raghavan S, et al. (2013) Design, synthesis, and molecular modeling of novel pyrido[2,3-d]pyrimidine analogues as antifolates; application of Buchwald-Hartwig aminations of heterocycles. Journal of Medicinal Chemistry. 56: 4422-41 |
| Cody V, Pace J, Queener SF, et al. (2013) Kinetic and structural analysis for potent antifolate inhibition of Pneumocystis jirovecii, Pneumocystis carinii, and human dihydrofolate reductases and their active-site variants. Antimicrobial Agents and Chemotherapy. 57: 2669-77 |
| Konrad C, Queener SF, Wek RC, et al. (2013) Inhibitors of eIF2α dephosphorylation slow replication and stabilize latency in Toxoplasma gondii. Antimicrobial Agents and Chemotherapy. 57: 1815-22 |
| Cody V, Pace J, Piraino J, et al. (2011) Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase. Journal of Structural Biology. 176: 52-9 |
| Bag S, Tawari NR, Degani MS, et al. (2010) Design, synthesis, biological evaluation and computational investigation of novel inhibitors of dihydrofolate reductase of opportunistic pathogens. Bioorganic & Medicinal Chemistry. 18: 3187-97 |