Robert G. Korneluk
Affiliations: | University of Ottawa, Ottawa, ON, Canada |
Area:
Microbiology Biology, Molecular Biology, Cell BiologyGoogle:
"Robert Korneluk"
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Publications
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| Beug ST, Korneluk RG, LaCasse EC. (2019) Sp3-cificity of TNF-α expression promotes the Smac mimetic-mediated killing of cancer cells. Molecular & Cellular Oncology. 6: 1607456 |
| Lala-Tabbert N, Lejmi-Mrad R, Timusk K, et al. (2019) Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy. Skeletal Muscle. 9: 13 |
| Beug ST, Cheung HH, Sanda T, et al. (2019) The transcription factor SP3 drives TNF-α expression in response to Smac mimetics. Science Signaling. 12 |
| Beug ST, Pichette SJ, St-Jean M, et al. (2018) Combination of IAP Antagonists and TNF-α-Armed Oncolytic Viruses Induce Tumor Vascular Shutdown and Tumor Regression. Molecular Therapy Oncolytics. 10: 28-39 |
| Rijal D, Ariana A, Wight A, et al. (2018) Differentiated Macrophages Acquire a Pro-Inflammatory and Cell Death-Resistant Phenotype Due to Increasing XIAP and P38-mediated inhibition of RipK1. The Journal of Biological Chemistry |
| Alturki NA, McComb S, Ariana A, et al. (2018) Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis. Cell Death & Disease. 9: 592 |
| Beug ST, Beauregard CE, Healy C, et al. (2017) Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma. Nature Communications. 8 |
| Dobson CC, Naing T, Beug ST, et al. (2016) Oncolytic virus synergizes with Smac mimetic compounds to induce rhabdomyosarcoma cell death in a syngeneic murine model. Oncotarget |
| LaCasse E, Beug S, Healey C, et al. (2016) Abstract B034: Smac mimetics synergistically improve the efficacy of cancer immunotherapies including immune checkpoint blockade in preclinical models Cancer Immunology Research. 4 |
| Beug ST, Conrad DP, Alain T, et al. (2015) Combinatorial cancer immunotherapy strategies with proapoptotic small-molecule IAP antagonists. The International Journal of Developmental Biology. 59: 141-7 |