Edmund C. Kim, Ph.D.

Affiliations: 
2003 Weill Cornell Medical College, New York, NY, United States 
Area:
Immunology, Molecular Biology
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"Edmund Kim"

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Paolo Casali grad student 2003 Weill Cornell Medical College
 (Regulation of immunoglobulin heavy chain gene expression in human B cells: A dual function of activation and inhibition by HOXC4 and octamer homeodomain proteins.)
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Publications

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Kim EC, Edmonston CR, Wu X, et al. (2004) The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch DNA recombination. The Journal of Biological Chemistry. 279: 42258-69
Wu X, Feng J, Komori A, et al. (2003) Immunoglobulin somatic hypermutation: double-strand DNA breaks, AID and error-prone DNA repair. Journal of Clinical Immunology. 23: 235-46
Schaffer A, Kim EC, Wu X, et al. (2003) Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements. The Journal of Biological Chemistry. 278: 23141-50
Cerutti A, Zan H, Kim EC, et al. (2002) Ongoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells. Journal of Immunology (Baltimore, Md. : 1950). 169: 6594-603
Cerutti A, Kim EC, Shah S, et al. (2001) Dysregulation of CD30+ T cells by leukemia impairs isotype switching in normal B cells. Nature Immunology. 2: 150-6
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