Paul Spearman

Vanderbilt University, Nashville, TN 
Microbiology Biology, Cell Biology
"Paul Spearman"
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Singh K, Marasini B, Chen X, et al. (2020) A bivalent, spherical virus-like particle vaccine enhances breadth of immune responses against pathogenic Ebola viruses in rhesus macaques. Journal of Virology
Buffone C, Kutzner J, Opp S, et al. (2019) The ability of SAMHD1 to block HIV-1 but not SIV requires expression of MxB. Virology. 531: 260-268
Rampoldi A, Crooke SN, Preininger MK, et al. (2018) Targeted Elimination of Tumorigenic Human Pluripotent Stem Cells Using Suicide-inducing Virus-like Particles. Acs Chemical Biology
Kirschman J, Qi M, Ding L, et al. (2017) HIV-1 Envelope Glycoprotein Trafficking through the Endosomal Recycling Compartment is Required for Particle Incorporation. Journal of Virology
Staitieh BS, Ding L, Neveu WA, et al. (2017) HIV-1 decreases Nrf2/ARE activity and phagocytic function in alveolar macrophages. Journal of Leukocyte Biology
Hammonds JE, Beeman N, Ding L, et al. (2017) Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1. Plos Pathogens. 13: e1006181
Hampton CM, Strauss JD, Ke Z, et al. (2017) Correlated fluorescence microscopy and cryo-electron tomography of virus-infected or transfected mammalian cells. Nature Protocols. 12: 150-167
St Gelais C, Kim SH, Ding L, et al. (2016) A Putative Cyclin-binding Motif in Human SAMHD1 Contributes to Protein Phosphorylation, Localization and Stability. The Journal of Biological Chemistry
Spearman P. (2016) HIV-1 Gag as an Antiviral Target: Development of Assembly and Maturation Inhibitors. Current Topics in Medicinal Chemistry. 16: 1154-66
Strauss JD, Hammonds JE, Yi H, et al. (2015) Three-Dimensional Structural Characterization of HIV-1 Tethered to Human Cells. Journal of Virology
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