Kim Bottomly

1980-2007 Yale University, New Haven, CT 
 2007- President Wellesley College, Wellesley, MA, United States 
Cell Biology, Microbiology Biology, Molecular Biology
"Kim Bottomly"


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M. Roy Schwarz grad student 1975 University of Washington (Cell Biology Tree)
 (Differences in populations of lymphocytes in tolerant and nontolerant rats as determined by antibody labeling and 3H-uridine uptake.)
William Erwin Paul post-doc 1980 National Institute of Health (Cell Biology Tree)


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Patricia J. Jorritsma grad student 2002 Yale
Charlotte E. Ariyan grad student 2003 Yale
Frances B. Balamuth grad student 2003 Yale
Stephanie C. Colegio-Eisenbarth grad student 2003 Yale
Sarah Nikiforow grad student 2004 Yale
Damani A. Piggott grad student 2004 Yale
Rachael P. Jackman grad student 2007 Yale
Anna M. Tan grad student 2008 Yale
Simon Carding post-doc Yale (Cell Biology Tree)
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Janeway CA, Bottomly K, Babich J, et al. (2014) Quantitative variation in la antigen expression plays a central role in immune regulation. Immunology Today. 5: 99-105
Czyzyk J, Henegariu O, Preston-Hurlburt P, et al. (2012) Enhanced anti-serpin antibody activity inhibits autoimmune inflammation in type 1 diabetes. Journal of Immunology (Baltimore, Md. : 1950). 188: 6319-27
Dokmeci E, Xu L, Robinson E, et al. (2011) EBI3 deficiency leads to diminished T helper type 1 and increased T helper type 2 mediated airway inflammation. Immunology. 132: 559-66
Chapoval SP, Lee CG, Tang C, et al. (2009) Lung vascular endothelial growth factor expression induces local myeloid dendritic cell activation. Clinical Immunology (Orlando, Fla.). 132: 371-84
Czyzyk J, Chen HC, Bottomly K, et al. (2008) p21 Ras/impedes mitogenic signal propagation regulates cytokine production and migration in CD4 T cells. The Journal of Biological Chemistry. 283: 23004-15
DOKMECI E, XU L, BOTTOMLY K. (2008) EBI3 Deficient Cells Can Produce Comparable Levels of INF-g in the Presence of IL12 Journal of Allergy and Clinical Immunology. 121: S17-S17
Holt JP, Bottomly K, Mooseker MS. (2007) Assessment of myosin II, Va, VI and VIIa loss of function on endocytosis and endocytic vesicle motility in bone marrow-derived dendritic cells. Cell Motility and the Cytoskeleton. 64: 756-66
Jackman RP, Balamuth F, Bottomly K. (2007) CTLA-4 differentially regulates the immunological synapse in CD4 T cell subsets. Journal of Immunology (Baltimore, Md. : 1950). 178: 5543-51
Chen H, Piggott D, Xu L, et al. (2007) CD4+CD25+ T cells Regulate TLR4 Signaling in Pulmonary Dendritic Cells Journal of Allergy and Clinical Immunology. 119: S308
Dokmeci E, Xu L, Blumberg R, et al. (2007) EBI3 Deficient Naive T cells Show Increase in Expression of Th2 Mediated Cytokines In-vitro Journal of Allergy and Clinical Immunology. 119: S45
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