Steven Z. Josefowicz, Ph.D.

2010 University of Washington, Seattle, Seattle, WA 
"Steven Josefowicz"


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Alexander Y. Rudensky grad student 2010 University of Washington
 (Control of Foxp3 expression and regulatory T cell fate.)
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Samstein RM, Arvey A, Josefowicz SZ, et al. (2012) Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification. Cell. 151: 153-66
Samstein RM, Josefowicz SZ, Arvey A, et al. (2012) Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict. Cell. 150: 29-38
Josefowicz SZ, Niec RE, Kim HY, et al. (2012) Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature. 482: 395-9
Josefowicz SZ, Lu LF, Rudensky AY. (2012) Regulatory T cells: mechanisms of differentiation and function. Annual Review of Immunology. 30: 531-64
Rubtsov YP, Niec RE, Josefowicz S, et al. (2010) Stability of the regulatory T cell lineage in vivo. Science (New York, N.Y.). 329: 1667-71
Zheng Y, Josefowicz S, Chaudhry A, et al. (2010) Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature. 463: 808-12
Nakamura S, Otani T, Tsuji-Takayama K, et al. (2010) Regulatory T cells (PP-045) International Immunology. 22
Josefowicz SZ, Wilson CB, Rudensky AY. (2009) Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1. Journal of Immunology (Baltimore, Md. : 1950). 182: 6648-52
Zheng Y, Josefowicz SZ, Kas A, et al. (2007) Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature. 445: 936-40
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