Xiaoyun Wen, Ph.D.

2010 Albany Medical College of Union University 
Virology Biology, Microbiology Biology, Molecular Biology
"Xiaoyun Wen"


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Carlos M. de Noronha grad student 2010 Albany Medical College of Union University
 (HIV1 VPR function is mediated through interaction with the DD 1•CUL4 ubiquitin ligase complex.)
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Qi M, Chu H, Chen X, et al. (2015) A tyrosine-based motif in the HIV-1 envelope glycoprotein tail mediates cell-type- and Rab11-FIP1C-dependent incorporation into virions. Proceedings of the National Academy of Sciences of the United States of America. 112: 7575-80
Wen X, Ding L, Hunter E, et al. (2014) An siRNA screen of membrane trafficking genes highlights pathways common to HIV-1 and M-PMV virus assembly and release. Plos One. 9: e106151
Wen X, Ding L, Wang JJ, et al. (2014) ROCK1 and LIM kinase modulate retrovirus particle release and cell-cell transmission events. Journal of Virology. 88: 6906-21
Pereira LE, Clark J, Grznarova P, et al. (2014) Direct evidence for intracellular anterograde co-transport of M-PMV Gag and Env on microtubules. Virology. 449: 109-19
Casey Klockow L, Sharifi HJ, Wen X, et al. (2013) The HIV-1 protein Vpr targets the endoribonuclease Dicer for proteasomal degradation to boost macrophage infection. Virology. 444: 191-202
Qi M, Williams JA, Chu H, et al. (2013) Rab11-FIP1C and Rab14 direct plasma membrane sorting and particle incorporation of the HIV-1 envelope glycoprotein complex. Plos Pathogens. 9: e1003278
Chu H, Wang JJ, Qi M, et al. (2012) Tetherin/BST-2 is essential for the formation of the intracellular virus-containing compartment in HIV-infected macrophages. Cell Host & Microbe. 12: 360-72
Chu H, Wang JJ, Qi M, et al. (2012) The intracellular virus-containing compartments in primary human macrophages are largely inaccessible to antibodies and small molecules. Plos One. 7: e35297
Wen X, Casey Klockow L, Nekorchuk M, et al. (2012) The HIV1 protein Vpr acts to enhance constitutive DCAF1-dependent UNG2 turnover. Plos One. 7: e30939
Casey L, Wen X, de Noronha CM. (2010) The functions of the HIV1 protein Vpr and its action through the DCAF1.DDB1.Cullin4 ubiquitin ligase. Cytokine. 51: 1-9
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