Richard M. Locksley

Affiliations: 
Biomedical Sciences University of California, San Francisco, San Francisco, CA 
Area:
Immunology, Microbiology Biology, Cell Biology
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"Richard Locksley"

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Steven L. Reiner grad student (Cell Biology Tree)
Husein Hadeiba grad student 2002 UCSF
Kanade Shinkai grad student 2002 UCSF
Daniel B. Stetson grad student 2002 UCSF
Davina Wu grad student 2010 UCSF
Alexander Mohapatra grad student 2014 UCSF
Jakob Helmuth von Moltke post-doc UCSF (ID Tree)
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Publications

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O'Keefe RN, Carli ALE, Baloyan D, et al. (2023) A tuft cell - ILC2 signaling circuit provides therapeutic targets to inhibit gastric metaplasia and tumor development. Nature Communications. 14: 6872
Sbierski-Kind J, Cautivo KM, Wagner JC, et al. (2023) Group 2 innate lymphoid cells constrain type 3/17 lymphocytes in shared stromal niches to restrict liver fibrosis. Biorxiv : the Preprint Server For Biology
Molofsky AB, Locksley RM. (2023) The ins and outs of innate and adaptive type 2 immunity. Immunity. 56: 704-722
Ricardo-Gonzalez RR, Kotas ME, O'Leary CE, et al. (2022) Innate type 2 immunity controls hair follicle commensalism by Demodex mites. Immunity
Kotas ME, Moore CM, Gurrola Ii JG, et al. (2022) IL-13-programmed airway tuft cells produce PGE2, which promotes CFTR-dependent mucociliary function. Jci Insight
O'Leary CE, Sbierski-Kind J, Kotas ME, et al. (2022) Bile acid-sensitive tuft cells regulate biliary neutrophil influx. Science Immunology. 7: eabj1080
Cautivo KM, Matatia PR, Lizama CO, et al. (2022) Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation. Immunity. 55: 254-271.e7
Kotas ME, Mroz NM, Koga S, et al. (2021) CISH constrains the tuft-ILC2 circuit to set epithelial and immune tone. Mucosal Immunology
Kotas ME, Dion J, Van Dyken S, et al. (2021) A role for IL-33-activated ILC2s in eosinophilic vasculitis. Jci Insight
Kastenschmidt JM, Coulis G, Farahat PK, et al. (2021) A stromal progenitor and ILC2 niche promotes muscle eosinophilia and fibrosis-associated gene expression. Cell Reports. 35: 108997
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