Reza Zarnegar

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Systematic Biology, Microbiology Biology, Cell Biology
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"Reza Zarnegar"
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Publications

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Seneviratne D, Ma J, Tan X, et al. (2015) Genomic instability causes HGF gene activation in colon cancer cells, promoting their resistance to necroptosis. Gastroenterology. 148: 181-191.e17
Ma J, Zou C, Guo L, et al. (2014) Novel Death Defying Domain in Met entraps the active site of caspase-3 and blocks apoptosis in hepatocytes. Hepatology (Baltimore, Md.). 59: 2010-21
Dai JY, DeFrances MC, Zou C, et al. (2009) The Met protooncogene is a transcriptional target of NF kappaB: implications for cell survival. Journal of Cellular Biochemistry. 107: 1222-36
Ma J, DeFrances MC, Zou C, et al. (2009) Somatic mutation and functional polymorphism of a novel regulatory element in the HGF gene promoter causes its aberrant expression in human breast cancer Journal of Clinical Investigation. 119: 478-491
Zou C, Ma J, Wang X, et al. (2007) Lack of Fas antagonism by Met in human fatty liver disease. Nature Medicine. 13: 1078-85
Zhao Y, Difrancesca D, Wang X, et al. (2007) Promotion of Fas-mediated apoptosis in Type II cells by high doses of hepatocyte growth factor bypasses the mitochondrial requirement. Journal of Cellular Physiology. 213: 556-63
Wang X, Zhou Y, Kim HP, et al. (2004) Hepatocyte growth factor protects against hypoxia/reoxygenation-induced apoptosis in endothelial cells. The Journal of Biological Chemistry. 279: 5237-43
Mehdi H, Manzi S, Desai P, et al. (2003) A functional polymorphism at the transcriptional initiation site in beta2-glycoprotein I (apolipoprotein H) associated with reduced gene expression and lower plasma levels of beta2-glycoprotein I. European Journal of Biochemistry / Febs. 270: 230-8
Wang X, DeFrances MC, Dai Y, et al. (2002) A mechanism of cell survival: sequestration of Fas by the HGF receptor Met. Molecular Cell. 9: 411-21
Jiang J, Johnson C, Zarnegar R. (2001) Peroxisome proliferator-activated receptor gamma-mediated transcriptional up-regulation of the hepatocyte growth factor gene promoter via a novel composite cis-acting element. Journal of Biological Chemistry. 276: 25049-25056
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