Simon-Pierre Gravel, Ph.D.

Affiliations: 
2010 Université de Montréal, Montréal, Canada 
Area:
Molecular Biology
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"Simon-Pierre Gravel"

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Marc Servant grad student 2010 Université de Montréal
 (Roles des kinases IKK et IKK-related dans les maladies inflammatoires chroniques; implications dans l'atherosclerose et la reponse hypoxique.)
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Publications

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Mellal K, Omri S, Mulumba M, et al. (2019) Immunometabolic modulation of retinal inflammation by CD36 ligand. Scientific Reports. 9: 12903
Hulea L, Gravel SP, Morita M, et al. (2018) Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides. Cell Metabolism
Shamalnasab M, Gravel SP, St-Pierre J, et al. (2018) A salicylic acid derivative extends the lifespan of Caenorhabditis elegans by activating autophagy and the mitochondrial unfolded protein response. Aging Cell. e12830
Im YK, Najyb O, Gravel SP, et al. (2018) Interplay between ShcA signaling and PGC-1α triggers targetable metabolic vulnerabilities in breast cancer. Cancer Research
Gravel SP. (2018) Deciphering the Dichotomous Effects of PGC-1α on Tumorigenesis and Metastasis. Frontiers in Oncology. 8: 75
Houles T, Gravel SP, Lavoie G, et al. (2018) RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma. Cancer Research
Rabinovitch RC, Samborska B, Faubert B, et al. (2017) AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species. Cell Reports. 21: 1-9
Hulea L, Cargnello M, Gravel S, et al. (2017) Abstract A31: eIF4F links translation to energy stress response in cancer Cancer Research. 77
Deblois G, Smith HW, Tam IS, et al. (2016) ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer. Nature Communications. 7: 12156
Audet-Walsh É, Papadopoli DJ, Gravel SP, et al. (2016) The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer. Cell Reports
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