Joseph Horwitz
Affiliations: | University of California, Los Angeles, Los Angeles, CA |
Area:
Molecular Biology, Cell BiologyWebsite:
https://people.healthsciences.ucla.edu/institution/personnel?personnel_id=45308Google:
"Joseph Horwitz"Bio:
https://iovs.arvojournals.org/article.aspx?articleid=2179266
Parents
Sign in to add mentor| E Hardin Strickland | grad student | 1970 | UCLA (Physiology Academic Tree) | |
| (Near Ultraviolet Circular Dichroism and Absorption Spectra of Phenylalanine , Tyrosine , and Ribonuclease - A at 298 and 77°K) | ||||
Children
Sign in to add trainee| Dana A. Haley | grad student | 2000 | UCLA |
| Yi-Wen Hsieh | grad student | 2007 | UCLA |
| Margaret McFall-Ngai | post-doc | 1984-1986 | UCLA (Microtree) |
BETA: Related publications
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Publications
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| Warmack RA, Shawa H, Liu K, et al. (2019) The L-isoaspartate modification within protein fragments in the aging lens can promote protein aggregation. The Journal of Biological Chemistry |
| Gangalum RK, Horwitz J, Kohan SA, et al. (2012) αA-crystallin and αB-crystallin reside in separate subcellular compartments in the developing ocular lens. The Journal of Biological Chemistry. 287: 42407-16 |
| Cheng C, Xia CH, Huang Q, et al. (2010) Altered chaperone-like activity of alpha-crystallins promotes cataractogenesis. The Journal of Biological Chemistry. 285: 41187-93 |
| Benesch JL, Aquilina JA, Baldwin AJ, et al. (2010) The quaternary organization and dynamics of the molecular chaperone HSP26 are thermally regulated. Chemistry & Biology. 17: 1008-17 |
| Laganowsky A, Benesch JL, Landau M, et al. (2010) Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Science : a Publication of the Protein Society. 19: 1031-43 |
| Huang Q, Ding L, Phan KB, et al. (2009) Mechanism of cataract formation in alphaA-crystallin Y118D mutation. Investigative Ophthalmology & Visual Science. 50: 2919-26 |
| Horwitz J. (2009) Alpha crystallin: the quest for a homogeneous quaternary structure. Experimental Eye Research. 88: 190-4 |
| Zhang X, Dudek EJ, Liu B, et al. (2007) Degradation of C-terminal truncated alpha A-crystallins by the ubiquitin-proteasome pathway. Investigative Ophthalmology & Visual Science. 48: 4200-8 |
| Wang K, Cheng C, Li L, et al. (2007) GammaD-crystallin associated protein aggregation and lens fiber cell denucleation. Investigative Ophthalmology & Visual Science. 48: 3719-28 |
| Ecroyd H, Meehan S, Horwitz J, et al. (2007) Mimicking phosphorylation of alphaB-crystallin affects its chaperone activity. The Biochemical Journal. 401: 129-41 |