Gökhan Tolun, M.S., Ph.D.

2000-2007 Biochemistry and Molecular Biology University of Miami Miller School of Medicine, Miami, FL, United States 
 2008-2012 Lineberger Comprehensive Cancer Center University of North Carlina at Chapel Hill 
 2012-2015 National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institutes of Health, Bethesda, MD, United States 
 2015-2017 National Cancer Institute, Frederick National Institutes of Health, Bethesda, MD, United States 
 2017- School of Chemistry and Molecular Bioscience University of Wollongong, Australia 
Structural Biology, Biochemistry, Molecular Imaging, Molecular Biology
"Gökhan Tolun"


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Richard S. Myers grad student 2007 University of Miami
 (More than the sum of its parts: Physical and mechanistic coupling in the phage lambda Red recombinase.)
Donald L. Court post-doc (Chemistry Tree)
Jack D. Griffith post-doc (Chemistry Tree)
Alasdair C. Steven post-doc (Chemistry Tree)


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Nicholas E. Dixon collaborator University of Wollongong, Australia (Chemistry Tree)
Peter J. Lewis collaborator
Steve Ludtke collaborator (StructuralBiologyTree)
Aaron J. Oakley collaborator University of Wollongong, Australia
Antoine M. van Oijen collaborator University of Wollongong, Australia (Chemistry Tree)
Haibo Yu collaborator (Chemistry Tree)
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Newing TP, Brewster JL, Fitschen LJ, et al. (2022) Redβ annealase structure reveals details of oligomerization and λ Red-mediated homologous DNA recombination. Nature Communications. 13: 5649
Newing TP, Oakley AJ, Miller M, et al. (2020) Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD. Nature Communications. 11: 6420
Brewster JL, Tolun G. (2020) Half a century of bacteriophage lambda recombinase: In vitro studies of lambda exonuclease and Red-beta annealase. Iubmb Life. 72: 1622-1633
Tolun G, Vijayasarathy C, Huang R, et al. (2016) Paired octamer rings of retinoschisin suggest a junctional model for cell-cell adhesion in the retina. Proceedings of the National Academy of Sciences of the United States of America
Tolun G, Vijayasarathy C, Huang R, et al. (2016) Retinoschisin at 4 Å Resolution from cryo-EM: A Junctional Model of Back-to-Back Octamers for Adhesion in the Retina Biophysical Journal. 110: 348a
Hickman AB, Ewis HE, Li X, et al. (2014) Structural basis of hAT transposon end recognition by Hermes, an octameric DNA transposase from Musca domestica. Cell. 158: 353-367
Tolun G, Makhov AM, Ludtke SJ, et al. (2013) Details of ssDNA annealing revealed by an HSV-1 ICP8-ssDNA binary complex. Nucleic Acids Research. 41: 5927-37
Tolun G, Cheng N, Heymann B, et al. (2013) Nucleic Acid Content of HBV Capsids Depends on its CTD-Phosphorylation State Microscopy and Microanalysis. 19: 54-55
Guo X, Kesimer M, Tolun G, et al. (2012) The NAD(+)-dependent protein deacetylase activity of SIRT1 is regulated by its oligomeric status. Scientific Reports. 2: 640
Tanner NA, Tolun G, Loparo JJ, et al. (2011) E. coli DNA replication in the absence of free β clamps. The Embo Journal. 30: 1830-40
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