Mohamed S. Abdel-Hakeem, Ph.D.
Affiliations: | 2007-2014 | Microbiology and Immunology | Université de Montréal, Montréal, Canada |
| 2014-2015 | Medical Microbiology and Immunology, Li Ka Shing Insitute of Virology | University of Alberta, Edmonton, Alberta, Canada | |
| 2015- | Microbiology and Immunology | Cairo University, Cairo, Giza Governorate, Egypt | |
| 2015-2021 | Microbiology, Institute for Immunology (IFI) | University of Pennsylvania, Philadelphia, PA, United States | |
| 2021- | Pathology & Laboratory Medicine | Emory University, Atlanta, GA |
Area:
"Adaptive immunity, T cell biology, T cell exhaustion, Viral infection, Cancer, Immunotherpay"Website:
https://med.emory.edu/departments/pathology/profile/?u=MABDE23Google:
"Mohamed S. Abdel-Hakeem"Parents
Sign in to add mentor| Naglaa Shoukry Mohamed | grad student | 2007-2014 | Université de Montréal |
| Michael Houghton | post-doc | 2014-2015 | |
| E John Wherry | post-doc | 2015-2021 | Penn (Cell Biology Tree) |
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Publications
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| Beltra JC, Manne S, Abdel-Hakeem MS, et al. (2020) Developmental Relationships of Four Exhausted CD8 T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms. Immunity |
| Kotzin JJ, Iseka F, Wright J, et al. (2019) The long noncoding RNA regulates CD8 T cells in response to viral infection. Proceedings of the National Academy of Sciences of the United States of America |
| Abdel-Hakeem MS. (2019) Viruses Teaching Immunology: Role of LCMV Model and Human Viral Infections in Immunological Discoveries. Viruses. 11: 106 |
| McLane LM, Abdel-Hakeem MS, Wherry EJ. (2019) CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer. Annual Review of Immunology |
| Abdel-Hakeem MS, Beltra J, Chen Z, et al. (2019) Abstract A166: Reprogramming of exhausted T-cells following cure of chronic viral infection Cancer Immunology Research. 7 |
| Sarhan MA, Abdel-Hakeem MS, Mason AL, et al. (2017) Glycogen synthase kinase 3β inhibitors prevent hepatitis C virus release/assembly through perturbation of lipid metabolism. Scientific Reports. 7: 2495 |
| Abdel-Hakeem MS, Boisvert M, Bruneau J, et al. (2017) Selective expansion of high functional avidity memory CD8 T cell clonotypes during hepatitis C virus reinfection and clearance. Plos Pathogens. 13: e1006191 |
| Zhang Y, El-Far M, Dupuy FP, et al. (2016) HCV RNA Activates APCs via TLR7/TLR8 While Virus Selectively Stimulates Macrophages Without Inducing Antiviral Responses. Scientific Reports. 6: 29447 |
| Abdel-Hakeem MS, Bédard N, Murphy D, et al. (2014) Signatures of protective memory immune responses during hepatitis C virus reinfection. Gastroenterology. 147: 870-881.e8 |
| Abdel-Hakeem MS, Shoukry NH. (2014) Protective immunity against hepatitis C: many shades of gray. Frontiers in Immunology. 5: 274 |