Grischa Chen

Affiliations: 
2012-2017 Medical Microbiology and Immunology University of Wisconsin, Madison, Madison, WI 
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"Grischa Chen"

Parents

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John-Demian Sauer grad student 2012-2017 UW Madison
 (Performed a screen to identify Listeria determinants of cytosolic survival and characterized the role of DHNA in this process)
Janelle S. Ayres post-doc 2017- Salk Institute (FlyTree)
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Publications

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Chen GY, Thorup NR, Miller AJ, et al. (2023) Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen. Science Advances. 9: eadg8719
Chen GY, Thorup NR, Miller AJ, et al. (2023) Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen. Biorxiv : the Preprint Server For Biology
Smith HB, Li TL, Liao MK, et al. (2021) MenI encodes a DHNA-CoA thioesterase necessary for menaquinone biosynthesis, cytosolic survival, and virulence. Infection and Immunity
Chen GY, Ayres JS. (2020) Beyond tug-of-war: Iron metabolism in cooperative host-microbe interactions. Plos Pathogens. 16: e1008698
McCarville JL, Chen GY, Cuevas VD, et al. (2020) Microbiota Metabolites in Health and Disease. Annual Review of Immunology. 38: 147-170
Schurig-Briccio LA, Parraga Solorzano PK, Lencina AM, et al. (2020) Role of respiratory NADH oxidation in the regulation of Staphylococcus aureus virulence. Embo Reports. e45832
Chen GY, Kao CY, Smith HB, et al. (2019) Mutation of the transcriptional regulator YtoI rescues mutants deficient in the essential shared metabolite 1,4-dihydroxy-2-naphthoate (DHNA). Infection and Immunity
Sanchez KK, Chen GY, Schieber AMP, et al. (2018) Cooperative Metabolic Adaptations in the Host Can Favor Asymptomatic Infection and Select for Attenuated Virulence in an Enteric Pathogen. Cell
Chen GY, Ayres JS. (2018) When the Gut Gets Tough, the Enterocytes Get Going. Immunity. 48: 837-839
Chen GY, Pensinger DA, Sauer JD. (2017) Listeria monocytogenes cytosolic metabolism promotes replication, survival and evasion of innate immunity. Cellular Microbiology
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