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David Frederick Stern

1988- Pathology Yale University, New Haven, CT 
Receptors and Signal Transduction
"David Frederick Stern"


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John J. Holland grad student 1983 UCSD
 (Multiplication of the avian coronavirus infectious bronchitis virus.)
Bartholomew M. Sefton grad student 1983 UCSD (Cell Biology Tree)
Robert A. Weinberg post-doc 1983 Whitehead Institute for Biomedical Research (Chemistry Tree)


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Pan Zheng grad student Yale
David S. Fay grad student 1995 Yale (Cell Biology Tree)
Dhara N. Amin grad student 2003 Yale
Nianhan J. Ma grad student 2008 Yale
Jerrica L. Breindel grad student 2012 Yale
Kathryn A. Tworkoski grad student 2013 Yale
David J. Riese post-doc 1993-1997 Yale (Chemistry Tree)
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Gale M, Li Y, Cao J, et al. (2019) Acquired resistance to HER2-targeted therapies creates vulnerability to ATP synthase inhibition. Cancer Research
Colavito SA, Platt JT, Held MA, et al. (2019) Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer. Oncotarget. 10: 4822-4839
Theodosakis N, Langdon CG, Micevic G, et al. (2018) Inhibition of isoprenylation synergizes with MAPK blockade to prevent growth in treatment-resistant melanoma, colorectal, and lung cancer. Pigment Cell & Melanoma Research
Stern DF. (2018) Keeping Tumors Out of the MAPK Fitness Zone. Cancer Discovery. 8: 20-23
Klein MI, Stern DF, Zhao H. (2017) GRAPE: a pathway template method to characterize tissue-specific functionality from gene expression profiles. Bmc Bioinformatics. 18: 317
Theodosakis N, Micevic G, Langdon CG, et al. (2017) p90RSK blockade inhibits dual BRAF and MEK inhibitor-resistant melanoma by targeting protein synthesis. The Journal of Investigative Dermatology
Langdon CG, Platt JT, Means RE, et al. (2017) Combinatorial screening of pancreatic adenocarcinoma reveals sensitivity to drug combinations including bromodomain inhibitor plus neddylation inhibitor. Molecular Cancer Therapeutics
Wali VB, Langdon CG, Held MA, et al. (2016) Systematic drug screening identifies tractable targeted combination therapies in triple-negative breast cancer. Cancer Research
Jeong J, VanHouten JN, Dann P, et al. (2016) PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer. Proceedings of the National Academy of Sciences of the United States of America
Haskins JW, Zhang S, Means RE, et al. (2015) Neuregulin-activated ERBB4 induces the SREBP-2 cholesterol biosynthetic pathway and increases low-density lipoprotein uptake. Science Signaling. 8: ra111
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