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David Frederick Stern

1988- Pathology Yale University, New Haven, CT 
Receptors and Signal Transduction
"David Frederick Stern"


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John J. Holland grad student 1983 UCSD
 (Multiplication of the avian coronavirus infectious bronchitis virus.)
Bartholomew M. Sefton grad student 1983 UCSD (Cell Biology Tree)
Robert A. Weinberg post-doc 1983 Whitehead Institute for Biomedical Research (Chemistry Tree)


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Pan Zheng grad student Yale
David S. Fay grad student 1995 Yale (Cell Biology Tree)
Dhara N. Amin grad student 2003 Yale
Nianhan J. Ma grad student 2008 Yale
Jerrica L. Breindel grad student 2012 Yale
Kathryn A. Tworkoski grad student 2013 Yale
David J. Riese post-doc 1993-1997 Yale (Chemistry Tree)
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Haskins JW, Zhang S, Means RE, et al. (2015) Neuregulin-activated ERBB4 induces the SREBP-2 cholesterol biosynthetic pathway and increases low-density lipoprotein uptake. Science Signaling. 8: ra111
Langdon CG, Wiedemann N, Held MA, et al. (2015) SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells. Oncotarget
Theodosakis N, Held MA, Marzuka-Alcala A, et al. (2015) BRAF Inhibition Decreases Cellular Glucose Uptake in Melanoma in Association with Reduction in Cell Volume. Molecular Cancer Therapeutics. 14: 1680-92
Langdon CG, Held MA, Platt JT, et al. (2015) The broad-spectrum receptor tyrosine kinase inhibitor dovitinib suppresses growth of BRAF-mutant melanoma cells in combination with other signaling pathway inhibitors. Pigment Cell & Melanoma Research. 28: 417-30
Scortegagna M, Lau E, Zhang T, et al. (2015) PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets. Cancer Research. 75: 1399-412
Wali VB, Gilmore-Hebert M, Mamillapalli R, et al. (2014) Overexpression of ERBB4 JM-a CYT-1 and CYT-2 isoforms in transgenic mice reveals isoform-specific roles in mammary gland development and carcinogenesis. Breast Cancer Research : Bcr. 16: 501
Haskins JW, Nguyen DX, Stern DF. (2014) Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration. Science Signaling. 7: ra116
Colavito SA, Zou MR, Yan Q, et al. (2014) Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway. Breast Cancer Research : Bcr. 16: 444
Bai Y, Cheng H, Bordeaux J, et al. (2013) Comparison of HER2 and phospho-HER2 expression between biopsy and resected breast cancer specimens using a quantitative assessment method. Plos One. 8: e79901
Breindel JL, Haskins JW, Cowell EP, et al. (2013) EGF receptor activates MET through MAPK to enhance non-small cell lung carcinoma invasion and brain metastasis. Cancer Research. 73: 5053-65
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