Janet A. Houghton
Affiliations: | Cancer Biology | Cleveland Clinic Lerner Research Institute |
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"Janet Houghton"Children
Sign in to add trainee| research assistant | 2010-2011 | Cleveland Clinic Lerner Research Institute |
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| Zhang R, Wu J, Ferrandon S, et al. (2016) Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing. Oncotarget |
| Agyeman A, Jha BK, Mazumdar T, et al. (2014) Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding. Oncotarget. 5: 4492-503 |
| Agyeman A, Jha BK, Mazumder T, et al. (2014) Abstract 1759: Targeting GLI-dependent transcription by GANT61 in human colon carcinoma cells (CC); a new therapeutic approach Cancer Research. 74: 1759-1759 |
| Mazumdar T, Sandhu R, Qadan M, et al. (2013) Hedgehog signaling regulates telomerase reverse transcriptase in human cancer cells. Plos One. 8: e75253 |
| Agyeman A, Mazumder T, Houghton J. (2013) Abstract 669: A unique acquired resistance mechanism to agents that target GLI (GANT61) in the Hedgehog (HH) signaling pathway in human colon cancer cells. Cancer Research. 73: 669-669 |
| Agyeman A, Mazumdar T, Houghton JA. (2012) Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer. Oncotarget. 3: 854-68 |
| Mazumdar T, DeVecchio J, Agyeman A, et al. (2011) The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer. Oncotarget. 2: 638-45 |
| Mazumdar T, Devecchio J, Agyeman A, et al. (2011) Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells. Cancer Research. 71: 5904-14 |
| Mazumdar T, DeVecchio J, Shi T, et al. (2011) Hedgehog signaling drives cellular survival in human colon carcinoma cells. Cancer Research. 71: 1092-102 |
| Shi T, Mazumdar T, Devecchio J, et al. (2010) cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells. Plos One. 5 |