David R Gius

Affiliations: 
Northwestern University Feinberg School of Medicine, Chicago, IL, United States 
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"David Gius"
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Kosciuczuk EM, Mehrotra S, Saleiro D, et al. (2018) Sirtuin 2-mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses. The Journal of Biological Chemistry
Song HY, Rellinger EJ, Park SH, et al. (2018) Inhibition of Sirtuin 6 Induces Neuroblastoma Differentiation. Anticancer Research. 38: 647-654
Traba J, Geiger SS, Kwarteng Siaw M, et al. (2017) Prolonged fasting suppresses mitochondrial NLRP3 inflammasome assembly and activation via SIRT3 mediated activation of Superoxide Dismutase 2. The Journal of Biological Chemistry
Vidimar V, Gius D, Chakravarti D, et al. (2016) Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas. Science Advances. 2: e1601132
Song HY, Biancucci M, Kang HJ, et al. (2016) SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status. Oncotarget
Zhang H, Head PE, Daddacha W, et al. (2016) ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA. Cell Reports
Agarwal S, Zhu Y, Gius DR, et al. (2015) Makes Caterpillars Floppy (MCFVv)-like domain of Vibrio vulnificus induces mitochondrial-mediated apoptosis. Infection and Immunity
Liu R, Fan M, Candas D, et al. (2015) CDK1-mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance. Molecular Cancer Therapeutics
Pillai VB, Samant S, Sundaresan NR, et al. (2015) Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3. Nature Communications. 6: 6656
Ozden O, Park SH, Wagner BA, et al. (2014) SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells. Free Radical Biology & Medicine. 76: 163-72
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