Alexander Titz, Ph.D.

1998-2004 Chemistry TU Darmstadt 
 2000-2001 Chemistry University of Bordeaux 1, France 
 2003-2004 Novartis Institutes of Biomedical Research, Basel 
 2004-2008 Pharmacy Universität Basel, Basel, Basel-Stadt, Switzerland 
 2008-2010 Biology Eidgenössische Technische Hochschule Zürich, Zürich, ZH, Switzerland 
 2010-2013 Chemistry University of Konstanz, Konstanz, Germany 
 2013- Helmholtz Institute for Pharmaceutical Research Saarland 
Carbohydrates, Biofilms, Glycobiology, Carbohydrate Chemistry, Medicinal Chemistry, Antiinfectives
"Alexander Titz"
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Siebs E, Shanina E, Kuhaudomlarp S, et al. (2021) Targeting the Central Pocket of the Pseudomonas aeruginosa Lectin LecA. Chembiochem : a European Journal of Chemical Biology
Wawrzinek R, Wamhoff EC, Lefebre J, et al. (2021) A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN. Journal of the American Chemical Society. 143: 18977-18988
Müller M, Calvert M, Hottmann I, et al. (2021) The exo-β-N-acetylmuramidase NamZ from Bacillus subtilis is the founding member of a family of exo-lytic peptidoglycan hexosaminidases. The Journal of Biological Chemistry. 100519
Kuhaudomlarp S, Siebs E, Shanina E, et al. (2020) Non-Carbohydrate Glycomimetics as Inhibitors of Calcium(II)-binding Lectins. Angewandte Chemie (International Ed. in English)
Meiers J, Zahorska E, Röhrig T, et al. (2020) Directing Drugs to Bugs: Antibiotic-Carbohydrate Conjugates targeting Biofilm-associated Lectins of Pseudomonas aeruginosa. Journal of Medicinal Chemistry
Zahorska E, Kuhaudomlarp S, Minervini S, et al. (2020) A rapid synthesis of low-nanomolar divalent LecA inhibitors in four linear steps from d-galactose pentaacetate. Chemical Communications (Cambridge, England)
Shanina E, Siebs E, Zhang H, et al. (2020) Protein-observed 19F NMR of LecA from Pseudomonas aeruginosa. Glycobiology
Siebert DCB, Sommer R, Pogorevc D, et al. (2019) Chemical synthesis of tripeptide thioesters for the biotechnological incorporation into the myxobacterial secondary metabolite argyrin via mutasynthesis. Beilstein Journal of Organic Chemistry. 15: 2922-2929
Sommer R, Rox K, Wagner S, et al. (2019) Anti-Biofilm Agents against Pseudomonas aeruginosa: a Structure-Activity Relationship Study of C-Glycosidic LecB Inhibitors. Journal of Medicinal Chemistry
Lepsik M, Sommer R, Kuhaudomlarp S, et al. (2019) Induction of rare conformation of oligosaccharide by binding to calcium-dependent bacterial lectin: X-ray crystallography and modelling study. European Journal of Medicinal Chemistry. 177: 212-220
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