Beat Ernst

Affiliations: 
Pharmacy University of Basel, Basel, Basel-Stadt, Switzerland 
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"Beat Ernst"

Parents

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Camille Ganter grad student ETH Zürich (Chemistry Tree)
Oskar Jeger grad student ETH Zürich (Chemistry Tree)
Robert Ellsworth Ireland post-doc Caltech (Chemistry Tree)

Collaborators

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Thomas H. Peters collaborator University of Basel (Chemistry Tree)
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Publications

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Conti G, Bärenwaldt A, Rabbani S, et al. (2023) Tetra- and Hexavalent Siglec-8 Ligands Modulate Immune Cell Activation. Angewandte Chemie (International Ed. in English). e202314280
Wawrzinek R, Wamhoff EC, Lefebre J, et al. (2021) A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN. Journal of the American Chemical Society. 143: 18977-18988
Kroezen B, Conti G, Girardi B, et al. (2020) A Potent Mimetic of the Siglec-8 Ligand 6'-Sulfo-Sialyl Lewisx. Chemmedchem
de Matos AM, Martins A, Man T, et al. (2019) Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against HO- and Aβ-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells. Pharmaceuticals (Basel, Switzerland). 12
Cramer J, Sager CP, Ernst B. (2019) Hydroxyl Groups in Synthetic and Natural Product Derived Therapeutics - A Perspective on a Common Functional Group. Journal of Medicinal Chemistry
Sauer MM, Jakob RP, Luber T, et al. (2019) Binding of the Bacterial Adhesin FimH to Its Natural, Multivalent High-Mannose Type Glycan Targets. Journal of the American Chemical Society. 141: 936-944
Frei P, Hevey R, Ernst B. (2019) Dynamic Combinatorial Chemistry: A New Methodology Comes of Age. Chemistry (Weinheim An Der Bergstrasse, Germany). 25: 60-73
Schönemann W, Cramer J, Mühlethaler T, et al. (2019) Improvement of Aglycone pi-Stacking Yields Nanomolar to Sub-nanomolar FimH Antagonists. Chemmedchem. 14: 749-757
Dias C, Matos AM, Blásquez-Sanchez MT, et al. (2019) 2-Deoxyglycosylation towards more effective and bioavailable neuroprotective molecules inspired by nature Pure and Applied Chemistry. 91: 1209-1221
Ernst B, Zihlmann P, Slbermann M, et al. (2018) KinITC - One method supports both thermodynamic and kinetic SARs as exemplified on FimH antagonists. Chemistry (Weinheim An Der Bergstrasse, Germany)
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