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Alvin John Clark, PhD

Affiliations: 
Molecular Biology University of California, Berkeley, CA, United States 
Area:
Homologous recombination, recA and recBC pathways
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"Alvin Clark"
Bio:

Discoverer of recA, recB, recC, and recF genes; discovered that homologous recombination in E. coli is mediated chiefly by the recA gene; studied UV radiation sensitivity of E. coli by epistasis analysis, which became the basis of understanding the enzymology of homologous recombination. (Deceased)

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Ronald A Skurray post-doc UC Berkeley

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Lanzov VA, Bakhlanova IV, Clark AJ. (2003) Conjugational hyperrecombination achieved by derepressing the LexA regulon, altering the properties of RecA protein and inactivating mismatch repair in Escherichia coli K-12. Genetics. 163: 1243-54
Sandler SJ, Marians KJ, Zavitz KH, et al. (1999) dnaC mutations suppress defects in DNA replication- and recombination-associated functions in priB and priC double mutants in Escherichia coli K-12. Molecular Microbiology. 34: 91-101
Sandler SJ, Hugenholtz P, Schleper C, et al. (1999) Diversity of radA genes from cultured and uncultured archaea: comparative analysis of putative RadA proteins and their use as a phylogenetic marker. Journal of Bacteriology. 181: 907-15
Dhillon TS, Poon AP, Chan D, et al. (1998) General transducing phages like Salmonella phage P22 isolated using a smooth strain of Escherichia coli as host. Fems Microbiology Letters. 161: 129-33
Kim R, Sandler SJ, Goldman S, et al. (1998) Overexpression of archaeal proteins in Escherichia coli Biotechnology Letters. 20: 207-210
Brendel V, Brocchieri L, Sandler SJ, et al. (1997) Evolutionary comparisons of RecA-like proteins across all major kingdoms of living organisms. Journal of Molecular Evolution. 44: 528-41
Hegde SP, Qin MH, Li XH, et al. (1996) Interactions of RecF protein with RecO, RecR, and single-stranded DNA binding proteins reveal roles for the RecF–RecO–RecR complex in DNA repair and recombination Proceedings of the National Academy of Sciences of the United States of America. 93: 14468-14473
Clark AJ. (1996) recA mutants of E. coli K12: A personal turning point Bioessays. 18: 767-772
Sandler SJ, Satin LH, Samra HS, et al. (1996) recA-like genes from three archaean species with putative protein products similar to Rad51 and Dmc1 proteins of the yeast Saccharomyces cerevisiae. Nucleic Acids Research. 24: 2125-32
Hegde S, Sandler SJ, Clark AJ, et al. (1995) recO and recR mutations delay induction of the SOS response in Escherichia coli. Molecular & General Genetics : Mgg. 246: 254-8
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