Kristina Haslinger

Affiliations: 
Rijksuniversiteit Groningen, Chemical and Pharmaceutical Biology 
Area:
natural product discovery, metabolic engineering
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"Kristina Haslinger"
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Publications

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Peschke M, Haslinger K, Brieke C, et al. (2016) Regulation of the P450 Oxygenation Cascade Involved in Glycopeptide Antibiotic Biosynthesis. Journal of the American Chemical Society. 138: 6746-53
Haslinger K, Cryle MJ. (2016) Structure of OxyA tei: completing our picture of the glycopeptide antibiotic producing Cytochrome P450 cascade. Febs Letters. 590: 571-81
Brieke C, Peschke M, Haslinger K, et al. (2015) Sequential In Vitro Cyclization by Cytochrome P450 Enzymes of Glycopeptide Antibiotic Precursors Bearing the X-Domain from Nonribosomal Peptide Biosynthesis. Angewandte Chemie (International Ed. in English). 54: 15715-9
Haslinger K, Peschke M, Brieke C, et al. (2015) X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis. Nature. 521: 105-9
Haslinger K, Redfield C, Cryle MJ. (2015) Structure of the terminal PCP domain of the non-ribosomal peptide synthetase in teicoplanin biosynthesis. Proteins. 83: 711-21
Brieke C, Kratzig V, Haslinger K, et al. (2015) Rapid access to glycopeptide antibiotic precursor peptides coupled with cytochrome P450-mediated catalysis: towards a biomimetic synthesis of glycopeptide antibiotics. Organic & Biomolecular Chemistry. 13: 2012-21
Haslinger K, Maximowitsch E, Brieke C, et al. (2014) Cytochrome P450 OxyBtei catalyzes the first phenolic coupling step in teicoplanin biosynthesis. Chembiochem : a European Journal of Chemical Biology. 15: 2719-28
Haslinger K, Brieke C, Uhlmann S, et al. (2014) The structure of a transient complex of a nonribosomal peptide synthetase and a cytochrome P450 monooxygenase. Angewandte Chemie (International Ed. in English). 53: 8518-22
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