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Dennis Chun-Yone Ko - Publications

Affiliations: 
2003 Stanford University, Palo Alto, CA 
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Gibbs KD, Washington EJ, Jaslow SL, Bourgeois JS, Foster MW, Guo R, Brennan RG, Ko DC. The Salmonella Secreted Effector SarA/SteE Mimics Cytokine Receptor Signaling to Activate STAT3. Cell Host & Microbe. PMID 31901521 DOI: 10.1016/J.Chom.2019.11.012  0.301
2019 Antonia AL, Gibbs KD, Trahair ED, Pittman KJ, Martin AT, Schott BH, Smith JS, Rajagopal S, Thompson JW, Reinhardt RL, Ko DC. Pathogen Evasion of Chemokine Response Through Suppression of CXCL10. Frontiers in Cellular and Infection Microbiology. 9: 280. PMID 31440475 DOI: 10.3389/Fcimb.2019.00280  0.344
2018 Wang L, Pittman KJ, Barker JR, Salinas RE, Stanaway IB, Williams GD, Carroll RJ, Balmat T, Ingham A, Gopalakrishnan AM, Gibbs KD, Antonia AL, Heitman J, Lee SC, ... ... Ko DC, et al. An Atlas of Genetic Variation Linking Pathogen-Induced Cellular Traits to Human Disease. Cell Host & Microbe. 24: 308-323.e6. PMID 30092202 DOI: 10.1016/J.Chom.2018.07.007  0.406
2018 Jaslow SL, Gibbs KD, Fricke WF, Wang L, Pittman KJ, Mammel MK, Thaden JT, Fowler VG, Hammer GE, Elfenbein JR, Ko DC. Salmonella Activation of STAT3 Signaling by SarA Effector Promotes Intracellular Replication and Production of IL-10. Cell Reports. 23: 3525-3536. PMID 29924996 DOI: 10.1016/J.Celrep.2018.05.072  0.333
2018 Bourgeois JS, Zhou D, Thurston TLM, Gilchrist JJ, Ko DC. Methylthioadenosine suppresses virulence. Infection and Immunity. PMID 29866910 DOI: 10.1128/Iai.00429-18  0.35
2018 Corona E, Wang L, Ko D, Patel CJ. Systematic detection of positive selection in the human-pathogen interactome and lasting effects on infectious disease susceptibility. Plos One. 13: e0196676. PMID 29799843 DOI: 10.1371/Journal.Pone.0196676  0.339
2017 Alvarez MI, Glover LC, Luo P, Wang L, Theusch E, Oehlers SH, Walton EM, Tram TTB, Kuang YL, Rotter JI, McClean CM, Chinh NT, Medina MW, Tobin DM, Dunstan SJ, ... Ko DC, et al. Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol. Proceedings of the National Academy of Sciences of the United States of America. PMID 28827342 DOI: 10.1073/Pnas.1706070114  0.394
2017 Wang L, Ko ER, Gilchrist JJ, Pittman KJ, Rautanen A, Pirinen M, Thompson JW, Dubois LG, Langley RJ, Jaslow SL, Salinas RE, Rouse DC, Moseley MA, Mwarumba S, Njuguna P, ... ... Ko DC, et al. Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis. Science Advances. 3: e1602096. PMID 28345042 DOI: 10.1126/Sciadv.1602096  0.343
2016 Pittman KJ, Glover LC, Wang L, Ko DC. The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease. Plos Pathogens. 12: e1005680. PMID 27442518 DOI: 10.1371/Journal.Ppat.1005680  0.349
2015 Jaslow S, Wang L, Ko D. Contribution to Virulence of a Novel Anti-inflammatory Effector in Salmonella enterica. Open Forum Infectious Diseases. 2: 693. PMID 27437422 DOI: 10.1093/Ofid/Ofv131.68  0.34
2015 Wang L, Oehlers SH, Espenschied ST, Rawls JF, Tobin DM, Ko DC. CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation. Genome Biology. 16: 190. PMID 26374098 DOI: 10.1186/S13059-015-0722-1  0.327
2015 McCauliff LA, Xu Z, Li R, Kodukula S, Ko DC, Scott MP, Kahn PC, Storch J. Multiple Surface Regions on the Niemann-Pick C2 Protein Facilitate Intracellular Cholesterol Transport. The Journal of Biological Chemistry. PMID 26296895 DOI: 10.1074/Jbc.M115.667469  0.515
2015 Lee SC, Li A, Calo S, Inoue M, Tonthat NK, Bain JM, Louw J, Shinohara ML, Erwig LP, Schumacher MA, Ko DC, Heitman J. Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host-pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides. Molecular Microbiology. PMID 26010100 DOI: 10.1111/Mmi.13071  0.343
2014 Salinas RE, Ogohara C, Thomas MI, Shukla KP, Miller SI, Ko DC. A cellular genome-wide association study reveals human variation in microtubule stability and a role in inflammatory cell death. Molecular Biology of the Cell. 25: 76-86. PMID 24173717 DOI: 10.1091/Mbc.E13-06-0294  0.536
2013 Ko DC, Urban TJ. Understanding human variation in infectious disease susceptibility through clinical and cellular GWAS. Plos Pathogens. 9: e1003424. PMID 23935492 DOI: 10.1371/Journal.Ppat.1003424  0.371
2012 Ko DC, Gamazon ER, Shukla KP, Pfuetzner RA, Whittington D, Holden TD, Brittnacher MJ, Fong C, Radey M, Ogohara C, Stark AL, Akey JM, Dolan ME, Wurfel MM, Miller SI. Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death. Proceedings of the National Academy of Sciences of the United States of America. 109: E2343-52. PMID 22837397 DOI: 10.1073/Pnas.1206701109  0.562
2012 Tobin DM, Roca FJ, Oh SF, McFarland R, Vickery TW, Ray JP, Ko DC, Zou Y, Bang ND, Chau TT, Vary JC, Hawn TR, Dunstan SJ, Farrar JJ, Thwaites GE, et al. Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell. 148: 434-46. PMID 22304914 DOI: 10.1016/J.Cell.2011.12.023  0.31
2011 McElwain MA, Ko DC, Gordon MD, Fyrst H, Saba JD, Nusse R. A suppressor/enhancer screen in Drosophila reveals a role for wnt-mediated lipid metabolism in primordial germ cell migration. Plos One. 6: e26993. PMID 22069480 DOI: 10.1371/Journal.Pone.0026993  0.353
2010 Vinh DB, Ko DC, Rachubinski RA, Aitchison JD, Miller SI. Expression of the Salmonella spp. virulence factor SifA in yeast alters Rho1 activity on peroxisomes. Molecular Biology of the Cell. 21: 3567-77. PMID 20739463 DOI: 10.1091/Mbc.E10-06-0482  0.507
2010 Fong C, Ko DC, Wasnick M, Radey M, Miller SI, Brittnacher M. GWAS analyzer: integrating genotype, phenotype and public annotation data for genome-wide association study analysis. Bioinformatics (Oxford, England). 26: 560-4. PMID 20053839 DOI: 10.1093/Bioinformatics/Btp714  0.485
2010 McElwain MA, Ko DC, Gordon MD, Nusse R. A crucial role for lipid phosphorylation in WntD-mediated primordial germ cell migration Developmental Biology. 344: 512. DOI: 10.1016/J.Ydbio.2010.05.358  0.304
2009 Ko DC, Shukla KP, Fong C, Wasnick M, Brittnacher MJ, Wurfel MM, Holden TD, O'Keefe GE, Van Yserloo B, Akey JM, Miller SI. A genome-wide in vitro bacterial-infection screen reveals human variation in the host response associated with inflammatory disease. American Journal of Human Genetics. 85: 214-27. PMID 19664744 DOI: 10.1016/J.Ajhg.2009.07.012  0.55
2005 Ko DC, Milenkovic L, Beier SM, Manuel H, Buchanan J, Scott MP. Cell-autonomous death of cerebellar purkinje neurons with autophagy in Niemann-Pick type C disease. Plos Genetics. 1: 81-95. PMID 16103921 DOI: 10.1371/Journal.Pgen.0010007  0.545
2005 Ko DC, Milenkovic L, Beier SM, Manuel H, Buchanan J, Scott MP. Correction: Cell-Autonomous Death of Cerebellar Purkinje Neurons with Autophagy in Niemann-Pick Type C Disease Plos Genetics. 1: e86. DOI: 10.1371/Journal.Pgen.0010086  0.481
2004 Ohgami N, Ko DC, Thomas M, Scott MP, Chang CC, Chang TY. Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain. Proceedings of the National Academy of Sciences of the United States of America. 101: 12473-8. PMID 15314240 DOI: 10.1073/Pnas.0405255101  0.513
2003 Ko DC, Binkley J, Sidow A, Scott MP. The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels. Proceedings of the National Academy of Sciences of the United States of America. 100: 2518-25. PMID 12591949 DOI: 10.1073/Pnas.0530027100  0.532
2001 Ko DC, Gordon MD, Jin JY, Scott MP. Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events. Molecular Biology of the Cell. 12: 601-14. PMID 11251074 DOI: 10.1091/Mbc.12.3.601  0.542
1998 Ko DC, Marr MT, Guo J, Roberts JW. A surface of Escherichia coli sigma 70 required for promoter function and antitermination by phage lambda Q protein. Genes & Development. 12: 3276-85. PMID 9784501 DOI: 10.1101/Gad.12.20.3276  0.3
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