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Magdy M. Mahfouz, Ph.D. - Publications

Affiliations: 
Ohio State University, Columbus, Columbus, OH 
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71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sedeek K, Mohammed N, Zhou Y, Zuccolo A, Sanikommu K, Kantharajappa S, Al-Bader N, Tashkandi M, Wing RA, Mahfouz MM. Multitrait engineering of Hassawi red rice for sustainable cultivation. Plant Science : An International Journal of Experimental Plant Biology. 341: 112018. PMID 38325660 DOI: 10.1016/j.plantsci.2024.112018  0.334
2024 Sivakrishna Rao G, Saleh AH, Melliti F, Muntjeeb S, Mahfouz M. Harnessing Peptide Nucleic Acids and the Eukaryotic Resolvase MOC1 for Programmable, Precise Generation of Double-Strand DNA Breaks. Analytical Chemistry. PMID 38300270 DOI: 10.1021/acs.analchem.3c05133  0.302
2023 Marsic T, Gundra SR, Wang Q, Aman R, Mahas A, Mahfouz MM. Programmable site-specific DNA double-strand breaks via PNA-assisted prokaryotic Argonautes. Nucleic Acids Research. PMID 37560931 DOI: 10.1093/nar/gkad655  0.4
2022 Jiang W, Sivakrishna Rao G, Aman R, Butt H, Kamel R, Sedeek K, Mahfouz MM. High-efficiency retron-mediated single-stranded DNA production in plants. Synthetic Biology (Oxford, England). 7: ysac025. PMID 36452068 DOI: 10.1093/synbio/ysac025  0.379
2022 Butt H, Ramirez JLM, Mahfouz M. Synthetic evolution of herbicide resistance using a T7 RNAP-based random DNA base editor. Life Science Alliance. 5. PMID 36171140 DOI: 10.26508/lsa.202201538  0.347
2021 Mahas A, Wang Q, Marsic T, Mahfouz MM. A Novel Miniature CRISPR-Cas13 System for SARS-CoV-2 Diagnostics. Acs Synthetic Biology. PMID 34546709 DOI: 10.1021/acssynbio.1c00181  0.308
2021 Rao GS, Jiang W, Mahfouz M. Synthetic directed evolution in plants: unlocking trait engineering and improvement. Synthetic Biology (Oxford, England). 6: ysab025. PMID 34522785 DOI: 10.1093/synbio/ysab025  0.34
2021 Cable J, Ronald PC, Voytas D, Zhang F, Levy AA, Takatsuka A, Arimura SI, Jacobsen SE, Toki S, Toda E, Gao C, Zhu JK, Boch J, Van Eck J, Mahfouz M, et al. Plant genome engineering from lab to field-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 34435370 DOI: 10.1111/nyas.14675  0.383
2021 Butt H, Bazin J, Alshareef S, Eid A, Benhamed M, Reddy ASN, Crespi M, Mahfouz MM. Overlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation. Communications Biology. 4: 529. PMID 33953336 DOI: 10.1038/s42003-021-02051-y  0.755
2020 Schmitz DJ, Ali Z, Wang C, Aljedaani F, Hooykaas PJJ, Mahfouz M, de Pater S. CRISPR/Cas9 Mutagenesis by Translocation of Cas9 Protein Into Plant Cells via the Type IV Secretion System. Frontiers in Genome Editing. 2: 6. PMID 34713215 DOI: 10.3389/fgeed.2020.00006  0.385
2020 Zafar K, Sedeek KEM, Rao GS, Khan MZ, Amin I, Kamel R, Mukhtar Z, Zafar M, Mansoor S, Mahfouz MM. Genome Editing Technologies for Rice Improvement: Progress, Prospects, and Safety Concerns. Frontiers in Genome Editing. 2: 5. PMID 34713214 DOI: 10.3389/fgeed.2020.00005  0.359
2020 Aman R, Mahas A, Marsic T, Hassan N, Mahfouz MM. Efficient, Rapid, and Sensitive Detection of Plant RNA Viruses With One-Pot RT-RPA-CRISPR/Cas12a Assay. Frontiers in Microbiology. 11: 610872. PMID 33391239 DOI: 10.3389/fmicb.2020.610872  0.31
2020 Zaidi SS, Mahas A, Vanderschuren H, Mahfouz MM. Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants. Genome Biology. 21: 289. PMID 33256828 DOI: 10.1186/s13059-020-02204-y  0.315
2020 Ali Z, Aman R, Mahas A, Rao GS, Tehseen M, Marsic T, Salunke R, Subudhi AK, Hala SM, Hamdan SM, Pain A, Alofi FS, Alsomali A, Hashem AM, Khogeer A, ... ... Mahfouz MM, et al. iSCAN: An RT-LAMP-coupled CRISPR-Cas12 module for rapid, sensitive detection of SARS-CoV-2. Virus Research. 198129. PMID 32822689 DOI: 10.1016/J.Virusres.2020.198129  0.311
2020 Butt H, Rao GS, Sedeek KEM, Aman R, Kamel R, Mahfouz MM. Engineering herbicide resistance via prime editing in rice. Plant Biotechnology Journal. PMID 32415890 DOI: 10.1111/Pbi.13399  0.438
2020 Kim S, Piquerez SJM, Ramirez-Prado JS, Mastorakis E, Veluchamy A, Latrasse D, Manza-Mianza D, Brik-Chaouche R, Huang Y, Rodriguez-Granados NY, Concia L, Blein T, Citerne S, Bendahmane A, Bergounioux C, ... ... Mahfouz MM, et al. GCN5 modulates salicylic acid homeostasis by regulating H3K14ac levels at the 5' and 3' ends of its target genes. Nucleic Acids Research. PMID 32396165 DOI: 10.1093/Nar/Gkaa369  0.446
2020 Concia L, Veluchamy A, Ramirez-Prado JS, Martin-Ramirez A, Huang Y, Perez M, Domenichini S, Rodriguez Granados NY, Kim S, Blein T, Duncan S, Pichot C, Manza-Mianza D, Juery C, Paux E, ... ... Mahfouz MM, et al. Wheat chromatin architecture is organized in genome territories and transcription factories. Genome Biology. 21: 104. PMID 32349780 DOI: 10.1186/S13059-020-01998-1  0.442
2020 Aman R, Mahas A, Mahfouz M. Nucleic Acid Detection Using CRISPR/Cas Biosensing Technologies. Acs Synthetic Biology. 9: 1226-1233. PMID 32159950 DOI: 10.1021/Acssynbio.9B00507  0.377
2020 Ali Z, Shami A, Sedeek K, Kamel R, Alhabsi A, Tehseen M, Hassan N, Butt H, Kababji A, Hamdan SM, Mahfouz MM. Fusion of the Cas9 endonuclease and the VirD2 relaxase facilitates homology-directed repair for precise genome engineering in rice. Communications Biology. 3: 44. PMID 31974493 DOI: 10.1038/s42003-020-0768-9  0.495
2019 Ali Z, Mahfouz MM, Mansoor S. CRISPR-TSKO: A Tool for Tissue-Specific Genome Editing in Plants. Trends in Plant Science. PMID 31859038 DOI: 10.1016/J.Tplants.2019.12.002  0.476
2019 Mahas A, Aman R, Mahfouz MM. CRISPR-Cas13d Mediates Robust RNA Virus Interference in Plants Genome Biology. 20: 1-16. PMID 31791381 DOI: 10.1186/S13059-019-1881-2  0.432
2019 Butt H, Zaidi SS, Hassan N, Mahfouz M. CRISPR-Based Directed Evolution for Crop Improvement. Trends in Biotechnology. PMID 31477243 DOI: 10.1016/J.Tibtech.2019.08.001  0.496
2019 Ali Z, Zaidi SS, Tashkandi M, Mahfouz MM. A Simplified Method to Engineer CRISPR/Cas9-Mediated Geminivirus Resistance in Plants. Methods in Molecular Biology (Clifton, N.J.). 2028: 167-183. PMID 31228115 DOI: 10.1007/978-1-4939-9635-3_10  0.554
2019 Morton M, AlTamimi N, Butt H, Reddy ASN, Mahfouz M. Serine/Arginine-rich protein family of splicing regulators: New approaches to study splice isoform functions. Plant Science : An International Journal of Experimental Plant Biology. 283: 127-134. PMID 31128682 DOI: 10.1016/J.Plantsci.2019.02.017  0.412
2019 Butt H, Eid A, Momin AA, Bazin J, Crespi M, Arold ST, Mahfouz MM. CRISPR directed evolution of the spliceosome for resistance to splicing inhibitors. Genome Biology. 20: 73. PMID 31036069 DOI: 10.1186/S13059-019-1680-9  0.748
2019 Sedeek KEM, Mahas A, Mahfouz MM. Plant Genome Engineering for Targeted Improvement of Crop Traits Frontiers in Plant Science. 10: 114. PMID 30809237 DOI: 10.3389/Fpls.2019.00114  0.516
2019 Mahas A, Ali Z, Tashkandi M, Mahfouz MM. Virus-Mediated Genome Editing in Plants Using the CRISPR/Cas9 System. Methods in Molecular Biology (Clifton, N.J.). 1917: 311-326. PMID 30610646 DOI: 10.1007/978-1-4939-8991-1_23  0.574
2018 Aman R, Mahas A, Butt H, Aljedaani F, Mahfouz M. Engineering RNA Virus Interference via the CRISPR/Cas13 Machinery in Arabidopsis Viruses. 10: 732. PMID 30572690 DOI: 10.3390/V10120732  0.482
2018 Tashkandi M, Ali Z, Aljedaani F, Shami A, Mahfouz MM. Engineering resistance against Tomato yellow leaf curl virus via the CRISPR/Cas9 system in tomato. Plant Signaling & Behavior. 1-7. PMID 30289378 DOI: 10.1080/15592324.2018.1525996  0.513
2018 Butt H, Jamil M, Wang JY, Al-Babili S, Mahfouz M. Engineering plant architecture via CRISPR/Cas9-mediated alteration of strigolactone biosynthesis. Bmc Plant Biology. 18: 174. PMID 30157762 DOI: 10.1186/S12870-018-1387-1  0.49
2018 Mahas A, Mahfouz M. Engineering virus resistance via CRISPR-Cas systems. Current Opinion in Virology. 32: 1-8. PMID 30005359 DOI: 10.1016/J.Coviro.2018.06.002  0.401
2018 Eid A, Alshareef S, Mahfouz MM. CRISPR base editors: genome editing without double-stranded breaks. The Biochemical Journal. 475: 1955-1964. PMID 29891532 DOI: 10.1042/Bcj20170793  0.787
2018 Ali Z, Mahas A, Mahfouz M. CRISPR/Cas13 as a Tool for RNA Interference. Trends in Plant Science. PMID 29605099 DOI: 10.1016/J.Tplants.2018.03.003  0.375
2018 Ling Y, Serrano N, Gao G, Atia M, Mokhtar M, Woo YH, Bazin J, Veluchamy A, Benhamed M, Crespi M, Gehring C, Reddy ASN, Mahfouz MM. Thermopriming Triggers Splicing Memory in Arabidopsis. Journal of Experimental Botany. PMID 29474581 DOI: 10.1093/Jxb/Ery062  0.308
2018 Aman R, Ali Z, Butt H, Mahas A, Aljedaani F, Khan MZ, Ding S, Mahfouz M. RNA virus interference via CRISPR/Cas13a system in plants. Genome Biology. 19: 1. PMID 29301551 DOI: 10.1186/S13059-017-1381-1  0.451
2017 Mahas A, Neal Stewart C, Mahfouz MM. Harnessing CRISPR/Cas systems for programmable transcriptional and post-transcriptional regulation. Biotechnology Advances. PMID 29197619 DOI: 10.1016/J.Biotechadv.2017.11.008  0.454
2017 Ali Z, Eid A, Ali S, Mahfouz MM. Pea early-browning virus-mediated genome editing via the CRISPR/Cas9 system in Nicotiana benthamiana and Arabidopsis. Virus Research. PMID 29051052 DOI: 10.1016/J.Virusres.2017.10.009  0.798
2017 Butt H, Eid A, Ali Z, Atia MAM, Mokhtar MM, Hassan N, Lee CM, Bao G, Mahfouz MM. Efficient CRISPR/Cas9-Mediated Genome Editing Using a Chimeric Single-Guide RNA Molecule. Frontiers in Plant Science. 8: 1441. PMID 28883826 DOI: 10.3389/Fpls.2017.01441  0.791
2017 Zaidi SS, Tashkandi M, Mahfouz MM. Engineering Molecular Immunity Against Plant Viruses. Progress in Molecular Biology and Translational Science. 149: 167-186. PMID 28712496 DOI: 10.1016/Bs.Pmbts.2017.03.009  0.552
2017 Jégu T, Veluchamy A, Ramirez-Prado JS, Rizzi-Paillet C, Perez M, Lhomme A, Latrasse D, Coleno E, Vicaire S, Legras S, Jost B, Rougée M, Barneche F, Bergounioux C, Crespi M, ... Mahfouz MM, et al. The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility. Genome Biology. 18: 114. PMID 28619072 DOI: 10.1186/S13059-017-1246-7  0.345
2017 Zaidi SS, Mahfouz MM, Mansoor S. CRISPR-Cpf1: A New Tool for Plant Genome Editing. Trends in Plant Science. PMID 28532598 DOI: 10.1016/J.Tplants.2017.05.001  0.549
2017 AlShareef S, Ling Y, Butt H, Mariappan KG, Benhamed M, Mahfouz MM. Herboxidiene triggers splicing repression and abiotic stress responses in plants. Bmc Genomics. 18: 260. PMID 28347276 DOI: 10.1186/S12864-017-3656-Z  0.336
2017 Mahfouz MM. Genome editing: The efficient tool CRISPR-Cpf1. Nature Plants. 3: 17028. PMID 28260792 DOI: 10.1038/Nplants.2017.28  0.572
2016 Aouida M, Eid A, Mahfouz MM. CRISPR/Cas9-mediated target validation of the splicing inhibitor Pladienolide B. Biochimie Open. 3: 72-75. PMID 29450134 DOI: 10.1016/J.Biopen.2016.02.001  0.776
2016 Zaidi SS, Tashkandi M, Mansoor S, Mahfouz MM. Engineering Plant Immunity: Using CRISPR/Cas9 to Generate Virus Resistance. Frontiers in Plant Science. 7: 1673. PMID 27877187 DOI: 10.3389/Fpls.2016.01673  0.53
2016 Eid A, Mahfouz MM. Genome editing: the road of CRISPR/Cas9 from bench to clinic. Experimental & Molecular Medicine. 48: e265. PMID 27741224 DOI: 10.1038/Emm.2016.111  0.786
2016 Ling Y, Alshareef S, Butt H, Lozano-Juste J, Li L, Galal AA, Moustafa A, Momin AA, Tashkandi M, Richardson DN, Fujii H, Arold S, Rodriguez PL, Duque P, Mahfouz MM. Pre-mRNA splicing repression triggers abiotic stress signaling in plants. The Plant Journal : For Cell and Molecular Biology. PMID 27664942 DOI: 10.1111/Tpj.13383  0.393
2016 Mahfouz MM, Cardi T, Neal Stewart C. Next-generation precision genome engineering and plant biotechnology. Plant Cell Reports. PMID 27271686 DOI: 10.1007/S00299-016-2009-8  0.488
2016 Eid A, Ali Z, Mahfouz MM. High efficiency of targeted mutagenesis in arabidopsis via meiotic promoter-driven expression of Cas9 endonuclease. Plant Cell Reports. PMID 27236699 DOI: 10.1007/S00299-016-2000-4  0.789
2016 Ali Z, Ali S, Tashkandi M, Zaidi SS, Mahfouz MM. CRISPR/Cas9-Mediated Immunity to Geminiviruses: Differential Interference and Evasion. Scientific Reports. 6: 26912. PMID 27225592 DOI: 10.1038/Srep26912  0.476
2016 Piatek A, Mahfouz MM. Targeted genome regulation via synthetic programmable transcriptional regulators. Critical Reviews in Biotechnology. 1-12. PMID 27093352 DOI: 10.3109/07388551.2016.1165180  0.543
2016 Zaidi SS, Mansoor S, Ali Z, Tashkandi M, Mahfouz MM. Engineering Plants for Geminivirus Resistance with CRISPR/Cas9 System. Trends in Plant Science. PMID 26880316 DOI: 10.1016/J.Tplants.2016.01.023  0.471
2015 Ali Z, Abulfaraj A, Idris A, Ali S, Tashkandi M, Mahfouz MM. CRISPR/Cas9-mediated viral interference in plants. Genome Biology. 16: 238. PMID 26556628 DOI: 10.1186/S13059-015-0799-6  0.526
2015 Aouida M, Eid A, Ali Z, Cradick T, Lee C, Deshmukh H, Atef A, AbuSamra D, Gadhoum SZ, Merzaban J, Bao G, Mahfouz M. Efficient fdCas9 Synthetic Endonuclease with Improved Specificity for Precise Genome Engineering. Plos One. 10: e0133373. PMID 26225561 DOI: 10.1371/Journal.Pone.0133373  0.795
2015 Ali Z, Abul-Faraj A, Piatek M, Mahfouz MM. Activity and Specificity of TRV-Mediated Gene Editing in Plants. Plant Signaling & Behavior. 0. PMID 26039254 DOI: 10.1080/15592324.2015.1044191  0.587
2015 Aouida M, Li L, Mahjoub A, Alshareef S, Ali Z, Piatek A, Mahfouz MM. Transcription activator-like effector nucleases mediated metabolic engineering for enhanced fatty acids production in Saccharomyces cerevisiae. Journal of Bioscience and Bioengineering. PMID 25907574 DOI: 10.1016/J.Jbiosc.2015.02.017  0.474
2015 Ali Z, Abul-Faraj A, Li L, Ghosh N, Piatek M, Mahjoub A, Aouida M, Piatek A, Baltes NJ, Voytas DF, Dinesh-Kumar S, Mahfouz MM. Efficient Virus-Mediated Genome Editing in Plants Using the CRISPR/Cas9 System. Molecular Plant. 8: 1288-91. PMID 25749112 DOI: 10.1016/J.Molp.2015.02.011  0.546
2015 Piatek A, Ali Z, Baazim H, Li L, Abulfaraj A, Al-Shareef S, Aouida M, Mahfouz MM. RNA-guided transcriptional regulation in planta via synthetic dCas9-based transcription factors. Plant Biotechnology Journal. 13: 578-89. PMID 25400128 DOI: 10.1111/Pbi.12284  0.52
2015 Aouida M, Eid A, Ali Z, Cradick T, Lee C, Deshmukh H, Atef A, Abusamra D, Gadhoum SZ, Merzaban J, Bao G, Mahfouz M. Efficient fdCas9 synthetic endonuclease with improved specificity for precise genome engineering Plos One. 10. DOI: 10.1371/journal.pone.0133373  0.365
2014 Mahfouz MM, Piatek A, Stewart CN. Genome engineering via TALENs and CRISPR/Cas9 systems: challenges and perspectives. Plant Biotechnology Journal. 12: 1006-14. PMID 25250853 DOI: 10.1111/Pbi.12256  0.605
2014 Shokry AM, Al-Karim S, Ramadan A, Gadallah N, Al Attas SG, Sabir JSM, Hassan SM, Madkour MA, Bressan R, Mahfouz M, Bahieldin A. Detection of a Usp-like gene in Calotropis procera plant from the de novo assembled genome contigs of the high-throughput sequencing dataset Comptes Rendus - Biologies. 337: 86-94. PMID 24581802 DOI: 10.1016/J.Crvi.2013.12.008  0.433
2014 Aouida M, Piatek MJ, Bangarusamy DK, Mahfouz MM. Activities and specificities of homodimeric TALENs in Saccharomyces cerevisiae. Current Genetics. 60: 61-74. PMID 24081604 DOI: 10.1007/S00294-013-0412-Z  0.491
2013 Li L, Atef A, Piatek A, Ali Z, Piatek M, Aouida M, Sharakuu A, Mahjoub A, Wang G, Khan S, Fedoroff NV, Zhu JK, Mahfouz MM. Characterization and DNA-binding specificities of Ralstonia TAL-like effectors. Molecular Plant. 6: 1318-30. PMID 23300258 DOI: 10.1093/Mp/Sst006  0.416
2012 Li L, Piatek MJ, Atef A, Piatek A, Wibowo A, Fang X, Sabir JS, Zhu JK, Mahfouz MM. Rapid and highly efficient construction of TALE-based transcriptional regulators and nucleases for genome modification. Plant Molecular Biology. 78: 407-16. PMID 22271303 DOI: 10.1007/S11103-012-9875-4  0.551
2012 Deng D, Yan C, Pan X, Mahfouz M, Wang J, Zhu JK, Shi Y, Yan N. Structural basis for sequence-specific recognition of DNA by TAL effectors. Science (New York, N.Y.). 335: 720-3. PMID 22223738 DOI: 10.1126/Science.1215670  0.346
2012 Mahfouz MM, Li L, Piatek M, Fang X, Mansour H, Bangarusamy DK, Zhu JK. Targeted transcriptional repression using a chimeric TALE-SRDX repressor protein. Plant Molecular Biology. 78: 311-21. PMID 22167390 DOI: 10.1007/S11103-011-9866-X  0.506
2011 Mahfouz MM, Li L. TALE nucleases and next generation GM crops. Gm Crops. 2: 99-103. PMID 21865862 DOI: 10.4161/Gmcr.2.2.17254  0.553
2011 Mahfouz MM, Li L, Shamimuzzaman M, Wibowo A, Fang X, Zhu JK. De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks. Proceedings of the National Academy of Sciences of the United States of America. 108: 2623-8. PMID 21262818 DOI: 10.1073/Pnas.1019533108  0.508
2010 Mahfouz MM. RNA-directed DNA methylation: mechanisms and functions. Plant Signaling & Behavior. 5: 806-16. PMID 20421728 DOI: 10.4161/Psb.5.7.11695  0.455
2006 Mahfouz MM, Kim S, Delauney AJ, Verma DP. Arabidopsis TARGET OF RAPAMYCIN interacts with RAPTOR, which regulates the activity of S6 kinase in response to osmotic stress signals. The Plant Cell. 18: 477-90. PMID 16377759 DOI: 10.1105/Tpc.105.035931  0.336
2005 Dong X, Hong Z, Sivaramakrishnan M, Mahfouz M, Verma DP. Callose synthase (CalS5) is required for exine formation during microgametogenesis and for pollen viability in Arabidopsis. The Plant Journal : For Cell and Molecular Biology. 42: 315-28. PMID 15842618 DOI: 10.1111/J.1365-313X.2005.02379.X  0.511
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