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Steven J. Metallo - Publications

Affiliations: 
2001- Chemistry Georgetown University, Washington, DC 
Area:
chemical biology, biophysical chemistry, and surface chemistry
Website:
https://chemistry.georgetown.edu/Metallo
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Jaiprashad R, De Silva SR, Fred Lucena LM, Meyer E, Metallo SJ. Portability of a Small-Molecule Binding Site between Disordered Proteins. Biomolecules. 12. PMID 36551315 DOI: 10.3390/biom12121887  0.563
2022 Meyer E, DeSilva SR, Metallo SJ. Portability of Small Molecule Binding Sites in Intrinsically Disordered Proteins. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35553590 DOI: 10.1096/fasebj.2022.36.S1.L8044  0.569
2018 Dobrev VS, Fred LM, Gerhart KP, Metallo SJ. Characterization of the Binding of Small Molecules to Intrinsically Disordered Proteins. Methods in Enzymology. 611: 677-702. PMID 30471704 DOI: 10.1016/Bs.Mie.2018.09.033  0.756
2018 Tsafou K, Tiwari PB, Forman-Kay JD, Metallo SJ, Toretsky JA. Targeting intrinsically disordered transcription factors: Changing the paradigm. Journal of Molecular Biology. PMID 29655986 DOI: 10.1016/J.Jmb.2018.04.008  0.403
2015 Gerhart KP, Metallo SJ. Interaction of the Intrinsically Disordered c-Myc Oncoprotein with Racemic and Enantiopure Small Molecules Biophysical Journal. 108: 389a. DOI: 10.1016/J.Bpj.2014.11.2131  0.841
2015 Fred LM, Gerhart KP, Zablotsky BL, Barnett SA, Metallo SJ. Primary Sequence Controls the Specificity and Affinity of a Small Molecule Binding to the Intrinsically Disordered Protein c-Myc Biophysical Journal. 108: 389a. DOI: 10.1016/J.Bpj.2014.11.2130  0.807
2014 Uversky VN, Davé V, Iakoucheva LM, Malaney P, Metallo SJ, Pathak RR, Joerger AC. Pathological unfoldomics of uncontrolled chaos: Intrinsically disordered proteins and human diseases Chemical Reviews. 114: 6844-6879. PMID 24830552 DOI: 10.1021/Cr400713R  0.436
2014 Gerhart KP, Metallo SJ. Enantiospecific Recognition of the Intrinsically Disordered C-Myc Oncoprotein by Small Molecules Biophysical Journal. 106: 687a. DOI: 10.1016/J.Bpj.2013.11.3803  0.859
2013 Guo J, Clausen DM, Prochownik EV, Metallo SJ, Parise RA, Beumer JH, Eiseman JL. Abstract 1019: Cytotoxicityin vitro, pharmacokinetics and tissue distribution of Link-N3 and Link-F3, two bivalent small molecules inhibitors of c-Myc/Max interactions in C.B-17 SCID mice bearing Daudi Burkitt's lymphoma xenografts. Cancer Research. 73: 1019-1019. DOI: 10.1158/1538-7445.Am2013-1019  0.337
2013 Fred LM, Gerhart KP, Zablotsky BL, Barnett SA, Metallo SJ. Hydrophobic and Hydrophilic Residues are Important for Small Molecule Binding to the Intrinsically Disordered Protein c-Myc Biophysical Journal. 104: 52a-53a. DOI: 10.1016/J.Bpj.2012.11.332  0.814
2012 Barber-Rotenberg JS, Selvanathan SP, Kong Y, Erkizan HV, Snyder TM, Hong SP, Kobs CL, South NL, Summer S, Monroe PJ, Chruszcz M, Dobrev V, Tosso PN, Scher LJ, Minor W, ... ... Metallo SJ, et al. Single enantiomer of YK-4-279 demonstrates specificity in targeting the oncogene EWS-FLI1. Oncotarget. 3: 172-82. PMID 22383402 DOI: 10.18632/Oncotarget.454  0.807
2011 Fred LM, Zablotsky BL, Gerhart KP, Metallo SJ. Alanine Scan of a Small Molecule Interaction Site on the Disordered c-Myc Oncoprotein Biophysical Journal. 100: 61a. DOI: 10.1016/J.Bpj.2010.12.532  0.8
2010 Reed AM, Metallo SJ. Oriented protein adsorption to gold nanoparticles through a genetically encodable binding motif. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 18945-50. PMID 21114269 DOI: 10.1021/la1035135  0.621
2010 Metallo SJ. Intrinsically disordered proteins are potential drug targets. Current Opinion in Chemical Biology. 14: 481-8. PMID 20598937 DOI: 10.1016/J.Cbpa.2010.06.169  0.514
2010 Metallo SJ, Follis AV, Hammoudeh DI, Prochownik E. Mechanism of Small-Molecule Binding by Intrinsically Disordered Proteins Biophysical Journal. 98: 259a. DOI: 10.1016/J.Bpj.2009.12.1410  0.854
2009 Hammoudeh DI, Follis AV, Prochownik EV, Metallo SJ. Multiple independent binding sites for small-molecule inhibitors on the oncoprotein c-Myc. Journal of the American Chemical Society. 131: 7390-401. PMID 19432426 DOI: 10.1021/Ja900616B  0.865
2009 Mustata G, Follis AV, Hammoudeh DI, Metallo SJ, Wang H, Prochownik EV, Lazo JS, Bahar I. Discovery of novel Myc-Max heterodimer disruptors with a three-dimensional pharmacophore model. Journal of Medicinal Chemistry. 52: 1247-50. PMID 19215087 DOI: 10.1021/Jm801278G  0.784
2009 Follis AV, Hammoudeh DI, Daab AT, Metallo SJ. Small-molecule perturbation of competing interactions between c-Myc and Max. Bioorganic & Medicinal Chemistry Letters. 19: 807-10. PMID 19114306 DOI: 10.1016/J.Bmcl.2008.12.025  0.837
2009 Follis AV, Hammoudeh D, Wang H, Prochownik EV, Metallo SJ. Potent Inhibitors Of c-Myc-Max Dimerization Through Multivalent Binding To The Intrinsically Disordered c-Myc Monomer Biophysical Journal. 96: 443a. DOI: 10.1016/J.Bpj.2008.12.2273  0.851
2009 Obando S, Small JL, MacKay CR, Nellis ED, Vivar KL, Metallo SJ. Macrosolute Effects on Nucleic Acid Interactions Biophysical Journal. 96: 347a. DOI: 10.1016/J.Bpj.2008.12.1745  0.764
2009 Hammoudeh D, Viachava-Follis A, Prochownik EV, Metallo SJ. Small Molecule Binding of Intrinsically Disordered Proteins: Multiple Binders on Multiple Sites Biophysical Journal. 96: 319a. DOI: 10.1016/J.Bpj.2008.12.1597  0.847
2008 Follis AV, Hammoudeh DI, Wang H, Prochownik EV, Metallo SJ. Structural rationale for the coupled binding and unfolding of the c-Myc oncoprotein by small molecules. Chemistry & Biology. 15: 1149-55. PMID 19022175 DOI: 10.1016/J.Chembiol.2008.09.011  0.865
2007 Wang H, Hammoudeh DI, Follis AV, Reese BE, Lazo JS, Metallo SJ, Prochownik EV. Improved low molecular weight Myc-Max inhibitors. Molecular Cancer Therapeutics. 6: 2399-408. PMID 17876039 DOI: 10.1158/1535-7163.Mct-07-0005  0.804
2006 Krishnamurthy VM, Quinton LJ, Estroff LA, Metallo SJ, Isaacs JM, Mizgerd JP, Whitesides GM. Promotion of opsonization by antibodies and phagocytosis of Gram-positive bacteria by a bifunctional polyacrylamide. Biomaterials. 27: 3663-74. PMID 16527349 DOI: 10.1016/J.Biomaterials.2006.02.006  0.758
2003 Metallo SJ, Kane RS, Holmlin RE, Whitesides GM. Using bifunctional polymers presenting vancomycin and fluorescein groups to direct anti-fluorescein antibodies to self-assembled monolayers presenting d-alanine-d-alanine groups. Journal of the American Chemical Society. 125: 4534-40. PMID 12683824 DOI: 10.1021/ja030045a  0.541
2003 Stroock AD, Kane RS, Weck M, Metallo SJ, Whitesides GM. Synthesis of free-standing quasi-two-dimensional polymers Langmuir. 19: 2466-2472. DOI: 10.1021/La026379F  0.658
2002 McDonald JC, Chabinyc ML, Metallo SJ, Anderson JR, Stroock AD, Whitesides GM. Prototyping of microfluidic devices in poly(dimethylsiloxane) using solid-object printing. Analytical Chemistry. 74: 1537-45. PMID 12033242 DOI: 10.1021/Ac010938Q  0.725
2002 Qian X, Metallo SJ, Choi IS, Wu H, Liang MN, Whitesides GM. Arrays of self-assembled monolayers for studying inhibition of bacterial adhesion. Analytical Chemistry. 74: 1805-10. PMID 11985311 DOI: 10.1021/Ac011042O  0.645
2001 McDonald JC, Metallo SJ, Whitesides GM. Fabrication of a configurable, single-use microfluidic device. Analytical Chemistry. 73: 5645-50. PMID 11774902 DOI: 10.1021/ac010631r  0.381
2001 Mourez M, Kane RS, Mogridge J, Metallo S, Deschatelets P, Sellman BR, Whitesides GM, Collier RJ. Designing a polyvalent inhibitor of anthrax toxin. Nature Biotechnology. 19: 958-61. PMID 11581662 DOI: 10.1038/Nbt1001-958  0.687
2000 Liang MN, Smith SP, Metallo SJ, Choi IS, Prentiss M, Whitesides GM. Measuring the forces involved in polyvalent adhesion of uropathogenic Escherichia coli to mannose-presenting surfaces. Proceedings of the National Academy of Sciences of the United States of America. 97: 13092-6. PMID 11078520 DOI: 10.1073/Pnas.230451697  0.504
1999 Kohler JJ, Metallo SJ, Schneider TL, Schepartz A. DNA specificity enhanced by sequential binding of protein monomers. Proceedings of the National Academy of Sciences of the United States of America. 96: 11735-9. PMID 10518519 DOI: 10.1073/Pnas.96.21.11735  0.807
1997 Metallo SJ, Paolella DN, Schepartz A. The role of a basic amino acid cluster in target site selection and non-specific binding of bZIP peptides to DNA. Nucleic Acids Research. 25: 2967-72. PMID 9224594 DOI: 10.1093/Nar/25.15.2967  0.557
1997 Metallo SJ, Schepartz A. Certain bZIP peptides bind DNA sequentially as monomers and dimerize on the DNA. Nature Structural Biology. 4: 115-7. PMID 9033590 DOI: 10.1038/Nsb0297-115  0.57
1995 Metallo SJ, Schepartz A. Peptide models of bZIP proteins: Quantitative analysis of DNA affinity and specificity Techniques in Protein Chemistry. 6: 385-391. DOI: 10.1016/S1080-8914(06)80047-5  0.539
1994 Metallo SJ, Schepartz A. Distribution of labor among bZIP segments in the control of DNA affinity and specificity. Chemistry & Biology. 1: 143-51. PMID 9383384 DOI: 10.1016/1074-5521(94)90004-3  0.602
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