Gyanu Lamichhane, PhD - Publications

Affiliations: 
Medicine Johns Hopkins University, Baltimore, MD 
Area:
Tuberculosis Research
Website:
http://www.hopkinsmedicine.org/DOM/TB_Lab/faculty/lamichhane.html

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wazahat R, Juneja P, Chauhan V, Zaidi R, Lamichhane G, Singh UB, Haider M, Kumar P. A strip-based assay for detection of CrfA enzyme activity to differentiate Mycobacterium tuberculosis and non-tuberculous mycobacteria. Journal of Microbiological Methods. 211: 106781. PMID 37437716 DOI: 10.1016/j.mimet.2023.106781  0.643
2022 Ahmad N, Dugad S, Chauhan V, Ahmed S, Sharma K, Kachhap S, Zaidi R, Bishai WR, Lamichhane G, Kumar P. Allosteric cooperation in ß-lactam binding to a non-classical transpeptidase. Elife. 11. PMID 35475970 DOI: 10.7554/eLife.73055  0.672
2022 Galanis C, Maggioncalda EC, Kumar P, Lamichhane G. Glby, Encoded by , Is Required for Growth of Mycobacteroides abscessus and Exhibits Mild β-Lactamase Activity. Journal of Bacteriology. e0004622. PMID 35380462 DOI: 10.1128/jb.00046-22  0.527
2022 De Jager V, Gupte N, Nunes S, Barnes GL, van Wijk RC, Mostert J, Dorman SE, Abulfathi AA, Upton CM, Faraj A, Nuermberger EL, Lamichhane G, Svensson EM, Simonsson U, Diacon AH, et al. Early Bactericidal Activity of Meropenem Plus Clavulanate (+/-Rifampin) For TB: The COMRADE Randomized, Phase 2 Trial. American Journal of Respiratory and Critical Care Medicine. PMID 35258443 DOI: 10.1164/rccm.202108-1976OC  0.322
2022 Kumar G, Galanis C, Batchelder HR, Townsend CA, Lamichhane G. Penicillin Binding Proteins and β-Lactamases of Mycobacterium tuberculosis: Reexamination of the Historical Paradigm. Msphere. 7: e0003922. PMID 35196121 DOI: 10.1128/msphere.00039-22  0.394
2022 Nicklas DA, Maggioncalda EC, Story-Roller E, Eichelman B, Tabor C, Serio AW, Keepers TR, Chitra S, Lamichhane G. Potency of Omadacycline against Mycobacteroides abscessus Clinical Isolates and in a Mouse Model of Pulmonary Infection. Antimicrobial Agents and Chemotherapy. 66: e0170421. PMID 34662184 DOI: 10.1128/AAC.01704-21  0.333
2021 Jadhav R, Gallardo-Macias R, Kumar G, Daher SS, Kaushik A, Bigelow KM, Nuermberger EL, Lamichhane G, Freundlich JS. Assessment of carbapenems in a mouse model of Mycobacterium tuberculosis infection. Plos One. 16: e0249841. PMID 33939697 DOI: 10.1371/journal.pone.0249841  0.362
2021 Ntombela T, Seupersad A, Maseko S, Ibeji CU, Tolufashe G, Maphumulo SI, Naicker T, Baijnath S, Maguire GEM, Govender T, Lamichhane G, Honarparvar B, Kruger HG. Mechanistic insight on the inhibition of D, D-carboxypeptidase from by -lactam antibiotics: an ONIOM acylation study. Journal of Biomolecular Structure & Dynamics. 1-11. PMID 33719919 DOI: 10.1080/07391102.2021.1899052  0.467
2020 Batchelder HR, Story-Roller E, Lloyd EP, Kaushik A, Bigelow KM, Maggioncalda EC, Nuermberger EL, Lamichhane G, Townsend CA. Development of a penem antibiotic against Mycobacteroides abscessus. Communications Biology. 3: 741. PMID 33288821 DOI: 10.1038/s42003-020-01475-2  0.311
2020 Maggioncalda EC, Story-Roller E, Mylius J, Illei P, Basaraba RJ, Lamichhane G. A mouse model of pulmonary Mycobacteroides abscessus infection. Scientific Reports. 10: 3690. PMID 32111900 DOI: 10.1038/S41598-020-60452-1  0.402
2019 Singh UB, Das R, Shrestha P, Bala K, Pandey P, Verma SK, Gautam H, Story-Roller E, Lamichhane G, Guleria R. Compromised longevity due to pulmonary disease in lungs scarred by tuberculosis. Access Microbiology. 1: e000003. PMID 32974490 DOI: 10.1099/acmi.0.000003  0.314
2019 Sabe VT, Tolufashe GF, Ibeji CU, Maseko SB, Govender T, Maguire GEM, Lamichhane G, Honarparvar B, Kruger HG. Identification of potent L,D-transpeptidase 5 inhibitors for Mycobacterium tuberculosis as potential anti-TB leads: virtual screening and molecular dynamics simulations. Journal of Molecular Modeling. 25: 328. PMID 31656981 DOI: 10.1007/S00894-019-4196-Z  0.56
2019 Thota N, Makam P, Rajbongshi KK, Nagiah S, Abdul NS, Chuturgoon AA, Kaushik A, Lamichhane G, Somboro AM, Kruger HG, Govender T, Naicker T, Arvidsson PI. -Trifluoromethylthiolated Sulfonimidamides and Sulfoximines: Anti-microbial, Anti-mycobacterial, and Cytotoxic Activity. Acs Medicinal Chemistry Letters. 10: 1457-1461. PMID 31620233 DOI: 10.1021/Acsmedchemlett.9B00285  0.522
2019 Story-Roller E, Maggioncalda EC, Lamichhane G. Synergistic efficacy of β-lactam combinations against pulmonary infection in mice. Antimicrobial Agents and Chemotherapy. PMID 31109979 DOI: 10.1128/Aac.00614-19  0.397
2019 Ibeji CU, Lawal MM, Tolufashe GF, Govender T, Naicker T, Maguire GEM, Lamichhane G, Kruger HG, Honarparvar B. The Driving Force for the Acylation of β-Lactam Antibiotics by L,D-Transpeptidase 2: Quantum Mechanics/Molecular Mechanics (QM/MM) Study. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. PMID 30969480 DOI: 10.1002/Cphc.201900173  0.513
2019 Story-Roller E, Maggioncalda EC, Lamichhane G. Select β-lactam combinations exhibit synergy against . Antimicrobial Agents and Chemotherapy. PMID 30745389 DOI: 10.1128/Aac.02613-18  0.428
2019 Kaushik A, Ammerman NC, Lee J, Martins O, Kreiswirth BN, Lamichhane G, Parrish NM, Nuermberger EL. activity of the new β-lactamase inhibitors relebactam and vaborbactam in combination with β-lactams against complex clinical isolates. Antimicrobial Agents and Chemotherapy. PMID 30642943 DOI: 10.1128/Aac.02623-18  0.343
2019 Tolufashe GF, Sabe VT, Ibeji CU, Lawal MM, Govender T, Maguire GEM, Lamichhane G, Kruger HG, Honarparvar B. Inhibition mechanism of L,D-transpeptidase 5 in presence of the β-lactams using ONIOM method. Journal of Molecular Graphics & Modelling. 87: 204-210. PMID 30554066 DOI: 10.1016/J.Jmgm.2018.11.009  0.669
2018 Ibeji CU, Tolufashe GF, Ntombela T, Govender T, Maguire GEM, Lamichhane G, Kruger HG, Honarparvar B. The catalytic role of water in the binding site of l,d-transpeptidase 2 within acylation mechanism: A QM/MM (ONIOM) modelling. Tuberculosis (Edinburgh, Scotland). 113: 222-230. PMID 30514506 DOI: 10.1016/J.Tube.2018.10.005  0.608
2018 Tolufashe GF, Sabe VT, Ibeji CU, Ntombela T, Govender T, Maguire GEM, Kruger HG, Lamichhane G, Honarparvar B. Structure and function of L,D- and D,D-transpeptidase family enzymes from Mycobacterium tuberculosis. Current Medicinal Chemistry. PMID 30501595 DOI: 10.2174/0929867326666181203150231  0.688
2018 Story-Roller E, Maggioncalda EC, Cohen KA, Lamichhane G. and β-Lactams: Emerging Insights and Potential Opportunities. Frontiers in Microbiology. 9: 2273. PMID 30319581 DOI: 10.3389/Fmicb.2018.02273  0.355
2018 Story-Roller E, Lamichhane G. Have we realized the full potential of β-lactams for treating drug-resistant TB? Iubmb Life. PMID 29934998 DOI: 10.1002/Iub.1875  0.46
2018 Ntombela T, Fakhar Z, Ibeji CU, Govender T, Maguire GEM, Lamichhane G, Kruger HG, Honarparvar B. Molecular insight on the non-covalent interactions between carbapenems and L,D-transpeptidase 2 from Mycobacterium tuberculosis: ONIOM study. Journal of Computer-Aided Molecular Design. PMID 29845435 DOI: 10.1007/S10822-018-0121-2  0.607
2018 Schwartz M, Fisher S, Story-Roller E, Lamichhane G, Parrish N. Activities of Dual Combinations of Antibiotics Against Multidrug-Resistant Nontuberculous Mycobacteria Recovered from Patients with Cystic Fibrosis. Microbial Drug Resistance (Larchmont, N.Y.). PMID 29368988 DOI: 10.1089/Mdr.2017.0286  0.386
2018 Story-Roller E, Lamichhane G. 803. Overcoming β-Lactam Resistance in Mycobacterium abscessus Open Forum Infectious Diseases. 5: S288-S288. DOI: 10.1093/Ofid/Ofy210.810  0.375
2018 Tolufashe GF, Halder AK, Ibeji CU, Lawal MM, Ntombela T, Govender T, Maguire GEM, Lamichhane G, Kruger HG, Honarparvar B. Inhibition of Mycobacterium tuberculosis L,D-Transpeptidase 5 by Carbapenems: MD and QM/MM Mechanistic Studies Chemistryselect. 3: 13603-13612. DOI: 10.1002/slct.201803184  0.589
2017 Kumar P, Chauhan V, Silva JRA, Lameira J, d'Andrea F, Li S, Ginell SL, Freundlich JS, Alves CN, Bailey S, Cohen KA, Lamichhane G. Mycobacterium abscessus L,D-transpeptidases are susceptible to inactivation by carbapenems and cephalosporins but not penicillins. Antimicrobial Agents and Chemotherapy. PMID 28760902 DOI: 10.1128/Aac.00866-17  0.65
2017 Azzali E, Machado D, Kaushik A, Vacondio F, Flisi S, Cabassi CS, Lamichhane G, Viveiros M, Costantino G, Pieroni M. Substituted N-phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery. Journal of Medicinal Chemistry. PMID 28749666 DOI: 10.1021/Acs.Jmedchem.7B00793  0.438
2017 Kaushik A, Ammerman NC, Tasneen R, Story-Roller E, Dooley KE, Dorman SE, Nuermberger EL, Lamichhane G. In vitro and in vivo activity of biapenem against drug-susceptible and rifampicin-resistant Mycobacterium tuberculosis. The Journal of Antimicrobial Chemotherapy. PMID 28575382 DOI: 10.1093/Jac/Dkx152  0.523
2017 Mattoo R, Lloyd EP, Kaushik A, Kumar P, Brunelle JL, Townsend CA, Lamichhane G. LdtMav2, a nonclassical transpeptidase and susceptibility of Mycobacterium avium to carbapenems. Future Microbiology. PMID 28555497 DOI: 10.2217/Fmb-2016-0208  0.627
2017 Bianchet MA, Pan YH, Basta LAB, Saavedra H, Lloyd EP, Kumar P, Mattoo R, Townsend CA, Lamichhane G. Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem. Bmc Biochemistry. 18: 8. PMID 28545389 DOI: 10.1186/S12858-017-0082-4  0.722
2017 Fakhar Z, Govender T, Maguire GEM, Lamichhane G, Walker RC, Kruger HG, Honarparvar B. Differential flap dynamics in l,d-transpeptidase2 from mycobacterium tuberculosis revealed by molecular dynamics. Molecular Biosystems. PMID 28480928 DOI: 10.1039/C7Mb00110J  0.595
2017 Njire M, Wang N, Wang B, Tan Y, Cai X, Liu Y, Mugweru J, Guo J, Hameed HMA, Tan S, Liu J, Yew WW, Nuermberger E, Lamichhane G, Liu J, et al. Pyrazinoic Acid Inhibits a Bifunctional Enzyme in Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. PMID 28438933 DOI: 10.1128/Aac.00070-17  0.536
2017 Kaushik A, Gupta C, Fisher S, Story-Roller E, Galanis C, Parrish N, Lamichhane G. Combinations of avibactam and carbapenems exhibit enhanced potencies against drug-resistant Mycobacterium abscessus. Future Microbiology. PMID 28326811 DOI: 10.2217/Fmb-2016-0234  0.379
2017 Dey RJ, Dey B, Zheng Y, Cheung LS, Zhou J, Sayre D, Kumar P, Guo H, Lamichhane G, Sintim HO, Bishai WR. Inhibition of innate immune cytosolic surveillance by an M. tuberculosis phosphodiesterase. Nature Chemical Biology. 13: 210-217. PMID 28106876 DOI: 10.1038/Nchembio.2254  0.781
2017 Kumar P, Kaushik A, Bell D, Chauhan V, Xia F, Stevens RL, Lamichhane G. Mutation in an unannotated protein confers carbapenem resistance in Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. PMID 28069655 DOI: 10.1128/Aac.02234-16  0.638
2017 Fakhar Z, Govender T, Lamichhane G, Maguire GE, Kruger HG, Honarparvar B. Computational model for the acylation step of the β-lactam ring: Potential application for l,d-transpeptidase 2 in mycobacterium tuberculosis Journal of Molecular Structure. 1128: 94-102. DOI: 10.1016/J.Molstruc.2016.08.049  0.613
2016 Islam MM, Hameed HM, Mugweru J, Chhotaray C, Wang C, Tan Y, Liu J, Li X, Tan S, Ojima I, Yew WW, Nuermberger E, Lamichhane G, Zhang T. Drug resistance mechanisms and novel drug targets for tuberculosis therapy. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 28117224 DOI: 10.1016/J.Jgg.2016.10.002  0.465
2016 Kumar P, Kaushik A, Lloyd EP, Li SG, Mattoo R, Ammerman NC, Bell DT, Perryman AL, Zandi TA, Ekins S, Ginell SL, Townsend CA, Freundlich JS, Lamichhane G. Non-classical transpeptidases yield insight into new antibacterials. Nature Chemical Biology. PMID 27820797 DOI: 10.1038/Nchembio.2237  0.611
2016 Jaganath D, Lamichhane G, Shah M. Carbapenems against Mycobacterium tuberculosis: a review of the evidence. The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease. 20: 1436-1447. PMID 27776583 DOI: 10.5588/Ijtld.16.0498  0.582
2016 Pelly S, Winglee K, Xia F, Stevens RL, Bishai WR, Lamichhane G. REMap: Operon map of M. tuberculosis based on RNA sequence data. Tuberculosis (Edinburgh, Scotland). 99: 70-80. PMID 27450008 DOI: 10.1016/J.Tube.2016.04.010  0.646
2016 Kaushik A, Heuer AM, Bell DT, Culhane JC, Ebner DC, Parrish N, Ippoliti JT, Lamichhane G. An evolved oxazolidinone with selective potency against Mycobacterium tuberculosis and gram positive bacteria. Bioorganic & Medicinal Chemistry Letters. PMID 27329794 DOI: 10.1016/J.Bmcl.2016.06.019  0.45
2016 Makafe GG, Cao Y, Tan Y, Julius M, Liu Z, Wang C, Njire MM, Cai X, Liu T, Wang B, Pang W, Tan S, Zhang B, Yew WW, Lamichhane G, et al. Oxazolidinone Resistance in Mycobacterium tuberculosis: What is the Role of Cys154Arg Mutation in the Ribosomal Protein L3? Antimicrobial Agents and Chemotherapy. PMID 26953211 DOI: 10.1128/Aac.00152-16  0.429
2016 Pelly S, Winglee K, Xia F, Stevens RL, Bishai WR, Lamichhane G. REMap: Operon map of M. tuberculosis based on RNA sequence data Tuberculosis. 99: 70-80. DOI: 10.1016/j.tube.2016.04.010  0.617
2015 Fakhar Z, Naiker S, Alvez CN, Govender T, Maguire GE, Lameira J, Lamichhane G, Kruger HG, Honarparvar B. A Comparative Modeling and Molecular Docking Study on Mycobacterium Tuberculosis Targets Involved in Peptidoglycan Biosynthesis. Journal of Biomolecular Structure & Dynamics. 1-42. PMID 26612108 DOI: 10.1080/07391102.2015.1117397  0.653
2015 Brammer Basta LA, Ghosh A, Pan Y, Jean J, Lloyd EP, Townsend CA, Lamichhane G, Bianchet MA. Loss of a functionally and structurally distinct L,D-transpeptidase, LdtMt5, compromises cell wall integrity in Mycobacterium tuberculosis. The Journal of Biological Chemistry. PMID 26304120 DOI: 10.1074/Jbc.M115.660753  0.528
2015 Kaushik A, Makkar N, Pandey P, Parrish N, Singh U, Lamichhane G. Carbapenems and Rifampin Exhibit Synergy against Mycobacterium tuberculosis and Mycobacterium abscessus. Antimicrobial Agents and Chemotherapy. 59: 6561-7. PMID 26259792 DOI: 10.1128/Aac.01158-15  0.515
2015 Alyahya SA, Nolan ST, Smith CM, Bishai WR, Sadoff J, Lamichhane G. Immunogenicity without Efficacy of an Adenoviral Tuberculosis Vaccine in a Stringent Mouse Model for Immunotherapy during Treatment. Plos One. 10: e0127907. PMID 25996375 DOI: 10.1371/Journal.Pone.0127907  0.675
2015 Silva JR, Bishai WR, Govender T, Lamichhane G, Maguire GE, Kruger HG, Lameira J, Alves CN. Targeting the cell wall of Mycobacterium tuberculosis: a molecular modeling investigation of the interaction of imipenem and meropenem with L,D-transpeptidase 2. Journal of Biomolecular Structure & Dynamics. 1-14. PMID 25762064 DOI: 10.1080/07391102.2015.1029000  0.72
2015 Moraes GL, Gomes GC, Monteiro de Sousa PR, Alves CN, Govender T, Kruger HG, Maguire GE, Lamichhane G, Lameira J. Structural and functional features of enzymes of Mycobacterium tuberculosis peptidoglycan biosynthesis as targets for drug development. Tuberculosis (Edinburgh, Scotland). 95: 95-111. PMID 25701501 DOI: 10.1016/J.Tube.2015.01.006  0.699
2014 Dutta NK, Bandyopadhyay N, Veeramani B, Lamichhane G, Karakousis PC, Bader JS. Systems biology-based identification of Mycobacterium tuberculosis persistence genes in mouse lungs. Mbio. 5. PMID 24549847 DOI: 10.1128/Mbio.01066-13  0.556
2014 Schoonmaker MK, Bishai WR, Lamichhane G. Nonclassical transpeptidases of Mycobacterium tuberculosis alter cell size, morphology, the cytosolic matrix, protein localization, virulence, and resistance to β-lactams. Journal of Bacteriology. 196: 1394-402. PMID 24464457 DOI: 10.1128/Jb.01396-13  0.751
2012 Erdemli SB, Gupta R, Bishai WR, Lamichhane G, Amzel LM, Bianchet MA. Targeting the cell wall of Mycobacterium tuberculosis: structure and mechanism of L,D-transpeptidase 2. Structure (London, England : 1993). 20: 2103-15. PMID 23103390 DOI: 10.1016/J.Str.2012.09.016  0.717
2012 Sarker M, Talcott C, Madrid P, Chopra S, Bunin BA, Lamichhane G, Freundlich JS, Ekins S. Combining cheminformatics methods and pathway analysis to identify molecules with whole-cell activity against Mycobacterium tuberculosis. Pharmaceutical Research. 29: 2115-27. PMID 22477069 DOI: 10.1007/S11095-012-0741-5  0.486
2012 Pelly S, Bishai WR, Lamichhane G. A screen for non-coding RNA in Mycobacterium tuberculosis reveals a cAMP-responsive RNA that is expressed during infection. Gene. 500: 85-92. PMID 22446041 DOI: 10.1016/J.Gene.2012.03.044  0.695
2011 Lamichhane G. Mycobacterium tuberculosis response to stress from reactive oxygen and nitrogen species. Frontiers in Microbiology. 2: 176. PMID 21904537 DOI: 10.3389/Fmicb.2011.00176  0.392
2011 Lamichhane G, Freundlich JS, Ekins S, Wickramaratne N, Nolan ST, Bishai WR. Essential metabolites of Mycobacterium tuberculosis and their mimics. Mbio. 2: e00301-10. PMID 21285434 DOI: 10.1128/Mbio.00301-10  0.717
2011 Wolschendorf F, Ackart D, Shrestha TB, Hascall-Dove L, Nolan S, Lamichhane G, Wang Y, Bossmann SH, Basaraba RJ, Niederweis M. Copper resistance is essential for virulence of Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 108: 1621-6. PMID 21205886 DOI: 10.1073/Pnas.1009261108  0.345
2011 Lamichhane G. Novel targets in M. tuberculosis: search for new drugs. Trends in Molecular Medicine. 17: 25-33. PMID 21071272 DOI: 10.1016/J.Molmed.2010.10.004  0.54
2010 Nolan ST, Lamichhane G. Protective efficacy of BCG overexpressing an L,D-transpeptidase against M. tuberculosis infection. Plos One. 5: e13773. PMID 21048936 DOI: 10.1371/Journal.Pone.0013773  0.518
2010 Converse PJ, Eisenach KD, Theus SA, Nuermberger EL, Tyagi S, Ly LH, Geiman DE, Guo H, Nolan ST, Akar NC, Klinkenberg LG, Gupta R, Lun S, Karakousis PC, Lamichhane G, et al. The impact of mouse passaging of Mycobacterium tuberculosis strains prior to virulence testing in the mouse and guinea pig aerosol models. Plos One. 5: e10289. PMID 20422019 DOI: 10.1371/Journal.Pone.0010289  0.713
2010 Dutta NK, Mehra S, Didier PJ, Roy CJ, Doyle LA, Alvarez X, Ratterree M, Be NA, Lamichhane G, Jain SK, Lacey MR, Lackner AA, Kaushal D. Genetic requirements for the survival of tubercle bacilli in primates. The Journal of Infectious Diseases. 201: 1743-52. PMID 20394526 DOI: 10.1086/652497  0.815
2010 Gupta R, Lavollay M, Mainardi JL, Arthur M, Bishai WR, Lamichhane G. The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin. Nature Medicine. 16: 466-9. PMID 20305661 DOI: 10.1038/Nm.2120  0.743
2010 Olaleye O, Raghunand TR, Bhat S, He J, Tyagi S, Lamichhane G, Gu P, Zhou J, Zhang Y, Grosset J, Bishai WR, Liu JO. Methionine aminopeptidases from Mycobacterium tuberculosis as novel antimycobacterial targets. Chemistry & Biology. 17: 86-97. PMID 20142044 DOI: 10.1016/J.Chembiol.2009.12.014  0.745
2009 Davis SL, Be NA, Lamichhane G, Nimmagadda S, Pomper MG, Bishai WR, Jain SK. Bacterial thymidine kinase as a non-invasive imaging reporter for Mycobacterium tuberculosis in live animals. Plos One. 4: e6297. PMID 19606217 DOI: 10.1371/Journal.Pone.0006297  0.813
2009 Agarwal N, Lamichhane G, Gupta R, Nolan S, Bishai WR. Cyclic AMP intoxication of macrophages by a Mycobacterium tuberculosis adenylate cyclase. Nature. 460: 98-102. PMID 19516256 DOI: 10.1038/Nature08123  0.718
2009 Alahari A, Alibaud L, Trivelli X, Gupta R, Lamichhane G, Reynolds RC, Bishai WR, Guerardel Y, Kremer L. Mycolic acid methyltransferase, MmaA4, is necessary for thiacetazone susceptibility in Mycobacterium tuberculosis. Molecular Microbiology. 71: 1263-77. PMID 19183278 DOI: 10.1111/J.1365-2958.2009.06604.X  0.723
2009 Converse PJ, Karakousis PC, Klinkenberg LG, Kesavan AK, Ly LH, Allen SS, Grosset JH, Jain SK, Lamichhane G, Manabe YC, McMurray DN, Nuermberger EL, Bishai WR. Role of the dosR-dosS two-component regulatory system in Mycobacterium tuberculosis virulence in three animal models. Infection and Immunity. 77: 1230-7. PMID 19103767 DOI: 10.1128/Iai.01117-08  0.691
2009 Be NA, Lamichhane G, Grosset J. Murine model to study the invasion and survival of Mycobacterium tuberculosis in the central nervous system. (Journal of Infectious Diseases (2008) 198, (1520-1528)) Journal of Infectious Diseases. 199: 290. DOI: 10.1086/596032  0.765
2008 Be NA, Lamichhane G, Grosset J, Tyagi S, Cheng QJ, Kim KS, Bishai WR, Jain SK. Murine model to study the invasion and survival of Mycobacterium tuberculosis in the central nervous system. The Journal of Infectious Diseases. 198: 1520-8. PMID 18956986 DOI: 10.1086/592447  0.825
2008 Jain SK, Lamichhane G, Nimmagadda S, Pomper MG, Bishai WR. Antibiotic treatment of tuberculosis: Old problems, new solutions Microbe. 3: 285-292. DOI: 10.1128/Microbe.3.285.1  0.705
2007 Jain SK, Hernandez-Abanto SM, Cheng QJ, Singh P, Ly LH, Klinkenberg LG, Morrison NE, Converse PJ, Nuermberger E, Grosset J, McMurray DN, Karakousis PC, Lamichhane G, Bishai WR. Accelerated detection of Mycobacterium tuberculosis genes essential for bacterial survival in guinea pigs, compared with mice. The Journal of Infectious Diseases. 195: 1634-42. PMID 17471433 DOI: 10.1086/517526  0.726
2007 Lamichhane G, Bishai W. Defining the 'survivasome' of Mycobacterium tuberculosis. Nature Medicine. 13: 280-2. PMID 17342137 DOI: 10.1038/Nm0307-280  0.734
2006 Lamichhane G, Raghunand TR, Morrison NE, Woolwine SC, Tyagi S, Kandavelou K, Bishai WR. Deletion of a Mycobacterium tuberculosis proteasomal ATPase homologue gene produces a slow-growing strain that persists in host tissues. The Journal of Infectious Diseases. 194: 1233-40. PMID 17041849 DOI: 10.1086/508288  0.736
2006 Jain SK, Paul-Satyaseela M, Lamichhane G, Kim KS, Bishai WR. Mycobacterium tuberculosis invasion and traversal across an in vitro human blood-brain barrier as a pathogenic mechanism for central nervous system tuberculosis. The Journal of Infectious Diseases. 193: 1287-95. PMID 16586367 DOI: 10.1086/502631  0.744
2005 Lamichhane G, Tyagi S, Bishai WR. Designer arrays for defined mutant analysis to detect genes essential for survival of Mycobacterium tuberculosis in mouse lungs. Infection and Immunity. 73: 2533-40. PMID 15784600 DOI: 10.1128/Iai.73.4.2533-2540.2005  0.703
2004 Karakousis PC, Yoshimatsu T, Lamichhane G, Woolwine SC, Nuermberger EL, Grosset J, Bishai WR. Dormancy phenotype displayed by extracellular Mycobacterium tuberculosis within artificial granulomas in mice. The Journal of Experimental Medicine. 200: 647-57. PMID 15353557 DOI: 10.1084/Jem.20040646  0.741
2004 Yoder MA, Lamichhane G, Bishai WR. Cavitary pulmonary tuberculosis: The Holy Grail of disease transmission Current Science. 86: 74-81.  0.307
2003 Lamichhane G, Zignol M, Blades NJ, Geiman DE, Dougherty A, Grosset J, Broman KW, Bishai WR. A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 100: 7213-8. PMID 12775759 DOI: 10.1073/Pnas.1231432100  0.642
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