Thomas J. Santangelo, Ph.D. - Publications

Affiliations: 
Cornell University, Ithaca, NY, United States 
Area:
DNA transcription by the enzyme RNA polymerase

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wang C, Molodtsov V, Sanders TJ, Marshall CJ, Firlar E, Kaelber JT, Santangelo TJ, Ebright RH. Structural basis of archaeal FttA-dependent transcription termination. Biorxiv : the Preprint Server For Biology. PMID 37609354 DOI: 10.1101/2023.08.09.552649  0.42
2022 Marshall CJ, Qayyum MZ, Walker JE, Murakami KS, Santangelo TJ. The structure and activities of the archaeal transcription termination factor Eta detail vulnerabilities of the transcription elongation complex. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207581119. PMID 35917344 DOI: 10.1073/pnas.2207581119  0.404
2020 Wenck BR, Santangelo TJ. Archaeal transcription. Transcription. 1-12. PMID 33112729 DOI: 10.1080/21541264.2020.1838865  0.313
2020 Sas-Chen A, Thomas JM, Matzov D, Taoka M, Nance KD, Nir R, Bryson KM, Shachar R, Liman GLS, Burkhart BW, Gamage ST, Nobe Y, Briney CA, Levy MJ, Fuchs RT, ... ... Santangelo TJ, et al. Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping. Nature. PMID 32555463 DOI: 10.1038/S41586-020-2418-2  0.329
2020 Sanders TJ, Wenck BR, Selan JN, Barker MP, Trimmer SA, Walker JE, Santangelo TJ. FttA is a CPSF73 homologue that terminates transcription in Archaea. Nature Microbiology. PMID 32094586 DOI: 10.1038/s41564-020-0667-3  0.407
2018 Sanders TJ, Lammers M, Marshall CJ, Walker JE, Lynch ER, Santangelo TJ. TFS and Spt4/5 accelerate transcription through archaeal histone-based chromatin. Molecular Microbiology. PMID 30592095 DOI: 10.1111/mmi.14191  0.37
2017 Walker JE, Luyties O, Santangelo TJ. Factor-dependent archaeal transcription termination. Proceedings of the National Academy of Sciences of the United States of America. PMID 28760969 DOI: 10.1073/pnas.1704028114  0.458
2017 Gehring AM, Santangelo TJ. Archaeal RNA Polymerase Arrests Transcription at DNA Lesions. Transcription. 0. PMID 28598254 DOI: 10.1080/21541264.2017.1324941  0.38
2017 Burkhart BW, Cubonova L, Heider MR, Kelman Z, Reeve JN, Santangelo TJ. The GAN exonuclease, or the flap endonuclease Fen1 and RNase HII are necessary for viability of Thermococcus kodakarensis. Journal of Bacteriology. PMID 28416706 DOI: 10.1128/Jb.00141-17  0.352
2016 Gehring AM, Walker JE, Santangelo TJ. Transcription Regulation in Archaea. Journal of Bacteriology. PMID 27137495 DOI: 10.1128/JB.00255-16  0.325
2015 Walker JE, Santangelo TJ. Analyses of in vivo interactions between transcription factors and the archaeal RNA polymerase. Methods (San Diego, Calif.). PMID 26028597 DOI: 10.1016/j.ymeth.2015.05.023  0.423
2015 Artsimovitch I, Santangelo TJ. Preface. Bacterial transcriptional control. Methods in Molecular Biology (Clifton, N.J.). 1276: v. PMID 25811056 DOI: 10.1007/978-1-4939-2392-2  0.345
2015 Gehring AM, Santangelo TJ. Manipulating archaeal systems to permit analyses of transcription elongation-termination decisions in vitro. Methods in Molecular Biology (Clifton, N.J.). 1276: 263-79. PMID 25665569 DOI: 10.1007/978-1-4939-2392-2_15  0.429
2014 Jun SH, Hirata A, Kanai T, Santangelo TJ, Imanaka T, Murakami KS. The X-ray crystal structure of the euryarchaeal RNA polymerase in an open-clamp configuration. Nature Communications. 5: 5132. PMID 25311937 DOI: 10.1038/ncomms6132  0.341
2014 Jäger D, Förstner KU, Sharma CM, Santangelo TJ, Reeve JN. Primary transcriptome map of the hyperthermophilic archaeon Thermococcus kodakarensis. Bmc Genomics. 15: 684. PMID 25127548 DOI: 10.1186/1471-2164-15-684  0.306
2014 Li Z, Huang RYC, Yopp DC, Hileman TH, Santangelo TJ, Hurwitz J, Hudgens JW, Kelman Z. A novel mechanism for regulating the activity of proliferating cell nuclear antigen by a small protein Nucleic Acids Research. 42: 5776-5789. PMID 24728986 DOI: 10.1093/Nar/Gku239  0.362
2013 Nalabothula N, Xi L, Bhattacharyya S, Widom J, Wang JP, Reeve JN, Santangelo TJ, Fondufe-Mittendorf YN. Archaeal nucleosome positioning in vivo and in vitro is directed by primary sequence motifs. Bmc Genomics. 14: 391. PMID 23758892 DOI: 10.1186/1471-2164-14-391  0.354
2013 Pan M, Santangelo TJ, Čuboňová L, Li Z, Metangmo H, Ladner J, Hurwitz J, Reeve JN, Kelman Z. Thermococcus kodakarensis has two functional PCNA homologs but only one is required for viability Extremophiles. 17: 453-461. PMID 23525944 DOI: 10.1007/S00792-013-0526-8  0.432
2013 Cubonová L, Richardson T, Burkhart BW, Kelman Z, Connolly BA, Reeve JN, Santangelo TJ. Archaeal DNA polymerase D but not DNA polymerase B is required for genome replication in Thermococcus kodakarensis. Journal of Bacteriology. 195: 2322-8. PMID 23504010 DOI: 10.1128/Jb.02037-12  0.38
2012 Čuboňováa L, Katano M, Kanai T, Atomi H, Reeve JN, Santangelo TJ. An archaeal histone is required for transformation of Thermococcus kodakarensis. Journal of Bacteriology. 194: 6864-74. PMID 23065975 DOI: 10.1128/Jb.01523-12  0.384
2012 Raina M, Elgamal S, Santangelo TJ, Ibba M. Association of a multi-synthetase complex with translating ribosomes in the archaeon Thermococcus kodakarensis. Febs Letters. 586: 2232-8. PMID 22683511 DOI: 10.1016/J.Febslet.2012.05.039  0.351
2011 Pan M, Santangelo TJ, Li Z, Reeve JN, Kelman Z. Thermococcus kodakarensis encodes three MCM homologs but only one is essential. Nucleic Acids Research. 39: 9671-80. PMID 21821658 DOI: 10.1093/Nar/Gkr624  0.317
2011 Santangelo TJ, Artsimovitch I. Termination and antitermination: RNA polymerase runs a stop sign. Nature Reviews. Microbiology. 9: 319-29. PMID 21478900 DOI: 10.1038/Nrmicro2560  0.474
2011 Li Z, Pan M, Santangelo TJ, Chemnitz W, Yuan W, Edwards JL, Hurwitz J, Reeve JN, Kelman Z. A novel DNA nuclease is stimulated by association with the GINS complex Nucleic Acids Research. 39: 6114-6123. PMID 21459845 DOI: 10.1093/Nar/Gkr181  0.428
2010 Li Z, Santangelo TJ, Cuboňová L, Reeve JN, Kelman Z. Affinity purification of an archaeal DNA replication protein network. Mbio. 1. PMID 20978540 DOI: 10.1128/Mbio.00221-10  0.361
2010 Santangelo TJ, Reeve JN. Deletion of switch 3 results in an archaeal RNA polymerase that is defective in transcript elongation. The Journal of Biological Chemistry. 285: 23908-15. PMID 20511223 DOI: 10.1074/Jbc.M109.094565  0.538
2009 Santangelo TJ, Cubonová L, Skinner KM, Reeve JN. Archaeal intrinsic transcription termination in vivo. Journal of Bacteriology. 191: 7102-8. PMID 19749050 DOI: 10.1128/Jb.00982-09  0.46
2009 Dev K, Santangelo TJ, Rothenburg S, Neculai D, Dey M, Sicheri F, Dever TE, Reeve JN, Hinnebusch AG. Archaeal aIF2B Interacts with Eukaryotic Translation Initiation Factors eIF2α and eIF2Bα: Implications for aIF2B Function and eIF2B Regulation Journal of Molecular Biology. 392: 701-722. PMID 19616556 DOI: 10.1016/J.Jmb.2009.07.030  0.352
2008 Hirata A, Kanai T, Santangelo TJ, Tajiri M, Manabe K, Reeve JN, Imanaka T, Murakami KS. Archaeal RNA polymerase subunits E and F are not required for transcription in vitro, but a Thermococcus kodakarensis mutant lacking subunit F is temperature-sensitive. Molecular Microbiology. 70: 623-33. PMID 18786148 DOI: 10.1111/J.1365-2958.2008.06430.X  0.401
2008 Santangelo TJ, Cubonová L, Reeve JN. Shuttle vector expression in Thermococcus kodakaraensis: contributions of cis elements to protein synthesis in a hyperthermophilic archaeon. Applied and Environmental Microbiology. 74: 3099-104. PMID 18378640 DOI: 10.1128/Aem.00305-08  0.375
2007 Davydova EK, Santangelo TJ, Rothman-Denes LB. Bacteriophage N4 virion RNA polymerase interaction with its promoter DNA hairpin. Proceedings of the National Academy of Sciences of the United States of America. 104: 7033-8. PMID 17438270 DOI: 10.1073/Pnas.0610627104  0.523
2007 Santangelo TJ, Cubonová L, James CL, Reeve JN. TFB1 or TFB2 is sufficient for Thermococcus kodakaraensis viability and for basal transcription in vitro. Journal of Molecular Biology. 367: 344-57. PMID 17275836 DOI: 10.1016/J.Jmb.2006.12.069  0.426
2007 French SL, Santangelo TJ, Beyer AL, Reeve JN. Transcription and translation are coupled in Archaea. Molecular Biology and Evolution. 24: 893-5. PMID 17237472 DOI: 10.1093/Molbev/Msm007  0.432
2007 Shin JH, Santangelo TJ, Xie Y, Reeve JN, Kelman Z. Archaeal minichromosome maintenance (MCM) helicase can unwind DNA bound by archaeal histones and transcription factors. The Journal of Biological Chemistry. 282: 4908-15. PMID 17158792 DOI: 10.1074/Jbc.M606847200  0.52
2006 Bai L, Santangelo TJ, Wang MD. Single-molecule analysis of RNA polymerase transcription. Annual Review of Biophysics and Biomolecular Structure. 35: 343-60. PMID 16689640 DOI: 10.1146/Annurev.Biophys.35.010406.150153  0.468
2006 Holmes SF, Santangelo TJ, Cunningham CK, Roberts JW, Erie DA. Kinetic investigation of Escherichia coli RNA polymerase mutants that influence nucleotide discrimination and transcription fidelity. The Journal of Biological Chemistry. 281: 18677-83. PMID 16621791 DOI: 10.1074/Jbc.M600543200  0.571
2006 Santangelo TJ, Reeve JN. Archaeal RNA polymerase is sensitive to intrinsic termination directed by transcribed and remote sequences. Journal of Molecular Biology. 355: 196-210. PMID 16305799 DOI: 10.1016/J.Jmb.2005.10.062  0.502
2005 Wickstrum JR, Santangelo TJ, Egan SM. Cyclic AMP receptor protein and RhaR synergistically activate transcription from the L-rhamnose-responsive rhaSR promoter in Escherichia coli. Journal of Bacteriology. 187: 6708-18. PMID 16166533 DOI: 10.1128/Jb.187.19.6708-6718.2005  0.433
2004 Shundrovsky A, Santangelo TJ, Roberts JW, Wang MD. A single-molecule technique to study sequence-dependent transcription pausing. Biophysical Journal. 87: 3945-53. PMID 15465875 DOI: 10.1529/Biophysj.104.044081  0.578
2004 Santangelo TJ, Roberts JW. Forward translocation is the natural pathway of RNA release at an intrinsic terminator. Molecular Cell. 14: 117-26. PMID 15068808 DOI: 10.1016/S1097-2765(04)00154-6  0.625
2003 Santangelo TJ, Roberts JW. Formation of long DNA templates containing site-specific alkane-disulfide DNA interstrand cross-links for use in transcription reactions. Methods in Enzymology. 371: 120-32. PMID 14712695 DOI: 10.1016/S0076-6879(03)71008-8  0.599
2003 Santangelo TJ, Mooney RA, Landick R, Roberts JW. RNA polymerase mutations that impair conversion to a termination-resistant complex by Q antiterminator proteins. Genes & Development. 17: 1281-92. PMID 12756229 DOI: 10.1101/Gad.1082103  0.62
2002 Adelman K, La Porta A, Santangelo TJ, Lis JT, Roberts JW, Wang MD. Single molecule analysis of RNA polymerase elongation reveals uniform kinetic behavior. Proceedings of the National Academy of Sciences of the United States of America. 99: 13538-43. PMID 12370445 DOI: 10.1073/Pnas.212358999  0.603
2002 Santangelo TJ, Roberts JW. RfaH, a bacterial transcription antiterminator. Molecular Cell. 9: 698-700. PMID 11983161 DOI: 10.1016/S1097-2765(02)00516-6  0.658
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