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Andrei V. Karginov, Ph.D. - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Signal transduction
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Fauser J, Huyot V, Matsche J, Szynal BN, Alexeev Y, Kota P, Karginov AV. Dissecting protein tyrosine phosphatase signaling by engineered chemogenetic control of its activity. The Journal of Cell Biology. 221. PMID 35829702 DOI: 10.1083/jcb.202111066  0.33
2022 Pham H, Hoseini Soflaee M, Karginov AV, Miller LW. Förster resonance energy transfer biosensors for fluorescence and time-gated luminescence analysis of rac1 activity. Scientific Reports. 12: 5291. PMID 35351946 DOI: 10.1038/s41598-022-09364-w  0.309
2021 Chadelle L, Liu J, Choesmel-Cadamuro V, Karginov AV, Froment C, Burlet-Schiltz O, Gandarillas S, Barreira Y, Segura C, Van Den Berghe L, Czaplicki G, Van Acker N, Dalenc F, Franchet C, Hahn KM, et al. PKCθ-mediated serine/threonine phosphorylations of FAK govern adhesion and protrusion dynamics within the lamellipodia of migrating breast cancer cells. Cancer Letters. PMID 34826547 DOI: 10.1016/j.canlet.2021.11.026  0.392
2020 Shaaya M, Fauser J, Zhurikhina A, Conage-Pough JE, Huyot V, Brennan M, Flower CT, Matsche J, Khan S, Natarajan V, Rehman J, Kota P, White FM, Tsygankov D, Karginov AV. Light-Regulated allosteric switch enables temporal and subcellular control of enzyme activity. Elife. 9. PMID 32965214 DOI: 10.7554/eLife.60647  0.332
2020 Collins KB, Kang H, Matsche J, Klomp JE, Rehman J, Malik AB, Karginov AV. Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis. The Journal of Cell Biology. 219. PMID 31865373 DOI: 10.1083/Jcb.201903023  0.341
2019 Klomp JE, Shaaya M, Matsche J, Rebiai R, Aaron JS, Collins KB, Huyot V, Gonzalez AM, Muller WA, Chew TL, Malik AB, Karginov AV. Time-Variant SRC Kinase Activation Determines Endothelial Permeability Response. Cell Chemical Biology. PMID 31130521 DOI: 10.1016/J.Chembiol.2019.04.007  0.319
2017 Ray AM, Klomp JE, Collins KB, Karginov AV. Dissecting Kinase Effector Signaling Using the RapRTAP Methodology. Methods in Molecular Biology (Clifton, N.J.). 1636: 21-33. PMID 28730470 DOI: 10.1007/978-1-4939-7154-1_2  0.443
2017 Dagliyan O, Karginov AV, Yagishita S, Gale ME, Wang H, DerMardirossian C, Wells CM, Dokholyan NV, Kasai H, Hahn KM. Engineering Pak1 allosteric switches. Acs Synthetic Biology. PMID 28365983 DOI: 10.1021/Acssynbio.6B00359  0.357
2016 Klomp JE, Huyot V, Ray AM, Collins KB, Malik AB, Karginov AV. Mimicking transient activation of protein kinases in living cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27956599 DOI: 10.1073/pnas.1609675114  0.386
2016 Zimnicka AM, Husain YS, Shajahan AN, Sverdlov M, Chaga O, Chen Z, Toth PT, Klomp J, Karginov AV, Tiruppathi C, Malik AB, Minshall RD. Src-dependent phosphorylation of caveolin-1 Tyr14 promotes swelling and release of caveolae. Molecular Biology of the Cell. PMID 27170175 DOI: 10.1091/Mbc.E15-11-0756  0.41
2016 Gentry LR, Karginov AV, Hahn KM, Der CJ. Characterization of an Engineered Src Kinase to Study Src Signaling and Biology. Methods in Molecular Biology (Clifton, N.J.). 1360: 157-67. PMID 26501909 DOI: 10.1007/978-1-4939-3073-9_12  0.367
2015 Shen B, Estevez B, Xu Z, Kreutz B, Karginov A, Bai Y, Qian F, Norifumi U, Mosher D, Du X. The interaction of Gα13 with integrin β1 mediates cell migration by dynamic regulation of RhoA. Molecular Biology of the Cell. PMID 26310447 DOI: 10.1091/Mbc.E15-05-0274  0.315
2015 Wang L, Burmeister BT, Johnson KR, Baillie GS, Karginov AV, Skidgel RA, O'Bryan JP, Carnegie GK. UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy. Cellular Signalling. 27: 908-22. PMID 25683917 DOI: 10.1016/j.cellsig.2015.02.003  0.33
2014 Chu PH, Tsygankov D, Berginski ME, Dagliyan O, Gomez SM, Elston TC, Karginov AV, Hahn KM. Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms. Proceedings of the National Academy of Sciences of the United States of America. 111: 12420-5. PMID 25118278 DOI: 10.1073/Pnas.1404487111  0.426
2014 Karginov AV, Hahn KM, Deiters A. Optochemical activation of kinase function in live cells. Methods in Molecular Biology (Clifton, N.J.). 1148: 31-43. PMID 24718793 DOI: 10.1007/978-1-4939-0470-9_3  0.351
2014 Karginov AV, Tsygankov D, Berginski M, Chu PH, Trudeau ED, Yi JJ, Gomez S, Elston TC, Hahn KM. Dissecting motility signaling through activation of specific Src-effector complexes. Nature Chemical Biology. 10: 286-90. PMID 24609359 DOI: 10.1038/Nchembio.1477  0.455
2014 Patel M, Karginov AV. Phosphorylation-mediated regulation of GEFs for RhoA. Cell Adhesion & Migration. 8: 11-8. PMID 24589508 DOI: 10.4161/cam.28058  0.405
2013 Dagliyan O, Shirvanyants D, Karginov AV, Ding F, Fee L, Chandrasekaran SN, Freisinger CM, Smolen GA, Huttenlocher A, Hahn KM, Dokholyan NV. Rational design of a ligand-controlled protein conformational switch. Proceedings of the National Academy of Sciences of the United States of America. 110: 6800-4. PMID 23569285 DOI: 10.1073/Pnas.1218319110  0.415
2013 Chu P, Karginov AV, Tsygankov DM, Berginski ME, Gomez SM, Elston TC, Hahn KM. New Tools for Activation of Src Family Isoforms In Vivo Demonstrate Specific Roles for Each Isoform in Cell Motility Biophysical Journal. 104: 161a. DOI: 10.1016/J.Bpj.2012.11.907  0.463
2013 Karginov AV, Tsygangov D, Berginski ME, Trudeau ED, Chu P, Yi JJ, Gomez SM, Elston TC, Hahn KM. Engineered Manipulation of Signaling Networks: Control of Kinase Activation and Interactions Dissects Parallel Src Pathways Biophysical Journal. 104: 161a. DOI: 10.1016/J.Bpj.2012.11.906  0.484
2013 Chu P, Karginov AV, Shirvanyants DG, Dokholyan NV, Hahn KM. Generation of a Light Inhibited Src Kinase through Insertion of LOV into the Catalytic Domain Biophysical Journal. 104: 679a. DOI: 10.1016/J.Bpj.2012.11.3750  0.387
2011 Karginov AV, Hahn KM. Allosteric activation of kinases: design and application of RapR kinases. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 14.13.. PMID 22161545 DOI: 10.1002/0471143030.Cb1413S53  0.381
2011 Karginov AV, Zou Y, Shirvanyants D, Kota P, Dokholyan NV, Young DD, Hahn KM, Deiters A. Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP. Journal of the American Chemical Society. 133: 420-3. PMID 21162531 DOI: 10.1021/Ja109630V  0.431
2010 Karginov AV, Ding F, Kota P, Dokholyan NV, Hahn KM. Engineered allosteric activation of kinases in living cells. Nature Biotechnology. 28: 743-7. PMID 20581846 DOI: 10.1038/Nbt.1639  0.476
2008 Cai X, Lietha D, Ceccarelli DF, Karginov AV, Rajfur Z, Jacobson K, Hahn KM, Eck MJ, Schaller MD. Spatial and temporal regulation of focal adhesion kinase activity in living cells. Molecular and Cellular Biology. 28: 201-14. PMID 17967873 DOI: 10.1128/Mcb.01324-07  0.581
2004 Bougnères L, Girardin SE, Weed SA, Karginov AV, Olivo-Marin JC, Parsons JT, Sansonetti PJ, Van Nhieu GT. Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells. The Journal of Cell Biology. 166: 225-35. PMID 15263018 DOI: 10.1083/Jcb.200402073  0.655
2003 Kinley AW, Weed SA, Weaver AM, Karginov AV, Bissonette E, Cooper JA, Parsons JT. Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion. Current Biology : Cb. 13: 384-93. PMID 12620186 DOI: 10.1016/S0960-9822(03)00107-6  0.658
2002 Schafer DA, Weed SA, Binns D, Karginov AV, Parsons JT, Cooper JA. Dynamin2 and cortactin regulate actin assembly and filament organization. Current Biology : Cb. 12: 1852-7. PMID 12419186 DOI: 10.1016/S0960-9822(02)01228-9  0.637
2002 Weaver AM, Heuser JE, Karginov AV, Lee WL, Parsons JT, Cooper JA. Interaction of cortactin and N-WASp with Arp2/3 complex. Current Biology : Cb. 12: 1270-8. PMID 12176354 DOI: 10.1016/S0960-9822(02)01035-7  0.593
2002 Liu Y, Loijens JC, Martin KH, Karginov AV, Parsons JT. The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly. Molecular Biology of the Cell. 13: 2147-56. PMID 12058076 DOI: 10.1091/Mbc.E02-01-0018  0.594
2001 Weaver AM, Karginov AV, Kinley AW, Weed SA, Li Y, Parsons JT, Cooper JA. Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation. Current Biology : Cb. 11: 370-4. PMID 11267876 DOI: 10.1016/S0960-9822(01)00098-7  0.616
2000 Weed SA, Karginov AV, Schafer DA, Weaver AM, Kinley AW, Cooper JA, Parsons JT. Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex. The Journal of Cell Biology. 151: 29-40. PMID 11018051 DOI: 10.1083/Jcb.151.1.29  0.646
1999 Eto M, Karginov A, Brautigan DL. A novel phosphoprotein inhibitor of protein type-1 phosphatase holoenzymes. Biochemistry. 38: 16952-7. PMID 10606530 DOI: 10.1021/Bi992030O  0.416
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