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Sahar Nissim, Ph.D. - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
genetics, morphogenesis, limb, evolution
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Tzouanas CN, Sherman MS, Shay JES, Rubin AJ, Mead BE, Dao TT, Butzlaff T, Mana MD, Kolb KE, Walesky C, Pepe-Mooney BJ, Smith CJ, Prakadan SM, Ramseier ML, Tong EY, ... ... Nissim S, et al. Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival. Biorxiv : the Preprint Server For Biology. PMID 38077056 DOI: 10.1101/2023.11.30.569407  0.659
2022 Chittenden A, Haraldsdottir S, Chen E, Nissim S. Germline Testing for Individuals with Pancreatic Adenocarcinoma and Novel Genetic Risk Factors. Hematology/Oncology Clinics of North America. 36: 943-960. PMID 36265992 DOI: 10.1016/j.hoc.2022.07.008  0.691
2021 Aney KJ, Nissim S. More than acinar identity? A novel cystic phenotype suggests broader roles for NR5A2 in pancreatic cancer†. The Journal of Pathology. PMID 33448017 DOI: 10.1002/path.5619  0.721
2019 Nissim S, Leshchiner I, Mancias JD, Greenblatt MB, Maertens O, Cassa CA, Rosenfeld JA, Cox AG, Hedgepeth J, Wucherpfennig JI, Kim AJ, Henderson JE, Gonyo P, Brandt A, Lorimer E, et al. Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer. Nature Genetics. PMID 31406347 DOI: 10.1038/S41588-019-0475-Y  0.574
2017 Nissim S, Leshchiner I, Mancias JD, Greenblatt MB, Maertens O, Cassa CA, Rosenfeld JA, Cox AG, Hedgepeth J, Wücherpfennig J, Kim AJ, Henderson JE, Gonyo P, Brandt A, Lorimer E, et al. Abstract 4272: Mutations inRABL3alter RAS prenylation and are associated with hereditary pancreatic cancer Epidemiology. 77: 4272-4272. DOI: 10.1158/1538-7445.Am2017-4272  0.542
2016 Cox AG, Tsomides A, Kim AJ, Saunders D, Hwang KL, Evason KJ, Heidel J, Brown KK, Yuan M, Lien EC, Lee BC, Nissim S, Dickinson B, Chhangawala S, Chang CJ, et al. Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27588899 DOI: 10.1073/Pnas.1600204113  0.594
2016 Nissim S, Weeksb O, Talbot JC, Hedgepeth JW, Wucherpfennig J, Schatzman-Bone S, Swinburne I, Cortes M, Alexa K, Megason S, North TE, Amacher SL, Goessling W. Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development. Developmental Biology. PMID 27474396 DOI: 10.1016/J.Ydbio.2016.07.019  0.624
2016 Cox AG, Hwang KL, Brown KK, Evason KJ, Beltz S, Tsomides A, O'Connor K, Galli GG, Yimlamai D, Chhangawala S, Yuan M, Lien EC, Wucherpfennig J, Nissim S, Minami A, et al. Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth. Nature Cell Biology. PMID 27428308 DOI: 10.1038/Ncb3389  0.603
2015 Mancias JD, Pontano Vaites L, Nissim S, Biancur DE, Kim AJ, Wang X, Liu Y, Goessling W, Kimmelman AC, Harper JW. Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis. Elife. 4. PMID 26436293 DOI: 10.7554/Elife.10308  0.537
2015 Esain V, Kwan W, Carroll KJ, Cortes M, Liu SY, Frechette GM, Sheward LM, Nissim S, Goessling W, North TE. Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity. Stem Cells (Dayton, Ohio). PMID 25931248 DOI: 10.1002/Stem.2044  0.638
2015 Mancias JD, Vaites LP, Nissim S, Biancur DE, Kim AJ, Wang X, Liu Y, Goessling W, Kimmelman AC, Harper JW. Author response: Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis Elife. DOI: 10.7554/Elife.10308.014  0.536
2015 Nissim S, Weeks O, Hedgepeth J, Wucherpfennig J, Wang X, Kimmelman A, Goessling W. Abstract 5148: NR5A2 is essential for pancreas development and affects pancreas carcinogenesis Cancer Research. 75: 5148-5148. DOI: 10.1158/1538-7445.Am2015-5148  0.574
2014 Carroll KJ, Esain V, Garnaas MK, Cortes M, Dovey MC, Nissim S, Frechette GM, Liu SY, Kwan W, Cutting CC, Harris JM, Gorelick DA, Halpern ME, Lawson ND, Goessling W, et al. Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche. Developmental Cell. 29: 437-53. PMID 24871948 DOI: 10.1016/J.Devcel.2014.04.012  0.75
2014 Nissim S, Sherwood RI, Wucherpfennig J, Saunders D, Harris JM, Esain V, Carroll KJ, Frechette GM, Kim AJ, Hwang KL, Cutting CC, Elledge S, North TE, Goessling W. Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth. Developmental Cell. 28: 423-37. PMID 24530296 DOI: 10.1016/J.Devcel.2014.01.006  0.63
2014 Nissim S, Wucherpfennig J, Wang X, Kimmelman A, Goessling W. Abstract 1953: The role of NR5a2 in pancreas development and carcinogenesis Cancer Research. 74: 1953-1953. DOI: 10.1158/1538-7445.Am2014-1953  0.655
2013 Carroll KJ, Dovey MC, Garnaas MK, Cutting CC, Frechette GM, Esain V, Nissim S, Kwan W, Harris JM, Gorelick D, Halpern M, Goessling W, North TE. Estrogens Act As a Dorsal-Ventral Limiting Factor To Pattern The Hematopoietic Stem Cell Niche Blood. 122: 465-465. DOI: 10.1182/Blood.V122.21.465.465  0.764
2013 Nissim S, Wucherpfennig J, Wang X, Kimmelman A, Goessling W. Abstract 2657: The role of NR5A2 in pancreas development and oncogenesis. Cancer Research. 73: 2657-2657. DOI: 10.1158/1538-7445.Am2013-2657  0.647
2013 Carroll K, Dovey M, Cutting C, Garnaas M, Esain V, Frechette G, Nissim S, Kwan W, Harris J, Gorelick D, Halpern M, Goessling W, North T. 17beta-estradiol has a biphasic effect on the formation of hematopoietic stem cells Experimental Hematology. 41: S12. DOI: 10.1016/J.Exphem.2013.05.046  0.73
2011 Nissim S, Idos GE, Wu BU. Genetic Markers of Malignant Transformation in IPMN of the Pancreas: A Meta-Analysis Gastroenterology. 140: S-195. DOI: 10.1016/S0016-5085(11)60786-5  0.315
2007 Scherz PJ, McGlinn E, Nissim S, Tabin CJ. Extended exposure to Sonic hedgehog is required for patterning the posterior digits of the vertebrate limb. Developmental Biology. 308: 343-54. PMID 17610861 DOI: 10.1016/J.Ydbio.2007.05.030  0.744
2007 Nissim S, Allard P, Bandyopadhyay A, Harfe BD, Tabin CJ. Characterization of a novel ectodermal signaling center regulating Tbx2 and Shh in the vertebrate limb. Developmental Biology. 304: 9-21. PMID 17300775 DOI: 10.1016/J.Ydbio.2006.12.010  0.565
2007 McGlinn E, Mao J, Nissim S, McMahon A, Tabin C. Novel molecular mechanisms regulating Shh expression and limb patterning The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A199-C  0.528
2006 Nissim S, Hasso SM, Fallon JF, Tabin CJ. Regulation of Gremlin expression in the posterior limb bud. Developmental Biology. 299: 12-21. PMID 16989805 DOI: 10.1016/J.Ydbio.2006.05.026  0.576
2005 Dentice M, Bandyopadhyay A, Gereben B, Callebaut I, Christoffolete MA, Kim BW, Nissim S, Mornon JP, Zavacki AM, Zeöld A, Capelo LP, Curcio-Morelli C, Ribeiro R, Harney JW, Tabin CJ, et al. The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate. Nature Cell Biology. 7: 698-705. PMID 15965468 DOI: 10.1038/Ncb1272  0.539
2004 Harfe BD, Scherz PJ, Nissim S, Tian H, McMahon AP, Tabin CJ. Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell. 118: 517-28. PMID 15315763 DOI: 10.1016/J.Cell.2004.07.024  0.752
2003 Rallis C, Bruneau BG, Del Buono J, Seidman CE, Seidman JG, Nissim S, Tabin CJ, Logan MP. Tbx5 is required for forelimb bud formation and continued outgrowth. Development (Cambridge, England). 130: 2741-51. PMID 12736217 DOI: 10.1242/Dev.00473  0.557
2002 Park KI, Lachyankar M, Nissim S, Snyder EY. Neural stem cells for CNS repair: state of the art and future directions. Advances in Experimental Medicine and Biology. 506: 1291-6. PMID 12614070 DOI: 10.1007/978-1-4615-0717-8_188  0.38
1999 Park KI, Liu S, Flax JD, Nissim S, Stieg PE, Snyder EY. Transplantation of neural progenitor and stem cells: developmental insights may suggest new therapies for spinal cord and other CNS dysfunction. Journal of Neurotrauma. 16: 675-87. PMID 10511240 DOI: 10.1089/Neu.1999.16.675  0.35
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