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Erik Procko, Ph.D. - Publications

Affiliations: 
University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
 2008 Harvard University, Cambridge, MA, United States 
Area:
Membrane Protein Structure and Function, Molecular Recognition, Neurotransmitters, Taste, G Protein-Coupled Receptors
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chan MC, Chan KK, Procko E, Shukla D. Machine Learning Guided Design of High-Affinity ACE2 Decoys for SARS-CoV-2 Neutralization. The Journal of Physical Chemistry. B. 127: 1995-2001. PMID 36827526 DOI: 10.1021/acs.jpcb.3c00469  0.333
2021 Chan MC, Chan KK, Procko E, Shukla D. Machine learning guided design of high affinity ACE2 decoys for SARS-CoV-2 neutralization. Biorxiv : the Preprint Server For Biology. PMID 34981064 DOI: 10.1101/2021.12.22.473902  0.338
2021 McShan AC, Devlin CA, Morozov GI, Overall SA, Moschidi D, Akella N, Procko E, Sgourakis NG. TAPBPR promotes antigen loading on MHC-I molecules using a peptide trap. Nature Communications. 12: 3174. PMID 34039964 DOI: 10.1038/s41467-021-23225-6  0.311
2020 Chan KK, Dorosky D, Sharma P, Abbasi SA, Dye JM, Kranz DM, Herbert AS, Procko E. Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2. Science (New York, N.Y.). PMID 32753553 DOI: 10.1126/Science.Abc0870  0.423
2020 Park J, Gill KS, Aghajani AA, Heredia JD, Choi H, Oberstein A, Procko E. Engineered receptors for human cytomegalovirus that are orthogonal to normal human biology. Plos Pathogens. 16: e1008647. PMID 32559251 DOI: 10.1371/Journal.Ppat.1008647  0.386
2020 Procko E. The sequence of human ACE2 is suboptimal for binding the S spike protein of SARS coronavirus 2. Biorxiv : the Preprint Server For Biology. PMID 32511321 DOI: 10.1101/2020.03.16.994236  0.407
2020 Zhang J, Kim EC, Chen C, Procko E, Pant S, Lam K, Patel J, Choi R, Hong M, Joshi D, Bolton E, Tajkhorshid E, Chung HJ. Identifying mutation hotspots reveals pathogenetic mechanisms of KCNQ2 epileptic encephalopathy. Scientific Reports. 10: 4756. PMID 32179837 DOI: 10.1038/S41598-020-61697-6  0.378
2019 McShan AC, Devlin CA, Overall SA, Park J, Toor JS, Moschidi D, Flores-Solis D, Choi H, Tripathi S, Procko E, Sgourakis NG. Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection. Proceedings of the National Academy of Sciences of the United States of America. PMID 31796585 DOI: 10.1073/Pnas.1915562116  0.457
2019 Heredia JD, Park J, Choi H, Gill KS, Procko E. Conformational engineering of HIV-1 Env based on mutational tolerance in the CD4 and PG16 bound states. Journal of Virology. PMID 30894475 DOI: 10.1128/Jvi.00219-19  0.396
2019 Park J, Selvam B, Sanematsu K, Shigemura N, Shukla D, Procko E. Structural architecture of a dimeric class C GPCR based on co-trafficking of sweet taste receptor subunits. The Journal of Biological Chemistry. PMID 30723160 DOI: 10.1074/Jbc.Ra118.006173  0.388
2018 Kim EC, Zhang J, Pang W, Wang S, Lee KY, Cavaretta JP, Walters J, Procko E, Tsai NP, Chung HJ. Reduced axonal surface expression and phosphoinositide sensitivity in K7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy. Neurobiology of Disease. 118: 76-93. PMID 30008368 DOI: 10.1016/J.Nbd.2018.07.004  0.338
2018 Heredia JD, Park J, Brubaker RJ, Szymanski SK, Gill KS, Procko E. Mapping Interaction Sites on Human Chemokine Receptors by Deep Mutational Scanning. Journal of Immunology (Baltimore, Md. : 1950). PMID 29678950 DOI: 10.4049/Jimmunol.1800343  0.447
2016 Harris DT, Wang N, Riley TP, Anderson SD, Singh NK, Procko E, Baker BM, Kranz DM. Deep mutational scans as a guide to engineering high-affinity T cell receptor interactions with peptide-bound MHC. The Journal of Biological Chemistry. PMID 27681597 DOI: 10.1074/Jbc.M116.748681  0.404
2016 Harris DT, Singh NK, Cai Q, Smith SN, Vander Kooi CW, Procko E, Kranz DM, Baker BM. An Engineered Switch in T Cell Receptor Specificity Leads to an Unusual but Functional Binding Geometry. Structure (London, England : 1993). PMID 27238970 DOI: 10.1016/J.Str.2016.04.011  0.473
2013 Procko E, Hedman R, Hamilton K, Seetharaman J, Fleishman SJ, Su M, Aramini J, Kornhaber G, Hunt JF, Tong L, Montelione GT, Baker D. Computational design of a protein-based enzyme inhibitor. Journal of Molecular Biology. 425: 3563-75. PMID 23827138 DOI: 10.1016/J.Jmb.2013.06.035  0.407
2013 Geibel S, Procko E, Hultgren SJ, Baker D, Waksman G. Structural and energetic basis of folded-protein transport by the FimD usher. Nature. 496: 243-6. PMID 23579681 DOI: 10.1038/Nature12007  0.378
2012 Lau SY, Procko E, Gaudet R. Distinct properties of Ca2+-calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channel. The Journal of General Physiology. 140: 541-55. PMID 23109716 DOI: 10.1085/Jgp.201210810  0.634
2012 Inada H, Procko E, Sotomayor M, Gaudet R. Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel. Biochemistry. 51: 6195-206. PMID 22702953 DOI: 10.1021/Bi300279B  0.705
2009 Procko E, Gaudet R. Antigen processing and presentation: TAPping into ABC transporters. Current Opinion in Immunology. 21: 84-91. PMID 19261456 DOI: 10.1016/J.Coi.2009.02.003  0.658
2009 Procko E, O'Mara ML, Bennett WF, Tieleman DP, Gaudet R. The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1287-302. PMID 19174475 DOI: 10.1096/Fj.08-121855  0.616
2008 Procko E, Gaudet R. Functionally important interactions between the nucleotide-binding domains of an antigenic peptide transporter. Biochemistry. 47: 5699-708. PMID 18452308 DOI: 10.1021/Bi7024854  0.648
2007 Phelps CB, Procko E, Lishko PV, Wang RR, Gaudet R. Insights into the roles of conserved and divergent residues in the ankyrin repeats of TRPV ion channels. Channels (Austin, Tex.). 1: 148-51. PMID 18690026 DOI: 10.4161/Chan.4716  0.699
2007 Lishko PV, Procko E, Jin X, Phelps CB, Gaudet R. The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity. Neuron. 54: 905-18. PMID 17582331 DOI: 10.1016/J.Neuron.2007.05.027  0.716
2006 Procko E, Ferrin-O'Connell I, Ng SL, Gaudet R. Distinct structural and functional properties of the ATPase sites in an asymmetric ABC transporter. Molecular Cell. 24: 51-62. PMID 17018292 DOI: 10.1016/J.Molcel.2006.07.034  0.654
2005 Procko E, Raghuraman G, Wiley DC, Raghavan M, Gaudet R. Identification of domain boundaries within the N-termini of TAP1 and TAP2 and their importance in tapasin binding and tapasin-mediated increase in peptide loading of MHC class I. Immunology and Cell Biology. 83: 475-82. PMID 16174096 DOI: 10.1111/J.1440-1711.2005.01354.X  0.68
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