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William F. Hawse, Ph.D. - Publications

Affiliations: 
2009 Johns Hopkins University, Baltimore, MD 
Area:
lysine ubiquitination and acetylation, using x-ray crystallography, together with biochemical, biophysical and genetic analysis
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Revu SK, Yang W, Rajasundaram D, Brady A, Majumder S, Gaffen SL, Hawse W, Xia Z, McGeachy MJ. Human IL-17A protein production is controlled through a PIP5K1α-dependent translational checkpoint. Science Signaling. 16: eabo6555. PMID 37874883 DOI: 10.1126/scisignal.abo6555  0.739
2023 Lane S, White TLA, Walsh EE, Cattley RT, Cumberland R, Hawse WF, Delgoffe GM, Badylak SF, Bomberger JM. Antiviral epithelial-macrophage crosstalk permits secondary bacterial infections. Mbio. e0086323. PMID 37772820 DOI: 10.1128/mbio.00863-23  0.701
2023 Ramgopal A, Braverman EL, Sun LK, Monlish D, Wittmann C, Ramsey MJ, Caitley R, Hawse W, Byersdorfer CA. AMPK Drives Both Glycolytic and Oxidative Metabolism in T Cells During Graft-versus-host Disease. Biorxiv : the Preprint Server For Biology. PMID 37398326 DOI: 10.1101/2023.06.12.544686  0.749
2022 Rudd CE, Merida I, Hawse W. Editorial: T-Cell Signaling Networks in Health and Disease. Frontiers in Immunology. 13: 875580. PMID 35464446 DOI: 10.3389/fimmu.2022.875580  0.718
2022 Gordon RA, Giannouli CC, Raparia C, Bastacky SI, Marinov A, Hawse W, Cattley RT, Tilstra JS, Campbell AM, Nickerson KM, Davidson A, Shlomchik MJ. Rubicon promotes clinical and immunological manifestations of SLE in murine models but is not required for LC3-associated phagocytosis (LAP). Jci Insight. PMID 35192551 DOI: 10.1172/jci.insight.155537  0.701
2021 Prado DS, Cattley RT, Shipman CW, Happe C, Lee M, Boggess WC, MacDonald ML, Hawse WF. Synergistic and additive interactions between receptor signaling networks drive the regulatory T cell versus T helper 17 cell fate choice. The Journal of Biological Chemistry. 101330. PMID 34688667 DOI: 10.1016/j.jbc.2021.101330  0.76
2020 Cattley RT, Lee M, Boggess WC, Hawse WF. Transforming growth factor β (TGF-β) receptor signaling regulates kinase networks and phosphatidylinositol metabolism during T-cell activation. The Journal of Biological Chemistry. PMID 32358062 DOI: 10.1074/Jbc.Ra120.012572  0.74
2020 Weisel FJ, Mullett SJ, Elsner RA, Menk AV, Trivedi N, Luo W, Wikenheiser D, Hawse WF, Chikina M, Smita S, Conter LJ, Joachim SM, Wendell SG, Jurczak MJ, Winkler TH, et al. Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis. Nature Immunology. PMID 32066950 DOI: 10.1038/S41590-020-0598-4  0.692
2019 Hawse WF, Cattley RT, Wendell SG. Cutting Edge: TCR Signal Strength Regulates Acetyl-CoA Metabolism via AKT. Journal of Immunology (Baltimore, Md. : 1950). PMID 31628154 DOI: 10.4049/Jimmunol.1900749  0.761
2019 Hernandez-Mir G, Raphael I, Revu S, Poholek CH, Avery L, Hawse WF, Kane LP, McGeachy MJ. The Alzheimer's Disease-Associated Protein BACE1 Modulates T Cell Activation and Th17 Function. Journal of Immunology (Baltimore, Md. : 1950). PMID 31209103 DOI: 10.4049/Jimmunol.1800363  0.763
2019 Piccirillo AR, Hyzny EJ, Beppu LY, Menk AV, Wallace CT, Hawse WF, Buechel HM, Wong BH, Foo JC, Cazenave-Gassiot A, Wenk MR, Delgoffe GM, Watkins SC, Silver DL, D'Cruz LM. The Lysophosphatidylcholine Transporter MFSD2A Is Essential for CD8 Memory T Cell Maintenance and Secondary Response to Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 31127034 DOI: 10.4049/Jimmunol.1801585  0.743
2019 Luo W, Hawse W, Conter L, Trivedi N, Weisel F, Wikenheiser D, Cattley RT, Shlomchik MJ. The AKT kinase signaling network is rewired by PTEN to control proximal BCR signaling in germinal center B cells. Nature Immunology. PMID 31011187 DOI: 10.1038/S41590-019-0376-3  0.727
2019 Hawse WF, Cattley RT. T cells transduce T cell receptor signal strength by generating different phosphatidylinositols. The Journal of Biological Chemistry. PMID 30692200 DOI: 10.1074/Jbc.Ra118.006524  0.745
2018 Piccirillo AR, Cattley RT, D'Cruz LM, Hawse WF. Histone acetyltransferase CBP is critical for conventional effector and memory T-cell differentiation in mice. The Journal of Biological Chemistry. PMID 30573679 DOI: 10.1074/Jbc.Ra118.006977  0.752
2017 Cascio S, Medsger TA, Hawse WF, Watkins SC, Milcarek C, Moreland LW, Lafyatis RA, Fuschiotti P. 14-3-3z sequesters cytosolic T-bet, up-regulating IL-13 in Tc2 and scleroderma CD8+ lymphocytes. The Journal of Allergy and Clinical Immunology. PMID 29155097 DOI: 10.1016/J.Jaci.2017.10.029  0.716
2017 Hawse WF, Boggess WC, Morel PA. TCR Signal Strength Regulates Akt Substrate Specificity To Induce Alternate Murine Th and T Regulatory Cell Differentiation Programs. Journal of Immunology (Baltimore, Md. : 1950). PMID 28600288 DOI: 10.4049/Jimmunol.1700369  0.77
2015 Hawse WF, Sheehan RP, Miskov-Zivanov N, Menk AV, Kane LP, Faeder JR, Morel PA. Cutting Edge: Differential Regulation of PTEN by TCR, Akt, and FoxO1 Controls CD4+ T Cell Fate Decisions. Journal of Immunology (Baltimore, Md. : 1950). 194: 4615-9. PMID 25855357 DOI: 10.4049/Jimmunol.1402554  0.757
2014 Hawse WF, Morel PA. An immunology primer for computational modelers. Journal of Pharmacokinetics and Pharmacodynamics. 41: 389-99. PMID 25238901 DOI: 10.1007/S10928-014-9384-Y  0.686
2014 Morel PA, Faeder JR, Hawse WF, Miskov-Zivanov N. Modeling the T cell immune response: a fascinating challenge. Journal of Pharmacokinetics and Pharmacodynamics. 41: 401-13. PMID 25155903 DOI: 10.1007/S10928-014-9376-Y  0.725
2014 Hawse WF, De S, Greenwood AI, Nicholson LK, Zajicek J, Kovrigin EL, Kranz DM, Garcia KC, Baker BM. TCR scanning of peptide/MHC through complementary matching of receptor and ligand molecular flexibility. Journal of Immunology (Baltimore, Md. : 1950). 192: 2885-91. PMID 24523505 DOI: 10.4049/Jimmunol.1302953  0.783
2013 Hawse WF, Gloor BE, Ayres CM, Kho K, Nuter E, Baker BM. Peptide modulation of class I major histocompatibility complex protein molecular flexibility and the implications for immune recognition. The Journal of Biological Chemistry. 288: 24372-81. PMID 23836912 DOI: 10.1074/Jbc.M113.490664  0.731
2012 Baker BM, Scott DR, Blevins SJ, Hawse WF. Structural and dynamic control of T-cell receptor specificity, cross-reactivity, and binding mechanism. Immunological Reviews. 250: 10-31. PMID 23046120 DOI: 10.1111/J.1600-065X.2012.01165.X  0.753
2012 Hawse WF, Champion MM, Joyce MV, Hellman LM, Hossain M, Ryan V, Pierce BG, Weng Z, Baker BM. Cutting edge: Evidence for a dynamically driven T cell signaling mechanism. Journal of Immunology (Baltimore, Md. : 1950). 188: 5819-23. PMID 22611242 DOI: 10.4049/Jimmunol.1200952  0.796
2009 Hawse WF, Wolberger C. Structure-based mechanism of ADP-ribosylation by sirtuins. The Journal of Biological Chemistry. 284: 33654-61. PMID 19801667 DOI: 10.1074/Jbc.M109.024521  0.774
2008 Hawse WF, Hoff KG, Fatkins DG, Daines A, Zubkova OV, Schramm VL, Zheng W, Wolberger C. Structural insights into intermediate steps in the Sir2 deacetylation reaction. Structure (London, England : 1993). 16: 1368-77. PMID 18786399 DOI: 10.1016/J.Str.2008.05.015  0.762
2007 Garrity J, Gardner JG, Hawse W, Wolberger C, Escalante-Semerena JC. N-lysine propionylation controls the activity of propionyl-CoA synthetase. The Journal of Biological Chemistry. 282: 30239-45. PMID 17684016 DOI: 10.1074/Jbc.M704409200  0.752
2002 Goodson HV, Hawse WF. Molecular evolution of the actin family. Journal of Cell Science. 115: 2619-22. PMID 12077353  0.678
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