| Year |
Citation |
Score |
| 2023 |
Ballegeer M, van Scherpenzeel RC, Delgado T, Iglesias-Caballero M, García Barreno B, Pandey S, Rush SA, Kolkman JA, Mas V, McLellan JS, Saelens X. A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein. Mbio. e0212223. PMID 38117059 DOI: 10.1128/mbio.02122-23 |
0.368 |
|
| 2023 |
Goike J, Hsieh CL, Horton AP, Gardner EC, Zhou L, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Xie X, Xia H, Shi PY, Renberg R, Segall-Shapiro TH, ... ... McLellan JS, et al. SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode. Communications Biology. 6: 1250. PMID 38082099 DOI: 10.1038/s42003-023-05649-6 |
0.388 |
|
| 2023 |
Zehner M, Alt M, Ashurov A, Goldsmith JA, Spies R, Weiler N, Lerma J, Gieselmann L, Stöhr D, Gruell H, Schultz EP, Kreer C, Schlachter L, Janicki H, Laib Sampaio K, ... ... McLellan JS, et al. Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer. Immunity. 56: 2602-2620.e10. PMID 37967532 DOI: 10.1016/j.immuni.2023.10.009 |
0.318 |
|
| 2023 |
Tse LV, Hou YJ, McFadden E, Lee RE, Scobey TD, Leist SR, Martinez DR, Meganck RM, Schäfer A, Yount BL, Mascenik T, Powers JM, Randell SH, Zhang Y, Wang L, ... ... McLellan JS, et al. A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus. Science Translational Medicine. 15: eadg5567. PMID 37756379 DOI: 10.1126/scitranslmed.adg5567 |
0.396 |
|
| 2023 |
McCool RS, Musayev M, Bush SM, Derrien-Colemyn A, Acreman CM, Wrapp D, Ruckwardt TJ, Graham BS, Mascola JR, McLellan JS. Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein elicits antibodies targeting a membrane-proximal epitope. Journal of Virology. e0092923. PMID 37737588 DOI: 10.1128/jvi.00929-23 |
0.614 |
|
| 2023 |
McNamara RP, Maron JS, Boucau J, Roy V, Webb NE, Bertera HL, Barczak AK, Positives Study Staff T, Franko N, Logue JK, Kemp M, Li JZ, Zhou L, Hsieh CL, McLellan JS, et al. Anamnestic humoral correlates of immunity across SARS-CoV-2 variants of concern. Mbio. e0090223. PMID 37535402 DOI: 10.1128/mbio.00902-23 |
0.333 |
|
| 2023 |
Silva RP, Huang Y, Nguyen AW, Hsieh CL, Olaluwoye OS, Kaoud TS, Wilen RE, Qerqez AN, Park JG, Khalil AM, Azouz LR, Le KC, Bohanon AL, DiVenere AM, Liu Y, ... ... McLellan JS, et al. Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses. Elife. 12. PMID 36942851 DOI: 10.7554/eLife.83710 |
0.341 |
|
| 2023 |
Byrne PO, Fisher BE, Ambrozak DR, Blade EG, Tsybovsky Y, Graham BS, McLellan JS, Loomis RJ. Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein. Nature Communications. 14: 1494. PMID 36932063 DOI: 10.1038/s41467-023-36995-y |
0.346 |
|
| 2022 |
Rush SA, Brar G, Hsieh CL, Chautard E, Rainho-Tomko JN, Slade CD, Bricault CA, Kume A, Kearns J, Groppo R, Mundle ST, Zhang L, Casimiro D, Fu TM, DiNapoli JM, ... McLellan JS, et al. Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus. Cell Reports. 40: 111399. PMID 36130517 DOI: 10.1016/j.celrep.2022.111399 |
0.384 |
|
| 2022 |
Goldsmith JA, DiVenere AM, Maynard JA, McLellan JS. Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin. Cell Reports. 40: 111196. PMID 35977491 DOI: 10.1016/j.celrep.2022.111196 |
0.315 |
|
| 2022 |
Rappazzo CG, Hsieh CL, Rush SA, Esterman ES, Delgado T, Geoghegan JC, Wec AZ, Sakharkar M, Más V, McLellan JS, Walker LM. Potently neutralizing and protective anti-human metapneumovirus antibodies target diverse sites on the fusion glycoprotein. Immunity. PMID 35944529 DOI: 10.1016/j.immuni.2022.07.003 |
0.354 |
|
| 2022 |
DiVenere AM, Amengor D, Silva RP, Goldsmith JA, McLellan JS, Maynard JA. Blockade of the Adenylate Cyclase Toxin Synergizes with Opsonizing Antibodies to Protect Mice against Bordetella pertussis. Mbio. e0152722. PMID 35920558 DOI: 10.1128/mbio.01527-22 |
0.317 |
|
| 2022 |
Banerjee A, Huang J, Rush SA, Murray J, Gingerich AD, Royer F, Hsieh CL, Tripp RA, McLellan JS, Mousa JJ. Structural basis for ultrapotent antibody-mediated neutralization of human metapneumovirus. Proceedings of the National Academy of Sciences of the United States of America. 119: e2203326119. PMID 35696580 DOI: 10.1073/pnas.2203326119 |
0.38 |
|
| 2022 |
Hsieh CL, Rush SA, Palomo C, Chou CW, Pickens W, Más V, McLellan JS. Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins. Nature Communications. 13: 1299. PMID 35288548 DOI: 10.1038/s41467-022-28931-3 |
0.315 |
|
| 2022 |
Wrapp D, Ye X, Ku Z, Su H, Jones HG, Wang N, Mishra AK, Freed DC, Li F, Tang A, Li L, Jaijyan DK, Zhu H, Wang D, Fu TM, ... ... McLellan JS, et al. Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies. Science Advances. 8: eabm2546. PMID 35275718 DOI: 10.1126/sciadv.abm2546 |
0.382 |
|
| 2022 |
Costello SM, Shoemaker SR, Hobbs HT, Nguyen AW, Hsieh CL, Maynard JA, McLellan JS, Pak JE, Marqusee S. The SARS-CoV-2 spike reversibly samples an open-trimer conformation exposing novel epitopes. Nature Structural & Molecular Biology. PMID 35236990 DOI: 10.1038/s41594-022-00735-5 |
0.355 |
|
| 2021 |
Chawla H, Jossi SE, Faustini SE, Samsudin F, Allen JD, Watanabe Y, Newby ML, Marcial-Juárez E, Lamerton RE, McLellan JS, Bond PJ, Richter AG, Cunningham AF, Crispin M. Glycosylation and Serological Reactivity of an Expression-enhanced SARS-CoV-2 Viral Spike Mimetic. Journal of Molecular Biology. 434: 167332. PMID 34717971 DOI: 10.1016/j.jmb.2021.167332 |
0.325 |
|
| 2021 |
Haslwanter D, Dieterle ME, Wec AZ, O'Brien CM, Sakharkar M, Florez C, Tong K, Rappazzo CG, Lasso G, Vergnolle O, Wirchnianski AS, Bortz RH, Laudermilch E, Fels JM, Mengotto A, ... ... McLellan JS, et al. A Combination of Receptor-Binding Domain and N-Terminal Domain Neutralizing Antibodies Limits the Generation of SARS-CoV-2 Spike Neutralization-Escape Mutants. Mbio. e0247321. PMID 34607456 DOI: 10.1128/mBio.02473-21 |
0.404 |
|
| 2021 |
Li T, Xue W, Zheng Q, Song S, Yang C, Xiong H, Zhang S, Hong M, Zhang Y, Yu H, Zhang Y, Sun H, Huang Y, Deng T, Chi X, ... ... McLellan JS, et al. Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants. Nature Communications. 12: 5652. PMID 34580306 DOI: 10.1038/s41467-021-25997-3 |
0.379 |
|
| 2021 |
Goldsmith JA, DiVenere AM, Maynard JA, McLellan JS. Structural basis for antibody binding to adenylate cyclase toxin reveals RTX linkers as neutralization-sensitive epitopes. Plos Pathogens. 17: e1009920. PMID 34547035 DOI: 10.1371/journal.ppat.1009920 |
0.372 |
|
| 2021 |
Andreano E, Piccini G, Licastro D, Casalino L, Johnson NV, Paciello I, Dal Monego S, Pantano E, Manganaro N, Manenti A, Manna R, Casa E, Hyseni I, Benincasa L, Montomoli E, ... ... McLellan JS, et al. SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34417349 DOI: 10.1073/pnas.2103154118 |
0.347 |
|
| 2021 |
Sztain T, Ahn SH, Bogetti AT, Casalino L, Goldsmith JA, Seitz E, McCool RS, Kearns FL, Acosta-Reyes F, Maji S, Mashayekhi G, McCammon JA, Ourmazd A, Frank J, McLellan JS, et al. A glycan gate controls opening of the SARS-CoV-2 spike protein. Nature Chemistry. PMID 34413500 DOI: 10.1038/s41557-021-00758-3 |
0.653 |
|
| 2021 |
Fels JM, Maurer DP, Herbert AS, Wirchnianski AS, Vergnolle O, Cross RW, Abelson DM, Moyer CL, Mishra AK, Aguilan JT, Kuehne AI, Pauli NT, Bakken RR, Nyakatura EK, Hellert J, ... ... McLellan JS, et al. Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever. Cell. PMID 34077751 DOI: 10.1016/j.cell.2021.05.001 |
0.362 |
|
| 2021 |
Shiakolas AR, Kramer KJ, Wrapp D, Richardson SI, Schäfer A, Wall S, Wang N, Janowska K, Pilewski KA, Venkat R, Parks R, Manamela NP, Raju N, Fechter EF, Holt CM, ... ... McLellan JS, et al. Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions. Cell Reports. Medicine. 100313. PMID 34056628 DOI: 10.1016/j.xcrm.2021.100313 |
0.33 |
|
| 2021 |
Voss WN, Hou YJ, Johnson NV, Delidakis G, Kim JE, Javanmardi K, Horton AP, Bartzoka F, Paresi CJ, Tanno Y, Chou CW, Abbasi SA, Pickens W, George K, Boutz DR, ... ... McLellan JS, et al. Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes. Science (New York, N.Y.). PMID 33947773 DOI: 10.1126/science.abg5268 |
0.346 |
|
| 2021 |
Goike J, Hsieh CL, Horton A, Gardner EC, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Renberg R, Johanson MJ, Cardona JA, Segall-Shapiro T, Zhou L, Nissly RH, ... ... McLellan JS, et al. Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality. Biorxiv : the Preprint Server For Biology. PMID 33851158 DOI: 10.1101/2021.04.07.438849 |
0.399 |
|
| 2021 |
Mukhamedova M, Wrapp D, Shen CH, Gilman MSA, Ruckwardt TJ, Schramm CA, Ault L, Chang L, Derrien-Colemyn A, Lucas SAM, Ransier A, Darko S, Phung E, Wang L, Zhang Y, ... ... McLellan JS, et al. Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity. PMID 33823129 DOI: 10.1016/j.immuni.2021.03.004 |
0.316 |
|
| 2021 |
Jones BE, Brown-Augsburger PL, Corbett KS, Westendorf K, Davies J, Cujec TP, Wiethoff CM, Blackbourne JL, Heinz BA, Foster D, Higgs RE, Balasubramaniam D, Wang L, Zhang Y, Yang ES, ... ... McLellan JS, et al. The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in non-human primates. Science Translational Medicine. PMID 33820835 DOI: 10.1126/scitranslmed.abf1906 |
0.374 |
|
| 2021 |
Rossey I, Hsieh CL, Sedeyn K, Ballegeer M, Schepens B, Mclellan JS, Saelens X. A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody. Journal of Virology. PMID 33692208 DOI: 10.1128/JVI.02279-20 |
0.376 |
|
| 2021 |
Sztain T, Ahn SH, Bogetti AT, Casalino L, Goldsmith JA, McCool RS, Kearns FL, McCammon JA, McLellan JS, Chong LT, Amaro RE. A glycan gate controls opening of the SARS-CoV-2 spike protein. Biorxiv : the Preprint Server For Biology. PMID 33619492 DOI: 10.1101/2021.02.15.431212 |
0.655 |
|
| 2021 |
Rappazzo CG, Tse LV, Kaku CI, Wrapp D, Sakharkar M, Huang D, Deveau LM, Yockachonis TJ, Herbert AS, Battles MB, O'Brien CM, Brown ME, Geoghegan JC, Belk J, Peng L, ... ... McLellan JS, et al. Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody. Science (New York, N.Y.). PMID 33495307 DOI: 10.1126/science.abf4830 |
0.345 |
|
| 2021 |
Ku Z, Xie X, Davidson E, Ye X, Su H, Menachery VD, Li Y, Yuan Z, Zhang X, Muruato AE, I Escuer AG, Tyrell B, Doolan K, Doranz BJ, Wrapp D, ... ... McLellan JS, et al. Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape. Nature Communications. 12: 469. PMID 33473140 DOI: 10.1038/s41467-020-20789-7 |
0.326 |
|
| 2020 |
Andreano E, Piccini G, Licastro D, Casalino L, Johnson NV, Paciello I, Monego SD, Pantano E, Manganaro N, Manenti A, Manna R, Casa E, Hyseni I, Benincasa L, Montomoli E, ... ... McLellan JS, et al. SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma. Biorxiv : the Preprint Server For Biology. PMID 33398278 DOI: 10.1101/2020.12.28.424451 |
0.329 |
|
| 2020 |
Shiakolas AR, Kramer KJ, Wrapp D, Richardson SI, Schäfer A, Wall S, Wang N, Janowska K, Pilewski KA, Venkat R, Parks R, Manamela NP, Raju N, Fechter EF, Holt CM, ... ... McLellan JS, et al. Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions. Biorxiv : the Preprint Server For Biology. PMID 33398266 DOI: 10.1101/2020.12.20.414748 |
0.365 |
|
| 2020 |
Rappazzo CG, Tse LV, Kaku CI, Wrapp D, Sakharkar M, Huang D, Deveau LM, Yockachonis TJ, Herbert AS, Battles MB, O'Brien CM, Brown ME, Geoghegan JC, Belk J, Peng L, ... ... McLellan JS, et al. An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19. Biorxiv : the Preprint Server For Biology. PMID 33236009 DOI: 10.1101/2020.11.17.385500 |
0.367 |
|
| 2020 |
Casalino L, Gaieb Z, Goldsmith JA, Hjorth CK, Dommer AC, Harbison AM, Fogarty CA, Barros EP, Taylor BC, McLellan JS, Fadda E, Amaro RE. Beyond Shielding: The Roles of Glycans in the SARS-CoV-2 Spike Protein. Acs Central Science. 6: 1722-1734. PMID 33140034 DOI: 10.1021/acscentsci.0c01056 |
0.44 |
|
| 2020 |
Jones BE, Brown-Augsburger PL, Corbett KS, Westendorf K, Davies J, Cujec TP, Wiethoff CM, Blackbourne JL, Heinz BA, Foster D, Higgs RE, Balasubramaniam D, Wang L, Bidshahri R, Kraft L, ... ... McLellan JS, et al. LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection. Biorxiv : the Preprint Server For Biology. PMID 33024963 DOI: 10.1101/2020.09.30.318972 |
0.38 |
|
| 2020 |
Goodwin ML, Webster HS, Wang HY, Jenks JA, Nelson CS, Tu JJ, Mangold JF, Valencia S, Pollara J, Edwards W, McLellan JS, Wrapp D, Fu TM, Zhang N, Freed DC, et al. Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection. Virology. 548: 182-191. PMID 32838941 DOI: 10.1016/J.Virol.2020.07.009 |
0.372 |
|
| 2020 |
Ye X, Su H, Wrapp D, Freed DC, Li F, Yuan Z, Tang A, Li L, Ku Z, Xiong W, Jaijyan D, Zhu H, Wang D, McLellan JS, Zhang N, et al. Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step. Plos Pathogens. 16: e1008736. PMID 32745149 DOI: 10.1371/Journal.Ppat.1008736 |
0.373 |
|
| 2020 |
Melero R, Sorzano COS, Foster B, Vilas JL, Martínez M, Marabini R, Ramírez-Aportela E, Sanchez-Garcia R, Herreros D, Del Caño L, Losana P, Fonseca-Reyna YC, Conesa P, Wrapp D, Chacon P, ... McLellan JS, et al. Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures. Biorxiv : the Preprint Server For Biology. PMID 32676604 DOI: 10.1101/2020.07.08.191072 |
0.31 |
|
| 2020 |
Loomis RJ, Stewart-Jones GBE, Tsybovsky Y, Caringal RT, Morabito KM, McLellan JS, Chamberlain AL, Nugent ST, Hutchinson GB, Kueltzo LA, Mascola JR, Graham BS. Structure-Based Design of Nipah Virus Vaccines: A Generalizable Approach to Paramyxovirus Immunogen Development. Frontiers in Immunology. 11: 842. PMID 32595632 DOI: 10.3389/Fimmu.2020.00842 |
0.316 |
|
| 2020 |
Wec AZ, Wrapp D, Herbert AS, Maurer DP, Haslwanter D, Sakharkar M, Jangra RK, Dieterle ME, Lilov A, Huang D, Tse LV, Johnson NV, Hsieh CL, Wang N, Nett JH, ... ... McLellan JS, et al. Broad neutralization of SARS-related viruses by human monoclonal antibodies. Science (New York, N.Y.). PMID 32540900 DOI: 10.1126/Science.Abc7424 |
0.341 |
|
| 2020 |
Wec AZ, Wrapp D, Herbert AS, Maurer D, Haslwanter D, Sakharkar M, Jangra RK, Dieterle ME, Lilov A, Huang D, Tse LV, Johnson NV, Hsieh CL, Wang N, Nett JH, ... ... McLellan JS, et al. Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein. Biorxiv : the Preprint Server For Biology. PMID 32511337 DOI: 10.1101/2020.05.15.096511 |
0.38 |
|
| 2020 |
Watanabe Y, Allen JD, Wrapp D, McLellan JS, Crispin M. Site-specific analysis of the SARS-CoV-2 glycan shield. Biorxiv : the Preprint Server For Biology. PMID 32511336 DOI: 10.1101/2020.03.26.010322 |
0.312 |
|
| 2020 |
Wrapp D, Wang N, Corbett KS, Goldsmith JA, Hsieh CL, Abiona O, Graham BS, McLellan JS. Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation. Biorxiv : the Preprint Server For Biology. PMID 32511295 DOI: 10.1101/2020.02.11.944462 |
0.34 |
|
| 2020 |
Watanabe Y, Berndsen ZT, Raghwani J, Seabright GE, Allen JD, Pybus OG, McLellan JS, Wilson IA, Bowden TA, Ward AB, Crispin M. Vulnerabilities in coronavirus glycan shields despite extensive glycosylation. Nature Communications. 11: 2688. PMID 32461612 DOI: 10.1038/S41467-020-16567-0 |
0.324 |
|
| 2020 |
Smith TRF, Patel A, Ramos S, Elwood D, Zhu X, Yan J, Gary EN, Walker SN, Schultheis K, Purwar M, Xu Z, Walters J, Bhojnagarwala P, Yang M, Chokkalingam N, ... ... McLellan JS, et al. Immunogenicity of a DNA vaccine candidate for COVID-19. Nature Communications. 11: 2601. PMID 32433465 DOI: 10.1038/S41467-020-16505-0 |
0.306 |
|
| 2020 |
Choi JH, Woo HM, Lee TY, Lee SY, Shim SM, Park WJ, Yang JS, Kim JA, Yun MR, Kim DW, Kim SS, Zhang Y, Shi W, Wang L, Graham BS, ... ... McLellan JS, et al. Characterization of a human monoclonal antibody generated from a B-cell specific for a prefusion-stabilized spike protein of Middle East respiratory syndrome coronavirus. Plos One. 15: e0232757. PMID 32384116 DOI: 10.1371/Journal.Pone.0232757 |
0.356 |
|
| 2020 |
Wrapp D, De Vlieger D, Corbett KS, Torres GM, Wang N, Van Breedam W, Roose K, van Schie L, Hoffmann M, Pöhlmann S, Graham BS, Callewaert N, Schepens B, Saelens X, ... McLellan JS, et al. Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies. Cell. PMID 32375025 DOI: 10.1016/J.Cell.2020.04.031 |
0.345 |
|
| 2020 |
Watanabe Y, Allen JD, Wrapp D, McLellan JS, Crispin M. Site-specific glycan analysis of the SARS-CoV-2 spike. Science (New York, N.Y.). PMID 32366695 DOI: 10.1126/science.abb9983 |
0.316 |
|
| 2020 |
Wrapp D, Wang N, Corbett KS, Goldsmith JA, Hsieh CL, Abiona O, Graham BS, McLellan JS. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science (New York, N.Y.). PMID 32075877 DOI: 10.1126/Science.Abb2507 |
0.323 |
|
| 2020 |
Pino P, Kint J, Kiseljak D, Agnolon V, Corradin G, Kajava AV, Rovero P, Dijkman R, den Hartog G, McLellan JS, Byrne PO, Wurm MJ, Wurm FM. Trimeric SARS-CoV-2 Spike Proteins Produced from CHO Cells in Bioreactors Are High-Quality Antigens Processes. 8: 1539. DOI: 10.3390/pr8121539 |
0.376 |
|
| 2019 |
Wang N, Rosen O, Wang L, Turner HL, Stevens LJ, Corbett KS, Bowman CA, Pallesen J, Shi W, Zhang Y, Leung K, Kirchdoerfer RN, Becker MM, Denison MR, Chappell JD, ... ... McLellan JS, et al. Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD. Cell Reports. 28: 3395-3405.e6. PMID 31553909 DOI: 10.1016/J.Celrep.2019.08.052 |
0.338 |
|
| 2019 |
Wrapp D, McLellan JS. The 3.1 Å cryo-EM structure of the porcine epidemic diarrhea virus spike protein in the prefusion conformation. Journal of Virology. PMID 31534041 DOI: 10.1128/JVI.00923-19 |
0.433 |
|
| 2019 |
Jones HG, Battles MB, Lin CC, Bianchi S, Corti D, McLellan JS. Alternative conformations of a major antigenic site on RSV F. Plos Pathogens. 15: e1007944. PMID 31306469 DOI: 10.1371/journal.ppat.1007944 |
0.363 |
|
| 2019 |
Gilman MSA, Furmanova-Hollenstein P, Pascual G, B van 't Wout A, Langedijk JPM, McLellan JS. Transient opening of trimeric prefusion RSV F proteins. Nature Communications. 10: 2105. PMID 31068578 DOI: 10.1038/S41467-019-09807-5 |
0.326 |
|
| 2018 |
Rosen O, Chan LL, Abiona O, Gough P, Wang L, Shi W, Zhang Y, Wang N, Kong WP, McLellan JS, Graham BS, Corbett KS. A high-throughput inhibition assay to study MERS-CoV antibody interactions using image cytometry. Journal of Virological Methods. PMID 30468747 DOI: 10.1016/J.Jviromet.2018.11.009 |
0.342 |
|
| 2018 |
Hicks SN, Chaiwatpongsakorn S, Costello HM, McLellan JS, Ray W, Peeples ME. Five Residues in the Apical Loop of the Respiratory Syncytial Virus Fusion Protein F Subunit are Critical for its Fusion Activity. Journal of Virology. PMID 29743373 DOI: 10.1128/Jvi.00621-18 |
0.338 |
|
| 2018 |
Wang L, Shi W, Chappell JD, Joyce MG, Zhang Y, Kanekiyo M, Becker MM, van Doremalen N, Fischer R, Wang N, Corbett KS, Choe M, Mason RD, Van Galen JG, Zhou T, ... ... McLellan JS, et al. Importance of neutralizing monoclonal antibodies targeting multiple antigenic sites on MERS-CoV Spike to avoid neutralization escape. Journal of Virology. PMID 29514901 DOI: 10.1128/JVI.02002-17 |
0.405 |
|
| 2018 |
Jones HG, Ritschel T, Pascual G, Brakenhoff JPJ, Keogh E, Furmanova-Hollenstein P, Lanckacker E, Wadia JS, Gilman MSA, Williamson RA, Roymans D, van 't Wout AB, Langedijk JP, McLellan JS. Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies. Plos Pathogens. 14: e1006935. PMID 29509814 DOI: 10.1371/Journal.Ppat.1006935 |
0.341 |
|
| 2018 |
Goodwin E, Gilman MSA, Wrapp D, Chen M, Ngwuta JO, Moin SM, Bai P, Sivasubramanian A, Connor RI, Wright PF, Graham BS, McLellan JS, Walker LM. Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation. Immunity. PMID 29396163 DOI: 10.1016/J.Immuni.2018.01.005 |
0.318 |
|
| 2017 |
Olmedillas E, Cano O, Martínez I, Luque D, Terrón MC, McLellan JS, Melero JA, Más V. Chimeric Pneumoviridae fusion proteins as immunogens to induce cross-neutralizing antibody responses. Embo Molecular Medicine. PMID 29217660 DOI: 10.15252/Emmm.201708078 |
0.365 |
|
| 2017 |
Tian D, Battles MB, Moin SM, Chen M, Modjarrad K, Kumar A, Kanekiyo M, Graepel KW, Taher NM, Hotard AL, Moore ML, Zhao M, Zheng ZZ, Xia NS, McLellan JS, et al. Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein. Nature Communications. 8: 1877. PMID 29187732 DOI: 10.1038/S41467-017-01858-W |
0.338 |
|
| 2017 |
Rossey I, Gilman MSA, Kabeche SC, Sedeyn K, Wrapp D, Kanekiyo M, Chen M, Mas V, Spitaels J, Melero JA, Graham BS, Schepens B, McLellan JS, Saelens X. Corrigendum: Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nature Communications. 8: 16165. PMID 29184149 DOI: 10.1038/Ncomms16165 |
0.311 |
|
| 2017 |
Rossey I, McLellan JS, Saelens X, Schepens B. Clinical Potential of Prefusion RSV F-specific Antibodies. Trends in Microbiology. PMID 29054341 DOI: 10.1016/j.tim.2017.09.009 |
0.327 |
|
| 2017 |
Pallesen J, Wang N, Corbett KS, Wrapp D, Kirchdoerfer RN, Turner HL, Cottrell CA, Becker MM, Wang L, Shi W, Kong WP, Andres EL, Kettenbach AN, Denison MR, Chappell JD, ... ... McLellan JS, et al. Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen. Proceedings of the National Academy of Sciences of the United States of America. PMID 28807998 DOI: 10.1073/Pnas.1707304114 |
0.377 |
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| 2017 |
Zhao M, Zheng ZZ, Chen M, Modjarrad K, Zhang W, Zhan LT, Cao JL, Sun YP, McLellan JS, Graham BS, Xia NS. Discovery of a Prefusion RSV F-Specific Monoclonal Antibody that Provides Greater in vivo Protection than the Murine Precursor of Palivizumab. Journal of Virology. PMID 28539438 DOI: 10.1128/Jvi.00176-17 |
0.346 |
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| 2017 |
Leemans A, De Schryver M, Van der Gucht W, Heykers A, Pintelon I, Hotard AL, Moore ML, Melero JA, McLellan JS, Graham BS, Broadbent L, Power UF, Caljon G, Cos P, Maes L, et al. Antibody-induced internalization of the human respiratory syncytial virus fusion protein. Journal of Virology. PMID 28468888 DOI: 10.1128/Jvi.00184-17 |
0.4 |
|
| 2017 |
Rossey I, Gilman MS, Kabeche SC, Sedeyn K, Wrapp D, Kanekiyo M, Chen M, Mas V, Spitaels J, Melero JA, Graham BS, Schepens B, McLellan JS, Saelens X. Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nature Communications. 8: 14158. PMID 28194013 DOI: 10.1038/Ncomms14158 |
0.391 |
|
| 2017 |
Ha S, Li F, Troutman MC, Freed DC, Tang A, Loughney JW, Wang D, Wang IM, Vlasak J, Nickle DC, Rustandi RR, Hamm M, DePhillips PA, Zhang N, McLellan JS, et al. Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targets Viral gH/gL/pUL128-131 Pentameric Complex. Journal of Virology. PMID 28077654 DOI: 10.1128/Jvi.02033-16 |
0.304 |
|
| 2016 |
Gilman MS, Castellanos CA, Chen M, Ngwuta JO, Goodwin E, Moin SM, Mas V, Melero JA, Wright PF, Graham BS, McLellan JS, Walker LM. Rapid profiling of RSV antibody repertoires from the memory B cells of naturally infected adult donors. Science Immunology. 1. PMID 28111638 DOI: 10.1126/Sciimmunol.Aaj1879 |
0.362 |
|
| 2016 |
Más V, Rodriguez L, Olmedillas E, Cano O, Palomo C, Terrón MC, Luque D, Melero JA, McLellan JS. Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation. Plos Pathogens. 12: e1005859. PMID 27611367 DOI: 10.1371/Journal.Ppat.1005859 |
0.334 |
|
| 2016 |
Liang B, Ngwuta JO, Herbert R, Swerczek J, Dorward DW, Amaro-Carambot E, Mackow N, Kabatova B, Lingemann M, Surman S, Yang L, Chen M, Moin SM, Kumar A, McLellan JS, et al. Packaging and prefusion stabilization separately and additively increase the quantity and quality of RSV-neutralizing antibodies induced by respiratory syncytial virus (RSV) fusion protein expressed by a parainfluenza vector. Journal of Virology. PMID 27581977 DOI: 10.1128/Jvi.01196-16 |
0.314 |
|
| 2016 |
Hervé PL, Deloizy C, Descamps D, Rameix-Welti MA, Fix J, McLellan JS, Eléouët JF, Riffault S. RSV N-nanorings fused to palivizumab-targeted neutralizing epitope as a nanoparticle RSV vaccine. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 27553073 DOI: 10.1016/j.nano.2016.08.006 |
0.339 |
|
| 2016 |
Kirchdoerfer RN, Cottrell CA, Wang N, Pallesen J, Yassine HM, Turner HL, Corbett KS, Graham BS, McLellan JS, Ward AB. Pre-fusion structure of a human coronavirus spike protein. Nature. 531: 118-21. PMID 26935699 DOI: 10.1038/Nature17200 |
0.41 |
|
| 2015 |
Battles MB, Langedijk JP, Furmanova-Hollenstein P, Chaiwatpongsakorn S, Costello HM, Kwanten L, Vranckx L, Vink P, Jaensch S, Jonckers TH, Koul A, Arnoult E, Peeples ME, Roymans D, McLellan JS. Molecular mechanism of respiratory syncytial virus fusion inhibitors. Nature Chemical Biology. PMID 26641933 DOI: 10.1038/Nchembio.1982 |
0.309 |
|
| 2015 |
Ngwuta JO, Chen M, Modjarrad K, Joyce MG, Kanekiyo M, Kumar A, Yassine HM, Moin SM, Killikelly AM, Chuang GY, Druz A, Georgiev IS, Rundlet EJ, Sastry M, Stewart-Jones GB, ... ... McLellan JS, et al. Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human sera. Science Translational Medicine. 7: 309ra162. PMID 26468324 DOI: 10.1126/Scitranslmed.Aac4241 |
0.351 |
|
| 2015 |
Krarup A, Truan D, Furmanova-Hollenstein P, Bogaert L, Bouchier P, Bisschop IJ, Widjojoatmodjo MN, Zahn R, Schuitemaker H, McLellan JS, Langedijk JP. A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism. Nature Communications. 6: 8143. PMID 26333350 DOI: 10.1038/ncomms9143 |
0.321 |
|
| 2015 |
Gilman MS, Moin SM, Mas V, Chen M, Patel NK, Kramer K, Zhu Q, Kabeche SC, Kumar A, Palomo C, Beaumont T, Baxa U, Ulbrandt ND, Melero JA, Graham BS, ... McLellan JS, et al. Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein. Plos Pathogens. 11: e1005035. PMID 26161532 DOI: 10.1371/Journal.Ppat.1005035 |
0.339 |
|
| 2015 |
McLellan JS. Neutralizing epitopes on the respiratory syncytial virus fusion glycoprotein. Current Opinion in Virology. 11: 70-5. PMID 25819327 DOI: 10.1016/j.coviro.2015.03.002 |
0.302 |
|
| 2014 |
Acharya P, Tolbert WD, Gohain N, Wu X, Yu L, Liu T, Huang W, Huang CC, Kwon YD, Louder RK, Luongo TS, McLellan JS, Pancera M, Yang Y, Zhang B, et al. Structural definition of an antibody-dependent cellular cytotoxicity response implicated in reduced risk for HIV-1 infection. Journal of Virology. 88: 12895-906. PMID 25165110 DOI: 10.1128/JVI.02194-14 |
0.322 |
|
| 2013 |
McLellan JS, Ray WC, Peeples ME. Structure and function of respiratory syncytial virus surface glycoproteins. Current Topics in Microbiology and Immunology. 372: 83-104. PMID 24362685 DOI: 10.1007/978-3-642-38919-1_4 |
0.315 |
|
| 2013 |
McLellan JS, Chen M, Joyce MG, Sastry M, Stewart-Jones GB, Yang Y, Zhang B, Chen L, Srivatsan S, Zheng A, Zhou T, Graepel KW, Kumar A, Moin S, Boyington JC, et al. Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science (New York, N.Y.). 342: 592-8. PMID 24179220 DOI: 10.1126/Science.1243283 |
0.32 |
|
| 2011 |
McLellan JS, Yang Y, Graham BS, Kwong PD. Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes. Journal of Virology. 85: 7788-96. PMID 21613394 DOI: 10.1128/Jvi.00555-11 |
0.308 |
|
| 2011 |
McLellan JS, Correia BE, Chen M, Yang Y, Graham BS, Schief WR, Kwong PD. Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus. Journal of Molecular Biology. 409: 853-66. PMID 21549714 DOI: 10.1016/J.Jmb.2011.04.044 |
0.387 |
|
| 2010 |
McLellan JS, Chen M, Chang JS, Yang Y, Kim A, Graham BS, Kwong PD. Structure of a major antigenic site on the respiratory syncytial virus fusion glycoprotein in complex with neutralizing antibody 101F. Journal of Virology. 84: 12236-44. PMID 20881049 DOI: 10.1128/Jvi.01579-10 |
0.341 |
|
| 2010 |
McLellan JS, Chen M, Kim A, Yang Y, Graham BS, Kwong PD. Structural basis of respiratory syncytial virus neutralization by motavizumab. Nature Structural & Molecular Biology. 17: 248-50. PMID 20098425 DOI: 10.1038/Nsmb.1723 |
0.305 |
|
| 2008 |
McLellan JS, Zheng X, Hauk G, Ghirlando R, Beachy PA, Leahy DJ. The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla. Nature. 455: 979-83. PMID 18794898 DOI: 10.1038/Nature07358 |
0.615 |
|
| 2007 |
Zhang F, McLellan JS, Ayala AM, Leahy DJ, Linhardt RJ. Kinetic and structural studies on interactions between heparin or heparan sulfate and proteins of the hedgehog signaling pathway. Biochemistry. 46: 3933-41. PMID 17348690 DOI: 10.1021/Bi6025424 |
0.571 |
|
| 2006 |
McLellan JS, Yao S, Zheng X, Geisbrecht BV, Ghirlando R, Beachy PA, Leahy DJ. Structure of a heparin-dependent complex of Hedgehog and Ihog. Proceedings of the National Academy of Sciences of the United States of America. 103: 17208-13. PMID 17077139 DOI: 10.1073/Pnas.0606738103 |
0.602 |
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