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Thomas B. Nutman - Publications

Affiliations: 
Microbiology & Emerging Infectious Diseases The George Washington University, Washington, DC, United States 
Area:
Immunology, Parasitology, Microbiology
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343 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Petralia LMC, van Diepen A, Nguyen DL, Lokker LA, Sartono E, Bennuru S, Nutman TB, Pfarr K, Hoerauf A, Wanji S, Foster JM, Hokke CH. Unraveling cross-reactivity of anti-glycan IgG responses in filarial nematode infections. Frontiers in Immunology. 14: 1102344. PMID 36949937 DOI: 10.3389/fimmu.2023.1102344  0.335
2020 Rajamanickam A, Munisankar S, Menon PA, Dolla C, Nutman TB, Babu S. Helminth Mediated Attenuation of Systemic Inflammation and Microbial Translocation in Helminth-Diabetes Comorbidity. Frontiers in Cellular and Infection Microbiology. 10: 431. PMID 32984066 DOI: 10.3389/Fcimb.2020.00431  0.319
2020 Hertz MI, Rush A, Nutman TB, Weil GJ, Bennuru S, Budge PJ. Characterization of glycan determinants that mediate recognition of the major Wuchereria bancrofti circulating antigen by diagnostic antibodies. Molecular and Biochemical Parasitology. 240: 111317. PMID 32961208 DOI: 10.1016/J.Molbiopara.2020.111317  0.355
2020 Legrand F, Herrick J, Makiya M, Ramanathan R, Thompson R, Rampertaap S, Stoddard J, Ware J, Fay MP, Holland-Thomas N, Nutman TB, Klion AD. A randomized, placebo-controlled, double-blind pilot study of single-dose humanized anti-IL5 antibody (reslizumab) for the reduction of eosinophilia following diethylcarbamazine treatment of Loa loa infection. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 32910141 DOI: 10.1093/Cid/Ciaa1365  0.366
2020 Ricciardi A, Nutman TB. IL-10 and its related superfamily members IL-19 and IL-24 provide parallel/redundant immune-modulation in Loa loa infection. The Journal of Infectious Diseases. PMID 32561912 DOI: 10.1093/Infdis/Jiaa347  0.395
2020 Kumar NP, Kathamuthu GR, Moideen K, Banurekha VV, Nair D, Fay MP, Nutman TB, Babu S. Strongyloides stercoralis coinfection is associated with greater disease severity, higher bacterial burden and elevated plasma matrix metalloproteinases in pulmonary tuberculosis. The Journal of Infectious Diseases. PMID 32307511 DOI: 10.1093/Infdis/Jiaa194  0.307
2020 Lee SH, Chaves MM, Kamenyeva O, Gazzinelli-Guimaraes PH, Kang B, Pessenda G, Passelli K, Tacchini-Cottier F, Kabat J, Jacobsen EA, Nutman TB, Sacks DL. M2-like, dermal macrophages are maintained via IL-4/CCL24-mediated cooperative interaction with eosinophils in cutaneous leishmaniasis. Science Immunology. 5. PMID 32276966 DOI: 10.1126/Sciimmunol.Aaz4415  0.37
2020 Horton J, Klarmann-Schulz U, Stephens M, Budge PJ, Coulibaly Y, Debrah A, Debrah LB, Krishnasastry S, Mwingira U, Ngenya A, Wanji S, Weerasooriya M, Yahathugoda C, Kroidl I, Deathe D, ... ... Nutman TB, et al. The design and development of a multicentric protocol to investigate the impact of adjunctive doxycycline on the management of peripheral lymphoedema caused by lymphatic filariasis and podoconiosis. Parasites & Vectors. 13: 155. PMID 32228663 DOI: 10.1186/S13071-020-04024-2  0.314
2020 Clark E, Pritchard H, Hemmige V, Restrepo A, Bautista K, Damania A, Ricciardi A, Nutman TB, Mejia R. Strongyloides stercoralis Infection in Solid Organ Transplant Patients is Associated with Eosinophil Activation and Intestinal Inflammation: A Cross-sectional Study. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 32155244 DOI: 10.1093/Cid/Ciaa233  0.302
2020 Rajamanickam A, Munisankar S, Dolla C, Menon PA, Thiruvengadam K, Nutman TB, Babu S. Helminth infection modulates systemic pro-inflammatory cytokines and chemokines implicated in type 2 diabetes mellitus pathogenesis. Plos Neglected Tropical Diseases. 14: e0008101. PMID 32126084 DOI: 10.1371/Journal.Pntd.0008101  0.311
2020 Herrick JA, Makiya MA, Holland-Thomas N, Klion AD, Nutman TB. Infection-associated Immune Perturbations Resolve One Year Following Treatment for Loa loa. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 32055862 DOI: 10.1093/Cid/Ciaa137  0.384
2020 Rajamanickam A, Munisankar S, Dolla C, Menon PA, Nutman TB, Babu S. Helminth Coinfection Alters Monocyte Activation, Polarization, and Function in Latent Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 31953351 DOI: 10.4049/Jimmunol.1901127  0.432
2020 Keiser PB, Nutman TB. Update on Lymphatic Filarial Infections. Current Infectious Disease Reports. 4: 65-69. PMID 11853659 DOI: 10.1007/S11908-002-0069-0  0.403
2019 Pion SD, Nana-Djeunga H, Niamsi-Emalio Y, Chesnais CB, Deléglise H, Mackenzie C, Stolk W, Fletcher DA, Klion AD, Nutman TB, Boussinesq M, Kamgno J. Implications for annual retesting after a test-and-not-treat strategy for onchocerciasis elimination in areas co-endemic with Loa loa infection: an observational cohort study. The Lancet. Infectious Diseases. PMID 31676244 DOI: 10.1016/S1473-3099(19)30554-7  0.311
2019 Bonne-Année S, Bush MC, Nutman TB. Differential Modulation of Human Innate Lymphoid Cell (ILC) Subsets by IL-10 and TGF-β. Scientific Reports. 9: 14305. PMID 31586075 DOI: 10.1038/S41598-019-50308-8  0.328
2019 Rajamanickam A, Munisankar S, Dolla C, Nutman TB, Babu S. Cytotoxic T-Lymphocyte-Associated Antigen 4 (CTLA-4) and Programmed Death 1 (PD-1) mediated regulation of mono- and dual functional CD4 and CD8 T-cell responses in a chronic helminth infection. Infection and Immunity. PMID 31570560 DOI: 10.1128/Iai.00469-19  0.395
2019 Flynn AF, Joyce MG, Taylor RT, Bennuru S, Lindrose AR, Sterling SL, Morris CP, Nutman TB, Mitre E. Intestinal UDP-glucuronosyltransferase as a potential target for the treatment and prevention of lymphatic filariasis. Plos Neglected Tropical Diseases. 13: e0007687. PMID 31513587 DOI: 10.1371/Journal.Pntd.0007687  0.334
2019 Gazzinelli-Guimaraes PH, de Queiroz Prado R, Ricciardi A, Bonne-Année S, Sciurba J, Karmele EP, Fujiwara RT, Nutman TB. Allergen presensitization drives an eosinophil-dependent arrest in lung-specific helminth development. The Journal of Clinical Investigation. 130. PMID 31380805 DOI: 10.1172/Jci127963  0.451
2019 Pilotte N, Maasch JRMA, Easton AV, Dahlstrom E, Nutman TB, Williams SA. Targeting a highly repeated germline DNA sequence for improved real-time PCR-based detection of Ascaris infection in human stool. Plos Neglected Tropical Diseases. 13: e0007593. PMID 31329586 DOI: 10.1371/Journal.Pntd.0007593  0.306
2019 Lehman B, Leal SM, Procop GW, O'Connell E, Shaik J, Nash TE, Nutman TB, Jones S, Braunthal S, Shah SN, Cruise MW, Mukhopadhyay S, Banzon J. Disseminated Metacestode Versteria Species Infection in Woman, Pennsylvania, USA. Emerging Infectious Diseases. 25: 1429-1431. PMID 31211937 DOI: 10.3201/Eid2507.190223  0.307
2019 Bennuru S, Oduro-Boateng G, Osigwe C, Del-Valle P, Golden A, Ogawa GM, Cama V, Lustigman S, Nutman TB. Integrating multiple biomarkers to increase sensitivity for the detection of Onchocerca volvulus infection. The Journal of Infectious Diseases. PMID 31201416 DOI: 10.1093/Infdis/Jiz307  0.386
2019 Small ST, Labbé F, Coulibaly YI, Nutman TB, King CL, Serre D, Zimmerman PA. Human Migration and the Spread of the Nematode Parasite Wuchereria bancrofti. Molecular Biology and Evolution. PMID 31077328 DOI: 10.1093/Molbev/Msz116  0.311
2019 Easton AV, Quiñones M, Vujkovic-Cvijin I, Oliveira RG, Kepha S, Odiere MR, Anderson RM, Belkaid Y, Nutman TB. The Impact of Anthelmintic Treatment on Human Gut Microbiota Based on Cross-Sectional and Pre- and Postdeworming Comparisons in Western Kenya. Mbio. 10. PMID 31015324 DOI: 10.1128/Mbio.00519-19  0.335
2019 Nana-Djeunga HC, Fossuo-Thotchum F, Pion SD, Chesnais CB, Kubofcik J, Mackenzie CD, Klion AD, Boussinesq M, Nutman TB, Kamgno J. Loa loa microfilariae in skin snips: consequences for onchocerciasis monitoring and evaluation in L. loa endemic areas. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 30861060 DOI: 10.1093/Cid/Ciz172  0.304
2019 Showler AJ, Kubofcik J, Ricciardi A, Nutman TB. Differences in the Clinical and Laboratory Features of Imported Onchocerciasis in Endemic Individuals and Temporary Residents. The American Journal of Tropical Medicine and Hygiene. PMID 30761981 DOI: 10.4269/Ajtmh.18-0757  0.42
2019 Krolewiecki A, Nutman TB. Strongyloidiasis: A Neglected Tropical Disease. Infectious Disease Clinics of North America. 33: 135-151. PMID 30712758 DOI: 10.1016/J.Idc.2018.10.006  0.43
2019 Coelho CH, Gazzinelli-Guimaraes PH, Howard J, Barnafo E, Alani NAH, Muratova O, McCormack A, Kelnhofer E, Urban JF, Narum DL, Anderson C, Langhorne J, Nutman TB, Duffy PE. Chronic helminth infection does not impair immune response to malaria transmission blocking vaccine Pfs230D1-EPA/Alhydrogel® in mice. Vaccine. PMID 30685251 DOI: 10.1016/J.Vaccine.2019.01.027  0.394
2019 Rajamanickam A, Munisankar S, Bhootra Y, Dolla CK, Nutman TB, Babu S. Coexistent Helminth Infection-Mediated Modulation of Chemokine Responses in Latent Tuberculosis. Journal of Immunology (Baltimore, Md. : 1950). PMID 30651341 DOI: 10.4049/Jimmunol.1801190  0.409
2018 Patton JB, Bennuru S, Eberhard ML, Hess JA, Torigian A, Lustigman S, Nutman TB, Abraham D. Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum. Plos Neglected Tropical Diseases. 12: e0006977. PMID 30540742 DOI: 10.1371/Journal.Pntd.0006977  0.338
2018 de Ruiter K, Tahapary DL, Sartono E, Nutman TB, Smit JWA, Koenderman L, Supali T, Yazdanbakhsh M. The effect of helminths on granulocyte activation: a cluster-randomized placebo-controlled trial in Indonesia. The Journal of Infectious Diseases. PMID 30452713 DOI: 10.1093/Infdis/Jiy665  0.341
2018 Gazzinelli-Guimaraes PH, Nutman TB. Helminth parasites and immune regulation. F1000research. 7. PMID 30416709 DOI: 10.12688/F1000Research.15596.1  0.401
2018 Rajamanickam A, Munisankar S, Bhootra Y, Dolla C, Thiruvengadam K, Nutman TB, Babu S. Metabolic consequences of concomitant Strongyloides stercoralis infection in Type 2 diabetes mellitus. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 30407548 DOI: 10.1093/Cid/Ciy935  0.301
2018 Rajamanickam A, Munisankar S, Bhootra Y, Dolla C, Nutman TB, Babu S. Elevated Systemic and Parasite-Antigen Stimulated Levels of Type III IFNs in a Chronic Helminth Infection and Reversal Following Anthelmintic Treatment. Frontiers in Immunology. 9: 2353. PMID 30405603 DOI: 10.3389/Fimmu.2018.02353  0.422
2018 Mackenzie CD, Al-Kubati AS, Al-Qubati Y, Behan-Braman A, Kubofcik J, Hopkins A, Nutman TB. A Serological Survey of Human Onchocerciasis in Yemen. The American Journal of Tropical Medicine and Hygiene. PMID 30084341 DOI: 10.4269/Ajtmh.18-0051  0.314
2018 O'Connell EM, Mitchell T, Papaiakovou M, Pilotte N, Lee D, Weinberg M, Sakulrak P, Tongsukh D, Oduro-Boateng G, Harrison S, Williams SA, Stauffer WM, Nutman TB. Ancylostoma ceylanicum Hookworm in Myanmar Refugees, Thailand, 2012-2015. Emerging Infectious Diseases. 24. PMID 30014834 DOI: 10.3201/Eid2408.180280  0.363
2018 Rajamanickam A, Munisankar S, Bhootra Y, Dolla CK, Thiruvengadam K, Nutman TB, Babu S. Altered levels of memory T cell subsets and common γc cytokines in Strongyloides stercoralis infection and partial reversal following anthelmintic treatment. Plos Neglected Tropical Diseases. 12: e0006481. PMID 29795573 DOI: 10.1371/Journal.Pntd.0006481  0.391
2018 Dolo H, Coulibaly YI, Kelly-Hope L, Konate S, Dembele B, Coulibaly SY, Sanogo D, Soumaoro L, Coulibaly ME, Doumbia SS, Diallo AA, Traore SF, Colebunders R, Nutman TB, Klion AD. Factors Associated with Microfilaremia in an Endemic Area of Mali. The American Journal of Tropical Medicine and Hygiene. PMID 29714157 DOI: 10.4269/Ajtmh.17-0902  0.334
2018 Narasimhan PB, Akabas L, Tariq S, Huda N, Bennuru S, Sabzevari H, Hofmeister R, Nutman TB, Tolouei Semnani R. Similarities and differences between helminth parasites and cancer cell lines in shaping human monocytes: Insights into parallel mechanisms of immune evasion. Plos Neglected Tropical Diseases. 12: e0006404. PMID 29668679 DOI: 10.1371/Journal.Pntd.0006404  0.327
2018 Kwan JL, Seitz AE, Fried M, Lee KL, Metenou S, Morrison R, Kabyemela E, Nutman TB, Prevots DR, Duffy PE. Seroepidemiology of helminths and the association with severe malaria among infants and young children in Tanzania. Plos Neglected Tropical Diseases. 12: e0006345. PMID 29579050 DOI: 10.1371/Journal.Pntd.0006345  0.352
2018 Rajamanickam A, Munisankar S, Bhootra Y, Dolla CK, Nutman TB, Babu S. Elevated Systemic Levels of Eosinophil, Neutrophil, and Mast Cell Granular Proteins inInfection that Diminish following Treatment. Frontiers in Immunology. 9: 207. PMID 29479356 DOI: 10.3389/Fimmu.2018.00207  0.385
2018 Sangare MB, Coulibaly YI, Coulibaly SY, Coulibaly ME, Traore B, Dicko I, Sissoko IM, Samake S, Traore SF, Nutman TB, Valenzuela JG, Faye O, Kamhawi S, Oliveira F, Semnani RT, et al. A cross-sectional study of the filarial and Leishmania co-endemicity in two ecologically distinct settings in Mali. Parasites & Vectors. 11: 18. PMID 29310700 DOI: 10.1186/S13071-017-2531-8  0.312
2017 Mitchell T, Lee D, Weinberg M, Phares C, James N, Amornpaisarnloet K, Aumpipat L, Cooley G, Davies A, Tin Shwe VD, Gajdadziev V, Gorbacheva O, Khwan-Niam C, Klosovsky A, Madilokkowit W, ... ... Nutman TB, et al. Impact of Enhanced Health Interventions for United States-Bound Refugees: Evaluating Best Practices in Migration Health. The American Journal of Tropical Medicine and Hygiene. PMID 29260657 DOI: 10.4269/Ajtmh.17-0725  0.334
2017 Bennuru S, O'Connell EM, Drame PM, Nutman TB. Mining Filarial Genomes for Diagnostic and Therapeutic Targets. Trends in Parasitology. PMID 29031509 DOI: 10.1016/J.Pt.2017.09.003  0.337
2017 Anuradha R, Munisankar S, Bhootra Y, Dolla C, Kumaran P, Nutman TB, Babu S. Modulation of CD4(+) and CD8(+) T cell function and cytokine responses in Strongyloides stercoralis infection by IL-27 and IL-37. Infection and Immunity. PMID 28874444 DOI: 10.1128/Iai.00500-17  0.391
2017 Pedram B, Pasquetto V, Drame PM, Ji Y, Gonzalez-Moa MJ, Baldwin RK, Nutman TB, Biamonte MA. A novel rapid test for detecting antibody responses to Loa loa infections. Plos Neglected Tropical Diseases. 11: e0005741. PMID 28749939 DOI: 10.1371/Journal.Pntd.0005741  0.389
2017 Chatterjee S, Talaat KR, van Seventer EE, Feng CG, Scott AL, Jedlicka A, Dziedzic A, Nutman TB. Mycobacteria induce TPL-2 mediated IL-10 in IL-4-generated alternatively activated macrophages. Plos One. 12: e0179701. PMID 28658262 DOI: 10.1371/Journal.Pone.0179701  0.408
2017 Drame PM, Bennuru S, Nutman TB. Discovery of specific antigens that can predict microfilarial intensity in Loa loa infection. Journal of Clinical Microbiology. PMID 28637911 DOI: 10.1128/Jcm.00513-17  0.351
2017 Johnson T, Nutman T, Dowell S, Nath A. Closing the Loop between Nodding Syndrome and Onchocerca Infection. Trends in Parasitology. PMID 28596063 DOI: 10.1016/J.Pt.2017.05.002  0.327
2017 Easton AV, Oliveira RG, Walker M, O'Connell EM, Njenga SM, Mwandawiro CS, Webster JP, Nutman TB, Anderson RM. Sources of variability in the measurement of Ascaris lumbricoides infection intensity by Kato-Katz and qPCR. Parasites & Vectors. 10: 256. PMID 28545561 DOI: 10.1186/S13071-017-2164-Y  0.301
2017 Arnold BF, van der Laan MJ, Hubbard AE, Steel C, Kubofcik J, Hamlin KL, Moss DM, Nutman TB, Priest JW, Lammie PJ. Measuring changes in transmission of neglected tropical diseases, malaria, and enteric pathogens from quantitative antibody levels. Plos Neglected Tropical Diseases. 11: e0005616. PMID 28542223 DOI: 10.1371/Journal.Pntd.0005616  0.311
2017 Bonne-Année S, Nutman TB. Human innate lymphoid cells (ILCs) in filarial infections. Parasite Immunology. PMID 28504838 DOI: 10.1111/Pim.12442  0.445
2017 Anuradha R, Munisankar S, Bhootra Y, Dolla C, Kumaran P, Nutman TB, Babu S. Modulation of Mycobacterium tuberculosis-specific humoral immune responses is associated with Strongyloides stercoralis co-infection. Plos Neglected Tropical Diseases. 11: e0005569. PMID 28459817 DOI: 10.1371/Journal.Pntd.0005569  0.418
2017 Herrick JA, Legrand F, Gounoue R, Nchinda G, Montavon C, Bopda J, Tchana SM, Ondigui BE, Nguluwe K, Fay MP, Makiya M, Metenou S, Nutman TB, Kamgno J, Klion AD. Posttreatment Reactions After Single-Dose Diethylcarbamazine or Ivermectin in Subjects With Loa loa Infection. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 28329346 DOI: 10.1093/Cid/Cix016  0.303
2017 Johnson TP, Tyagi R, Lee PR, Lee MH, Johnson KR, Kowalak J, Elkahloun A, Medynets M, Hategan A, Kubofcik J, Sejvar J, Ratto J, Bunga S, Makumbi I, Aceng JR, ... Nutman TB, et al. Nodding syndrome may be an autoimmune reaction to the parasitic worm Onchocerca volvulus. Science Translational Medicine. 9. PMID 28202777 DOI: 10.1126/Scitranslmed.Aaf6953  0.309
2017 Bennuru S, Lustigman S, Abraham D, Nutman TB. Metabolite profiling of infection-associated metabolic markers of onchocerciasis. Molecular and Biochemical Parasitology. PMID 28188804 DOI: 10.1016/J.Molbiopara.2017.01.008  0.313
2017 Anuradha R, Munisankar S, Bhootra Y, Dolla C, Kumaran P, Nutman TB, Babu S. Anthelmintic therapy modifies the systemic and mycobacterial-antigen-stimulated cytokine profile in helminth-latent Mycobacterium tuberculosis co-infection. Infection and Immunity. PMID 28167672 DOI: 10.1128/Iai.00973-16  0.393
2017 Lin AA, Nutman TB. IL-10 Differentially Affects IgE and IgG4 Production Through Distinct Mechanisms The Journal of Allergy and Clinical Immunology. 139. DOI: 10.1016/J.Jaci.2016.12.094  0.309
2016 Bennuru S, Cotton JA, Ribeiro JM, Grote A, Harsha B, Holroyd N, Mhashilkar A, Molina DM, Randall AZ, Shandling AD, Unnasch TR, Ghedin E, Berriman M, Lustigman S, Nutman TB. Stage-Specific Transcriptome and Proteome Analyses of the Filarial Parasite Onchocerca volvulus and Its Wolbachia Endosymbiont. Mbio. 7. PMID 27881553 DOI: 10.1128/Mbio.02028-16  0.338
2016 Rajamanickam A, Munisankar S, Bhootra Y, Dolla C, Nutman TB, Babu S. Microbial translocation associated with an acute phase response and elevations in MMP-1, HO-1 and pro-inflammatory cytokines in Strongyloides stercoralis infection. Infection and Immunity. PMID 27821584 DOI: 10.1128/Iai.00772-16  0.38
2016 Pion SD, Montavon C, Chesnais CB, Kamgno J, Wanji S, Klion AD, Nutman TB, Boussinesq M. Positivity of Antigen Tests Used for Diagnosis of Lymphatic Filariasis in Individuals Without Wuchereria bancrofti Infection But with High Loa loa Microfilaremia. The American Journal of Tropical Medicine and Hygiene. PMID 27729568 DOI: 10.4269/Ajtmh.16-0547  0.327
2016 Santiago HC, Nutman TB. Human Helminths and Allergic Disease: The Hygiene Hypothesis and Beyond. The American Journal of Tropical Medicine and Hygiene. PMID 27573628 DOI: 10.4269/Ajtmh.16-0348  0.425
2016 Gazzinelli-Guimarães PH, Bonne-Année S, Fujiwara RT, Santiago HC, Nutman TB. Allergic Sensitization Underlies Hyperreactive Antigen-Specific CD4+ T Cell Responses in Coincident Filarial Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 27566825 DOI: 10.4049/Jimmunol.1600829  0.39
2016 Babu S, Nutman TB. Helminth-Tuberculosis Co-infection: An Immunologic Perspective. Trends in Immunology. PMID 27501916 DOI: 10.1016/J.It.2016.07.005  0.421
2016 Santiago Hda C, Nutman TB. Role in Allergic Diseases of Immunological Cross-Reactivity between Allergens and Homologues of Parasite Proteins. Critical Reviews in Immunology. 36: 1-11. PMID 27480900 DOI: 10.1615/Critrevimmunol.2016016545  0.427
2016 Hickey BW, Lumsden JM, Reyes S, Sedegah M, Hollingdale MR, Freilich DA, Luke TC, Charoenvit Y, Goh LM, Berzins MP, Bebris L, Sacci JB, De La Vega P, Wang R, Ganeshan H, ... ... Nutman TB, et al. Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: safety, tolerability, protective efficacy and humoral immunogenicity. Malaria Journal. 15: 377. PMID 27448805 DOI: 10.1186/S12936-016-1435-Y  0.352
2016 Narasimhan PB, Bennuru S, Meng Z, Cotton RN, Elliott KR, Ganesan S, McDonald-Fleming R, Veenstra TD, Nutman TB, Semnani RT. Microfilariae of Brugia malayi inhibit the mTOR pathway and induce autophagy in human dendritic cells. Infection and Immunity. PMID 27297394 DOI: 10.1128/Iai.00174-16  0.322
2016 Nutman TB. Human infection with Strongyloides stercoralis and other related Strongyloides species. Parasitology. 1-11. PMID 27181117 DOI: 10.1017/S0031182016000834  0.434
2016 Drame PM, Montavon C, Pion SD, Kubofcik J, Fay MP, Nutman TB. Molecular Epidemiology of Blood-Borne Human Parasites in a Loa loa-, Mansonella perstans-, and Plasmodium falciparum-Endemic Region of Cameroon. The American Journal of Tropical Medicine and Hygiene. PMID 27044568 DOI: 10.4269/Ajtmh.15-0746  0.381
2016 Clark CE, Fay MP, Chico ME, Sandoval CA, Vaca MG, Boyd A, Cooper PJ, Nutman TB. Maternal helminth infection is associated with higher infant IgA titers to orally administered vaccines. The Journal of Infectious Diseases. PMID 26908751 DOI: 10.1093/Infdis/Jiw066  0.604
2016 Easton AV, Oliveira RG, O'Connell EM, Kepha S, Mwandawiro CS, Njenga SM, Kihara JH, Mwatele C, Odiere MR, Brooker SJ, Webster JP, Anderson RM, Nutman TB. Multi-parallel qPCR provides increased sensitivity and diagnostic breadth for gastrointestinal parasites of humans: field-based inferences on the impact of mass deworming. Parasites & Vectors. 9: 38. PMID 26813411 DOI: 10.1186/S13071-016-1314-Y  0.356
2016 Anuradha R, Munisankar S, Bhootra Y, Jagannathan J, Dolla C, Kumaran P, Nutman TB, Babu S. IL-10- and TGFβ-mediated Th9 Responses in a Human Helminth Infection. Plos Neglected Tropical Diseases. 10: e0004317. PMID 26730582 DOI: 10.1371/Journal.Pntd.0004317  0.438
2016 Lin AA, Nutman TB. IL-10 Differentially Regulates IgE and IgG4 Production through Indirect Effects on Naïve B Cells The Journal of Allergy and Clinical Immunology. 137. DOI: 10.1016/J.Jaci.2015.12.755  0.311
2015 Drame PM, Meng Z, Bennuru S, Herrick JA, Veenstra TD, Nutman TB. Identification and Validation of Loa loa Microfilaria-Specific Biomarkers: a Rational Design Approach Using Proteomics and Novel Immunoassays. Mbio. 7. PMID 26884435 DOI: 10.1128/Mbio.02132-15  0.365
2015 Anuradha R, Munisankar S, Bhootra Y, Jagannathan J, Dolla C, Kumaran P, Shen K, Nutman TB, Babu S. Systemic cytokine profiles in Strongyloides stercoralis infection and alterations following treatment. Infection and Immunity. PMID 26597982 DOI: 10.1128/Iai.01354-15  0.37
2015 Tosh KW, Mittereder L, Bonne-Annee S, Hieny S, Nutman TB, Singer SM, Sher A, Jankovic D. The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion. Journal of Immunology (Baltimore, Md. : 1950). PMID 26597011 DOI: 10.4049/Jimmunol.1501558  0.407
2015 George PJ, Pavan Kumar N, Jaganathan J, Dolla C, Kumaran P, Nair D, Banurekha VV, Shen K, Nutman TB, Babu S. Modulation of pro- and anti-inflammatory cytokines in active and latent tuberculosis by coexistent Strongyloides stercoralis infection. Tuberculosis (Edinburgh, Scotland). PMID 26542223 DOI: 10.1016/J.Tube.2015.09.009  0.431
2015 Anuradha R, Munisankar S, Dolla C, Kumaran P, Nutman TB, Babu S. Modulation of CD4+ and CD8+ T-Cell Function by Interleukin 19 and Interleukin 24 During Filarial Infections. The Journal of Infectious Diseases. PMID 26486636 DOI: 10.1093/Infdis/Jiv497  0.38
2015 Kumar NP, Moideen K, Banurekha VV, Nair D, Sridhar R, Nutman TB, Babu S. IL-27 and TGFβ mediated expansion of Th1 and adaptive regulatory T cells expressing IL-10 correlates with bacterial burden and disease severity in pulmonary tuberculosis. Immunity, Inflammation and Disease. 3: 289-99. PMID 26417443 DOI: 10.1002/Iid3.68  0.346
2015 Boyd A, Killoran K, Mitre E, Nutman TB. Pleural cavity type 2 innate lymphoid cells precede Th2 expansion in murine Litomosoides sigmodontis infection. Experimental Parasitology. 159: 118-126. PMID 26394284 DOI: 10.1016/J.Exppara.2015.09.006  0.688
2015 Morris CP, Bennuru S, Kropp LE, Zweben JA, Meng Z, Taylor RT, Chan K, Veenstra TD, Nutman TB, Mitre E. A Proteomic Analysis of the Body Wall, Digestive Tract, and Reproductive Tract of Brugia malayi. Plos Neglected Tropical Diseases. 9: e0004054. PMID 26367142 DOI: 10.1371/Journal.Pntd.0004054  0.311
2015 Yooseph S, Kirkness EF, Tran TM, Harkins DM, Jones MB, Torralba MG, O'Connell E, Nutman TB, Doumbo S, Doumbo OK, Traore B, Crompton PD, Nelson KE. Stool microbiota composition is associated with the prospective risk of Plasmodium falciparum infection. Bmc Genomics. 16: 631. PMID 26296559 DOI: 10.1186/S12864-015-1819-3  0.348
2015 Anuradha R, Munisankar S, Dolla C, Kumaran P, Nutman TB, Babu S. Parasite Antigen-Specific Regulation of Th1, Th2, and Th17 Responses in Strongyloides stercoralis Infection. Journal of Immunology (Baltimore, Md. : 1950). 195: 2241-50. PMID 26202988 DOI: 10.4049/Jimmunol.1500745  0.382
2015 Steel C, Golden A, Stevens E, Yokobe L, Domingo GJ, de los Santos T, Nutman TB. Rapid Point-of-Contact Tool for Mapping and Integrated Surveillance of Wuchereria bancrofti and Onchocerca volvulus Infection. Clinical and Vaccine Immunology : Cvi. 22: 896-901. PMID 26018537 DOI: 10.1128/Cvi.00227-15  0.362
2015 D'Ambrosio MV, Bakalar M, Bennuru S, Reber C, Skandarajah A, Nilsson L, Switz N, Kamgno J, Pion S, Boussinesq M, Nutman TB, Fletcher DA. Point-of-care quantification of blood-borne filarial parasites with a mobile phone microscope. Science Translational Medicine. 7: 286re4. PMID 25947164 DOI: 10.1126/Scitranslmed.Aaa3480  0.323
2015 Buonfrate D, Sequi M, Mejia R, Cimino RO, Krolewiecki AJ, Albonico M, Degani M, Tais S, Angheben A, Requena-Mendez A, Muñoz J, Nutman TB, Bisoffi Z. Accuracy of five serologic tests for the follow up of Strongyloides stercoralis infection. Plos Neglected Tropical Diseases. 9: e0003491. PMID 25668740 DOI: 10.1371/Journal.Pntd.0003491  0.374
2015 Chatterjee S, Clark CE, Lugli E, Roederer M, Nutman TB. Filarial infection modulates the immune response to Mycobacterium tuberculosis through expansion of CD4+ IL-4 memory T cells. Journal of Immunology (Baltimore, Md. : 1950). 194: 2706-14. PMID 25667413 DOI: 10.4049/Jimmunol.1402718  0.387
2015 Chatterjee S, Nutman TB. Helminth-induced immune regulation: implications for immune responses to tuberculosis. Plos Pathogens. 11: e1004582. PMID 25632943 DOI: 10.1371/Journal.Ppat.1004582  0.431
2015 Jang JC, Chen G, Wang SH, Barnes MA, Chung JI, Camberis M, Le Gros G, Cooper PJ, Steel C, Nutman TB, Lazar MA, Nair MG. Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. Plos Pathogens. 11: e1004579. PMID 25568944 DOI: 10.1371/Journal.Ppat.1004579  0.447
2015 Cotton RN, McDonald-Fleming R, Boyd A, Spates K, Nutman TB, Tolouei Semnani R. Brugia malayi infective larvae fail to activate Langerhans cells and dermal dendritic cells in human skin. Parasite Immunology. 37: 79-91. PMID 25545218 DOI: 10.1111/Pim.12169  0.646
2015 Santiago Hda C, Ribeiro-Gomes FL, Bennuru S, Nutman TB. Helminth infection alters IgE responses to allergens structurally related to parasite proteins. Journal of Immunology (Baltimore, Md. : 1950). 194: 93-100. PMID 25404363 DOI: 10.4049/Jimmunol.1401638  0.413
2015 Kumar NP, Sridhar R, Nair D, Banurekha VV, Nutman TB, Babu S. Type 2 diabetes mellitus is associated with altered CD8(+) T and natural killer cell function in pulmonary tuberculosis. Immunology. 144: 677-86. PMID 25363329 DOI: 10.1111/Imm.12421  0.347
2015 Herrick JA, Metenou S, Makiya MA, Taylar-Williams CA, Law MA, Klion AD, Nutman TB. Eosinophil-associated processes underlie differences in clinical presentation of loiasis between temporary residents and those indigenous to Loa-endemic areas. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 60: 55-63. PMID 25234520 DOI: 10.1093/Cid/Ciu723  0.41
2015 Nutman TB. Looking beyond the induction of Th2 responses to explain immunomodulation by helminths Parasite Immunology. 37: 304-313. DOI: 10.1111/Pim.12194  0.439
2014 George PJ, Kumar NP, Sridhar R, Hanna LE, Nair D, Banurekha VV, Nutman TB, Babu S. Coincident helminth infection modulates systemic inflammation and immune activation in active pulmonary tuberculosis. Plos Neglected Tropical Diseases. 8: e3289. PMID 25375117 DOI: 10.1371/Journal.Pntd.0003289  0.377
2014 Kumar NP, Sridhar R, Hanna LE, Banurekha VV, Nutman TB, Babu S. Decreased frequencies of circulating CD4⁺ T follicular helper cells associated with diminished plasma IL-21 in active pulmonary tuberculosis. Plos One. 9: e111098. PMID 25343703 DOI: 10.1371/Journal.Pone.0111098  0.4
2014 Boyd A, Ribeiro JM, Nutman TB. Human CD117 (cKit)+ innate lymphoid cells have a discrete transcriptional profile at homeostasis and are expanded during filarial infection. Plos One. 9: e108649. PMID 25255226 DOI: 10.1371/Journal.Pone.0108649  0.678
2014 Anuradha R, George PJ, Kumaran P, Nutman TB, Babu S. Interleukin-10- and transforming growth factor β-independent regulation of CD8⁺ T cells expressing type 1 and type 2 cytokines in human lymphatic filariasis. Clinical and Vaccine Immunology : Cvi. 21: 1620-7. PMID 25253667 DOI: 10.1128/Cvi.00598-14  0.397
2014 Bennuru S, Pion SD, Kamgno J, Wanji S, Nutman TB. Repurposed automated handheld counter as a point-of-care tool to identify individuals 'at risk' of serious post-ivermectin encephalopathy. Plos Neglected Tropical Diseases. 8: e3180. PMID 25232954 DOI: 10.1371/Journal.Pntd.0003180  0.334
2014 Tallon LJ, Liu X, Bennuru S, Chibucos MC, Godinez A, Ott S, Zhao X, Sadzewicz L, Fraser CM, Nutman TB, Dunning Hotopp JC. Single molecule sequencing and genome assembly of a clinical specimen of Loa loa, the causative agent of loiasis. Bmc Genomics. 15: 788. PMID 25217238 DOI: 10.1186/1471-2164-15-788  0.301
2014 George PJ, Anuradha R, Kumar NP, Sridhar R, Banurekha VV, Nutman TB, Babu S. Helminth infections coincident with active pulmonary tuberculosis inhibit mono- and multifunctional CD4+ and CD8+ T cell responses in a process dependent on IL-10. Plos Pathogens. 10: e1004375. PMID 25211342 DOI: 10.1371/Journal.Ppat.1004375  0.43
2014 Doumbo S, Tran TM, Sangala J, Li S, Doumtabe D, Kone Y, Traoré A, Bathily A, Sogoba N, Coulibaly ME, Huang CY, Ongoiba A, Kayentao K, Diallo M, Dramane Z, ... Nutman TB, et al. Co-infection of long-term carriers of Plasmodium falciparum with Schistosoma haematobium enhances protection from febrile malaria: a prospective cohort study in Mali. Plos Neglected Tropical Diseases. 8: e3154. PMID 25210876 DOI: 10.1371/Journal.Pntd.0003154  0.415
2014 Tolouei Semnani R, Moore V, Bennuru S, McDonald-Fleming R, Ganesan S, Cotton R, Anuradha R, Babu S, Nutman TB. Human monocyte subsets at homeostasis and their perturbation in numbers and function in filarial infection. Infection and Immunity. 82: 4438-46. PMID 25114121 DOI: 10.1128/Iai.01973-14  0.393
2014 Pak BJ, Vasquez-Camargo F, Kalinichenko E, Chiodini PL, Nutman TB, Tanowitz HB, McAuliffe I, Wilkins P, Smith PT, Ward BJ, Libman MD, Ndao M. Development of a rapid serological assay for the diagnosis of strongyloidiasis using a novel diffraction-based biosensor technology. Plos Neglected Tropical Diseases. 8: e3002. PMID 25102174 DOI: 10.1371/Journal.Pntd.0003002  0.41
2014 Mounsey K, Kearns T, Rampton M, Llewellyn S, King M, Holt D, Currie BJ, Andrews R, Nutman T, McCarthy J. Use of dried blood spots to define antibody response to the Strongyloides stercoralis recombinant antigen NIE. Acta Tropica. 138: 78-82. PMID 25051188 DOI: 10.1016/J.Actatropica.2014.07.007  0.321
2014 Kumar NP, Sridhar R, Hanna LE, Banurekha VV, Jawahar MS, Nutman TB, Babu S. Altered CD8(+) T cell frequency and function in tuberculous lymphadenitis. Tuberculosis (Edinburgh, Scotland). 94: 482-93. PMID 25027793 DOI: 10.1016/J.Tube.2014.06.007  0.356
2014 Kumar NP, George PJ, Kumaran P, Dolla CK, Nutman TB, Babu S. Diminished systemic and antigen-specific type 1, type 17, and other proinflammatory cytokines in diabetic and prediabetic individuals with latent Mycobacterium tuberculosis infection. The Journal of Infectious Diseases. 210: 1670-8. PMID 24907382 DOI: 10.1093/Infdis/Jiu329  0.357
2014 Kamuyu G, Bottomley C, Mageto J, Lowe B, Wilkins PP, Noh JC, Nutman TB, Ngugi AK, Odhiambo R, Wagner RG, Kakooza-Mwesige A, Owusu-Agyei S, Ae-Ngibise K, Masanja H, Osier FH, et al. Exposure to multiple parasites is associated with the prevalence of active convulsive epilepsy in sub-Saharan Africa. Plos Neglected Tropical Diseases. 8: e2908. PMID 24875312 DOI: 10.1371/Journal.Pntd.0002908  0.353
2014 Anuradha R, George PJ, Chandrasekaran V, Kumaran PP, Nutman TB, Babu S. Interleukin 1 (IL-1)- and IL-23-mediated expansion of filarial antigen-specific Th17 and Th22 cells in filarial lymphedema. Clinical and Vaccine Immunology : Cvi. 21: 960-5. PMID 24807054 DOI: 10.1128/Cvi.00257-14  0.404
2014 Metenou S, Coulibaly YI, Sturdevant D, Dolo H, Diallo AA, Soumaoro L, Coulibaly ME, Kanakabandi K, Porcella SF, Klion AD, Nutman TB. Highly heterogeneous, activated, and short-lived regulatory T cells during chronic filarial infection. European Journal of Immunology. 44: 2036-47. PMID 24737144 DOI: 10.1002/Eji.201444452  0.402
2014 Chatterjee S, Kolappan C, Subramani R, Gopi PG, Chandrasekaran V, Fay MP, Babu S, Kumaraswami V, Nutman TB. Incidence of active pulmonary tuberculosis in patients with coincident filarial and/or intestinal helminth infections followed longitudinally in South India. Plos One. 9: e94603. PMID 24728010 DOI: 10.1371/Journal.Pone.0094603  0.369
2014 Anuradha R, George PJ, Hanna LE, Kumaran P, Chandrasekaran V, Nutman TB, Babu S. Expansion of parasite-specific CD4+ and CD8+ T cells expressing IL-10 superfamily cytokine members and their regulation in human lymphatic filariasis. Plos Neglected Tropical Diseases. 8: e2762. PMID 24699268 DOI: 10.1371/Journal.Pntd.0002762  0.377
2014 Drame PM, Fink DL, Kamgno J, Herrick JA, Nutman TB. Loop-mediated isothermal amplification for rapid and semiquantitative detection of Loa loa infection. Journal of Clinical Microbiology. 52: 2071-7. PMID 24696020 DOI: 10.1128/Jcm.00525-14  0.349
2014 Anuradha R, George PJ, Hanna LE, Chandrasekaran V, Kumaran PP, Nutman TB, Babu S. Parasite-antigen driven expansion of IL-5(-) and IL-5(+) Th2 human subpopulations in lymphatic filariasis and their differential dependence on IL-10 and TGFβ. Plos Neglected Tropical Diseases. 8: e2658. PMID 24498448 DOI: 10.1371/Journal.Pntd.0002658  0.341
2014 Spencer SP, Wilhelm C, Yang Q, Hall JA, Bouladoux N, Boyd A, Nutman TB, Urban JF, Wang J, Ramalingam TR, Bhandoola A, Wynn TA, Belkaid Y. Adaptation of innate lymphoid cells to a micronutrient deficiency promotes type 2 barrier immunity. Science (New York, N.Y.). 343: 432-7. PMID 24458645 DOI: 10.1126/Science.1247606  0.64
2014 Bisoffi Z, Buonfrate D, Sequi M, Mejia R, Cimino RO, Krolewiecki AJ, Albonico M, Gobbo M, Bonafini S, Angheben A, Requena-Mendez A, Muñoz J, Nutman TB. Diagnostic accuracy of five serologic tests for Strongyloides stercoralis infection. Plos Neglected Tropical Diseases. 8: e2640. PMID 24427320 DOI: 10.1371/Journal.Pntd.0002640  0.335
2014 Babu S, Nutman TB. Immunology of lymphatic filariasis Parasite Immunology. 36: 338-346. PMID 24134686 DOI: 10.1111/Pim.12081  0.432
2014 Kumar NP, Sridhar R, Banurekha VV, Jawahar MS, Nutman TB, Babu S. Role of myeloid derived suppressor cells in tuberculosis infection and disease Bmc Infectious Diseases. 14. DOI: 10.1186/1471-2334-14-S3-O18  0.418
2014 Thamwiwat A, Mejia R, Nutman TB, Bates JT. Strongyloidiasis as a Cause of Chronic Diarrhea, Identified Using Next-Generation Strongyloides stercoralis-Specific Immunoassays Current Tropical Medicine Reports. 1: 145-147. DOI: 10.1007/S40475-014-0026-7  0.414
2013 Metenou S, Nutman TB. Regulatory T cell subsets in filarial infection and their function. Frontiers in Immunology. 4: 305. PMID 24137161 DOI: 10.3389/Fimmu.2013.00305  0.448
2013 Nutman TB. Insights into the pathogenesis of disease in human lymphatic filariasis. Lymphatic Research and Biology. 11: 144-8. PMID 24044755 DOI: 10.1089/Lrb.2013.0021  0.38
2013 Coulibaly YI, Dembele B, Diallo AA, Kristensen S, Konate S, Dolo H, Dicko I, Sangare MB, Keita F, Boatin BA, Traore AK, Nutman TB, Klion AD, Touré YT, Traore SF. Wuchereria bancrofti transmission pattern in southern Mali prior to and following the institution of mass drug administration. Parasites & Vectors. 6: 247. PMID 23981378 DOI: 10.1186/1756-3305-6-247  0.309
2013 Golden A, Steel C, Yokobe L, Jackson E, Barney R, Kubofcik J, Peck R, Unnasch TR, Nutman TB, de los Santos T, Domingo GJ. Extended result reading window in lateral flow tests detecting exposure to Onchocerca volvulus: a new technology to improve epidemiological surveillance tools. Plos One. 8: e69231. PMID 23935960 DOI: 10.1371/Journal.Pone.0069231  0.349
2013 Anuradha R, George PJ, Hanna LE, Chandrasekaran V, Kumaran P, Nutman TB, Babu S. IL-4-, TGF-β-, and IL-1-dependent expansion of parasite antigen-specific Th9 cells is associated with clinical pathology in human lymphatic filariasis. Journal of Immunology (Baltimore, Md. : 1950). 191: 2466-73. PMID 23913964 DOI: 10.4049/Jimmunol.1300911  0.391
2013 Steel C, Golden A, Kubofcik J, LaRue N, de Los Santos T, Domingo GJ, Nutman TB. Rapid Wuchereria bancrofti-specific antigen Wb123-based IgG4 immunoassays as tools for surveillance following mass drug administration programs on lymphatic filariasis. Clinical and Vaccine Immunology : Cvi. 20: 1155-61. PMID 23740923 DOI: 10.1128/Cvi.00252-13  0.42
2013 Andrade BB, Pavan Kumar N, Mayer-Barber KD, Barber DL, Sridhar R, Rekha VV, Jawahar MS, Nutman TB, Sher A, Babu S. Plasma heme oxygenase-1 levels distinguish latent or successfully treated human tuberculosis from active disease. Plos One. 8: e62618. PMID 23671613 DOI: 10.1371/Journal.Pone.0062618  0.324
2013 George PJ, Anuradha R, Kumaran PP, Chandrasekaran V, Nutman TB, Babu S. Modulation of mycobacterial-specific Th1 and Th17 cells in latent tuberculosis by coincident hookworm infection. Journal of Immunology (Baltimore, Md. : 1950). 190: 5161-8. PMID 23576678 DOI: 10.4049/Jimmunol.1203311  0.434
2013 Mejia R, Vicuña Y, Broncano N, Sandoval C, Vaca M, Chico M, Cooper PJ, Nutman TB. A novel, multi-parallel, real-time polymerase chain reaction approach for eight gastrointestinal parasites provides improved diagnostic capabilities to resource-limited at-risk populations. The American Journal of Tropical Medicine and Hygiene. 88: 1041-7. PMID 23509117 DOI: 10.4269/Ajtmh.12-0726  0.315
2013 Pavan Kumar N, Anuradha R, Andrade BB, Suresh N, Ganesh R, Shankar J, Kumaraswami V, Nutman TB, Babu S. Circulating biomarkers of pulmonary and extrapulmonary tuberculosis in children. Clinical and Vaccine Immunology : Cvi. 20: 704-11. PMID 23486418 DOI: 10.1128/Cvi.00038-13  0.338
2013 Kumar NP, Sridhar R, Banurekha VV, Nair D, Jawahar MS, Nutman TB, Babu S. Expansion of pathogen-specific mono- and multifunctional Th1 and Th17 cells in multi-focal tuberculous lymphadenitis. Plos One. 8: e57123. PMID 23451159 DOI: 10.1371/Journal.Pone.0057123  0.31
2013 Boyd A, Bennuru S, Wang Y, Sanprasert V, Law M, Chaussabel D, Nutman TB, Semnani RT. Quiescent innate response to infective filariae by human Langerhans cells suggests a strategy of immune evasion. Infection and Immunity. 81: 1420-9. PMID 23429540 DOI: 10.1128/Iai.01301-12  0.659
2012 Nabha L, Krishnan S, Ramanathan R, Mejia R, Roby G, Sheikh V, McAuliffe I, Nutman T, Sereti I. Prevalence of Strongyloides stercoralis in an urban US AIDS cohort. Pathogens and Global Health. 106: 238-44. PMID 23265425 DOI: 10.1179/2047773212Y.0000000031  0.336
2012 Hamlin KL, Moss DM, Priest JW, Roberts J, Kubofcik J, Gass K, Streit TG, Nutman TB, Eberhard ML, Lammie PJ. Longitudinal monitoring of the development of antifilarial antibodies and acquisition of Wuchereria bancrofti in a highly endemic area of Haiti. Plos Neglected Tropical Diseases. 6: e1941. PMID 23236534 DOI: 10.1371/Journal.Pntd.0001941  0.332
2012 Steel C, Kubofcik J, Ottesen EA, Nutman TB. Antibody to the filarial antigen Wb123 reflects reduced transmission and decreased exposure in children born following single mass drug administration (MDA). Plos Neglected Tropical Diseases. 6: e1940. PMID 23236533 DOI: 10.1371/Journal.Pntd.0001940  0.376
2012 Kubofcik J, Fink DL, Nutman TB. Identification of Wb123 as an early and specific marker of Wuchereria bancrofti infection. Plos Neglected Tropical Diseases. 6: e1930. PMID 23236529 DOI: 10.1371/Journal.Pntd.0001930  0.391
2012 Dolo H, Coulibaly YI, Dembele B, Konate S, Coulibaly SY, Doumbia SS, Diallo AA, Soumaoro L, Coulibaly ME, Diakite SA, Guindo A, Fay MP, Metenou S, Nutman TB, Klion AD. Filariasis attenuates anemia and proinflammatory responses associated with clinical malaria: a matched prospective study in children and young adults. Plos Neglected Tropical Diseases. 6: e1890. PMID 23133692 DOI: 10.1371/Journal.Pntd.0001890  0.373
2012 George PJ, Anuradha R, Kumar NP, Kumaraswami V, Nutman TB, Babu S. Evidence of microbial translocation associated with perturbations in T cell and antigen-presenting cell homeostasis in hookworm infections. Plos Neglected Tropical Diseases. 6: e1830. PMID 23056659 DOI: 10.1371/Journal.Pntd.0001830  0.39
2012 Babu S, Nutman TB. Immunopathogenesis of lymphatic filarial disease. Seminars in Immunopathology. 34: 847-61. PMID 23053393 DOI: 10.1007/S00281-012-0346-4  0.403
2012 Santiago Hda C, Bennuru S, Ribeiro JM, Nutman TB. Structural differences between human proteins and aero- and microbial allergens define allergenicity. Plos One. 7: e40552. PMID 22815762 DOI: 10.1371/Journal.Pone.0040552  0.311
2012 Mejia R, Nutman TB. Screening, prevention, and treatment for hyperinfection syndrome and disseminated infections caused by Strongyloides stercoralis. Current Opinion in Infectious Diseases. 25: 458-63. PMID 22691685 DOI: 10.1097/Qco.0B013E3283551Dbd  0.362
2012 Anuradha R, George PJ, Pavan Kumar N, Fay MP, Kumaraswami V, Nutman TB, Babu S. Circulating microbial products and acute phase proteins as markers of pathogenesis in lymphatic filarial disease. Plos Pathogens. 8: e1002749. PMID 22685406 DOI: 10.1371/Journal.Ppat.1002749  0.402
2012 Santiago HC, LeeVan E, Bennuru S, Ribeiro-Gomes F, Mueller E, Wilson M, Wynn T, Garboczi D, Urban J, Mitre E, Nutman TB. Molecular mimicry between cockroach and helminth glutathione S-transferases promotes cross-reactivity and cross-sensitization. The Journal of Allergy and Clinical Immunology. 130: 248-56.e9. PMID 22541242 DOI: 10.1016/J.Jaci.2012.02.045  0.341
2012 Mejia R, Booth GS, Fedorko DP, Hsieh MM, Khuu HM, Klein HG, Mu J, Fahle G, Nutman TB, Su XZ, Williams EC, Flegel WA, Klion A. Peripheral blood stem cell transplant-related Plasmodium falciparum infection in a patient with sickle cell disease. Transfusion. 52: 2677-82. PMID 22536941 DOI: 10.1111/J.1537-2995.2012.03673.X  0.363
2012 Babu S, Anuradha R, Kumar NP, George PJ, Kumaraswami V, Nutman TB. Toll-like receptor- and filarial antigen-mediated, mitogen-activated protein kinase- and NF-κB-dependent regulation of angiogenic growth factors in filarial lymphatic pathology. Infection and Immunity. 80: 2509-18. PMID 22508858 DOI: 10.1128/Iai.06179-11  0.313
2012 Dakshinamoorthy G, Samykutty AK, Munirathinam G, Shinde GB, Nutman T, Reddy MV, Kalyanasundaram R. Biochemical characterization and evaluation of a Brugia malayi small heat shock protein as a vaccine against lymphatic filariasis. Plos One. 7: e34077. PMID 22496777 DOI: 10.1371/Journal.Pone.0034077  0.373
2012 Mejia R, Nutman TB. Evaluation and differential diagnosis of marked, persistent eosinophilia. Seminars in Hematology. 49: 149-59. PMID 22449625 DOI: 10.1053/J.Seminhematol.2012.01.006  0.325
2012 Metenou S, Babu S, Nutman TB. Impact of filarial infections on coincident intracellular pathogens: Mycobacterium tuberculosis and Plasmodium falciparum. Current Opinion in Hiv and Aids. 7: 231-8. PMID 22418448 DOI: 10.1097/Coh.0B013E3283522C3D  0.429
2012 Steel C, Varma S, Nutman TB. Regulation of global gene expression in human Loa loa infection is a function of chronicity. Plos Neglected Tropical Diseases. 6: e1527. PMID 22389737 DOI: 10.1371/Journal.Pntd.0001527  0.439
2012 Metenou S, Kovacs M, Dembele B, Coulibaly YI, Klion AD, Nutman TB. Interferon regulatory factor modulation underlies the bystander suppression of malaria antigen-driven IL-12 and IFN-γ in filaria-malaria co-infection. European Journal of Immunology. 42: 641-50. PMID 22213332 DOI: 10.1002/Eji.201141991  0.412
2012 Kumar NP, Hanna LE, Jawahar M, Rekha VB, Sridhar R, Nutman TB, Babu SS. Enhanced frequency of neutrophils and inflammatory monocytes and diminished numbers of T and B cells in active pulmonary tuberculosis Bmc Infectious Diseases. 12. DOI: 10.1186/1471-2334-12-S1-P23  0.384
2011 Kumar NP, Anuradha R, Suresh R, Ganesh R, Shankar J, Kumaraswami V, Nutman TB, Babu S. Suppressed type 1, type 2, and type 17 cytokine responses in active tuberculosis in children. Clinical and Vaccine Immunology : Cvi. 18: 1856-64. PMID 21955625 DOI: 10.1128/Cvi.05366-11  0.349
2011 Fink DL, Kamgno J, Nutman TB. Rapid molecular assays for specific detection and quantitation of Loa loa microfilaremia. Plos Neglected Tropical Diseases. 5: e1299. PMID 21912716 DOI: 10.1371/Journal.Pntd.0001299  0.372
2011 Babu S, Anuradha R, Kumar NP, George PJ, Kumaraswami V, Nutman TB. Filarial lymphatic pathology reflects augmented toll-like receptor-mediated, mitogen-activated protein kinase-mediated proinflammatory cytokine production. Infection and Immunity. 79: 4600-8. PMID 21875961 DOI: 10.1128/Iai.05419-11  0.312
2011 Abraham D, Hess JA, Mejia R, Nolan TJ, Lok JB, Lustigman S, Nutman TB. Immunization with the recombinant antigen Ss-IR induces protective immunity to infection with Strongyloides stercoralis in mice. Vaccine. 29: 8134-40. PMID 21856350 DOI: 10.1016/J.Vaccine.2011.08.030  0.371
2011 Semnani RT, Mahapatra L, Moore V, Sanprasert V, Nutman TB. Functional and phenotypic characteristics of alternative activation induced in human monocytes by interleukin-4 or the parasitic nematode Brugia malayi. Infection and Immunity. 79: 3957-65. PMID 21788379 DOI: 10.1128/Iai.05191-11  0.374
2011 Senbagavalli P, Anuradha R, Ramanathan VD, Kumaraswami V, Nutman TB, Babu S. Heightened measures of immune complex and complement function and immune complex-mediated granulocyte activation in human lymphatic filariasis. The American Journal of Tropical Medicine and Hygiene. 85: 89-96. PMID 21734131 DOI: 10.4269/Ajtmh.2011.11-0086  0.4
2011 Bennuru S, Meng Z, Ribeiro JM, Semnani RT, Ghedin E, Chan K, Lucas DA, Veenstra TD, Nutman TB. Stage-specific proteomic expression patterns of the human filarial parasite Brugia malayi and its endosymbiont Wolbachia. Proceedings of the National Academy of Sciences of the United States of America. 108: 9649-54. PMID 21606368 DOI: 10.1073/Pnas.1011481108  0.309
2011 Ramanathan R, Varma S, Ribeiro JM, Myers TG, Nolan TJ, Abraham D, Lok JB, Nutman TB. Microarray-based analysis of differential gene expression between infective and noninfective larvae of Strongyloides stercoralis. Plos Neglected Tropical Diseases. 5: e1039. PMID 21572524 DOI: 10.1371/Journal.Pntd.0001039  0.316
2011 Steel C, Nutman TB. Altered T cell memory and effector cell development in chronic lymphatic filarial infection that is independent of persistent parasite antigen. Plos One. 6: e19197. PMID 21559422 DOI: 10.1371/Journal.Pone.0019197  0.377
2011 Metenou S, Dembele B, Konate S, Dolo H, Coulibaly YI, Diallo AA, Soumaoro L, Coulibaly ME, Coulibaly SY, Sanogo D, Doumbia SS, Traoré SF, Mahanty S, Klion A, Nutman TB. Filarial infection suppresses malaria-specific multifunctional Th1 and Th17 responses in malaria and filarial coinfections. Journal of Immunology (Baltimore, Md. : 1950). 186: 4725-33. PMID 21411732 DOI: 10.4049/Jimmunol.1003778  0.442
2011 Santiago HC, Bennuru S, Boyd A, Eberhard M, Nutman TB. Structural and immunologic cross-reactivity among filarial and mite tropomyosin: implications for the hygiene hypothesis. The Journal of Allergy and Clinical Immunology. 127: 479-86. PMID 21185070 DOI: 10.1016/J.Jaci.2010.11.007  0.669
2011 Fink DL, Fahle GA, Fischer S, Fedorko DF, Nutman TB. Toward molecular parasitologic diagnosis: Enhanced diagnostic sensitivity for filarial infections in mobile populations Journal of Clinical Microbiology. 49: 42-47. PMID 20980560 DOI: 10.1128/Jcm.01697-10  0.321
2010 Aravindhan V, Mohan V, Surendar J, Rao MM, Ranjani H, Kumaraswami V, Nutman TB, Babu S. Decreased prevalence of lymphatic filariasis among subjects with type-1 diabetes. The American Journal of Tropical Medicine and Hygiene. 83: 1336-9. PMID 21118945 DOI: 10.4269/Ajtmh.2010.10-0410  0.302
2010 Semnani RT, Mahapatra L, Dembele B, Konate S, Metenou S, Dolo H, Coulibaly ME, Soumaoro L, Coulibaly SY, Sanogo D, Seriba Doumbia S, Diallo AA, Traoré SF, Klion A, Nutman TB, et al. Expanded numbers of circulating myeloid dendritic cells in patent human filarial infection reflect lower CCR1 expression. Journal of Immunology (Baltimore, Md. : 1950). 185: 6364-72. PMID 20956349 DOI: 10.4049/Jimmunol.1001605  0.419
2010 Krolewiecki AJ, Ramanathan R, Fink V, McAuliffe I, Cajal SP, Won K, Juarez M, Di Paolo A, Tapia L, Acosta N, Lee R, Lammie P, Abraham D, Nutman TB. Improved diagnosis of Strongyloides stercoralis using recombinant antigen-based serologies in a community-wide study in northern Argentina. Clinical and Vaccine Immunology : Cvi. 17: 1624-30. PMID 20739501 DOI: 10.1128/Cvi.00259-10  0.388
2010 Metenou S, Dembele B, Konate S, Dolo H, Coulibaly SY, Coulibaly YI, Diallo AA, Soumaoro L, Coulibaly ME, Sanogo D, Doumbia SS, Traoré SF, Mahanty S, Klion A, Nutman TB. At homeostasis filarial infections have expanded adaptive T regulatory but not classical Th2 cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 5375-82. PMID 20357251 DOI: 10.4049/Jimmunol.0904067  0.393
2010 Babu S, Bhat SQ, Pavan Kumar N, Kumaraswami V, Nutman TB. Regulatory T cells modulate Th17 responses in patients with positive tuberculin skin test results Journal of Infectious Diseases. 201: 20-31. PMID 19929695 DOI: 10.1086/648735  0.373
2010 Ramanathan R, Nutman T. Strongyloides stercoralis infection in the immunocompromised host. Current Infectious Disease Reports. 10: 105-10. PMID 18462583 DOI: 10.1007/s11908-008-0019-6  0.318
2010 Santiago H, Bennuru S, Nutman T. Hygiene Hypothesis Revisited: Marked Cross-reactivity Among Allergen- And Parasitic Helminth-specific B Cell Epitopes Journal of Allergy and Clinical Immunology. 125: AB127. DOI: 10.1016/J.Jaci.2009.12.499  0.319
2009 Bennuru S, Nutman TB. Lymphatics in human lymphatic filariasis: in vitro models of parasite-induced lymphatic remodeling Lymphatic Research and Biology. 7: 215-219. PMID 20143920 DOI: 10.1089/Lrb.2009.0022  0.308
2009 Bennuru S, Nutman TB. Lymphangiogenesis and lymphatic remodeling induced by filarial parasites: Implications for pathogenesis Plos Pathogens. 5. PMID 20011114 DOI: 10.1371/Journal.Ppat.1000688  0.436
2009 Coulibaly YI, Dembele B, Diallo AA, Lipner EM, Doumbia SS, Coulibaly SY, Konate S, Diallo DA, Yalcouye D, Kubofcik J, Doumbo OK, Traore AK, Keita AD, Fay MP, Traore SF, ... Nutman TB, et al. A randomized trial of doxycycline for Mansonella perstans infection. The New England Journal of Medicine. 361: 1448-58. PMID 19812401 DOI: 10.1056/Nejmoa0900863  0.316
2009 Cuenco KT, Ottesen EA, Williams SA, Nutman TB, Steel C. Heritable factors play a major role in determining host responses to Wuchereria bancrofti infection in an isolated South Pacific island population. The Journal of Infectious Diseases. 200: 1271-8. PMID 19754310 DOI: 10.1086/605844  0.345
2009 Babu S, Bhat SQ, Kumar NP, Anuradha R, Kumaran P, Gopi PG, Kolappan C, Kumaraswami V, Nutman TB. Attenuation of toll-like receptor expression and function in latent tuberculosis by coexistent filarial infection with restoration following antifilarial chemotherapy Plos Neglected Tropical Diseases. 3. PMID 19636364 DOI: 10.1371/Journal.Pntd.0000489  0.405
2009 Metenou S, Dembélé B, Konate S, Dolo H, Coulibaly SY, Coulibaly YI, Diallo AA, Soumaoro L, Coulibaly ME, Sanogo D, Doumbia SS, Wagner M, Traoré SF, Klion A, Mahanty S, ... Nutman TB, et al. Patent filarial infection modulates malaria-specific type 1 cytokine responses in an IL-10-dependent manner in a filaria/malaria-coinfected population. Journal of Immunology (Baltimore, Md. : 1950). 183: 916-24. PMID 19561105 DOI: 10.4049/Jimmunol.0900257  0.416
2009 Babu S, Bhat SQ, Pavan Kumar N, Jayantasri S, Rukmani S, Kumaran P, Gopi PG, Kolappan C, Kumaraswami V, Nutman TB. Human type 1 and 17 responses in latent tuberculosis are modulated by coincident filarial infection through cytotoxic T lymphocyte antigen-4 and programmed death-1 Journal of Infectious Diseases. 200: 288-298. PMID 19505258 DOI: 10.1086/599797  0.428
2009 Babu S, Kumaraswami V, Nutman TB. Alternatively activated and immunoregulatory monocytes in human filarial infections Journal of Infectious Diseases. 199: 1827-1837. PMID 19456233 DOI: 10.1086/599090  0.435
2009 Burbelo PD, Leahy HP, Iadarola MJ, Nutman TB. A four-antigen mixture for rapid assessment of Onchocerca volvulus infection. Plos Neglected Tropical Diseases. 3: e438. PMID 19436728 DOI: 10.1371/Journal.Pntd.0000438  0.437
2009 Guadalupe I, Mitre E, Benitez S, Chico ME, Nutman TB, Cooper PJ. Evidence for in utero sensitization to Ascaris lumbricoides in newborns of mothers with ascariasis. The Journal of Infectious Diseases. 199: 1846-50. PMID 19426111 DOI: 10.1086/599214  0.443
2009 Babu S, Bhat SQ, Kumar NP, Lipira AB, Kumar S, Karthik C, Kumaraswami V, Nutman TB. Filarial lymphedema is characterized by antigen-specific Th1 and Th17 proinflammatory responses and a lack of regulatory T cells Plos Neglected Tropical Diseases. 3. PMID 19381284 DOI: 10.1371/Journal.Pntd.0000420  0.415
2009 Venugopal PG, Nutman TB, Semnani RT. Activation and regulation of Toll-Like Receptors (TLRs) by helminth parasites Immunologic Research. 43: 252-263. PMID 18982454 DOI: 10.1007/S12026-008-8079-0  0.422
2009 Brodine SK, Nou J, Burbelo P, Reed SL, Wilkins P, Nutman T, Leake J, Wolf J, Huang R, Moser K, Thomas A, Mehta S, Harbertson J, Ramanathan R. Community Based Parasitic Screening and Treatment of Sudanese Refugees: Application and Assessment of Centers for Disease Control Guidelines The American Journal of Tropical Medicine and Hygiene. 80: 425-430. DOI: 10.4269/Ajtmh.2009.80.425  0.317
2008 Semnani RT, Venugopal PG, Mahapatra L, Skinner JA, Meylan F, Chien D, Dorward DW, Chaussabel D, Siegel RM, Nutman TB. Induction of TRAIL- and TNF-alpha-dependent apoptosis in human monocyte-derived dendritic cells by microfilariae of Brugia malayi. Journal of Immunology (Baltimore, Md. : 1950). 181: 7081-9. PMID 18981128 DOI: 10.4049/Jimmunol.181.10.7081  0.304
2008 Talaat KR, Kumarasamy N, Swaminathan S, Gopinath R, Nutman TB. Filarial/human immunodeficiency virus coinfection in urban southern India American Journal of Tropical Medicine and Hygiene. 79: 558-560. PMID 18840744 DOI: 10.4269/Ajtmh.2008.79.558  0.32
2008 Ramanathan R, Burbelo PD, Groot S, Iadarola MJ, Neva FA, Nutman TB. A luciferase immunoprecipitation systems assay enhances the sensitivity and specificity of diagnosis of Strongyloides stercoralis infection. The Journal of Infectious Diseases. 198: 444-51. PMID 18558872 DOI: 10.1086/589718  0.397
2008 Semnani RT, Venugopal PG, Leifer CA, Mostböck S, Sabzevari H, Nutman TB. Inhibition of TLR3 and TLR4 function and expression in human dendritic cells by helminth parasites. Blood. 112: 1290-8. PMID 18541719 DOI: 10.1182/Blood-2008-04-149856  0.345
2008 Keiser PB, Coulibaly Y, Kubofcik J, Diallo AA, Klion AD, Traoré SF, Nutman TB. Molecular identification of Wolbachia from the filarial nematode Mansonella perstans Molecular and Biochemical Parasitology. 160: 123-128. PMID 18538871 DOI: 10.1016/J.Molbiopara.2008.04.012  0.328
2008 Chang LW, Reller ME, Bishop JA, Talaat K, Nutman TB, Auwaerter PG. A 41-year-old woman from Cameroon with infertility. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 47: 141-3, 109. PMID 18522508 DOI: 10.1086/588787  0.331
2008 Burbelo PD, Ramanathan R, Klion AD, Iadarola MJ, Nutman TB. Rapid, novel, specific, high-throughput assay for diagnosis of Loa loa infection. Journal of Clinical Microbiology. 46: 2298-304. PMID 18508942 DOI: 10.1128/Jcm.00490-08  0.402
2008 Cooper PJ, Mitre E, Moncayo AL, Chico ME, Vaca MG, Nutman TB. Ascaris lumbricoides-induced interleukin-10 is not associated with atopy in schoolchildren in a rural area of the tropics Journal of Infectious Diseases. 197: 1333-1340. PMID 18422446 DOI: 10.1086/586904  0.419
2008 Frances SP, Baade LM, Kubofcik J, Nutman TB, Melrose WD, McCarthy JS, Nissen MD. Seroconversion to filarial antigens in Australian defence force personnel in Timor-Leste American Journal of Tropical Medicine and Hygiene. 78: 560-563. PMID 18385349 DOI: 10.4269/Ajtmh.2008.78.560  0.329
2008 Mitre E, Chien D, Nutman TB. CD4+ (and not CD25+) T cells are the predominant interleukin-10-producing cells in the circulation of filaria-infected patients Journal of Infectious Diseases. 197: 94-101. PMID 18171291 DOI: 10.1086/524301  0.381
2008 Ramanathan R, Nutman TB. Strongyloides stercoralis infection in the immunocompromised host Current Infectious Disease Reports. 10: 105-110. DOI: 10.1007/S11908-008-0019-6  0.427
2007 Babu S, Blauvelt CP, Nutman TB. Filarial parasites induce NK cell activation, type 1 and type 2 cytokine secretion, and subsequent apoptotic cell death Journal of Immunology. 179: 2445-2456. PMID 17675506 DOI: 10.4049/Jimmunol.179.4.2445  0.403
2007 Kim YJ, Dale JK, Noel P, Brown MR, Nutman TB, Straus SE, Klion AD. Eosinophilia is associated with a higher mortality rate among patients with autoimmune lymphoproliferative syndrome. American Journal of Hematology. 82: 615-24. PMID 17266055 DOI: 10.1002/Ajh.20851  0.324
2006 Cheng YX, Foster B, Holland SM, Klion AD, Nutman TB, Casale TB, Metcalfe DD, Prussin C. CD2 identifies a monocyte subpopulation with immunoglobulin E-dependent, high-level expression of FcεRI Clinical and Experimental Allergy. 36: 1436-1445. PMID 17083354 DOI: 10.1111/J.1365-2222.2006.02578.X  0.304
2006 Semnani RT, Keiser PB, Coulibaly YI, Keita F, Diallo AA, Traore D, Diallo DA, Doumbo OK, Traore SF, Kubofcik J, Klion AD, Nutman TB. Filaria-induced monocyte dysfunction and its reversal following treatment Infection and Immunity. 74: 4409-4417. PMID 16861626 DOI: 10.1128/Iai.01106-05  0.409
2006 Lipner EM, Gopi PG, Subramani R, Kolappan C, Sadacharam K, Kumaran P, Prevots DR, Narayanan PR, Nutman TB, Kumaraswami V. Coincident filarial, intestinal helminth, and mycobacterial infection: helminths fail to influence tuberculin reactivity, but BCG influences hookworm prevalence. The American Journal of Tropical Medicine and Hygiene. 74: 841-7. PMID 16687690 DOI: 10.4269/Ajtmh.2006.74.841  0.393
2006 McPherson T, Persaud S, Singh S, Fay MP, Addiss D, Nutman TB, Hay R. Interdigital lesions and frequency of acute dermatolymphangioadenitis in lymphoedema in a filariasis-endemic area British Journal of Dermatology. 154: 933-941. PMID 16634898 DOI: 10.1111/J.1365-2133.2005.07081.X  0.303
2006 Mitre E, Nutman TB. IgE memory: Persistence of antigen-specific IgE responses years after treatment of human filarial infections Journal of Allergy and Clinical Immunology. 117: 939-945. PMID 16630955 DOI: 10.1016/J.Jaci.2005.12.1341  0.464
2006 Babu S, Blauvelt CP, Kumaraswami V, Nutman TB. Cutting edge: Diminished T cell TLR expression and function modulates the immune response in human filarial infection Journal of Immunology. 176: 3885-3889. PMID 16547219 DOI: 10.4049/Jimmunol.176.7.3885  0.334
2006 Babu S, Blauvelt CP, Kumaraswami V, Nutman TB. Regulatory networks induced by live parasites impair both Th1 and Th2 pathways in patent lymphatic filariasis: Implications for parasite persistence Journal of Immunology. 176: 3248-3256. PMID 16493086 DOI: 10.4049/Jimmunol.176.5.3248  0.416
2006 Nutman TB. Asymptomatic peripheral blood eosinophilia redux: Common parasitic infections presenting frequently in refugees and immigrants Clinical Infectious Diseases. 42: 368-369. PMID 16392082 DOI: 10.1086/499247  0.384
2006 Talaat KR, Bonawitz RE, Domenech P, Nutman TB. Preexposure to live Brugia malayi microfilariae alters the innate response of human dendritic cells to Mycobacterium tuberculosis Journal of Infectious Diseases. 193: 196-204. PMID 16362883 DOI: 10.1086/498912  0.375
2006 Mitre E, Nutman TB. Basophils, basophilia and helminth infections Chemical Immunology and Allergy. 90: 141-156. PMID 16210908 DOI: 10.1159/000088886  0.441
2006 Kim YJ, Nutman TB. Eosinophilia: Causes and pathobiology in persons with prior exposures in tropical areas with an emphasis on parasitic infections Current Infectious Disease Reports. 8: 43-50. DOI: 10.1007/S11908-006-0034-4  0.379
2005 Babu S, Blauvelt CP, Kumaraswami V, Nutman TB. Diminished expression and function of TLR in lymphatic filariasis: A novel mechanism of immune dysregulation Journal of Immunology. 175: 1170-1176. PMID 16002719 DOI: 10.4049/Jimmunol.175.2.1170  0.372
2005 Mitre E, Norwood S, Nutman TB. Saturation of immunoglobulin E (IgE) binding sites by polyclonal IgE does not explain the protective effect of helminth infections against atopy Infection and Immunity. 73: 4106-4111. PMID 15972499 DOI: 10.1128/Iai.73.7.4106-4111.2005  0.409
2005 Babu S, Kumaraswami V, Nutman TB. Transcriptional control of impaired Th1 responses in patent lymphatic filariasis by T-box expressed in T cells and suppressor of cytokine signaling genes Infection and Immunity. 73: 3394-3401. PMID 15908366 DOI: 10.1128/Iai.73.6.3394-3401.2005  0.381
2005 Sasisekhar B, Aparna M, Augustin DJ, Kaliraj P, Kar SK, Nutman TB, Narayanan RB. Diminished monocyte function in microfilaremic patients with lymphatic filariasis and its relationship to altered lymphoproliferative responses. Infection and Immunity. 73: 3385-93. PMID 15908365 DOI: 10.1128/Iai.73.6.3385-3393.2005  0.45
2005 Ravi V, King TP, Andersen JF, Nutman TB, Neva FA. Strongyloides stercoralis recombinant NIE antigen shares epitope with recombinant Ves v 5 and Pol a 5 allergens of insects American Journal of Tropical Medicine and Hygiene. 72: 549-553. PMID 15891128 DOI: 10.4269/Ajtmh.2005.72.549  0.328
2005 Gallego SG, Loukas A, Slade RW, Neva FA, Varatharajalu R, Nutman TB, Brindley PJ. Identification of an astacin-like metallo-proteinase transcript from the infective larvae of Strongyloides stercoralis Parasitology International. 54: 123-133. PMID 15866474 DOI: 10.1016/J.Parint.2005.02.002  0.317
2005 Kerepesi LA, Keiser PB, Nolan TJ, Schad GA, Abraham D, Nutman TB. DNA immunization with Na+-K+ ATPase (Sseat-6) induces protective immunity to larval Strongyloides stercoralis in mice. Infection and Immunity. 73: 2298-305. PMID 15784574 DOI: 10.1128/Iai.73.4.2298-2305.2005  0.33
2005 Babu S, Blauvelt CP, Kumaraswami V, Nutman TB. Chemokine receptors of T cells and of B cells in lymphatic filarial infection: A role for CCR9 in pathogenesis Journal of Infectious Diseases. 191: 1018-1026. PMID 15717282 DOI: 10.1086/427658  0.354
2004 Ramachandran S, Kumar MP, Rami RMV, Chinnaiah HB, Nutman T, Kaliraj P, McCarthy J. The larval specific lymphatic filarial ALT-2: induction of protection using protein or DNA vaccination. Microbiology and Immunology. 48: 945-955. PMID 15611611 DOI: 10.1111/J.1348-0421.2004.Tb03624.X  0.335
2004 Diaz LA, Arteaga LA, Hilario-Vargas J, Valenzuela JG, Li N, Warren S, Aoki V, Hans-Filho G, Eaton D, dos Santos V, Nutman TB, de Mayolo AA, Qaqish BF, Sampaio SA, Rivitti EA, et al. Anti-desmoglein-1 antibodies in onchocerciasis, leishmaniasis and Chagas disease suggest a possible etiological link to Fogo selvagem. The Journal of Investigative Dermatology. 123: 1045-51. PMID 15610512 DOI: 10.1111/J.0022-202X.2004.23438.X  0.327
2004 Kim YJ, Prussin C, Martin B, Law MA, Haverty TP, Nutman TB, Klion AD. Rebound eosinophilia after treatment of hypereosinophilic syndrome and eosinophilic gastroenteritis with monoclonal anti-IL-5 antibody SCH55700. The Journal of Allergy and Clinical Immunology. 114: 1449-55. PMID 15577851 DOI: 10.1016/J.Jaci.2004.08.027  0.319
2004 Semnani RT, Nutman TB. Toward an understanding of the interaction between filarial parasites and host antigen-presenting cells Immunological Reviews. 201: 127-138. PMID 15361237 DOI: 10.1111/J.0105-2896.2004.00196.X  0.4
2004 Cooper PJ, Chico ME, Sandoval C, Nutman TB. Atopic phenotype is an important determinant of immunoglobulin E-mediated inflammation and expression of T helper cell type 2 cytokines to Ascaris antigens in children exposed to ascariasis Journal of Infectious Diseases. 190: 1338-1346. PMID 15346347 DOI: 10.1086/423944  0.414
2004 Gnanasekar M, Rao KVN, He YX, Mishra PK, Nutman TB, Kaliraj P, Ramaswamy K. Novel phage display-based subtractive screening to identify vaccine candidates of Brugia malayi Infection and Immunity. 72: 4707-4715. PMID 15271932 DOI: 10.1128/Iai.72.8.4707-4715.2004  0.36
2004 Semnani RT, Law M, Kubofcik J, Nutman TB. Filaria-Induced Immune Evasion: Suppression by the Infective Stage of Brugia malayi at the Earliest Host-Parasite Interface Journal of Immunology. 172: 6229-6238. PMID 15128811 DOI: 10.4049/Jimmunol.172.10.6229  0.416
2004 Nookala S, Srinivasan S, Kaliraj P, Narayanan RB, Nutman TB. Impairment of tetanus-specific cellular and humoral responses following tetanus vaccination in human lymphatic filariasis. Infection and Immunity. 72: 2598-604. PMID 15102768 DOI: 10.1128/Iai.72.5.2598-2604.2004  0.381
2004 Kerepesi LA, Nolan TJ, Schad GA, Lustigman S, Herbert DR, Keiser PB, Nutman TB, Krolewiecki AJ, Abraham D. Human immunoglobulin G mediates protective immunity and identifies protective antigens against larval Strongyloides stercoralis in mice. The Journal of Infectious Diseases. 189: 1282-90. PMID 15031798 DOI: 10.1086/382484  0.331
2004 Ravi V, Kubofcik J, Bandopathyaya S, Geetha M, Narayanan RB, Nutman TB, Kaliraj P. Wuchereria bancrofti: cloning and characterization of heat shock protein 70 from the human lymphatic filarial parasite. Experimental Parasitology. 106: 1-10. PMID 15013783 DOI: 10.1016/J.Exppara.2004.01.001  0.34
2004 Mitre E, Taylor RT, Kubofcik J, Nutman TB. Parasite Antigen-Driven Basophils Are a Major Source of IL-4 in Human Filarial Infections Journal of Immunology. 172: 2439-2445. PMID 14764715 DOI: 10.4049/Jimmunol.172.4.2439  0.383
2004 Keiser PB, Nutman TB. Strongyloides stercoralis in the Immunocompromised Population. Clinical Microbiology Reviews. 17: 208-17. PMID 14726461 DOI: 10.1128/Cmr.17.1.208-217.2004  0.392
2004 Klion AD, Nutman TB. The role of eosinophils in host defense against helminth parasites The Journal of Allergy and Clinical Immunology. 113: 30-37. PMID 14713904 DOI: 10.1016/J.Jaci.2003.10.050  0.411
2003 Klion AD, Law MA, Noel P, Kim YJ, Haverty TP, Nutman TB. Safety and efficacy of the monoclonal anti-interleukin-5 antibody SCH55700 in the treatment of patients with hypereosinophilic syndrome. Blood. 103: 2939-41. PMID 15070668 DOI: 10.1182/Blood-2003-10-3620  0.32
2003 Babu S, Nutman TB. Proinflammatory Cytokines Dominate the Early Immune Response to Filarial Parasites Journal of Immunology. 171: 6723-6732. PMID 14662876 DOI: 10.4049/Jimmunol.171.12.6723  0.419
2003 Rahmah N, Shenoy RK, Nutman TB, Weiss N, Gilmour K, Maizels RM, Yazdanbakhsh M, Sartono E. Multicentre laboratory evaluation of Brugia Rapid dipstick test for detection of brugian filariasis. Tropical Medicine & International Health : Tm & Ih. 8: 895-900. PMID 14516300 DOI: 10.1046/J.1365-3156.2003.01102.X  0.329
2003 Mitre E, Nutman TB. Lack of basophilia in human parasitic infections. The American Journal of Tropical Medicine and Hygiene. 69: 87-91. PMID 12932104  0.312
2003 Semnani RT, Liu AY, Sabzevari H, Kubofcik J, Zhou J, Gilden JK, Nutman TB. Brugia malayi microfilariae induce cell death in human dendritic cells, inhibit their ability to make IL-12 and IL-10, and reduce their capacity to activate CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 1950-60. PMID 12902498 DOI: 10.4049/Jimmunol.171.4.1950  0.39
2003 Mitre E, Thompson RW, Carvalho EM, Nutman TB, Neva FA. Majority of interferon-gamma-producing CD4+ cells in patients infected with human T cell lymphotrophic virus do not express tax protein. The Journal of Infectious Diseases. 188: 428-32. PMID 12870125 DOI: 10.1086/376529  0.364
2003 Garraud O, Perraut R, Riveau G, Nutman TB. Class and subclass selection in parasite-specific antibody responses. Trends in Parasitology. 19: 300-4. PMID 12855380 DOI: 10.1016/S1471-4922(03)00139-9  0.389
2003 Choi EH, Nutman TB, Chanock SJ. Genetic variation in immune function and susceptibility to human filariasis. Expert Review of Molecular Diagnostics. 3: 367-74. PMID 12779010 DOI: 10.1586/14737159.3.3.367  0.392
2003 Cooper PJ, Chico ME, Rodrigues LC, Ordonez M, Strachan D, Griffin GE, Nutman TB. Reduced risk of atopy among school-age children infected with geohelminth parasites in a rural area of the tropics Journal of Allergy and Clinical Immunology. 111: 995-1000. PMID 12743563 DOI: 10.1067/Mai.2003.1348  0.394
2003 Cooper PJ, Chico ME, Bland M, Griffin GE, Nutman TB. Allergic symptoms, atopy, and geohelminth infections in a rural area of Ecuador American Journal of Respiratory and Critical Care Medicine. 168: 313-317. PMID 12714349 DOI: 10.1164/Rccm.200211-1320Oc  0.336
2003 Wu Y, Egerton G, McCarthy JS, Nutman TB, Bianco AE. Human immune responses to infective stage larval-specific chitinase of filarial parasite, Onchocerca volvulus, Ov-CHI-1. Filaria Journal. 2: 6. PMID 12685941 DOI: 10.1186/1475-2883-2-6  0.364
2003 Chaussabel D, Semnani RT, McDowell MA, Sacks D, Sher A, Nutman TB. Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites. Blood. 102: 672-81. PMID 12663451 DOI: 10.1182/Blood-2002-10-3232  0.347
2003 O'Bryan L, Pinkston P, Kumaraswami V, Vijayan V, Yenokida G, Rosenberg HF, Crystal R, Ottesen EA, Nutman TB. Localized eosinophil degranulation mediates disease in tropical pulmonary eosinophilia. Infection and Immunity. 71: 1337-42. PMID 12595450 DOI: 10.1128/Iai.71.3.1337-1342.2003  0.334
2003 Steel C, Nutman TB. CTLA-4 in filarial infections: implications for a role in diminished T cell reactivity. Journal of Immunology (Baltimore, Md. : 1950). 170: 1930-8. PMID 12574361 DOI: 10.4049/Jimmunol.170.4.1930  0.444
2003 Lobos E, Nutman TB, Hothersall JS, Moncada S. Elevated immunoglobulin E against recombinant Brugia malayi gamma-glutamyl transpeptidase in patients with bancroftian filariasis: association with tropical pulmonary eosinophilia or putative immunity. Infection and Immunity. 71: 747-53. PMID 12540554 DOI: 10.1128/Iai.71.2.747-753.2003  0.36
2003 Lalitha P, Eswaran D, Gnanasekar M, Rao KV, Narayanan RB, Scott A, Nutman T, Kaliraj P, Gnanasekar M. Development of antigen detection ELISA for the diagnosis of brugian and bancroftian filariasis using antibodies to recombinant filarial antigens Bm-SXP-1 and Wb-SXP-1. Microbiology and Immunology. 46: 327-32. PMID 12139392 DOI: 10.1111/j.1348-0421.2002.tb02703.x  0.306
2003 Mitre E, Nutman TB. Lack of basophilia in human parasitic infections. American Journal of Tropical Medicine and Hygiene. 69: 87-91. DOI: 10.4269/Ajtmh.2003.69.87  0.425
2003 KEISER PB, TRAORE D, COULIBALY YI, KEITA F, NUTMAN TB, DIALLO DA, KLION AD, DIALLO A, DOUMBO OK, SEMNANI RT, TRAORE SF. CLINICAL CHARACTERISTICS OF POST-TREATMENT REACTIONS TO IVERMECTIN/ALBENDAZOLE FOR WUCHERERIA BANCROFTI IN A REGION CO-ENDEMIC FOR MANSONELLA PERSTANS The American Journal of Tropical Medicine and Hygiene. 69: 331-335. DOI: 10.4269/Ajtmh.2003.69.331  0.335
2003 Wu Y, Egerton G, McCarthy JS, Nutman TB, Bianco AE. Human immune responses to infective stage larval-specific chitinase of filarial parasite, Onchocerca volvulus, Ov-CHI-1 Filaria Journal. 2. DOI: 10.1186/1475-2883-2-6  0.465
2002 Klion AD, Vijaykumar A, Oei T, Martin B, Nutman TB. Serum immunoglobulin G4 antibodies to the recombinant antigen, Ll-SXP-1, are highly specific for Loa loa infection. The Journal of Infectious Diseases. 187: 128-33. PMID 12508156 DOI: 10.1086/345873  0.409
2002 Cooper PJ, Schwartz LB, Irani AM, Awadzi K, Guderian RH, Nutman TB. Association of transient dermal mastocytosis and elevated plasma tryptase levels with development of adverse reactions after treatment of onchocerciasis with ivermectin. The Journal of Infectious Diseases. 186: 1307-13. PMID 12402200 DOI: 10.1086/344318  0.303
2002 Nutman TB. Future directions for vaccine-related onchocerciasis research. Trends in Parasitology. 18: 237-9. PMID 12036727 DOI: 10.1016/S1471-4922(02)02310-3  0.365
2002 Garraud O, Perraut R, Diouf A, Nambei WS, Tall A, Spiegel A, Longacre S, Kaslow DC, Jouin H, Mattei D, Engler GM, Nutman TB, Riley EM, Mercereau-Puijalon O. Regulation of antigen-specific immunoglobulin G subclasses in response to conserved and polymorphic Plasmodium falciparum antigens in an in vitro model. Infection and Immunity. 70: 2820-7. PMID 12010968 DOI: 10.1128/Iai.70.6.2820-2827.2002  0.37
2002 Nutman TB. Lymphatic filariasis: new insights and prospects for control. Current Opinion in Infectious Diseases. 14: 539-46. PMID 11964873 DOI: 10.1097/00001432-200110000-00006  0.342
2002 McCarthy JS, Wieseman M, Tropea J, Kaslow D, Abraham D, Lustigman S, Tuan R, Guderian RH, Nutman TB. Onchocerca volvulus glycolytic enzyme fructose-1,6-bisphosphate aldolase as a target for a protective immune response in humans. Infection and Immunity. 70: 851-8. PMID 11796620 DOI: 10.1128/Iai.70.2.851-858.2002  0.366
2001 Klinman DM, Nutman TB. ELISPOT assay to detect cytokine-secreting murine and human cells. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 6.19. PMID 18432809 DOI: 10.1002/0471142735.Im0619S10  0.328
2001 Steel C, Ottesen EA, Weller PF, Nutman TB. Worm burden and host responsiveness in Wuchereria bancrofti infection: use of antigen detection to refine earlier assessments from the South Pacific. The American Journal of Tropical Medicine and Hygiene. 65: 498-503. PMID 11716104 DOI: 10.4269/Ajtmh.2001.65.498  0.393
2001 Marovich MA, Lira R, Shepard M, Fuchs GH, Kruetzer R, Nutman TB, Neva FA. Leishmaniasis recidivans recurrence after 43 years: a clinical and immunologic report after successful treatment. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 33: 1076-9. PMID 11528583 DOI: 10.1086/322643  0.303
2001 Choi EH, Zimmerman PA, Foster CB, Zhu S, Kumaraswami V, Nutman TB, Chanock SJ. Genetic polymorphisms in molecules of innate immunity and susceptibility to infection with Wuchereria bancrofti in South India Genes and Immunity. 2: 248-253. PMID 11528516 DOI: 10.1038/Sj.Gene.6363767  0.341
2001 Semnani RT, Sabzevari H, Iyer R, Nutman TB. Filarial antigens impair the function of human dendritic cells during differentiation. Infection and Immunity. 69: 5813-22. PMID 11500459 DOI: 10.1128/Iai.69.9.5813-5822.2001  0.38
2001 Nutman TB, Kumaraswami V. Regulation of the immune response in lymphatic filariasis: perspectives on acute and chronic infection with Wuchereria bancrofti in South India. Parasite Immunology. 23: 389-99. PMID 11472558 DOI: 10.1046/J.1365-3024.2001.00399.X  0.443
2001 Cooper PJ, Mancero T, Espinel M, Sandoval C, Lovato R, Guderian RH, Nutman TB. Early human infection with Onchocerca volvulus is associated with an enhanced parasite-specific cellular immune response. The Journal of Infectious Diseases. 183: 1662-8. PMID 11343216 DOI: 10.1086/320709  0.469
2001 Cooper PJ, Chico M, Sandoval C, Espinel I, Guevara A, Levine MM, Griffin GE, Nutman TB. Human infection with Ascaris lumbricoides is associated with suppression of the interleukin-2 response to recombinant cholera toxin B subunit following vaccination with the live oral cholera vaccine CVD 103-HgR Infection and Immunity. 69: 1574-1580. PMID 11179329 DOI: 10.1128/Iai.69.3.1574-1580.2001  0.36
2000 Henry NL, Law M, Nutman TB, Klion AD. Onchocerciasis in a nonendemic population: clinical and immunologic assessment before treatment and at the time of presumed cure. The Journal of Infectious Diseases. 183: 512-6. PMID 11133386 DOI: 10.1086/318088  0.433
2000 Gopinath R, Ostrowski M, Justement SJ, Fauci AS, Nutman TB. Filarial infections increase susceptibility to human immunodeficiency virus infection in peripheral blood mononuclear cells in vitro. The Journal of Infectious Diseases. 182: 1804-8. PMID 11069260 DOI: 10.1086/317623  0.405
2000 Weil GJ, Steel C, Liftis F, Li BW, Mearns G, Lobos E, Nutman TB. A rapid-format antibody card test for diagnosis of onchocerciasis. The Journal of Infectious Diseases. 182: 1796-9. PMID 11069258 DOI: 10.1086/317629  0.306
2000 Cooper PJ, Chico ME, Sandoval C, Espinel I, Guevara A, Kennedy MW, Urban J.F. J, Griffin GE, Nutman TB. Human infection with Ascaris lumbricoides is associated with a polarized cytokine response Journal of Infectious Diseases. 182: 1207-1213. PMID 10979919 DOI: 10.1086/315830  0.449
2000 Cooper PJ, Chico ME, Losonsky G, Sandoval C, Espinel I, Sridhara R, Aguilar M, Guevara A, Guderian RH, Levine MM, Griffin GE, Nutman TB. Albendazole treatment of children with ascariasis enhances the vibriocidal antibody response to the live attenuated oral cholera vaccine CVD 103-HgR Journal of Infectious Diseases. 182: 1199-1206. PMID 10979918 DOI: 10.1086/315837  0.343
2000 Marovich MA, McDowell MA, Thomas EK, Nutman TB. IL-12p70 production by Leishmania major-harboring human dendritic cells is a CD40/CD40 ligand-dependent process. Journal of Immunology (Baltimore, Md. : 1950). 164: 5858-65. PMID 10820265 DOI: 10.4049/Jimmunol.164.11.5858  0.425
2000 Cooper PJ, Beck LA, Espinel I, Deyampert NM, Hartnell A, Jose PJ, Paredes W, Guderian RH, Nutman TB. Eotaxin and RANTES expression by the dermal endothelium is associated with eosinophil infiltration after ivermectin treatment of onchocerciasis. Clinical Immunology (Orlando, Fla.). 95: 51-61. PMID 10794432 DOI: 10.1006/Clim.1999.4829  0.313
2000 Gopinath R, Hanna LE, Kumaraswami V, Perumal V, Kavitha V, Vijayasekaran V, Nutman TB. Perturbations in eosinophil homeostasis following treatment of lymphatic filariasis. Infection and Immunity. 68: 93-9. PMID 10603373 DOI: 10.1128/Iai.68.1.93-99.2000  0.378
1999 Stewart GR, Boussinesq M, Coulson T, Elson L, Nutman T, Bradley JE. Onchocerciasis modulates the immune response to mycobacterial antigens. Clinical and Experimental Immunology. 117: 517-23. PMID 10469056 DOI: 10.1046/J.1365-2249.1999.01015.X  0.428
1999 Gopinath R, Hanna LE, Kumaraswami V, Pillai SV, Kavitha V, Vijayasekaran V, Rajasekharan A, Nutman TB. Long-term persistence of cellular hyporesponsiveness to filarial antigens after clearance of microfilaremia. The American Journal of Tropical Medicine and Hygiene. 60: 848-53. PMID 10344663 DOI: 10.4269/Ajtmh.1999.60.848  0.367
1999 Cooper PJ, Awadzi K, Ottesen EA, Remick D, Nutman TB. Eosinophil sequestration and activation are associated with the onset and severity of systemic adverse reactions following the treatment of onchocerciasis with ivermectin. The Journal of Infectious Diseases. 179: 738-42. PMID 9952390 DOI: 10.1086/314647  0.356
1999 Garraud O, Mollis SN, Holland SM, Sneller MC, Malech HL, Gallin JI, Nutman TB. Regulation of immunoglobulin production in hyper-IgE (Job's) syndrome. The Journal of Allergy and Clinical Immunology. 103: 333-40. PMID 9949327 DOI: 10.1016/S0091-6749(99)70510-5  0.345
1999 Bloch P, Simonsen PE, Weiss N, Nutman TB. The significance of guinea worm infection in the immunological diagnosis of onchocerciasis and bancroftian filariasis. Transactions of the Royal Society of Tropical Medicine and Hygiene. 92: 518-21. PMID 9861367 DOI: 10.1016/S0035-9203(98)90899-9  0.397
1999 Cooper PJ, Espinel I, Wieseman M, Paredes W, Espinel M, Guderian RH, Nutman TB. Human Onchocerciasis and Tetanus Vaccination: Impact on the Postvaccination Antitetanus Antibody Response Infection and Immunity. 67: 5951-5957. DOI: 10.1128/Iai.67.11.5951-5957.1999  0.414
1998 Karp CL, Wysocka M, Ma X, Marovich M, Factor RE, Nutman T, Armant M, Wahl L, Cuomo P, Trinchieri G. Potent suppression of IL-12 production from monocytes and dendritic cells during endotoxin tolerance. European Journal of Immunology. 28: 3128-36. PMID 9808181 DOI: 10.1002/(Sici)1521-4141(199810)28:10<3128::Aid-Immu3128>3.0.Co;2-T  0.358
1998 Cooper PJ, Espinel I, Paredes W, Guderian RH, Nutman TB. Impaired tetanus-specific cellular and humoral responses following tetanus vaccination in human onchocerciasis: a possible role for interleukin-10. The Journal of Infectious Diseases. 178: 1133-8. PMID 9806045 DOI: 10.1086/515661  0.407
1998 Moore TA, Nutman TB. Eosinophilia in the returning traveler. Infectious Disease Clinics of North America. 12: 503-21. PMID 9658256 DOI: 10.1016/S0891-5520(05)70016-7  0.36
1998 Lin AY, Nutman TB, Kaslow D, Mulvihill JJ, Fontaine L, White BJ, Knutsen T, Theil KS, Raghuprasad PK, Goldstein AM, Tucker MA. Familial eosinophilia: clinical and laboratory results on a U.S. kindred. American Journal of Medical Genetics. 76: 229-37. PMID 9508242 DOI: 10.1002/(Sici)1096-8628(19980319)76:3<229::Aid-Ajmg6>3.0.Co;2-L  0.386
1997 Cooper PJ, Guderian RH, Nutman TB, Taylor DW. Human infection with Onchocerca volvulus does not affect the T helper cell phenotype of the cellular immune response to mycobacterial antigen. Transactions of the Royal Society of Tropical Medicine and Hygiene. 91: 350-2. PMID 9231215 DOI: 10.1016/S0035-9203(97)90103-6  0.448
1997 Mahanty S, Ravichandran M, Raman U, Jayaraman K, Kumaraswami V, Nutman TB. Regulation of parasite antigen-driven immune responses by interleukin-10 (IL-10) and IL-12 in lymphatic filariasis Infection and Immunity. 65: 1742-1747. PMID 9125556 DOI: 10.1128/Iai.65.5.1742-1747.1997  0.36
1997 Ravichandran M, Mahanty S, Kumaraswami V, Nutman TB, Jayaraman K. Elevated IL-10 mRNA expression and downregulation of Th1-type cytokines in microfilaraemic individuals with Wuchereria bancrofti infection Parasite Immunology. 19: 69-77. PMID 9076809 DOI: 10.1046/J.1365-3024.1997.D01-185.X  0.398
1997 McCarthy JS, Nutman TB. Perspective: prospects for development of vaccines against human helminth infections. The Journal of Infectious Diseases. 174: 1384-90. PMID 8940241 DOI: 10.1093/Infdis/174.6.1384  0.416
1997 Moore TA, Reynolds JC, Kenney RT, Johnston W, Nutman TB. Diethylcarbamazine-induced reversal of early lymphatic dysfunction in a patient with bancroftian filariasis: assessment with use of lymphoscintigraphy. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 23: 1007-11. PMID 8922794 DOI: 10.1093/Clinids/23.5.1007  0.367
1997 Stewart G, Boussinesq M, Coulson T, Elson L, Nutman T, Bradley J. Effect of onchocerciasis on the immune response to mycobacterial antigens Immunology Letters. 56: 212. DOI: 10.1016/S0165-2478(97)85846-4  0.327
1996 Garraud O, Nkenfou C, Bradley JE, Nutman TB. Differential regulation of antigen-specific IgG4 and IgE antibodies in response to recombinant filarial proteins International Immunology. 8: 1841-1848. PMID 8982768 DOI: 10.1093/Intimm/8.12.1841  0.355
1996 Cooper PJ, Guderian RH, Prakash D, Remick DG, Espinel I, Nutman TB, Taylor DW, Griffin GE. RANTES in onchocerciasis: Changes with ivermectin treatment Clinical and Experimental Immunology. 106: 462-467. PMID 8973613 DOI: 10.1046/J.1365-2249.1996.D01-868.X  0.349
1996 Elson LH, Days A, Calvopiña M, Paredes W, Araujo E, Guderian RH, Bradley JE, Nutman TB. In utero exposure to Onchocerca volvulus: relationship to subsequent infection intensity and cellular immune responsiveness. Infection and Immunity. 64: 5061-5. PMID 8945547 DOI: 10.1128/Iai.64.12.5061-5065.1996  0.383
1996 Mahanty S, Luke HE, Kumaraswami V, Narayanan PR, Vijayshekaran V, Nutman TB. Stage-specific induction of cytokines regulates the immune response in lymphatic filariasis. Experimental Parasitology. 84: 282-90. PMID 8932778 DOI: 10.1006/Expr.1996.0114  0.394
1996 McCarthy JS, Zhong M, Gopinath R, Ottesen EA, Williams SA, Nutman TB. Evaluation of a polymerase chain reaction-based assay for diagnosis of Wuchereria bancrofti infection. The Journal of Infectious Diseases. 173: 1510-4. PMID 8648232 DOI: 10.1093/Infdis/173.6.1510  0.345
1996 Hagan JB, Bartemes KR, Kita H, Ottesen EA, Awadzi K, Nutman TB, Gleich GJ. Elevations in granulocyte-macrophage colony-stimulating factor and interleukin-5 levels precede posttreatment eosinophilia in onchocerciasis. The Journal of Infectious Diseases. 173: 1277-80. PMID 8627086 DOI: 10.1093/Infdis/173.5.1277  0.34
1996 Nutman TB, Parredes W, Kubofcik J, Guderian RH. Polymerase chain reaction-based assessment after macrofilaricidal therapy in Onchocerca volvulus infection. The Journal of Infectious Diseases. 173: 773-6. PMID 8627052 DOI: 10.1093/Infdis/173.3.773  0.321
1996 Mahanty S, Mollis SN, Ravichandran M, Abrams JS, Kumaraswami V, Jayaraman K, Ottesen EA, Nutman TB. High levels of spontaneous and parasite antigen-driven interleukin-10 production are associated with antigen-specific hyporesponsiveness in human lymphatic filariasis. The Journal of Infectious Diseases. 173: 769-73. PMID 8627051 DOI: 10.1093/Infdis/173.3.769  0.377
1996 Gbakima AA, Nutman TB, Bradley JE, McReynolds LA, Winget MD, Hong Y, Scott AL. Immunoglobulin G subclass responses of children during infection with Onchocerca volvulus. Clinical and Diagnostic Laboratory Immunology. 3: 98-104. DOI: 10.1128/Cdli.3.1.98-104.1996  0.37
1996 RABIN R, FUSS I, PRUSSIN C, MCDYER J, GARRAUD O, NUTMAN T, FLEISHER T, SEDER R, STROBER W, HOLLAND S. 861 Characterization of an immunodeficiency manifest by severe viral skin infections, eczema, and asthma Journal of Allergy and Clinical Immunology. 97: 398-398. DOI: 10.1016/S0091-6749(96)81079-7  0.304
1996 Lobos E, Zahn R, Weiss N, Nutman TB. A Major Allergen of Lymphatic Filarial Nematodes Is a Parasite Homolog of the γ-Glutamyl Transpeptidase Molecular Medicine. 2: 712-724. DOI: 10.1007/Bf03401655  0.324
1995 Pandey JP, Elson LH, Sutherland SE, Guderian RH, Araujo E, Nutman TB. Immunoglobulin kappa chain allotypes (KM) in onchocerciasis. The Journal of Clinical Investigation. 96: 2732-4. PMID 8675641 DOI: 10.1172/Jci118341  0.329
1995 Stewart GR, Elson L, Araujo E, Guderian R, Nutman TB, Bradley JE. Isotype-specific characterization of antibody responses to Onchocerca volvulus in putatively immune individuals. Parasite Immunology. 17: 371-80. PMID 8552410 DOI: 10.1111/J.1365-3024.1995.Tb00904.X  0.335
1995 Elson LH, Calvopiña M, Paredes W, Araujo E, Bradley JE, Guderian RH, Nutman TB. Immunity to onchocerciasis: putative immune persons produce a Th1-like response to Onchocerca volvulus. The Journal of Infectious Diseases. 171: 652-8. PMID 7876612 DOI: 10.1093/Infdis/171.3.652  0.397
1995 Bradley JE, Elson L, Tree TI, Stewart G, Guderian R, Calvopiña M, Paredes W, Araujo E, Nutman TB. Resistance to Onchocerca volvulus: differential cellular and humoral responses to a recombinant antigen, OvMBP20/11. The Journal of Infectious Diseases. 172: 831-7. PMID 7658078 DOI: 10.1093/Infdis/172.3.831  0.375
1995 Gallin JI, Farber JM, Holland SM, Nutman TB. Interferon-gamma in the management of infectious diseases. Annals of Internal Medicine. 123: 216-24. PMID 7598304 DOI: 10.7326/0003-4819-123-3-199508010-00009  0.361
1995 Mahanty S, Nutman TB. Immunoregulation in human lymphatic filariasis: the role of interleukin 10 Parasite Immunology. 17: 385-392. PMID 7501419 DOI: 10.1111/J.1365-3024.1995.Tb00906.X  0.417
1994 Raghavan N, Freedman DO, Fitzgerald PC, Unnasch TR, Ottesen EA, Nutman TB. Cloning and characterization of a potentially protective chitinase-like recombinant antigen from Wuchereria bancrofti. Infection and Immunity. 62: 1901-8. PMID 8168956 DOI: 10.1128/Iai.62.5.1901-1908.1994  0.438
1994 Zimmerman PA, Guderian RH, Aruajo E, Elson L, Phadke P, Kubofcik J, Nutman TB. Polymerase chain reaction-based diagnosis of Onchocerca volvulus infection: improved detection of patients with onchocerciasis. The Journal of Infectious Diseases. 169: 686-9. PMID 8158053 DOI: 10.1093/Infdis/169.3.686  0.337
1994 Elson LH, Guderian RH, Araujo E, Bradley JE, Days A, Nutman TB. Immunity to onchocerciasis: identification of a putatively immune population in a hyperendemic area of Ecuador. The Journal of Infectious Diseases. 169: 588-94. PMID 8158031 DOI: 10.1093/Infdis/169.3.588  0.355
1994 McCarthy JS, Ottesen EA, Nutman TB. Onchocerciasis in endemic and nonendemic populations: differences in clinical presentation and immunologic findings. The Journal of Infectious Diseases. 170: 736-41. PMID 8077740 DOI: 10.1093/Infdis/170.3.736  0.362
1994 Steel C, Lujan-Trangay A, Gonzalez-Peralta C, Zea-Flores G, Nutman TB. Transient changes in cytokine profiles following ivermectin treatment of onchocerciasis. The Journal of Infectious Diseases. 170: 962-70. PMID 7930742 DOI: 10.1093/Infdis/170.4.962  0.346
1994 Horgan KJ, Tanaka Y, Luce GEG, Seventer GAV, Nutman TB, Shaw S. CD45RB expression defines two interconvertible subsets of human CD4+ T cells with memory function. European Journal of Immunology. 24: 1240-1243. PMID 7910140 DOI: 10.1002/Eji.1830240536  0.329
1994 Nutman TB, Zimmerman PA, Kubofcik J, Kostyu DD. A universally applicable diagnostic approach to filarial and other infections Parasitology Today. 10: 239-243. DOI: 10.1016/0169-4758(94)90127-9  0.394
1993 Limaye AP, Ottesen EA, Kumaraswami V, Abrams JS, Regunathan J, Vijayasekaran V, Jayaraman K, Nutman TB. Kinetics of serum and cellular interleukin-5 in posttreatment eosinophilia of patients with lymphatic filariasis. The Journal of Infectious Diseases. 167: 1396-400. PMID 8501330 DOI: 10.1093/Infdis/167.6.1396  0.328
1993 King CL, Mahanty S, Kumaraswami V, Abrams JS, Regunathan J, Jayaraman K, Ottesen EA, Nutman TB. Cytokine control of parasite-specific anergy in human lymphatic filariasis preferential induction of a regulatory T helper type 2 lymphocyte subset Journal of Clinical Investigation. 92: 1667-1673. PMID 8408619 DOI: 10.1172/Jci116752  0.394
1993 Mahanty S, Nutman TB. The biology of interleukin-5 and its receptor. Cancer Investigation. 11: 624-634. PMID 8402230 DOI: 10.3109/07357909309011681  0.394
1993 Modlin RL, Nutman TB. Type 2 cytokines and negative immune regulation in human infections Current Opinion in Immunology. 5: 511-517. PMID 8216926 DOI: 10.1016/0952-7915(93)90031-M  0.445
1993 Karp CL, el-Safi SH, Wynn TA, Satti MM, Kordofani AM, Hashim FA, Hag-Ali M, Neva FA, Nutman TB, Sacks DL. In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma. The Journal of Clinical Investigation. 91: 1644-8. PMID 8097208 DOI: 10.1172/Jci116372  0.391
1992 Nutman TB. Experimental infection of humans with filariae. Reviews of Infectious Diseases. 13: 1018-22. PMID 1962076 DOI: 10.1093/Clinids/13.5.1018  0.395
1992 King CL, Kumaraswami V, Poindexter RW, Kumari S, Jayaraman K, Alling DW, Ottesen EA, Nutman TB. Immunologic tolerance in lymphatic filariasis diminished parasite-specific T and B lymphocyte precursor frequency in the microfilaremic state Journal of Clinical Investigation. 89: 1403-1410. PMID 1569183 DOI: 10.1172/Jci115729  0.384
1992 Fargeas C, Wu CY, Nakajima T, Cox D, Nutman T, Delespesse G. Differential effect of transforming growth factor beta on the synthesis of Th1- and Th2-like lymphokines by human T lymphocytes. European Journal of Immunology. 22: 2173-6. PMID 1386318 DOI: 10.1002/Eji.1830220833  0.309
1991 Klion AD, Massougbodji A, Sadeler BC, Ottesen EA, Nutman TB. Loiasis in endemic and nonendemic populations: immunologically mediated differences in clinical presentation. The Journal of Infectious Diseases. 163: 1318-25. PMID 2037798 DOI: 10.1093/Infdis/163.6.1318  0.38
1991 Nutman TB, Steel C, Ward DJ, Zea-Flores G, Ottesen EA. Immunity to onchocerciasis: recognition of larval antigens by humans putatively immune to Onchocerca volvulus infection. The Journal of Infectious Diseases. 163: 1128-33. PMID 2019761 DOI: 10.1093/Infdis/163.5.1128  0.421
1991 Lobos E, Weiss N, Karam M, Taylor HR, Ottesen EA, Nutman TB. An immunogenic Onchocerca volvulus antigen: a specific and early marker of infection. Science (New York, N.Y.). 251: 1603-5. PMID 2011741 DOI: 10.1126/Science.2011741  0.403
1991 Limaye AP, Abrams JS, Silver JE, Awadzi K, Francis HF, Ottesen EA, Nutman TB. Interleukin-5 and the posttreatment eosinophilia in patients with onchocerciasis. The Journal of Clinical Investigation. 88: 1418-21. PMID 1918387 DOI: 10.1172/Jci115449  0.339
1991 King CL, Nutman TB. Regulation of the immune response in lymphatic filariasis and onchocerciasis Immunology Today. 12. PMID 1906280 DOI: 10.1016/S0167-5699(05)80016-7  0.44
1991 Raghavan N, McReynolds LA, Maina CV, Feinstone SM, Jayaraman K, Ottesen EA, Nutman TB. A recombinant clone of Wuchereria bancrofti with DNA specificity for human lymphatic filarial parasites. Molecular and Biochemical Parasitology. 47: 63-71. PMID 1857386 DOI: 10.1016/0166-6851(91)90148-Y  0.367
1991 Freedman DO, Lujan-Trangay A, Steel C, Gonzalez-Peralta C, Nutman TB. Immunoregulation in onchocerciasis. Functional and phenotypic abnormalities of lymphocyte subsets and changes with therapy. The Journal of Clinical Investigation. 88: 231-8. PMID 1829096 DOI: 10.1172/Jci115282  0.382
1991 Steel C, Lujan-Trangay A, Gonzalez-Peralta C, Zea-Flores G, Nutman TB. Immunologic responses to repeated ivermectin treatment in patients with onchocerciasis. The Journal of Infectious Diseases. 164: 581-7. PMID 1822959 DOI: 10.1093/Infdis/164.3.581  0.355
1991 Van Seventer GA, Newman W, Shimizu Y, Nutman TB, Tanaka Y, Horgan KJ, Gopal TV, Ennis E, O'Sullivan D, Grey H, Shaw S. Analysis of T cell stimulation by superantigen plus major histocompatibility complex class II molecules or by CD3 monoclonal antibody: Costimulation by purified adhesion ligands VCAM-1, ICAM-1, but not ELAM-1 Journal of Experimental Medicine. 174: 901-913. PMID 1717633 DOI: 10.1084/Jem.174.4.901  0.322
1991 King CL, Nutman TB. Regulation of the immune response in lymphatic filariasis and onchocerciasis Parasitology Today. 7: 54-58. DOI: 10.1016/0169-4758(91)90033-K  0.44
1990 King CL, Thyphronitis G, Nutman TB. Enumeration of IgE secreting B cells. A filter spot-ELISA Journal of Immunological Methods. 132: 37-43. PMID 2202765 DOI: 10.1016/0022-1759(90)90395-C  0.315
1990 Lee SJ, Francis HL, Awadzi K, Ottesen EA, Nutman TB. Changes in antibody profile after treatment of human onchocerciasis. The Journal of Infectious Diseases. 162: 529-33. PMID 2197344 DOI: 10.1093/Infdis/162.2.529  0.359
1990 Limaye AP, Abrams JS, Silver JE, Ottesen EA, Nutman TB. Regulation of parasite-induced eosinophilia: selectively increased interleukin 5 production in helminth-infected patients. The Journal of Experimental Medicine. 172: 399-402. PMID 2193099 DOI: 10.1084/Jem.172.1.399  0.383
1990 Lal RB, Kumaraswami V, Steel C, Nutman TB. Phosphocholine-containing antigens of Brugia malayi nonspecifically suppress lymphocyte function. The American Journal of Tropical Medicine and Hygiene. 42: 56-64. PMID 2137305 DOI: 10.4269/Ajtmh.1990.42.56  0.343
1990 King CL, Ottesen EA, Nutman TB. Cytokine regulation of antigen-driven immunoglobulin production in filarial parasite infections in humans Journal of Clinical Investigation. 85: 1810-1815. PMID 2112154 DOI: 10.1172/Jci114639  0.413
1990 Yanagihara Y, Sarfati M, Marsh D, Nutman T, Delespesse G. Serum level of IgE-binding factor (soluble CD23) in diseases associated with elevated IgE Clinical and Experimental Allergy. 20: 395-401. DOI: 10.1111/J.1365-2222.1990.Tb02800.X  0.306
1989 Arasu P, Nutman TB, Steel C, Mulligan MM, Abraham D, Tuan RS, Perler FB. Human T-cell stimulation, molecular characterization and in situ mRNA localization of a Brugia malayi recombinant antigen. Molecular and Biochemical Parasitology. 36: 223-31. PMID 2797061 DOI: 10.1016/0166-6851(89)90170-9  0.424
1989 Nutman TB, Vijayan VK, Pinkston P, Kumaraswami V, Steel C, Crystal RG, Ottesen EA. Tropical pulmonary eosinophilia: analysis of antifilarial antibody localized to the lung. The Journal of Infectious Diseases. 160: 1042-50. PMID 2685125 DOI: 10.1093/Infdis/160.6.1042  0.335
1989 Freedman DO, Nutman TB, Ottesen EA. Protective immunity in bancroftian filariasis. Selective recognition of a 43-kD larval stage antigen by infection-free individuals in an endemic area. The Journal of Clinical Investigation. 83: 14-22. PMID 2642916 DOI: 10.1172/Jci113850  0.415
1989 King CL, Gallin JI, Malech HL, Abramson SL, Nutman TB. Regulation of immunoglobulin production in hyperimmunoglobulin E recurrent-infection syndrome by interferon γ Proceedings of the National Academy of Sciences of the United States of America. 86: 10085-10089. PMID 2513574 DOI: 10.1073/Pnas.86.24.10085  0.35
1988 Nutman TB, Reese W, Poindexter RW, Ottesen EA. Immunologic correlates of the hyperresponsive syndrome of loiasis. The Journal of Infectious Diseases. 157: 544-50. PMID 3257785 DOI: 10.1093/Infdis/157.3.544  0.391
1988 Ward DJ, Nutman TB, Zea-Flores G, Portocarrero C, Lujan A, Ottesen EA. Onchocerciasis and immunity in humans: enhanced T cell responsiveness to parasite antigen in putatively immune individuals. The Journal of Infectious Diseases. 157: 536-43. PMID 3125261 DOI: 10.1093/Infdis/157.3.536  0.481
1987 Nutman TB, Ottesen EA, Ieng S, Samuels J, Kimball E, Lutkoski M, Zierdt WS, Gam A, Neva FA. Eosinophilia in Southeast Asian refugees: evaluation at a referral center. The Journal of Infectious Diseases. 155: 309-13. PMID 3805765 DOI: 10.1093/Infdis/155.2.309  0.378
1987 Maxwell C, Hussain R, Nutman TB, Poindexter RW, Little MD, Schad GA, Ottesen EA. The clinical and immunologic responses of normal human volunteers to low dose hookworm (Necator americanus) infection. The American Journal of Tropical Medicine and Hygiene. 37: 126-34. PMID 3605493 DOI: 10.4269/Ajtmh.1987.37.126  0.415
1987 Nutman TB, Kumaraswami V, Ottesen EA. Parasite-specific anergy in human filariasis. Insights after analysis of parasite antigen-driven lymphokine production. The Journal of Clinical Investigation. 79: 1516-23. PMID 3553242 DOI: 10.1172/Jci112982  0.413
1987 Nutman TB, Nash TE, Ottesen EA. Ivermectin in the successful treatment of a patient with Mansonella ozzardi infection. The Journal of Infectious Diseases. 156: 662-5. PMID 3305722 DOI: 10.1093/Infdis/156.4.662  0.358
1986 Nutman TB, Miller KD, Mulligan M, Ottesen EA. Loa loa infection in temporary residents of endemic regions: recognition of a hyperresponsive syndrome with characteristic clinical manifestations. The Journal of Infectious Diseases. 154: 10-8. PMID 3458832 DOI: 10.1093/Infdis/154.1.10  0.344
1984 Nutman TB, Ottesen EA, Fauci AS, Volkman DJ. Parasite antigen-specific human T cell lines and clones. Major histocompatibility complex restriction and B cell helper function. The Journal of Clinical Investigation. 73: 1754-62. PMID 6233302 DOI: 10.1172/Jci111384  0.352
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