| Year |
Citation |
Score |
| 2023 |
Kumar S, Sega S, Lynn-Barbe JK, Harris DL, Koehn JT, Crans DC, Crick DC. Proline Dehydrogenase and Pyrroline 5 Carboxylate Dehydrogenase from Evidence for Substrate Channeling. Pathogens (Basel, Switzerland). 12. PMID 37764979 DOI: 10.3390/pathogens12091171 |
0.326 |
|
| 2023 |
Berg K, Hegde P, Pujari V, Brinkmann M, Wilkins DZ, Parish T, Crick DC, Aldrich CC. SAR study of piperidine derivatives as inhibitors of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis. European Journal of Medicinal Chemistry. 249: 115125. PMID 36682292 DOI: 10.1016/j.ejmech.2023.115125 |
0.359 |
|
| 2021 |
Tran W, Kusay AS, Hawkins PME, Cheung CY, Nagalingam G, Pujari V, Ford DJ, Stoye A, Ochoa JL, Audette RE, Hortle E, Oehlers SH, Charman SA, Linington RG, Rubin EJ, ... ... Crick DC, et al. Synthetic Sansanmycin Analogues as Potent Translocase I Inhibitors. Journal of Medicinal Chemistry. 64: 17326-17345. PMID 34845906 DOI: 10.1021/acs.jmedchem.1c01407 |
0.321 |
|
| 2019 |
Dhiman RK, Pujari V, Kincaid JM, Ikeh MA, Parish T, Crick DC. Characterization of MenA (isoprenyl diphosphate:1,4-dihydroxy-2-naphthoate isoprenyltransferase) from Mycobacterium tuberculosis. Plos One. 14: e0214958. PMID 30978223 DOI: 10.1371/journal.pone.0214958 |
0.6 |
|
| 2018 |
Islam MN, Hitchings R, Kumar S, Fontes FL, Lott JS, Kruh-Garcia NA, Crick DC. The mechanism of fluorinated anthranilate-induced growth inhibition in Mycobacterium tuberculosis. Acs Infectious Diseases. PMID 30406991 DOI: 10.1021/acsinfecdis.8b00092 |
0.432 |
|
| 2018 |
Upadhyay A, Kumar S, Rooker SA, Koehn JT, Crans DC, McNeil MR, Lott JS, Crick DC. Mycobacterial MenJ, an oxidoreductase involved in menaquinone biosynthesis. Acs Chemical Biology. PMID 30091899 DOI: 10.1021/Acschembio.8B00402 |
0.443 |
|
| 2017 |
Tran AT, Watson EE, Pujari V, Conroy T, Dowman LJ, Giltrap AM, Pang A, Wong WR, Linington RG, Mahapatra S, Saunders J, Charman SA, West NP, Bugg TD, Tod J, ... ... Crick DC, et al. Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis. Nature Communications. 8: 14414. PMID 28248311 DOI: 10.1038/Ncomms14414 |
0.324 |
|
| 2015 |
Feng X, Zhu W, Schurig-Briccio LA, Lindert S, Shoen C, Hitchings R, Li J, Wang Y, Baig N, Zhou T, Kim BK, Crick DC, Cynamon M, McCammon JA, Gennis RB, et al. Antiinfectives targeting enzymes and the proton motive force. Proceedings of the National Academy of Sciences of the United States of America. 112: E7073-82. PMID 26644565 DOI: 10.1073/Pnas.1521988112 |
0.331 |
|
| 2015 |
Upadhyay A, Fontes FL, Gonzalez-Juarrero M, McNeil MR, Crans DC, Jackson M, Crick DC. Partial Saturation of Menaquinone in Mycobacterium tuberculosis: Function and Essentiality of a Novel Reductase, MenJ. Acs Central Science. 1: 292-302. PMID 26436137 DOI: 10.1021/Acscentsci.5B00212 |
0.394 |
|
| 2014 |
Li W, Upadhyay A, Fontes FL, North EJ, Wang Y, Crans DC, Grzegorzewicz AE, Jones V, Franzblau SG, Lee RE, Crick DC, Jackson M. Novel insights into the mechanism of inhibition of MmpL3, a target of multiple pharmacophores in Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 58: 6413-23. PMID 25136022 DOI: 10.1128/Aac.03229-14 |
0.421 |
|
| 2014 |
Li K, Schurig-Briccio LA, Feng X, Upadhyay A, Pujari V, Lechartier B, Fontes FL, Yang H, Rao G, Zhu W, Gulati A, No JH, Cintra G, Bogue S, Liu YL, ... ... Crick DC, et al. Multitarget drug discovery for tuberculosis and other infectious diseases. Journal of Medicinal Chemistry. 57: 3126-39. PMID 24568559 DOI: 10.1021/Jm500131S |
0.302 |
|
| 2014 |
Chan HC, Feng X, Ko TP, Huang CH, Hu Y, Zheng Y, Bogue S, Nakano C, Hoshino T, Zhang L, Lv P, Liu W, Crick DC, Liang PH, Wang AH, et al. Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. Journal of the American Chemical Society. 136: 2892-6. PMID 24475925 DOI: 10.1021/Ja413127V |
0.347 |
|
| 2013 |
Ishizaki Y, Hayashi C, Inoue K, Igarashi M, Takahashi Y, Pujari V, Crick DC, Brennan PJ, Nomoto A. Inhibition of the first step in synthesis of the mycobacterial cell wall core, catalyzed by the GlcNAc-1-phosphate transferase WecA, by the novel caprazamycin derivative CPZEN-45. The Journal of Biological Chemistry. 288: 30309-19. PMID 23986448 DOI: 10.1074/Jbc.M113.492173 |
0.312 |
|
| 2013 |
Mahapatra S, Piechota C, Gil F, Ma Y, Huang H, Scherman MS, Jones V, Pavelka MS, Moniz-Pereira J, Pimentel M, McNeil MR, Crick DC. Mycobacteriophage Ms6 LysA: a peptidoglycan amidase and a useful analytical tool. Applied and Environmental Microbiology. 79: 768-73. PMID 23160121 DOI: 10.1128/Aem.02263-12 |
0.34 |
|
| 2012 |
Debnath J, Siricilla S, Wan B, Crick DC, Lenaerts AJ, Franzblau SG, Kurosu M. Discovery of selective menaquinone biosynthesis inhibitors against Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 55: 3739-55. PMID 22449052 DOI: 10.1021/Jm201608G |
0.386 |
|
| 2011 |
Zhang J, Angala SK, Pramanik PK, Li K, Crick DC, Liav A, Jozwiak A, Swiezewska E, Jackson M, Chatterjee D. Reconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donors. Acs Chemical Biology. 6: 819-28. PMID 21595486 DOI: 10.1021/Cb200091M |
0.338 |
|
| 2011 |
Bhamidi S, Scherman MS, Jones V, Crick DC, Belisle JT, Brennan PJ, McNeil MR. Detailed structural and quantitative analysis reveals the spatial organization of the cell walls of in vivo grown Mycobacterium leprae and in vitro grown Mycobacterium tuberculosis. The Journal of Biological Chemistry. 286: 23168-77. PMID 21555513 DOI: 10.1074/Jbc.M110.210534 |
0.373 |
|
| 2011 |
Sartain MJ, Dick DL, Rithner CD, Crick DC, Belisle JT. Lipidomic analyses of Mycobacterium tuberculosis based on accurate mass measurements and the novel "Mtb LipidDB". Journal of Lipid Research. 52: 861-72. PMID 21285232 DOI: 10.1194/Jlr.M010363 |
0.313 |
|
| 2010 |
Ryan GJ, Hoff DR, Driver ER, Voskuil MI, Gonzalez-Juarrero M, Basaraba RJ, Crick DC, Spencer JS, Lenaerts AJ. Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach. Plos One. 5: e11108. PMID 20559431 DOI: 10.1371/Journal.Pone.0011108 |
0.395 |
|
| 2010 |
Narayanasamy P, Eoh H, Brennan PJ, Crick DC. Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate and kinetic studies of Mycobacterium tuberculosis IspF. Chemistry & Biology. 17: 117-22. PMID 20189102 DOI: 10.1016/j.chembiol.2010.01.013 |
0.335 |
|
| 2010 |
Brown AC, Eberl M, Crick DC, Jomaa H, Parish T. The nonmevalonate pathway of isoprenoid biosynthesis in Mycobacterium tuberculosis is essential and transcriptionally regulated by Dxs. Journal of Bacteriology. 192: 2424-33. PMID 20172995 DOI: 10.1128/JB.01402-09 |
0.347 |
|
| 2009 |
Kurosu M, Crick DC. MenA is a promising drug target for developing novel lead molecules to combat Mycobacterium tuberculosis. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 5: 197-207. PMID 19275719 DOI: 10.2174/157340609787582882 |
0.337 |
|
| 2009 |
Dhiman RK, Mahapatra S, Slayden RA, Boyne ME, Lenaerts A, Hinshaw JC, Angala SK, Chatterjee D, Biswas K, Narayanasamy P, Kurosu M, Crick DC. Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non-replicating persistence. Molecular Microbiology. 72: 85-97. PMID 19220750 DOI: 10.1111/J.1365-2958.2009.06625.X |
0.339 |
|
| 2009 |
Eoh H, Brennan PJ, Crick DC. The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target. Tuberculosis (Edinburgh, Scotland). 89: 1-11. PMID 18793870 DOI: 10.1016/j.tube.2008.07.004 |
0.383 |
|
| 2008 |
Grzegorzewicz AE, Ma Y, Jones V, Crick D, Liav A, McNeil MR. Development of a microtitre plate-based assay for lipid-linked glycosyltransferase products using the mycobacterial cell wall rhamnosyltransferase WbbL. Microbiology (Reading, England). 154: 3724-30. PMID 19047740 DOI: 10.1099/Mic.0.2008/023366-0 |
0.438 |
|
| 2008 |
Noike M, Ambo T, Kikuchi S, Suzuki T, Yamashita S, Takahashi S, Kurokawa H, Mahapatra S, Crick DC, Koyama T. Product chain-length determination mechanism of Z,E-farnesyl diphosphate synthase. Biochemical and Biophysical Research Communications. 377: 17-22. PMID 18790692 DOI: 10.1016/j.bbrc.2008.09.014 |
0.343 |
|
| 2008 |
Mao J, Eoh H, He R, Wang Y, Wan B, Franzblau SG, Crick DC, Kozikowski AP. Structure-activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase. Bioorganic & Medicinal Chemistry Letters. 18: 5320-3. PMID 18783951 DOI: 10.1016/J.Bmcl.2008.08.034 |
0.356 |
|
| 2008 |
Wang W, Dong C, McNeil M, Kaur D, Mahapatra S, Crick DC, Naismith JH. The structural basis of chain length control in Rv1086. Journal of Molecular Biology. 381: 129-40. PMID 18597781 DOI: 10.1016/J.Jmb.2008.05.060 |
0.56 |
|
| 2008 |
Zhang W, Jones VC, Scherman MS, Mahapatra S, Crick D, Bhamidi S, Xin Y, McNeil MR, Ma Y. Expression, essentiality, and a microtiter plate assay for mycobacterial GlmU, the bifunctional glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1-phosphate uridyltransferase. The International Journal of Biochemistry & Cell Biology. 40: 2560-71. PMID 18573680 DOI: 10.1016/J.Biocel.2008.05.003 |
0.615 |
|
| 2008 |
Mahapatra S, Crick DC, McNeil MR, Brennan PJ. Unique structural features of the peptidoglycan of Mycobacterium leprae. Journal of Bacteriology. 190: 655-61. PMID 18024514 DOI: 10.1128/JB.00982-07 |
0.384 |
|
| 2007 |
Eoh H, Brown AC, Buetow L, Hunter WN, Parish T, Kaur D, Brennan PJ, Crick DC. Characterization of the Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol synthase: potential for drug development. Journal of Bacteriology. 189: 8922-7. PMID 17921290 DOI: 10.1128/JB.00925-07 |
0.416 |
|
| 2007 |
Brennan PJ, Crick DC. The cell-wall core of Mycobacterium tuberculosis in the context of drug discovery. Current Topics in Medicinal Chemistry. 7: 475-88. PMID 17346193 DOI: 10.2174/156802607780059763 |
0.337 |
|
| 2006 |
Mikusová K, Belánová M, Korduláková J, Honda K, McNeil MR, Mahapatra S, Crick DC, Brennan PJ. Identification of a novel galactosyl transferase involved in biosynthesis of the mycobacterial cell wall. Journal of Bacteriology. 188: 6592-8. PMID 16952951 DOI: 10.1128/JB.00489-06 |
0.361 |
|
| 2006 |
Kaur D, Berg S, Dinadayala P, Gicquel B, Chatterjee D, McNeil MR, Vissa VD, Crick DC, Jackson M, Brennan PJ. Biosynthesis of mycobacterial lipoarabinomannan: role of a branching mannosyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 103: 13664-9. PMID 16945913 DOI: 10.1073/Pnas.0603049103 |
0.425 |
|
| 2006 |
Khasnobis S, Zhang J, Angala SK, Amin AG, McNeil MR, Crick DC, Chatterjee D. Characterization of a specific arabinosyltransferase activity involved in mycobacterial arabinan biosynthesis. Chemistry & Biology. 13: 787-95. PMID 16873027 DOI: 10.1016/J.Chembiol.2006.05.016 |
0.32 |
|
| 2006 |
Dinadayala P, Kaur D, Berg S, Amin AG, Vissa VD, Chatterjee D, Brennan PJ, Crick DC. Genetic basis for the synthesis of the immunomodulatory mannose caps of lipoarabinomannan in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 281: 20027-35. PMID 16704981 DOI: 10.1074/Jbc.M603395200 |
0.345 |
|
| 2005 |
Dhiman RK, Schaeffer ML, Bailey AM, Testa CA, Scherman H, Crick DC. 1-Deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Mycobacterium tuberculosis: towards understanding mycobacterial resistance to fosmidomycin. Journal of Bacteriology. 187: 8395-402. PMID 16321944 DOI: 10.1128/Jb.187.24.8395-8402.2005 |
0.454 |
|
| 2005 |
VanderVen BC, Harder JD, Crick DC, Belisle JT. Export-mediated assembly of mycobacterial glycoproteins parallels eukaryotic pathways. Science (New York, N.Y.). 309: 941-3. PMID 16081738 DOI: 10.1126/Science.1114347 |
0.324 |
|
| 2005 |
Huang H, Scherman MS, D'Haeze W, Vereecke D, Holsters M, Crick DC, McNeil MR. Identification and active expression of the Mycobacterium tuberculosis gene encoding 5-phospho-{alpha}-d-ribose-1-diphosphate: decaprenyl-phosphate 5-phosphoribosyltransferase, the first enzyme committed to decaprenylphosphoryl-d-arabinose synthesis. The Journal of Biological Chemistry. 280: 24539-43. PMID 15878857 DOI: 10.1074/jbc.M504068200 |
0.461 |
|
| 2004 |
Kaur D, Brennan PJ, Crick DC. Decaprenyl diphosphate synthesis in Mycobacterium tuberculosis. Journal of Bacteriology. 186: 7564-70. PMID 15516568 DOI: 10.1128/JB.186.22.7564-7570.2004 |
0.742 |
|
| 2004 |
Dhiman RK, Schulbach MC, Mahapatra S, Baulard AR, Vissa V, Brennan PJ, Crick DC. Identification of a novel class of omega,E,E-farnesyl diphosphate synthase from Mycobacterium tuberculosis. Journal of Lipid Research. 45: 1140-7. PMID 15060088 DOI: 10.1194/Jlr.M400047-Jlr200 |
0.708 |
|
| 2003 |
Phetsuksiri B, Jackson M, Scherman H, McNeil M, Besra GS, Baulard AR, Slayden RA, DeBarber AE, Barry CE, Baird MS, Crick DC, Brennan PJ. Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis. The Journal of Biological Chemistry. 278: 53123-30. PMID 14559907 DOI: 10.1074/Jbc.M311209200 |
0.328 |
|
| 2002 |
Bailey AM, Mahapatra S, Brennan PJ, Crick DC. Identification, cloning, purification, and enzymatic characterization of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase. Glycobiology. 12: 813-20. PMID 12499403 DOI: 10.1093/glycob/cwf100 |
0.45 |
|
| 2002 |
Maeda Y, Makino M, Crick DC, Mahapatra S, Srisungnam S, Takii T, Kashiwabara Y, Brennan PJ. Novel 33-kilodalton lipoprotein from Mycobacterium leprae. Infection and Immunity. 70: 4106-11. PMID 12117918 DOI: 10.1128/IAI.70.8.4106-4111.2002 |
0.32 |
|
| 2002 |
Gurcha SS, Baulard AR, Kremer L, Locht C, Moody DB, Muhlecker W, Costello CE, Crick DC, Brennan PJ, Besra GS. Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis. The Biochemical Journal. 365: 441-50. PMID 11931640 DOI: 10.1042/Bj20020107 |
0.437 |
|
| 2001 |
Crick DC, Mahapatra S, Brennan PJ. Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis. Glycobiology. 11: 107R-118R. PMID 11555614 |
0.491 |
|
| 2001 |
Schulbach MC, Mahapatra S, Macchia M, Barontini S, Papi C, Minutolo F, Bertini S, Brennan PJ, Crick DC. Purification, enzymatic characterization, and inhibition of the Z-farnesyl diphosphate synthase from Mycobacterium tuberculosis. The Journal of Biological Chemistry. 276: 11624-30. PMID 11152452 DOI: 10.1074/Jbc.M007168200 |
0.704 |
|
| 2000 |
Mahapatra S, Crick DC, Brennan PJ. Comparison of the UDP-N-acetylmuramate:L-alanine ligase enzymes from Mycobacterium tuberculosis and Mycobacterium leprae. Journal of Bacteriology. 182: 6827-30. PMID 11073931 DOI: 10.1128/JB.182.23.6827-6830.2000 |
0.394 |
|
| 2000 |
Crick DC, Schulbach MC, Zink EE, Macchia M, Barontini S, Besra GS, Brennan PJ. Polyprenyl phosphate biosynthesis in Mycobacterium tuberculosis and Mycobacterium smegmatis. Journal of Bacteriology. 182: 5771-8. PMID 11004176 DOI: 10.1128/Jb.182.20.5771-5778.2000 |
0.702 |
|
| 2000 |
Mikusová K, Yagi T, Stern R, McNeil MR, Besra GS, Crick DC, Brennan PJ. Biosynthesis of the galactan component of the mycobacterial cell wall. The Journal of Biological Chemistry. 275: 33890-7. PMID 10934214 DOI: 10.1074/jbc.M006875200 |
0.313 |
|
| 2000 |
Jackson M, Crick DC, Brennan PJ. Phosphatidylinositol is an essential phospholipid of mycobacteria. The Journal of Biological Chemistry. 275: 30092-9. PMID 10889206 DOI: 10.1074/jbc.M004658200 |
0.374 |
|
| 2000 |
Schulbach MC, Brennan PJ, Crick DC. Identification of a short (C15) chain Z-isoprenyl diphosphate synthase and a homologous long (C50) chain isoprenyl diphosphate synthase in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 275: 22876-81. PMID 10816587 DOI: 10.1074/Jbc.M003194200 |
0.702 |
|
| 1999 |
Pathak AK, Besra GS, Crick D, Maddry JA, Morehouse CB, Suling WJ, Reynolds RC. Studies on beta-D-Gal(f)-(1-->4)-alpha-L-Rha(p) octyl analogues as substrates for mycobacterial galactosyl transferase activity. Bioorganic & Medicinal Chemistry. 7: 2407-13. PMID 10632050 DOI: 10.1016/S0968-0896(99)00199-6 |
0.363 |
|
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