Year |
Citation |
Score |
2020 |
Miyake T, Farley CM, Neubauer BE, Beddow TP, Hoenen T, Engel DA. Ebola virus inclusion body formation and RNA synthesis are controlled by a novel domain of NP interacting with VP35. Journal of Virology. PMID 32493824 DOI: 10.1128/Jvi.02100-19 |
0.393 |
|
2019 |
Patnaik S, Basu D, Southall N, Dehdashti S, Wan KK, Zheng W, Ferrer M, Taylor M, Engel DA, Marugan JJ. Identification, design and synthesis of novel pyrazolopyridine influenza virus nonstructural protein 1 antagonists. Bioorganic & Medicinal Chemistry Letters. PMID 30852083 DOI: 10.1016/J.Bmcl.2019.02.027 |
0.512 |
|
2018 |
Radwańska MJ, Jaskółowski M, Davydova E, Derewenda U, Miyake T, Engel DA, Kossiakoff AA, Derewenda ZS. The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab. Acta Crystallographica. Section D, Structural Biology. 74: 681-689. PMID 29968677 DOI: 10.1107/S2059798318007878 |
0.352 |
|
2016 |
Baker LE, Ellena JF, Handing KB, Derewenda U, Utepbergenov D, Engel DA, Derewenda ZS. Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses. Acta Crystallographica. Section D, Structural Biology. 72: 49-58. PMID 26894534 DOI: 10.1107/S2059798315021439 |
0.443 |
|
2014 |
Dziuba?ska PJ, Derewenda U, Ellena JF, Engel DA, Derewenda ZS. The structure of the C-terminal domain of the Zaire ebolavirus nucleoprotein. Acta Crystallographica. Section D, Biological Crystallography. 70: 2420-9. PMID 25195755 DOI: 10.1107/S1399004714014710 |
0.419 |
|
2014 |
Derewenda Z, Dziubanska P, Derewenda U, Ellena J, Haley K, Engel D. The crystal structure of the C-terminal domain of the Ebola virus nucleoprotein Acta Crystallographica Section a Foundations and Advances. 70: C1594-C1594. DOI: 10.1107/S2053273314084058 |
0.454 |
|
2013 |
Suomalainen M, Luisoni S, Boucke K, Bianchi S, Engel DA, Greber UF. A direct and versatile assay measuring membrane penetration of adenovirus in single cells. Journal of Virology. 87: 12367-79. PMID 24027314 DOI: 10.1128/Jvi.01833-13 |
0.45 |
|
2013 |
Engel DA. The influenza virus NS1 protein as a therapeutic target. Antiviral Research. 99: 409-16. PMID 23796981 DOI: 10.1016/J.Antiviral.2013.06.005 |
0.524 |
|
2013 |
Gupta A, Jha S, Engel DA, Ornelles DA, Dutta A. Tip60 degradation by adenovirus relieves transcriptional repression of viral transcriptional activator EIA. Oncogene. 32: 5017-25. PMID 23178490 DOI: 10.1038/Onc.2012.534 |
0.503 |
|
2012 |
Jablonski JJ, Basu D, Engel DA, Geysen HM. Design, synthesis, and evaluation of novel small molecule inhibitors of the influenza virus protein NS1. Bioorganic & Medicinal Chemistry. 20: 487-97. PMID 22099257 DOI: 10.1016/J.Bmc.2011.10.026 |
0.467 |
|
2011 |
Frieman M, Basu D, Matthews K, Taylor J, Jones G, Pickles R, Baric R, Engel DA. Yeast based small molecule screen for inhibitors of SARS-CoV. Plos One. 6: e28479. PMID 22164298 DOI: 10.1371/Journal.Pone.0028479 |
0.471 |
|
2011 |
Schaack J, Qiao L, Walkiewicz MP, Stonehouse M, Engel DA, Vazquez-Torres A, Nordeen SK, Shao J, Moorhead JW. Insertion of CTCF-binding sites into a first-generation adenovirus vector reduces the innate inflammatory response and prolongs transgene expression. Virology. 412: 136-45. PMID 21272906 DOI: 10.1016/J.Virol.2010.12.053 |
0.695 |
|
2011 |
Hagan KA, Reedy CR, Uchimoto ML, Basu D, Engel DA, Landers JP. An integrated, valveless system for microfluidic purification and reverse transcription-PCR amplification of RNA for detection of infectious agents. Lab On a Chip. 11: 957-61. PMID 21152489 DOI: 10.1039/C0Lc00136H |
0.334 |
|
2011 |
Walkiewicz MP, Basu D, Jablonski JJ, Geysen HM, Engel DA. Novel inhibitor of influenza non-structural protein 1 blocks multi-cycle replication in an RNase L-dependent manner. The Journal of General Virology. 92: 60-70. PMID 20881091 DOI: 10.1099/Vir.0.025015-0 |
0.721 |
|
2009 |
Walkiewicz MP, Morral N, Engel DA. Accurate single-day titration of adenovirus vectors based on equivalence of protein VII nuclear dots and infectious particles. Journal of Virological Methods. 159: 251-8. PMID 19406166 DOI: 10.1016/J.Jviromet.2009.04.010 |
0.709 |
|
2009 |
Basu D, Walkiewicz MP, Frieman M, Baric RS, Auble DT, Engel DA. Novel influenza virus NS1 antagonists block replication and restore innate immune function. Journal of Virology. 83: 1881-91. PMID 19052087 DOI: 10.1128/Jvi.01805-08 |
0.724 |
|
2008 |
Rao M, Casimiro MC, Lisanti MP, D'Amico M, Wang C, Shirley LA, Leader JE, Liu M, Stallcup M, Engel DA, Murphy DJ, Pestell RG. Inhibition of cyclin D1 gene transcription by Brg-1. Cell Cycle (Georgetown, Tex.). 7: 647-55. PMID 18239461 DOI: 10.4161/Cc.7.5.5446 |
0.559 |
|
2007 |
Chen J, Morral N, Engel DA. Transcription releases protein VII from adenovirus chromatin. Virology. 369: 411-22. PMID 17888479 DOI: 10.1016/J.Virol.2007.08.012 |
0.498 |
|
2005 |
Xue Y, Johnson JS, Ornelles DA, Lieberman J, Engel DA. Adenovirus protein VII functions throughout early phase and interacts with cellular proteins SET and pp32. Journal of Virology. 79: 2474-83. PMID 15681448 DOI: 10.1128/Jvi.79.4.2474-2483.2005 |
0.483 |
|
2004 |
Johnson JS, Osheim YN, Xue Y, Emanuel MR, Lewis PW, Bankovich A, Beyer AL, Engel DA. Adenovirus protein VII condenses DNA, represses transcription, and associates with transcriptional activator E1A. Journal of Virology. 78: 6459-68. PMID 15163739 DOI: 10.1128/Jvi.78.12.6459-6468.2004 |
0.489 |
|
2003 |
Spector DJ, Johnson JS, Baird NL, Engel DA. Adenovirus type 5 DNA-protein complexes from formaldehyde cross-linked cells early after infection. Virology. 312: 204-12. PMID 12890633 DOI: 10.1016/S0042-6822(03)00194-6 |
0.466 |
|
2002 |
Kulesza CA, Van Buskirk HA, Cole MD, Reese JC, Smith MM, Engel DA. Adenovirus E1A requires the yeast SAGA histone acetyltransferase complex and associates with SAGA components Gcn5 and Tra1. Oncogene. 21: 1411-22. PMID 11857084 DOI: 10.1038/Sj.Onc.1205201 |
0.701 |
|
1999 |
Murphy DJ, Hardy S, Engel DA. Human SWI-SNF component BRG1 represses transcription of the c-fos gene. Molecular and Cellular Biology. 19: 2724-33. PMID 10082538 DOI: 10.1128/Mcb.19.4.2724 |
0.608 |
|
1996 |
Miller ME, Cairns BR, Levinson RS, Yamamoto KR, Engel DA, Smith MM. Adenovirus E1A specifically blocks SWI/SNF-dependent transcriptional activation. Molecular and Cellular Biology. 16: 5737-43. PMID 8816487 DOI: 10.1128/Mcb.16.10.5737 |
0.422 |
|
1995 |
Gedrich RW, Engel DA. Identification of a novel E1A response element in the mouse c-fos promoter. Journal of Virology. 69: 2333-40. PMID 7884879 |
0.314 |
|
1995 |
Zhou Q, Gedrich RW, Engel DA. Transcriptional repression of the c-fos gene by YY1 is mediated by a direct interaction with ATF/CREB. Journal of Virology. 69: 4323-30. PMID 7769693 |
0.319 |
|
1995 |
Zhou Q, Engel DA. Adenovirus E1A243 disrupts the ATF/CREB-YY1 complex at the mouse c-fos promoter. Journal of Virology. 69: 7402-9. PMID 7494244 |
0.362 |
|
1992 |
Gedrich RW, Bayley ST, Engel DA. Induction of AP-1 DNA-binding activity and c-fos mRNA by the adenovirus 243R E1A protein and cyclic AMP requires domains necessary for transformation. Journal of Virology. 66: 5849-59. PMID 1326646 |
0.327 |
|
1991 |
Engel DA, Muller U, Gedrich RW, Eubanks JS, Shenk T. Induction of c-fos mRNA and AP-1 DNA-binding activity by cAMP in cooperation with either the adenovirus 243- or the adenovirus 289-amino acid E1A protein. Proceedings of the National Academy of Sciences of the United States of America. 88: 3957-61. PMID 1850843 |
0.366 |
|
1989 |
Müller U, Roberts MP, Engel DA, Doerfler W, Shenk T. Induction of transcription factor AP-1 by adenovirus E1A protein and cAMP. Genes & Development. 3: 1991-2002. PMID 2559873 DOI: 10.1101/Gad.3.12A.1991 |
0.359 |
|
1988 |
Engel DA, Hardy S, Shenk T. cAMP acts in synergy with E1A protein to activate transcription of the adenovirus early genes E4 and E1A. Genes & Development. 2: 1517-28. PMID 2850966 |
0.368 |
|
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