Jason Gertz, Ph.D. - Publications

Affiliations: 
2008 Washington University, Saint Louis, St. Louis, MO 
Area:
Bioinformatics, Molecular Biology

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Perovanovic J, Wu Y, Abewe H, Shen Z, Hughes EP, Gertz J, Chandrasekharan MB, Tantin D. Oct1 cooperates with the Smad family of transcription factors to promote mesodermal lineage specification. Science Signaling. 16: eadd5750. PMID 37071732 DOI: 10.1126/scisignal.add5750  0.316
2020 Camolotto SA, Belova VK, Torre-Healy L, Vahrenkamp JM, Berrett KC, Conway H, Shea J, Stubben C, Moffitt R, Gertz J, Snyder EL. Reciprocal regulation of pancreatic ductal adenocarcinoma growth and molecular subtype by HNF4α and SIX1/4. Gut. PMID 32826305 DOI: 10.1136/Gutjnl-2020-321316  0.328
2020 Carleton JB, Ginley-Hidinger M, Berrett KC, Layer RM, Quinlan AR, Gertz J. Regulatory sharing between estrogen receptor α bound enhancers. Nucleic Acids Research. PMID 32479598 DOI: 10.1093/Nar/Gkaa454  0.42
2020 Ireland AS, Micinski AM, Kastner DW, Guo B, Wait SJ, Spainhower KB, Conley CC, Chen OS, Guthrie MR, Soltero D, Qiao Y, Huang X, Tarapcsák S, Devarakonda S, Chalishazar MD, ... Gertz J, et al. MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate. Cancer Cell. PMID 32473656 DOI: 10.1016/J.Ccell.2020.05.001  0.323
2020 Farhang N, Davis B, Weston J, Ginley-Hidinger M, Gertz J, Bowles RD. Synergistic CRISPRa-Regulated Chondrogenic ECM Deposition Without Exogenous Growth Factors. Tissue Engineering. Part A. PMID 32460686 DOI: 10.1089/Ten.Tea.2020.0062  0.329
2020 Rodriguez AC, Vahrenkamp JM, Berrett KC, Clark KA, Guillen KP, Scherer SD, Yang CH, Welm BE, Janát-Amsbury MM, Graves BJ, Gertz J. ETV4 Is Necessary for Estrogen Signaling and Growth in Endometrial Cancer Cells. Cancer Research. PMID 32046982 DOI: 10.1158/0008-5472.Can-19-1382  0.36
2020 Berg JA, Belyeu JR, Morgan JT, Ouyang Y, Bott AJ, Quinlan AR, Gertz J, Rutter J. XPRESSyourself: Enhancing, standardizing, and automating ribosome profiling computational analyses yields improved insight into data. Plos Computational Biology. 16: e1007625. PMID 32004313 DOI: 10.1371/Journal.Pcbi.1007625  0.334
2020 Mollaoglu G, Jones A, Wait S, Mukhopadhyay A, Jeong S, Arya R, Camolotto S, Mosbruger T, Stubben C, Conley C, Bhutkar A, Vahrenkamp J, Berrett K, Cessna M, Lane T, ... ... Gertz J, et al. Abstract B72: Lineage specifiers SOX2 and NKX2-1 inversely regulate tumor cell fate and neutrophil recruitment in lung cancer Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-B72  0.345
2020 Richer JK, Williams MM, Spoelstra NS, Arnesen S, Christenson JL, O’Neill K, Reese JM, Blanchard ZD, Hanamura T, Jacobsen BM, Gertz J, Elias A. Abstract P6-04-13: Preclinical and clinical analyses of estrogen receptor alpha mutant metastatic breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P6-04-13  0.325
2020 Li Z, Levine KM, Arneson S, Berrett KC, Priedigkeit NM, Bahreini A, Chen J, Zhu L, Carroll JS, Tseng GC, Lucas PC, Atkinson JM, Gertz J, Lee AV, Oesterreich S. Abstract 4917: Estrogen receptor D538G mutation promotes cell migration via hyperactivation of Wnt signaling pathway Cancer Research. 80: 4917-4917. DOI: 10.1158/1538-7445.Am2020-4917  0.342
2019 Ginley-Hidinger M, Carleton JB, Rodriguez AC, Berrett KC, Gertz J. Sufficiency analysis of estrogen responsive enhancers using synthetic activators. Life Science Alliance. 2. PMID 31570515 DOI: 10.26508/lsa.201900497  0.333
2019 Blanchard Z, Vahrenkamp JM, Berrett KC, Arnesen S, Gertz J. Estrogen-independent molecular actions of mutant estrogen receptor 1 in endometrial cancer. Genome Research. PMID 31362937 DOI: 10.1101/Gr.244780.118  0.325
2019 Reese J, Babbs B, Christenson J, Spoelstra N, Elias A, Eisner J, Baskin-Bey E, Gertz J, Richer J. Abstract P5-05-05: Targeting the androgen receptor with seviteronel, a CYP17 lyase and AR inhibitor, in triple negative breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P5-05-05  0.327
2018 Mollaoglu G, Jones A, Wait SJ, Mukhopadhyay A, Jeong S, Arya R, Camolotto SA, Mosbruger TL, Stubben CJ, Conley CJ, Bhutkar A, Vahrenkamp JM, Berrett KC, Cessna MH, Lane TE, ... ... Gertz J, et al. The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment. Immunity. 49: 764-779.e9. PMID 30332632 DOI: 10.1016/J.Immuni.2018.09.020  0.342
2018 Carleton JB, Berrett KC, Gertz J. Dissection of Enhancer Function Using Multiplex CRISPR-based Enhancer Interference in Cell Lines. Journal of Visualized Experiments : Jove. PMID 29912188 DOI: 10.3791/57883  0.443
2018 Vahrenkamp JM, Yang CH, Rodriguez AC, Almomen A, Berrett KC, Trujillo AN, Guillen KP, Welm BE, Jarboe EA, Janat-Amsbury MM, Gertz J. Clinical and Genomic Crosstalk between Glucocorticoid Receptor and Estrogen Receptor α In Endometrial Cancer. Cell Reports. 22: 2995-3005. PMID 29539426 DOI: 10.1016/J.Celrep.2018.02.076  0.378
2018 Mollaoglu G, Guthrie MR, Bohm S, Bragelmann J, Chalishazar MD, Ireland AS, Huang F, Hu Z, Cardnell RJ, Sen T, Gertz J, Johnson JE, Gazdar AF, Byers LA, DeBerardinis RJ, et al. Abstract IA27: MYC drives molecular and therapeutically distinct subtype of SCLC Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-Ia27  0.341
2017 Carleton JB, Berrett KC, Gertz J. Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor α-Bound Enhancers. Cell Systems. PMID 28964699 DOI: 10.1016/J.Cels.2017.08.011  0.469
2017 Yang C, Gaffney DK, Werner TL, Jarboe EA, Gertz J, Varley KE, Peterson M, Janat-Amsbury MM. Abstract 1756: Genomic reclassification of endometrial carcinoma predicts drug response and facilitates refinement of current management based on PDX-guided efficacy outcomes Cancer Research. 77: 1756-1756. DOI: 10.1158/1538-7445.Am2017-1756  0.301
2016 Mollaoglu G, Guthrie MR, Böhm S, Brägelmann J, Can I, Ballieu PM, Marx A, George J, Heinen C, Chalishazar MD, Cheng H, Ireland AS, Denning KE, Mukhopadhyay A, Vahrenkamp JM, ... ... Gertz J, et al. MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition. Cancer Cell. PMID 28089889 DOI: 10.1016/J.Ccell.2016.12.005  0.339
2016 McDaniel JM, Varley KE, Gertz J, Savic DS, Roberts BS, Bailey SK, Shevde LA, Ramaker RC, Lasseigne BN, Kirby MK, Newberry KM, Partridge EC, Jones AL, Boone B, Levy SE, et al. Genomic regulation of invasion by STAT3 in triple negative breast cancer. Oncotarget. PMID 28030809 DOI: 10.18632/Oncotarget.14153  0.359
2016 D'Amato NC, Gordon MA, Babbs B, Spoelstra NS, Carson Butterfield KT, Torkko KC, Phan VT, Barton VN, Rogers TJ, Sartorius CA, Elias A, Gertz J, Jacobsen BM, Richer JK. Cooperative Dynamics of AR and ER Activity in Breast Cancer. Molecular Cancer Research : McR. PMID 27565181 DOI: 10.1158/1541-7786.Mcr-16-0167  0.323
2016 Savic D, Ramaker RC, Roberts BS, Dean EC, Burwell TC, Meadows SK, Cooper SJ, Garabedian MJ, Gertz J, Myers RM. Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation. Genome Medicine. 8: 74. PMID 27401066 DOI: 10.1186/S13073-016-0328-6  0.347
2016 Camp NJ, Lin WY, Bigelow A, Burghel GJ, Mosbruger T, Parry M, Waller RG, Rigas SH, Tai PY, Berrett K, Rajamanickam V, Cosby R, Brock IW, Jones B, Connley D, ... ... Gertz J, et al. Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus. Cancer Research. PMID 26795348 DOI: 10.1158/0008-5472.Can-15-1629  0.366
2016 Yang C, Jarboe EA, Gertz J, Varley KE, Peterson CM, Janát-Amsbury MM. Abstract 648: Integrated genomic characterization of endometrial cancer tumor grafts: a step toward genomic-guided treatment Cancer Research. 76: 648-648. DOI: 10.1158/1538-7445.Am2016-648  0.308
2015 Savic D, Roberts BS, Carleton JB, Partridge EC, White MA, Cohen BA, Cooper GM, Gertz J, Myers RM. Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/enhancer-binding protein beta binding sites. Genome Research. PMID 26486725 DOI: 10.1101/Gr.191593.115  0.627
2015 Slattery ML, Herrick JS, Mullany LE, Gertz J, Wolff RK. Improved survival among colon cancer patients with increased differentially expressed pathways. Bmc Medicine. 13: 75. PMID 25890236 DOI: 10.1186/S12916-015-0292-9  0.346
2014 Varley KE, Gertz J, Roberts BS, Davis NS, Bowling KM, Kirby MK, Nesmith AS, Oliver PG, Grizzle WE, Forero A, Buchsbaum DJ, LoBuglio AF, Myers RM. Recurrent read-through fusion transcripts in breast cancer. Breast Cancer Research and Treatment. 146: 287-97. PMID 24929677 DOI: 10.1007/S10549-014-3019-2  0.335
2014 Marinov GK, Williams BA, McCue K, Schroth GP, Gertz J, Myers RM, Wold BJ. From single-cell to cell-pool transcriptomes: stochasticity in gene expression and RNA splicing. Genome Research. 24: 496-510. PMID 24299736 DOI: 10.1101/Gr.161034.113  0.377
2013 Savic D, Gertz J, Jain P, Cooper GM, Myers RM. Mapping genome-wide transcription factor binding sites in frozen tissues. Epigenetics & Chromatin. 6: 30. PMID 24279905 DOI: 10.1186/1756-8935-6-30  0.387
2013 Gertz J, Savic D, Varley KE, Partridge EC, Safi A, Jain P, Cooper GM, Reddy TE, Crawford GE, Myers RM. Distinct properties of cell-type-specific and shared transcription factor binding sites. Molecular Cell. 52: 25-36. PMID 24076218 DOI: 10.1016/J.Molcel.2013.08.037  0.416
2013 Tsumagari K, Baribault C, Terragni J, Varley KE, Gertz J, Pradhan S, Badoo M, Crain CM, Song L, Crawford GE, Myers RM, Lacey M, Ehrlich M. Early de novo DNA methylation and prolonged demethylation in the muscle lineage. Epigenetics : Official Journal of the Dna Methylation Society. 8: 317-32. PMID 23417056 DOI: 10.4161/Epi.23989  0.327
2013 Varley KE, Gertz J, Bowling KM, Parker SL, Reddy TE, Pauli-Behn F, Cross MK, Williams BA, Stamatoyannopoulos JA, Crawford GE, Absher DM, Wold BJ, Myers RM. Dynamic DNA methylation across diverse human cell lines and tissues. Genome Research. 23: 555-67. PMID 23325432 DOI: 10.1101/Gr.147942.112  0.36
2012 Guo Y, Monahan K, Wu H, Gertz J, Varley KE, Li W, Myers RM, Maniatis T, Wu Q. CTCF/cohesin-mediated DNA looping is required for protocadherin α promoter choice. Proceedings of the National Academy of Sciences of the United States of America. 109: 21081-6. PMID 23204437 DOI: 10.1073/Pnas.1219280110  0.393
2012 Gertz J, Reddy TE, Varley KE, Garabedian MJ, Myers RM. Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner. Genome Research. 22: 2153-62. PMID 23019147 DOI: 10.1101/Gr.135681.111  0.45
2012 Landt SG, Marinov GK, Kundaje A, Kheradpour P, Pauli F, Batzoglou S, Bernstein BE, Bickel P, Brown JB, Cayting P, Chen Y, DeSalvo G, Epstein C, Fisher-Aylor KI, Euskirchen G, ... ... Gertz J, et al. ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. Genome Research. 22: 1813-31. PMID 22955991 DOI: 10.1101/Gr.136184.111  0.333
2012 Wang H, Maurano MT, Qu H, Varley KE, Gertz J, Pauli F, Lee K, Canfield T, Weaver M, Sandstrom R, Thurman RE, Kaul R, Myers RM, Stamatoyannopoulos JA. Widespread plasticity in CTCF occupancy linked to DNA methylation. Genome Research. 22: 1680-8. PMID 22955980 DOI: 10.1101/Gr.136101.111  0.419
2012 Gerstein MB, Kundaje A, Hariharan M, Landt SG, Yan KK, Cheng C, Mu XJ, Khurana E, Rozowsky J, Alexander R, Min R, Alves P, Abyzov A, Addleman N, Bhardwaj N, ... ... Gertz J, et al. Architecture of the human regulatory network derived from ENCODE data. Nature. 489: 91-100. PMID 22955619 DOI: 10.1038/Nature11245  0.41
2012 Reddy TE, Gertz J, Crawford GE, Garabedian MJ, Myers RM. The hypersensitive glucocorticoid response specifically regulates period 1 and expression of circadian genes. Molecular and Cellular Biology. 32: 3756-67. PMID 22801371 DOI: 10.1128/Mcb.00062-12  0.463
2012 Reddy TE, Gertz J, Pauli F, Kucera KS, Varley KE, Newberry KM, Marinov GK, Mortazavi A, Williams BA, Song L, Crawford GE, Wold B, Willard HF, Myers RM. Effects of sequence variation on differential allelic transcription factor occupancy and gene expression. Genome Research. 22: 860-9. PMID 22300769 DOI: 10.1101/Gr.131201.111  0.478
2012 Simpson NE, Gertz J, Imberg K, Myers RM, Garabedian MJ. Research resource: enhanced genome-wide occupancy of estrogen receptor α by the cochaperone p23 in breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 26: 194-202. PMID 22074947 DOI: 10.1210/Me.2011-1068  0.369
2011 Gertz J, Varley KE, Reddy TE, Bowling KM, Pauli F, Parker SL, Kucera KS, Willard HF, Myers RM. Analysis of DNA methylation in a three-generation family reveals widespread genetic influence on epigenetic regulation. Plos Genetics. 7: e1002228. PMID 21852959 DOI: 10.1371/Journal.Pgen.1002228  0.345
2011 Kucera KS, Reddy TE, Pauli F, Gertz J, Logan JE, Myers RM, Willard HF. Allele-specific distribution of RNA polymerase II on female X chromosomes. Human Molecular Genetics. 20: 3964-73. PMID 21791549 DOI: 10.1093/Hmg/Ddr315  0.378
2010 Gertz J, Gerke JP, Cohen BA. Epistasis in a quantitative trait captured by a molecular model of transcription factor interactions. Theoretical Population Biology. 77: 1-5. PMID 19818800 DOI: 10.1016/J.Tpb.2009.10.002  0.687
2009 Gertz J, Cohen BA. Environment-specific combinatorial cis-regulation in synthetic promoters. Molecular Systems Biology. 5: 244. PMID 19225457 DOI: 10.1038/Msb.2009.1  0.645
2009 Gertz J, Siggia ED, Cohen BA. Analysis of combinatorial cis-regulation in synthetic and genomic promoters. Nature. 457: 215-8. PMID 19029883 DOI: 10.1038/Nature07521  0.662
2007 Zeigler RD, Gertz J, Cohen BA. A cis-regulatory logic simulator. Bmc Bioinformatics. 8: 272. PMID 17662143 DOI: 10.1186/1471-2105-8-272  0.655
2006 Gertz J, Fay JC, Cohen BA. Phylogeny based discovery of regulatory elements. Bmc Bioinformatics. 7: 266. PMID 16716228 DOI: 10.1186/1471-2105-7-266  0.621
2005 Gertz J, Riles L, Turnbaugh P, Ho SW, Cohen BA. Discovery, validation, and genetic dissection of transcription factor binding sites by comparative and functional genomics. Genome Research. 15: 1145-52. PMID 16077013 DOI: 10.1101/Gr.3859605  0.644
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