Hung Ton-That, Ph.D. - Publications

Affiliations: 
2000 University of California, Los Angeles, Los Angeles, CA 
Area:
Microbiology

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Manne K, Chattopadhyay D, Agarwal V, Blom AM, Khare B, Chakravarthy S, Chang C, Ton-That H, Narayana SVL. Novel structure of the N-terminal helical domain of BibA, a group B streptococcus immunogenic bacterial adhesin. Acta Crystallographica. Section D, Structural Biology. 76: 759-770. PMID 32744258 DOI: 10.1107/S2059798320008116  0.32
2020 Gosschalk JE, Chang C, Sue CK, Siegel SD, Wu C, Kattke MD, Yi SW, Damoiseaux R, Jung ME, Ton-That H, Clubb RT. A Cell-based Screen in Actinomyces oris to Identify Sortase Inhibitors. Scientific Reports. 10: 8520. PMID 32444661 DOI: 10.1038/s41598-020-65256-x  0.44
2019 Chang C, Wu C, Osipiuk J, Siegel SD, Zhu S, Liu X, Joachimiak A, Clubb RT, Das A, Ton-That H. Cell-to-cell interaction requires optimal positioning of a pilus tip adhesin modulated by gram-positive transpeptidase enzymes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31427528 DOI: 10.1073/pnas.1907733116  0.44
2019 Siegel SD, Amer BR, Wu C, Sawaya MR, Gosschalk JE, Clubb RT, Ton-That H. Erratum for Siegel et al., "Structure and Mechanism of LcpA, a Phosphotransferase That Mediates Glycosylation of a Gram-Positive Bacterial Cell Wall-Anchored Protein". Mbio. 10. PMID 30992357 DOI: 10.1128/mBio.00617-19  0.44
2019 Siegel SD, Amer BR, Wu C, Sawaya MR, Gosschalk JE, Clubb RT, Ton-That H. Structure and Mechanism of LcpA, a Phosphotransferase That Mediates Glycosylation of a Gram-Positive Bacterial Cell Wall-Anchored Protein. Mbio. 10. PMID 30782654 DOI: 10.1128/mBio.01580-18  0.44
2018 McConnell SA, Amer BR, Muroski J, Fu J, Chang C, Loo RRO, Loo J, Osipiuk J, Ton-That H, Clubb RT. Protein Labeling via a Specific Lysine-Isopeptide Bond using the Pilin Polymerizing Sortase from Corynebacterium diphtheriae. Journal of the American Chemical Society. PMID 29927249 DOI: 10.1021/jacs.8b05200  0.44
2018 Chang C, Amer BR, Osipiuk J, McConnell SA, Huang IH, Hsieh V, Fu J, Nguyen HH, Muroski J, Flores E, Ogorzalek Loo RR, Loo JA, Putkey JA, Joachimiak A, Das A, ... ... Ton-That H, et al. In vitro reconstitution of sortase-catalyzed pilus polymerization reveals structural elements involved in pilin cross-linking. Proceedings of the National Academy of Sciences of the United States of America. PMID 29844180 DOI: 10.1073/pnas.1800954115  0.44
2018 Wittchen M, Busche T, Gaspar AH, Lee JH, Ton-That H, Kalinowski J, Tauch A. Transcriptome sequencing of the human pathogen Corynebacterium diphtheriae NCTC 13129 provides detailed insights into its transcriptional landscape and into DtxR-mediated transcriptional regulation. Bmc Genomics. 19: 82. PMID 29370758 DOI: 10.1186/s12864-018-4481-8  0.6
2016 Siegel SD, Liu J, Ton-That H. Biogenesis of the Gram-positive bacterial cell envelope. Current Opinion in Microbiology. 34: 31-37. PMID 27497053 DOI: 10.1016/j.mib.2016.07.015  1
2016 Siegel SD, Wu C, Ton-That H. A type I signal peptidase is required for pilus assembly in the Gram-positive biofilm-forming bacterium Actinomyces oris. Journal of Bacteriology. PMID 27215787 DOI: 10.1128/JB.00353-16  1
2016 Montealegre MC, Singh KV, Somarajan SR, Yadav P, Chang C, Spencer R, Sillanpää J, Ton-That H, Murray BE. Role of the Emp Pilus Subunits of Enterococcus faecium in Biofilm Formation, Adherence to Host Extracellular Matrix Components and Experimental Infection. Infection and Immunity. PMID 26930703 DOI: 10.1128/IAI.01396-15  1
2016 Echelman DJ, Alegre-Cebollada J, Badilla CL, Chang C, Ton-That H, Fernández JM. CnaA domains in bacterial pili are efficient dissipaters of large mechanical shocks. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884173 DOI: 10.1073/pnas.1522946113  1
2015 Reardon-Robinson ME, Osipiuk J, Jooya N, Chang C, Joachimiak A, Das A, Ton-That H. A thiol-disulfide oxidoreductase of the Gram-positive pathogen Corynebacterium diphtheriae is essential for viability, pilus assembly, toxin production and virulence. Molecular Microbiology. PMID 26294390 DOI: 10.1111/mmi.13172  1
2015 Reardon-Robinson ME, Osipiuk J, Chang C, Wu C, Jooya N, Joachimiak A, Das A, Ton-That H. A Disulfide Bond-Forming Machine is Linked to the Sortase-Mediated Pilus Assembly Pathway in the Gram-Positive Bacterium Actinomyces Oris. The Journal of Biological Chemistry. PMID 26170452 DOI: 10.1074/jbc.M115.672253  1
2015 Galloway-Peña JR, Liang X, Singh KV, Yadav P, Chang C, La Rosa SL, Shelburne S, Ton-That H, Höök M, Murray BE. The identification and functional characterization of WxL proteins from Enterococcus faecium reveal surface proteins involved in extracellular matrix interactions. Journal of Bacteriology. 197: 882-92. PMID 25512313 DOI: 10.1128/JB.02288-14  1
2014 Wu C, Huang IH, Chang C, Reardon-Robinson ME, Das A, Ton-That H. Lethality of sortase depletion in Actinomyces oris caused by excessive membrane accumulation of a surface glycoprotein. Molecular Microbiology. 94: 1227-41. PMID 25230351 DOI: 10.1111/mmi.12780  1
2014 Kang HJ, Paterson NG, Kim CU, Middleditch M, Chang C, Ton-That H, Baker EN. A slow-forming isopeptide bond in the structure of the major pilin SpaD from Corynebacterium diphtheriae has implications for pilus assembly. Acta Crystallographica. Section D, Biological Crystallography. 70: 1190-201. PMID 24816089 DOI: 10.1107/S1399004714001400  1
2014 Reardon-Robinson ME, Wu C, Mishra A, Chang C, Bier N, Das A, Ton-That H. Pilus hijacking by a bacterial coaggregation factor critical for oral biofilm development. Proceedings of the National Academy of Sciences of the United States of America. 111: 3835-40. PMID 24567409 DOI: 10.1073/pnas.1321417111  1
2014 Reardon-Robinson ME, Ton-That H. Assembly and function of corynebacterium diphtheriae pili Corynebacterium Diphtheriae and Related Toxigenic Species: Genomics, Pathogenicity and Applications. 2147483647: 123-141. DOI: 10.1007/978-94-007-7624-1_7  1
2013 Sillanpää J, Chang C, Singh KV, Montealegre MC, Nallapareddy SR, Harvey BR, Ton-That H, Murray BE. Contribution of individual Ebp Pilus subunits of Enterococcus faecalis OG1RF to pilus biogenesis, biofilm formation and urinary tract infection. Plos One. 8: e68813. PMID 23874774 DOI: 10.1371/journal.pone.0068813  1
2013 Broadway MM, Rogers EA, Chang C, Huang IH, Dwivedi P, Yildirim S, Schmitt MP, Das A, Ton-That H. Pilus gene pool variation and the virulence of Corynebacterium diphtheriae clinical isolates during infection of a nematode. Journal of Bacteriology. 195: 3774-83. PMID 23772071 DOI: 10.1128/JB.00500-13  1
2013 Krishnan V, Dwivedi P, Kim BJ, Samal A, Macon K, Ma X, Mishra A, Doran KS, Ton-That H, Narayana SV. Structure of Streptococcus agalactiae tip pilin GBS104: a model for GBS pili assembly and host interactions. Acta Crystallographica. Section D, Biological Crystallography. 69: 1073-89. PMID 23695252 DOI: 10.1107/S0907444913004642  1
2013 Chang C, Huang IH, Hendrickx AP, Ton-That H. Visualization of Gram-positive bacterial pili. Methods in Molecular Biology (Clifton, N.J.). 966: 77-95. PMID 23299729 DOI: 10.1007/978-1-62703-245-2_5  1
2012 Trost E, Blom J, Soares Sde C, Huang IH, Al-Dilaimi A, Schröder J, Jaenicke S, Dorella FA, Rocha FS, Miyoshi A, Azevedo V, Schneider MP, Silva A, Camello TC, Sabbadini PS, ... ... Ton-That H, et al. Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia. Journal of Bacteriology. 194: 3199-215. PMID 22505676 DOI: 10.1128/JB.00183-12  1
2012 Wu C, Mishra A, Reardon ME, Huang IH, Counts SC, Das A, Ton-That H. Structural determinants of Actinomyces sortase SrtC2 required for membrane localization and assembly of type 2 fimbriae for interbacterial coaggregation and oral biofilm formation. Journal of Bacteriology. 194: 2531-9. PMID 22447896 DOI: 10.1128/JB.00093-12  1
2011 Khare B, Krishnan V, Rajashankar KR, I-Hsiu H, Xin M, Ton-That H, Narayana SV. Structural differences between the Streptococcus agalactiae housekeeping and pilus-specific sortases: SrtA and SrtC1. Plos One. 6: e22995. PMID 21912586 DOI: 10.1371/journal.pone.0022995  1
2011 Mishra A, Devarajan B, Reardon ME, Dwivedi P, Krishnan V, Cisar JO, Das A, Narayana SV, Ton-That H. Two autonomous structural modules in the fimbrial shaft adhesin FimA mediate Actinomyces interactions with streptococci and host cells during oral biofilm development. Molecular Microbiology. 81: 1205-20. PMID 21696465 DOI: 10.1111/j.1365-2958.2011.07745.x  1
2011 Rogers EA, Das A, Ton-That H. Adhesion by pathogenic corynebacteria. Advances in Experimental Medicine and Biology. 715: 91-103. PMID 21557059 DOI: 10.1007/978-94-007-0940-9_6  1
2011 Wu C, Mishra A, Yang J, Cisar JO, Das A, Ton-That H. Dual function of a tip fimbrillin of Actinomyces in fimbrial assembly and receptor binding. Journal of Bacteriology. 193: 3197-206. PMID 21531799 DOI: 10.1128/JB.00173-11  1
2011 Vengadesan K, Ma X, Dwivedi P, Ton-That H, Narayana SV. A model for group B Streptococcus pilus type 1: the structure of a 35-kDa C-terminal fragment of the major pilin GBS80. Journal of Molecular Biology. 407: 731-43. PMID 21333654 DOI: 10.1016/j.jmb.2011.02.024  1
2011 Chang C, Mandlik A, Das A, Ton-That H. Cell surface display of minor pilin adhesins in the form of a simple heterodimeric assembly in Corynebacterium diphtheriae. Molecular Microbiology. 79: 1236-47. PMID 21205008 DOI: 10.1111/j.1365-2958.2010.07515.x  1
2010 Vengadesan K, Ma X, Dwivedi P, Ton-That H, Narayana SV. Purification, crystallization and halide phasing of a Streptococcus agalactiae backbone pilin GBS80 fragment. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1666-9. PMID 21139220 DOI: 10.1107/S1744309110043101  1
2010 Khare B, Samal A, Vengadesan K, Rajashankar KR, Ma X, Huang IH, Ton-That H, Narayana SV. Preliminary crystallographic study of the Streptococcus agalactiae sortases, sortase A and sortase C1. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1096-100. PMID 20823536 DOI: 10.1107/S1744309110031106  1
2010 Sillanpää J, Nallapareddy SR, Singh KV, Prakash VP, Fothergill T, Ton-That H, Murray BE. Characterization of the ebp(fm) pilus-encoding operon of Enterococcus faecium and its role in biofilm formation and virulence in a murine model of urinary tract infection. Virulence. 1: 236-46. PMID 20676385  1
2010 Wu C, Ton-That H. Allelic exchange in Actinomyces oris with mCherry fluorescence counterselection. Applied and Environmental Microbiology. 76: 5987-9. PMID 20601506 DOI: 10.1128/AEM.00811-10  1
2010 Mishra A, Wu C, Yang J, Cisar JO, Das A, Ton-That H. The Actinomyces oris type 2 fimbrial shaft FimA mediates co-aggregation with oral streptococci, adherence to red blood cells and biofilm development. Molecular Microbiology. 77: 841-54. PMID 20545853 DOI: 10.1111/j.1365-2958.2010.07252.x  1
2009 Kang HJ, Paterson NG, Gaspar AH, Ton-That H, Baker EN. The Corynebacterium diphtheriae shaft pilin SpaA is built of tandem Ig-like modules with stabilizing isopeptide and disulfide bonds. Proceedings of the National Academy of Sciences of the United States of America. 106: 16967-71. PMID 19805181 DOI: 10.1073/pnas.0906826106  0.6
2009 Guttilla IK, Gaspar AH, Swierczynski A, Swaminathan A, Dwivedi P, Das A, Ton-That H. Acyl enzyme intermediates in sortase-catalyzed pilus morphogenesis in gram-positive bacteria. Journal of Bacteriology. 191: 5603-12. PMID 19592583 DOI: 10.1128/JB.00627-09  1
2009 Hae JK, Paterson NG, Gaspar AH, Ton-That H, Baker EN. The Corynebacterium diphtheriae shaft pilin SpaA is built of tandem Ig-like modules with stabilizing isopeptide and disulfide bonds (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 40, (16967-16971) 10.1073/pnas.090682610) Proceedings of the National Academy of Sciences of the United States of America. 106: 18427. DOI: 10.1073/pnas.0911293106  1
2008 Mandlik A, Das A, Ton-That H. The molecular switch that activates the cell wall anchoring step of pilus assembly in gram-positive bacteria. Proceedings of the National Academy of Sciences of the United States of America. 105: 14147-52. PMID 18779588 DOI: 10.1073/pnas.0806350105  1
2008 Mandlik A, Swierczynski A, Das A, Ton-That H. Pili in Gram-positive bacteria: assembly, involvement in colonization and biofilm development. Trends in Microbiology. 16: 33-40. PMID 18083568 DOI: 10.1016/j.tim.2007.10.010  1
2007 Swaminathan A, Mandlik A, Swierczynski A, Gaspar A, Das A, Ton-That H. Housekeeping sortase facilitates the cell wall anchoring of pilus polymers in Corynebacterium diphtheriae. Molecular Microbiology. 66: 961-74. PMID 17919283 DOI: 10.1111/j.1365-2958.2007.05968.x  1
2007 Krishnan V, Gaspar AH, Ye N, Mandlik A, Ton-That H, Narayana SV. An IgG-like domain in the minor pilin GBS52 of Streptococcus agalactiae mediates lung epithelial cell adhesion. Structure (London, England : 1993). 15: 893-903. PMID 17697995 DOI: 10.1016/j.str.2007.06.015  1
2007 Mandlik A, Swierczynski A, Das A, Ton-That H. Corynebacterium diphtheriae employs specific minor pilins to target human pharyngeal epithelial cells. Molecular Microbiology. 64: 111-24. PMID 17376076 DOI: 10.1111/j.1365-2958.2007.05630.x  1
2007 Mishra A, Das A, Cisar JO, Ton-That H. Sortase-catalyzed assembly of distinct heteromeric fimbriae in Actinomyces naeslundii. Journal of Bacteriology. 189: 3156-65. PMID 17277070 DOI: 10.1128/JB.01952-06  1
2006 Swierczynski A, Ton-That H. Type III pilus of corynebacteria: Pilus length is determined by the level of its major pilin subunit. Journal of Bacteriology. 188: 6318-25. PMID 16923899 DOI: 10.1128/JB.00606-06  1
2006 Gaspar AH, Ton-That H. Assembly of distinct pilus structures on the surface of Corynebacterium diphtheriae. Journal of Bacteriology. 188: 1526-33. PMID 16452436 DOI: 10.1128/JB.188.4.1526-1533.2006  1
2005 Gaspar AH, Marraffini LA, Glass EM, Debord KL, Ton-That H, Schneewind O. Bacillus anthracis sortase A (SrtA) anchors LPXTG motif-containing surface proteins to the cell wall envelope. Journal of Bacteriology. 187: 4646-55. PMID 15968076 DOI: 10.1128/JB.187.13.4646-4655.2005  1
2004 Ton-That H, Marraffini LA, Schneewind O. Protein sorting to the cell wall envelope of Gram-positive bacteria. Biochimica Et Biophysica Acta. 1694: 269-78. PMID 15546671 DOI: 10.1016/j.bbamcr.2004.04.014  1
2004 Goss JW, Sorg JA, Ramamurthi KS, Ton-That H, Schneewind O. The secretion signal of YopN, a regulatory protein of the Yersinia enterocolitica type III secretion pathway. Journal of Bacteriology. 186: 6320-4. PMID 15342604 DOI: 10.1128/JB.186.18.6320-6324.2004  1
2004 Marraffini LA, Ton-That H, Zong Y, Narayana SV, Schneewind O. Anchoring of surface proteins to the cell wall of Staphylococcus aureus. A conserved arginine residue is required for efficient catalysis of sortase A. The Journal of Biological Chemistry. 279: 37763-70. PMID 15247224 DOI: 10.1074/jbc.M405282200  1
2004 Ton-That H, Marraffini LA, Schneewind O. Sortases and pilin elements involved in pilus assembly of Corynebacterium diphtheriae. Molecular Microbiology. 53: 251-61. PMID 15225319 DOI: 10.1111/j.1365-2958.2004.04117.x  1
2004 Ton-That H, Schneewind O. Assembly of pili in Gram-positive bacteria. Trends in Microbiology. 12: 228-34. PMID 15120142 DOI: 10.1016/j.tim.2004.03.004  1
2004 Zong Y, Bice TW, Ton-That H, Schneewind O, Narayana SV. Crystal structures of Staphylococcus aureus sortase A and its substrate complex. The Journal of Biological Chemistry. 279: 31383-9. PMID 15117963 DOI: 10.1074/jbc.M401374200  1
2003 Ton-That H, Schneewind O. Assembly of pili on the surface of Corynebacterium diphtheriae. Molecular Microbiology. 50: 1429-38. PMID 14622427 DOI: 10.1046/j.1365-2958.2003.03782.x  1
2002 Perry AM, Ton-That H, Mazmanian SK, Schneewind O. Anchoring of surface proteins to the cell wall of Staphylococcus aureus. III. Lipid II is an in vivo peptidoglycan substrate for sortase-catalyzed surface protein anchoring. The Journal of Biological Chemistry. 277: 16241-8. PMID 11856734 DOI: 10.1074/jbc.M109194200  1
2002 Mazmanian SK, Ton-That H, Su K, Schneewind O. An iron-regulated sortase anchors a class of surface protein during Staphylococcus aureus pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 99: 2293-8. PMID 11830639 DOI: 10.1073/pnas.032523999  1
2002 Ton-That H, Mazmanian SK, Alksne L, Schneewind O. Anchoring of surface proteins to the cell wall of Staphylococcus aureus. Cysteine 184 and histidine 120 of sortase form a thiolate-imidazolium ion pair for catalysis. The Journal of Biological Chemistry. 277: 7447-52. PMID 11714722 DOI: 10.1074/jbc.M109945200  1
2001 Mazmanian SK, Ton-That H, Schneewind O. Sortase-catalysed anchoring of surface proteins to the cell wall of Staphylococcus aureus. Molecular Microbiology. 40: 1049-57. PMID 11401711 DOI: 10.1046/j.1365-2958.2001.02411.x  1
2001 Ilangovan U, Ton-That H, Iwahara J, Schneewind O, Clubb RT. Structure of sortase, the transpeptidase that anchors proteins to the cell wall of Staphylococcus aureus. Proceedings of the National Academy of Sciences of the United States of America. 98: 6056-61. PMID 11371637 DOI: 10.1073/pnas.101064198  1
2001 Ilangovan U, Iwahara J, Ton-That H, Schneewind O, Clubb RT. Assignment of the 1H, 13C and 15N signals of Sortase. Journal of Biomolecular Nmr. 19: 379-80. PMID 11370786 DOI: 10.1023/A:1011299500628  1
2001 Ton-That H, Mazmanian SK, Schneewind O. An embarrassment of sortases - A richness of substrates? Response Trends in Microbiology. 9: 101-102. DOI: 10.1016/S0966-842X(01)01955-2  1
2000 Ton-That H, Mazmanian SK, Faull KF, Schneewind O. Anchoring of surface proteins to the cell wall of Staphylococcus aureus. Sortase catalyzed in vitro transpeptidation reaction using LPXTG peptide and NH(2)-Gly(3) substrates. The Journal of Biological Chemistry. 275: 9876-81. PMID 10734144 DOI: 10.1074/jbc.275.13.9876  1
1999 Ton-That H, Liu G, Mazmanian SK, Faull KF, Schneewind O. Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif. Proceedings of the National Academy of Sciences of the United States of America. 96: 12424-9. PMID 10535938 DOI: 10.1073/pnas.96.22.12424  1
1999 Ton-That H, Schneewind O. Anchor structure of staphylococcal surface proteins. IV. Inhibitors of the cell wall sorting reaction. The Journal of Biological Chemistry. 274: 24316-20. PMID 10446208 DOI: 10.1074/jbc.274.34.24316  1
1999 Mazmanian SK, Liu G, Ton-That H, Schneewind O. Staphylococcus aureus sortase, an enzyme that anchors surface proteins to the cell wall. Science (New York, N.Y.). 285: 760-3. PMID 10427003 DOI: 10.1126/science.285.5428.760  1
1999 Navarre WW, Ton-That H, Faull KF, Schneewind O. Multiple enzymatic activities of the murein hydrolase from staphylococcal phage phi11. Identification of a D-alanyl-glycine endopeptidase activity. The Journal of Biological Chemistry. 274: 15847-56. PMID 10336488 DOI: 10.1074/jbc.274.22.15847  1
1998 Ton-That H, Labischinski H, Berger-Bächi B, Schneewind O. Anchor structure of staphylococcal surface proteins. III. Role of the FemA, FemB, and FemX factors in anchoring surface proteins to the bacterial cell wall. The Journal of Biological Chemistry. 273: 29143-9. PMID 9786923 DOI: 10.1074/jbc.273.44.29143  1
1998 Navarre WW, Ton-That H, Faull KF, Schneewind O. Anchor structure of staphylococcal surface proteins. II. Cooh-terminal structure of muramidase and amidase-solubilized surface protein. The Journal of Biological Chemistry. 273: 29135-42. PMID 9786922 DOI: 10.1074/jbc.273.44.29135  1
1998 Fournier G, Potier J, Thébaud HE, Majdalani G, Ton-That H, Man NK. Substitution of acetic acid for hydrochloric acid in the bicarbonate buffered dialysate Artificial Organs. 22: 608-613. PMID 9684700 DOI: 10.1046/j.1525-1594.1998.06205.x  1
1997 Ton-That H, Faull KF, Schneewind O. Anchor structure of staphylococcal surface proteins. A branched peptide that links the carboxyl terminus of proteins to the cell wall. The Journal of Biological Chemistry. 272: 22285-92. PMID 9268378 DOI: 10.1074/jbc.272.35.22285  1
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