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Eain A. Murphy, Ph.D. - Publications

Affiliations: 
2000 University of Iowa, Iowa City, IA 
Area:
Molecular Biology, Microbiology
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Szemere ZK, Murphy EA. Herpes Simplex Virus-1 targets the 2'-3'cGAMP importer SLC19A1 as an antiviral countermeasure. Biorxiv : the Preprint Server For Biology. PMID 38328222 DOI: 10.1101/2024.01.24.577105  0.384
2023 Poole E, Lau J, Groves I, Roche K, Murphy E, Carlan da Silva M, Reeves M, Sinclair J. The Human Cytomegalovirus Latency-Associated Gene Product Latency Unique Natural Antigen Regulates Latent Gene Expression. Viruses. 15. PMID 37766281 DOI: 10.3390/v15091875  0.4
2022 Krishna BA, Wass AB, Murphy EA, O'Connor CM. Design of a US28 ORF Deletion Virus in a Temperature-Sensitive Cytomegalovirus Strain Fails to Promote Lytic Replication in Hematopoietic Cells. Viruses. 14. PMID 35746751 DOI: 10.3390/v14061280  0.388
2022 Perera MR, Roche KL, Murphy EA, Sinclair JH. A Viral Long Non-Coding RNA Protects against Cell Death during Human Cytomegalovirus Infection of CD14+ Monocytes. Viruses. 14. PMID 35215840 DOI: 10.3390/v14020246  0.313
2020 Nukui M, Roche KL, Jia J, Fox PL, Murphy EA. Protein S-nitrosylation of Human Cytomegalovirus pp71 inhibits its ability to limit STING antiviral responses. Journal of Virology. PMID 32581105 DOI: 10.1128/JVI.00033-20  0.377
2019 Poole E, Huang CJZ, Forbester J, Shnayder M, Nachshon A, Kweider B, Basaj A, Smith D, Jackson SE, Liu B, Shih J, Kiskin FN, Roche K, Murphy E, Wills MR, et al. An iPSC-Derived Myeloid Lineage Model of Herpes Virus Latency and Reactivation. Frontiers in Microbiology. 10: 2233. PMID 31649625 DOI: 10.3389/Fmicb.2019.02233  0.457
2019 Kim ET, Roche KL, Kulej K, Spruce LA, Seeholzer SH, Coen DM, Diaz-Griffero F, Murphy EA, Weitzman MD. SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-κB Activation. Cell Reports. 28: 434-448.e6. PMID 31291579 DOI: 10.1016/J.Celrep.2019.06.027  0.453
2019 Elder E, Krishna B, Williamson J, Aslam Y, Farahi N, Wood A, Romashova V, Roche K, Murphy E, Chilvers E, Lehner PJ, Sinclair J, Poole E. Monocytes Latently Infected with Human Cytomegalovirus Evade Neutrophil Killing. Iscience. 12: 13-26. PMID 30677738 DOI: 10.1016/J.Isci.2019.01.007  0.469
2018 Nukui M, O'Connor CM, Murphy EA. The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts. Viruses. 10. PMID 30405048 DOI: 10.3390/V10110614  0.436
2018 Roche KL, Nukui M, Krishna BA, O'Connor CM, Murphy EA. Selective 4-thiouracil labeling of RNA transcripts within latently infected cells after infection with human cytomegalovirus expressing functional uracil phosphoribosyltransferase. Journal of Virology. PMID 30089702 DOI: 10.1128/Jvi.00880-18  0.513
2018 Procter DJ, Banerjee A, Nukui M, Kruse K, Gaponenko V, Murphy EA, Komarova Y, Walsh D. The HCMV Assembly Compartment Is a Dynamic Golgi-Derived MTOC that Controls Nuclear Rotation and Virus Spread. Developmental Cell. 45: 83-100.e7. PMID 29634939 DOI: 10.1016/J.Devcel.2018.03.010  0.375
2016 Lau B, Poole E, Krishna B, Sellart I, Wills MR, Murphy E, Sinclair J. The Expression of Human Cytomegalovirus MicroRNA MiR-UL148D during Latent Infection in Primary Myeloid Cells Inhibits Activin A-triggered Secretion of IL-6. Scientific Reports. 6: 31205. PMID 27491954 DOI: 10.1038/Srep31205  0.447
2016 Lau B, Poole E, Van Damme E, Bunkens L, Sowash M, King H, Murphy E, Wills M, Van Loock M, Sinclair J. Human cytomegalovirus miR-UL112-1 promotes the down-regulation of viral immediate early gene expression during latency to prevent T cell recognition of latently infected cells. The Journal of General Virology. PMID 27411311 DOI: 10.1099/Jgv.0.000546  0.458
2016 O'Connor CM, Nukui M, Gurova KV, Murphy EA. Inhibition of the Facilitates Chromatin Transcription (FACT) complex reduces transcription from the HCMV MIEP in models of lytic and latent replication. Journal of Virology. PMID 26865717 DOI: 10.1128/Jvi.02501-15  0.415
2015 Nukui M, Mori Y, Murphy EA. A human herpesvirus 6A-encoded microRNA: role in viral lytic replication. Journal of Virology. 89: 2615-27. PMID 25520507 DOI: 10.1128/Jvi.02007-14  0.372
2014 Moorman NJ, Murphy EA. Roseomics: a blank slate. Current Opinion in Virology. 9: 188-93. PMID 25437230 DOI: 10.1016/J.Coviro.2014.09.021  0.33
2014 O'Connor CM, Vanicek J, Murphy EA. Host microRNA regulation of human cytomegalovirus immediate early protein translation promotes viral latency. Journal of Virology. 88: 5524-32. PMID 24599990 DOI: 10.1128/Jvi.00481-14  0.429
2013 Schuster AT, Sarvepalli K, Murphy EA, Longworth MS. Condensin II subunit dCAP-D3 restricts retrotransposon mobilization in Drosophila somatic cells. Plos Genetics. 9: e1003879. PMID 24204294 DOI: 10.1371/Journal.Pgen.1003879  0.317
2013 Tanner A, Carlson SA, Nukui M, Murphy EA, Berges BK. Human herpesvirus 6A infection and immunopathogenesis in humanized Rag2⁻/⁻ γc⁻/⁻ mice. Journal of Virology. 87: 12020-8. PMID 24006442 DOI: 10.1128/Jvi.01556-13  0.374
2012 O'Connor CM, Murphy EA. A myeloid progenitor cell line capable of supporting human cytomegalovirus latency and reactivation, resulting in infectious progeny. Journal of Virology. 86: 9854-65. PMID 22761372 DOI: 10.1128/Jvi.01278-12  0.535
2012 Lee SH, Kalejta RF, Kerry J, Semmes OJ, O'Connor CM, Khan Z, Garcia BA, Shenk T, Murphy E. BclAF1 restriction factor is neutralized by proteasomal degradation and microRNA repression during human cytomegalovirus infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 9575-80. PMID 22645331 DOI: 10.1073/Pnas.1207496109  0.519
2008 Murphy E, Vanícek J, Robins H, Shenk T, Levine AJ. Suppression of immediate-early viral gene expression by herpesvirus-coded microRNAs: implications for latency. Proceedings of the National Academy of Sciences of the United States of America. 105: 5453-8. PMID 18378902 DOI: 10.1073/Pnas.0711910105  0.351
2007 Wang D, Yu QC, Schröer J, Murphy E, Shenk T. Human cytomegalovirus uses two distinct pathways to enter retinal pigmented epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 20037-42. PMID 18077432 DOI: 10.1073/Pnas.0709704104  0.395
2000 Murphy EA, Streblow DN, Nelson JA, Stinski MF. The human cytomegalovirus IE86 protein can block cell cycle progression after inducing transition into the S phase of permissive cells. Journal of Virology. 74: 7108-18. PMID 10888651 DOI: 10.1128/Jvi.74.15.7108-7118.2000  0.602
1998 Lashmit PE, Stinski MF, Murphy EA, Bullock GC. A cis repression sequence adjacent to the transcription start site of the human cytomegalovirus US3 gene is required to down regulate gene expression at early and late times after infection. Journal of Virology. 72: 9575-84. PMID 9811691 DOI: 10.1128/Jvi.72.12.9575-9584.1998  0.561
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