Shane Crotty, Ph.D. - Publications

Affiliations: 
2001 University of California, San Francisco, San Francisco, CA 
Area:
Cell Biology, Microbiology

180 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Coelho CH, Bloom N, Ramirez SI, Parikh UM, Heaps A, Sieg SF, Greninger A, Ritz J, Moser C, Eron JJ, Currier JS, Klekotka P, Wohl DA, Daar ES, Li J, ... ... Crotty S, et al. SARS-CoV-2 monoclonal antibody treatment followed by vaccination shifts human memory B cell epitope recognition suggesting antibody feedback. Biorxiv : the Preprint Server For Biology. PMID 38045374 DOI: 10.1101/2023.11.21.567575  0.305
2023 Ramirez SI, Lopez PG, Faraji F, Parikh UM, Heaps A, Ritz J, Moser C, Eron JJ, Wohl DA, Currier JS, Daar ES, Greninger AL, Klekotka P, Grifoni A, Weiskopf D, ... ... Crotty S, et al. Early antiviral CD4 and CD8 T cell responses are associated with upper respiratory tract clearance of SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 37961119 DOI: 10.1101/2023.10.25.564014  0.361
2023 Phung I, Rodrigues KA, Marina-Zárate E, Maiorino L, Pahar B, Lee WH, Melo M, Kaur A, Allers C, Fahlberg M, Grasperge BF, Dufour JP, Schiro F, Aye PP, Lopez PG, ... ... Crotty S, et al. A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates. Nature Communications. 14: 7107. PMID 37925510 DOI: 10.1038/s41467-023-42923-x  0.33
2023 Getzler AJ, Frederick MA, Milner JJ, Venables T, Diao H, Toma C, Nagaraja SD, Albao DS, Bélanger S, Tsuda SM, Kim J, Crotty S, Goldrath AW, Pipkin ME. Mll1 pioneers histone H3K4me3 deposition and promotes formation of CD8 T stem cell memory. Biorxiv : the Preprint Server For Biology. PMID 37090503 DOI: 10.1101/2023.01.18.524461  0.305
2023 Kim YJ, Oh J, Jung S, Kim CJ, Choi J, Jeon YK, Kim HJ, Kim JW, Suh CH, Lee Y, Im SH, Crotty S, Choi YS. The transcription factor Mef2d regulates B:T synapse-dependent GC-T differentiation and IL-21-mediated humoral immunity. Science Immunology. 8: eadf2248. PMID 36961907 DOI: 10.1126/sciimmunol.adf2248  0.32
2022 Sette A, Sidney J, Crotty S. T Cell Responses to SARS-CoV-2. Annual Review of Immunology. PMID 36750314 DOI: 10.1146/annurev-immunol-101721-061120  0.373
2022 Ramirez SI, Grifoni A, Weiskopf D, Parikh UM, Heaps A, Faraji F, Sieg SF, Ritz J, Moser CB, Eron JJ, Currier JS, Klekotka P, Sette A, Wohl DA, Daar ES, ... ... Crotty S, et al. Bamlanivimab therapy for acute COVID-19 does not blunt SARS-CoV-2-specific memory T cell responses. Jci Insight. PMID 36378539 DOI: 10.1172/jci.insight.163471  0.331
2022 Lee JH, Sutton HJ, Cottrell CA, Phung I, Ozorowski G, Sewall LM, Nedellec R, Nakao C, Silva M, Richey ST, Torre JL, Lee WH, Georgeson E, Kubitz M, Hodges S, ... ... Crotty S, et al. Long-primed germinal centres with enduring affinity maturation and clonal migration. Nature. PMID 36131022 DOI: 10.1038/s41586-022-05216-9  0.325
2022 Bélanger S, Haupt S, Freeman BL, Getzler AJ, Diao H, Pipkin ME, Crotty S. The Transcription Factor YY-1 Is an Essential Regulator of T Follicular Helper Cell Differentiation. Journal of Immunology (Baltimore, Md. : 1950). PMID 36096645 DOI: 10.4049/jimmunol.2101176  0.313
2022 He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, ... ... Crotty S, et al. Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques. Science Translational Medicine. 14: eabl9605. PMID 35947674 DOI: 10.1126/scitranslmed.abl9605  0.304
2022 Rydyznski Moderbacher C, Kim CJ, Mateus J, Plested JS, Zhu M, Cloney-Clark S, Weiskopf D, Sette A, Fries L, Glenn G, Crotty S. NVX-CoV2373 vaccination induces functional SARS-CoV-2-specific CD4+ and CD8+ T cell responses. The Journal of Clinical Investigation. PMID 35943810 DOI: 10.1172/JCI160898  0.352
2022 Zhang Z, Mateus J, Coelho CH, Dan JM, Moderbacher CR, Gálvez RI, Cortes FH, Grifoni A, Tarke A, Chang J, Escarrega EA, Kim C, Goodwin B, Bloom NI, Frazier A, ... ... Crotty S, et al. Humoral and cellular immune memory to four COVID-19 vaccines. Cell. PMID 35764089 DOI: 10.1016/j.cell.2022.05.022  0.338
2022 Sette A, Crotty S. Immunological memory to SARS-CoV-2 infection and COVID-19 vaccines. Immunological Reviews. PMID 35733376 DOI: 10.1111/imr.13089  0.309
2022 Dan J, da Silva Antunes R, Grifoni A, Weiskopf D, Crotty S, Sette A. Observations and perspectives on adaptive immunity to SARS-CoV-2. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 35441229 DOI: 10.1093/cid/ciac310  0.363
2022 Zhang Z, Mateus J, Coelho CH, Dan JM, Moderbacher CR, Gálvez RI, Cortes FH, Grifoni A, Tarke A, Chang J, Escarrega EA, Kim C, Goodwin B, Bloom NI, Frazier A, ... ... Crotty S, et al. Humoral and cellular immune memory to four COVID-19 vaccines. Biorxiv : the Preprint Server For Biology. PMID 35350195 DOI: 10.1101/2022.03.18.484953  0.35
2022 Yu ED, Wang E, Garrigan E, Goodwin B, Sutherland A, Tarke A, Chang J, Gálvez RI, Mateus J, Ramirez SI, Rawlings SA, Smith DM, Filaci G, Frazier A, Weiskopf D, ... ... Crotty S, et al. Development of a T cell-based immunodiagnostic system to effectively distinguish SARS-CoV-2 infection and COVID-19 vaccination status. Cell Host & Microbe. PMID 35172129 DOI: 10.1016/j.chom.2022.02.003  0.308
2022 Tarke A, Coelho CH, Zhang Z, Dan JM, Yu ED, Methot N, Bloom NI, Goodwin B, Phillips E, Mallal S, Sidney J, Filaci G, Weiskopf D, da Silva Antunes R, Crotty S, et al. SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron. Cell. PMID 35139340 DOI: 10.1016/j.cell.2022.01.015  0.348
2021 van Schooten J, van Haaren MM, Li H, McCoy LE, Havenar-Daughton C, Cottrell CA, Burger JA, van der Woude P, Helgers LC, Tomris I, Labranche CC, Montefiori DC, Ward AB, Burton DR, Moore JP, ... ... Crotty S, et al. Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates. Plos Pathogens. 17: e1009736. PMID 34432859 DOI: 10.1371/journal.ppat.1009736  0.313
2021 Grifoni A, Sidney J, Vita R, Peters B, Crotty S, Weiskopf D, Sette A. SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19. Cell Host & Microbe. 29: 1076-1092. PMID 34237248 DOI: 10.1016/j.chom.2021.05.010  0.349
2021 Tarke A, Sidney J, Methot N, Yu ED, Zhang Y, Dan JM, Goodwin B, Rubiro P, Sutherland A, Wang E, Frazier A, Ramirez SI, Rawlings SA, Smith DM, da Silva Antunes R, ... ... Crotty S, et al. Impact of SARS-CoV-2 variants on the total CD4 and CD8 T cell reactivity in infected or vaccinated individuals. Cell Reports. Medicine. 100355. PMID 34230917 DOI: 10.1016/j.xcrm.2021.100355  0.306
2021 Milner JJ, Toma C, Quon S, Omilusik K, Scharping NE, Dey A, Reina-Campos M, Nguyen H, Getzler AJ, Diao H, Yu B, Delpoux A, Yoshida TM, Li D, Qi J, ... ... Crotty S, et al. Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection. The Journal of Experimental Medicine. 218. PMID 34037670 DOI: 10.1084/jem.20202512  0.323
2021 Sette A, Crotty S. Adaptive immunity to SARS-CoV-2 and COVID-19. Cell. 184: 861-880. PMID 33497610 DOI: 10.1016/j.cell.2021.01.007  0.371
2021 Lee JH, Hu JK, Georgeson E, Nakao C, Groschel B, Dileepan T, Jenkins MK, Seumois G, Vijayanand P, Schief WR, Crotty S. Modulating the quantity of HIV Env-specific CD4 T cell help promotes rare B cell responses in germinal centers. The Journal of Experimental Medicine. 218. PMID 33355623 DOI: 10.1084/jem.20201254  0.391
2020 Rydyznski Moderbacher C, Ramirez SI, Dan JM, Grifoni A, Hastie KM, Weiskopf D, Belanger S, Abbott RK, Kim C, Choi J, Kato Y, Crotty EG, Kim C, Rawlings SA, Mateus J, ... ... Crotty S, et al. Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity. Cell. PMID 33010815 DOI: 10.1016/J.Cell.2020.09.038  0.415
2020 Huang D, Abbott RK, Havenar-Daughton C, Skog PD, Al-Kolla R, Groschel B, Blane TR, Menis S, Tran JT, Thinnes TC, Volpi SA, Liguori A, Schiffner T, Villegas SM, Kalyuzhniy O, ... ... Crotty S, et al. B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models. Proceedings of the National Academy of Sciences of the United States of America. PMID 32873644 DOI: 10.1073/Pnas.2004489117  0.405
2020 Kato Y, Abbott RK, Freeman BL, Haupt S, Groschel B, Silva M, Menis S, Irvine DJ, Schief WR, Crotty S. Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo. Immunity. PMID 32857950 DOI: 10.1016/J.Immuni.2020.08.001  0.442
2020 Mateus J, Grifoni A, Tarke A, Sidney J, Ramirez SI, Dan JM, Burger ZC, Rawlings SA, Smith DM, Phillips E, Mallal S, Lammers M, Rubiro P, Quiambao L, Sutherland A, ... ... Crotty S, et al. Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans. Science (New York, N.Y.). PMID 32753554 DOI: 10.1126/Science.Abd3871  0.438
2020 Sette A, Crotty S. Pre-existing immunity to SARS-CoV-2: the knowns and unknowns. Nature Reviews. Immunology. PMID 32636479 DOI: 10.1038/S41577-020-0389-Z  0.445
2020 Carnathan DG, Kaushik K, Ellebedy AH, Enemuo CA, Gebru EH, Dhadvai P, Rasheed MAU, Pauthner MG, Ozorowski G, Ahmed R, Burton DR, Ward AB, Silvestri G, Crotty S, Locci M. Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers. Frontiers in Immunology. 11: 1213. PMID 32612608 DOI: 10.3389/Fimmu.2020.01213  0.458
2020 Choi J, Diao H, Faliti CE, Truong J, Rossi M, Bélanger S, Yu B, Goldrath AW, Pipkin ME, Crotty S. Bcl-6 is the nexus transcription factor of T follicular helper cells via repressor-of-repressor circuits. Nature Immunology. PMID 32572238 DOI: 10.1038/S41590-020-0706-5  0.402
2020 Kasturi SP, Rasheed MAU, Havenar-Daughton C, Pham M, Legere T, Sher ZJ, Kovalenkov Y, Gumber S, Huang JY, Gottardo R, Fulp W, Sato A, Sawant S, Stanfield-Oakley S, Yates N, ... ... Crotty S, et al. 3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope-specific plasma cells and humoral immunity in nonhuman primates. Science Immunology. 5. PMID 32561559 DOI: 10.1126/Sciimmunol.Abb1025  0.419
2020 Abbott RK, Crotty S. Factors in B cell competition and immunodominance. Immunological Reviews. PMID 32483855 DOI: 10.1111/Imr.12861  0.437
2020 Grifoni A, Weiskopf D, Ramirez SI, Mateus J, Dan JM, Moderbacher CR, Rawlings SA, Sutherland A, Premkumar L, Jadi RS, Marrama D, de Silva AM, Frazier A, Carlin AF, Greenbaum JA, ... ... Crotty S, et al. Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals. Cell. PMID 32473127 DOI: 10.1016/J.Cell.2020.05.015  0.432
2020 Moyer TJ, Kato Y, Abraham W, Chang JYH, Kulp DW, Watson N, Turner HL, Menis S, Abbott RK, Bhiman JN, Melo MB, Simon HA, Herrera-De la Mata S, Liang S, Seumois G, ... ... Crotty S, et al. Engineered immunogen binding to alum adjuvant enhances humoral immunity. Nature Medicine. PMID 32066977 DOI: 10.1038/S41591-020-0753-3  0.428
2020 Havenar-Daughton C, Newton IG, Zare SY, Reiss SM, Schwan B, Suh MJ, Hasteh F, Levi G, Crotty S. Normal human lymph node T follicular helper cells and germinal center B cells accessed via fine needle aspirations. Journal of Immunological Methods. 112746. PMID 31958451 DOI: 10.1016/J.Jim.2020.112746  0.355
2019 Havenar-Daughton C, Carnathan DG, Boopathy AV, Upadhyay AA, Murrell B, Reiss SM, Enemuo CA, Gebru EH, Choe Y, Dhadvai P, Viviano F, Kaushik K, Bhiman JN, Briney B, Burton DR, ... ... Crotty S, et al. Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization. Cell Reports. 29: 1756-1766.e8. PMID 31722194 DOI: 10.1016/J.Celrep.2019.10.008  0.402
2019 Steichen JM, Lin YC, Havenar-Daughton C, Pecetta S, Ozorowski G, Willis JR, Toy L, Sok D, Liguori A, Kratochvil S, Torres JL, Kalyuzhniy O, Melzi E, Kulp DW, Raemisch S, ... ... Crotty S, et al. A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science (New York, N.Y.). PMID 31672916 DOI: 10.1126/Science.Aax4380  0.403
2019 Crotty S. Editorial overview: Vaccine immunology: what is seen and not seen. Current Opinion in Immunology. PMID 31235312 DOI: 10.1016/J.Coi.2019.05.010  0.316
2019 Crotty S. T Follicular Helper Cell Biology: A Decade of Discovery and Diseases. Immunity. 50: 1132-1148. PMID 31117010 DOI: 10.1016/J.Immuni.2019.04.011  0.457
2019 Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, ... ... Crotty S, et al. Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance. Cell. PMID 31080066 DOI: 10.1016/J.Cell.2019.04.012  0.432
2019 Dan JM, Havenar-Daughton C, Kendric K, Al-Kolla R, Kaushik K, Rosales SL, Anderson EL, LaRock CN, Vijayanand P, Seumois G, Layfield D, Cutress RI, Ottensmeier CH, Lindestam Arlehamn CS, Sette A, ... ... Crotty S, et al. Recurrent group A tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant T cells. Science Translational Medicine. 11. PMID 30728285 DOI: 10.1126/Scitranslmed.Aau3776  0.387
2018 Li F, Zeng Z, Xing S, Gullicksrud JA, Shan Q, Choi J, Badovinac VP, Crotty S, Peng W, Xue HH. Ezh2 programs T differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf. Nature Communications. 9: 5452. PMID 30575739 DOI: 10.1038/S41467-018-07853-Z  0.365
2018 Pauthner MG, Nkolola JP, Havenar-Daughton C, Murrell B, Reiss SM, Bastidas R, Prévost J, Nedellec R, von Bredow B, Abbink P, Cottrell CA, Kulp DW, Tokatlian T, Nogal B, Bianchi M, ... ... Crotty S, et al. Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers. Immunity. PMID 30552025 DOI: 10.1016/J.Immuni.2018.11.011  0.433
2018 Havenar-Daughton C, Abbott RK, Schief WR, Crotty S. When designing vaccines, consider the starting material: the human B cell repertoire. Current Opinion in Immunology. 53: 209-216. PMID 30190230 DOI: 10.1016/J.Coi.2018.08.002  0.454
2018 Patricia D'Souza M, Allen MA, Baumblatt JAG, Boggiano C, Crotty S, Grady C, Havenar-Daughton C, Heit A, Hu DJ, Kunwar N, McElrath MJ. Innovative approaches to track lymph node germinal center responses to evaluate development of broadly neutralizing antibodies in human HIV vaccine trials. Vaccine. PMID 30097219 DOI: 10.1016/J.Vaccine.2018.07.071  0.335
2018 Cho S, Lee HM, Yu IS, Choi YS, Huang HY, Hashemifar SS, Lin LL, Chen MC, Afanasiev ND, Khan AA, Lin SW, Rudensky AY, Crotty S, Lu LF. Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b. Nature Communications. 9: 2757. PMID 30013024 DOI: 10.1038/S41467-018-05196-3  0.306
2018 Havenar-Daughton C, Sarkar A, Kulp DW, Toy L, Hu X, Deresa I, Kalyuzhniy O, Kaushik K, Upadhyay AA, Menis S, Landais E, Cao L, Diedrich JK, Kumar S, Schiffner T, ... ... Crotty S, et al. The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen. Science Translational Medicine. 10. PMID 29973404 DOI: 10.1126/Scitranslmed.Aat0381  0.432
2018 da Silva Antunes R, Babor M, Carpenter C, Khalil N, Cortese M, Mentzer AJ, Seumois G, Petro CD, Purcell LA, Vijayanand P, Crotty S, Pulendran B, Peters B, Sette A. Th1/Th17 polarization persists following whole-cell pertussis vaccination despite repeated acellular boosters. The Journal of Clinical Investigation. PMID 29920186 DOI: 10.1172/Jci121309  0.392
2018 Wang D, Diao H, Getzler AJ, Rogal W, Frederick MA, Milner J, Yu B, Crotty S, Goldrath AW, Pipkin ME. The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation. Immunity. 48: 659-674.e6. PMID 29669249 DOI: 10.1016/J.Immuni.2018.03.028  0.346
2018 Upadhyay AA, Kauffman RC, Wolabaugh AN, Cho A, Patel NB, Reiss SM, Havenar-Daughton C, Dawoud RA, Tharp GK, Sanz I, Pulendran B, Crotty S, Lee FE, Wrammert J, Bosinger SE. BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data. Genome Medicine. 10: 20. PMID 29558968 DOI: 10.1186/S13073-018-0528-3  0.464
2018 Meng X, Kaever T, Yan B, Traktman P, Zajonc DM, Peters B, Crotty S, Xiang Y. Characterization of murine antibody responses to vaccinia virus envelope protein A14 reveals an immunodominant antigen lacking of effective neutralization targets. Virology. 518: 284-292. PMID 29558682 DOI: 10.1016/J.Virol.2018.03.005  0.399
2018 Gaddis DE, Padgett LE, Wu R, McSkimming C, Romines V, Taylor AM, McNamara CA, Kronenberg M, Crotty S, Thomas MJ, Sorci-Thomas MG, Hedrick CC. Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis. Nature Communications. 9: 1095. PMID 29545616 DOI: 10.1038/S41467-018-03493-5  0.404
2018 Klasse PJ, Ketas TJ, Cottrell CA, Ozorowski G, Debnath G, Camara D, Francomano E, Pugach P, Ringe RP, LaBranche CC, van Gils MJ, Bricault CA, Barouch DH, Crotty S, Silvestri G, et al. Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques. Plos Pathogens. 14: e1006913. PMID 29474444 DOI: 10.1371/Journal.Ppat.1006913  0.366
2018 Milner JJ, Toma C, Yu B, Zhang K, Omilusik K, Phan AT, Wang D, Getzler AJ, Nguyen T, Crotty S, Wang W, Pipkin ME, Goldrath AW. Erratum: Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours. Nature. PMID 29320476 DOI: 10.1038/Nature25445  0.323
2018 Crotty S. Raging evolution of a b cell response to a viral infection. Nature Reviews. Immunology. PMID 29292394 DOI: 10.1038/Nri.2017.219  0.376
2017 Abbott RK, Lee JH, Menis S, Skog P, Rossi M, Ota T, Kulp DW, Bhullar D, Kalyuzhniy O, Havenar-Daughton C, Schief WR, Nemazee D, Crotty S. Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens. Immunity. PMID 29287996 DOI: 10.1016/J.Immuni.2017.11.023  0.402
2017 Milner JJ, Toma C, Yu B, Zhang K, Omilusik K, Phan AT, Wang D, Getzler AJ, Nguyen T, Crotty S, Wang W, Pipkin ME, Goldrath AW. Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours. Nature. 552: 253-257. PMID 29211713 DOI: 10.1038/Nature24993  0.423
2017 Kulp DW, Steichen JM, Pauthner M, Hu X, Schiffner T, Liguori A, Cottrell CA, Havenar-Daughton C, Ozorowski G, Georgeson E, Kalyuzhniy O, Willis JR, Kubitz M, Adachi Y, Reiss SM, ... ... Crotty S, et al. Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding. Nature Communications. 8: 1655. PMID 29162799 DOI: 10.1038/S41467-017-01549-6  0.386
2017 Reiss S, Baxter AE, Cirelli KM, Dan JM, Morou A, Daigneault A, Brassard N, Silvestri G, Routy JP, Havenar-Daughton C, Crotty S, Kaufmann DE. Comparative analysis of activation induced marker (AIM) assays for sensitive identification of antigen-specific CD4 T cells. Plos One. 12: e0186998. PMID 29065175 DOI: 10.1371/Journal.Pone.0186998  0.419
2017 Cirelli KM, Crotty S. Germinal center enhancement by extended antigen availability. Current Opinion in Immunology. 47: 64-69. PMID 28738289 DOI: 10.1016/J.Coi.2017.06.008  0.448
2017 Wing JB, Kitagawa Y, Locci M, Hume H, Tay C, Morita T, Kidani Y, Matsuda K, Inoue T, Kurosaki T, Crotty S, Coban C, Ohkura N, Sakaguchi S. A distinct subpopulation of CD25(-) T-follicular regulatory cells localizes in the germinal centers. Proceedings of the National Academy of Sciences of the United States of America. PMID 28698369 DOI: 10.1073/Pnas.1705551114  0.401
2017 Pauthner M, Havenar-Daughton C, Sok D, Nkolola JP, Bastidas R, Boopathy AV, Carnathan DG, Chandrashekar A, Cirelli KM, Cottrell CA, Eroshkin AM, Guenaga J, Kaushik K, Kulp DW, Liu J, ... ... Crotty S, et al. Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches. Immunity. 46: 1073-1088.e6. PMID 28636956 DOI: 10.1016/J.Immuni.2017.05.007  0.387
2017 Schulten V, Tripple V, Seumois G, Qian Y, Scheuermann RH, Fu Z, Locci M, Rosales S, Vijayanand P, Sette A, Alam R, Crotty S, Peters B. Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells. The Journal of Allergy and Clinical Immunology. PMID 28506846 DOI: 10.1016/J.Jaci.2017.04.032  0.426
2017 Zaitseva M, Thomas A, Meseda CA, Cheung CYK, Diaz CG, Xiang Y, Crotty S, Golding H. Development of an animal model of progressive vaccinia in nu/nu mice and the use of bioluminescence imaging for assessment of the efficacy of monoclonal antibodies against vaccinial B5 and L1 proteins. Antiviral Research. PMID 28495463 DOI: 10.1016/J.Antiviral.2017.05.002  0.385
2017 Crotty S. Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment? Complexities of Interpretation due to the Heterogeneity of Memory CD4 T Cells, Including T Follicular Helper Cells. Cold Spring Harbor Perspectives in Biology. PMID 28432129 DOI: 10.1101/Cshperspect.A032102  0.398
2017 Yu B, Zhang K, Milner JJ, Toma C, Chen R, Scott-Browne JP, Pereira RM, Crotty S, Chang JT, Pipkin ME, Wang W, Goldrath AW. Epigenetic landscapes reveal transcription factors that regulate CD8(+) T cell differentiation. Nature Immunology. PMID 28288100 DOI: 10.1038/Ni.3706  0.384
2017 Polonskaya Z, Deng S, Sarkar A, Kain L, Comellas-Aragones M, McKay CS, Kaczanowska K, Holt M, McBride R, Palomo V, Self KM, Taylor S, Irimia A, Mehta SR, Dan JM, ... ... Crotty S, et al. T cells control the generation of nanomolar-affinity anti-glycan antibodies. The Journal of Clinical Investigation. PMID 28287405 DOI: 10.1172/Jci91192  0.494
2017 Havenar-Daughton C, Lee JH, Crotty S. Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem. Immunological Reviews. 275: 49-61. PMID 28133798 DOI: 10.1111/Imr.12512  0.387
2017 da Silva Antunes R, Paul S, Sidney J, Weiskopf D, Dan JM, Phillips E, Mallal S, Crotty S, Sette A, Lindestam Arlehamn CS. Definition of Human Epitopes Recognized in Tetanus Toxoid and Development of an Assay Strategy to Detect Ex Vivo Tetanus CD4+ T Cell Responses. Plos One. 12: e0169086. PMID 28081174 DOI: 10.1371/Journal.Pone.0169086  0.454
2016 Kasturi SP, Kozlowski PA, Nakaya HI, Burger MC, Russo P, Pham M, Kovalenkov Y, Silveira EL, Havenar-Daughton C, Burton SL, Kilgore KM, Johnson MJ, Nabi R, Legere T, Sher ZJ, ... ... Crotty S, et al. Adjuvanting an SIV vaccine with TLR ligands encapsulated in nanoparticles induces persistent antibody responses and enhanced protection in TRIM5α restrictive macaques. Journal of Virology. PMID 27928002 DOI: 10.1128/Jvi.01844-16  0.394
2016 Havenar-Daughton C, Carnathan DG, Torrents de la Peña A, Pauthner M, Briney B, Reiss SM, Wood JS, Kaushik K, van Gils MJ, Rosales SL, van der Woude P, Locci M, Le KM, de Taeye SW, Sok D, ... ... Crotty S, et al. Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer. Cell Reports. 17: 2195-2209. PMID 27880897 DOI: 10.1016/J.Celrep.2016.10.085  0.396
2016 Tam HH, Melo MB, Kang M, Pelet JM, Ruda VM, Foley MH, Hu JK, Kumari S, Crampton J, Baldeon AD, Sanders RW, Moore JP, Crotty S, Langer R, Anderson DG, et al. Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination. Proceedings of the National Academy of Sciences of the United States of America. PMID 27702895 DOI: 10.1073/Pnas.1606050113  0.408
2016 Dan JM, Havenar-Daughton C, Silvestri G, Sette A, Crotty S. Response to Comment on "A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood". Journal of Immunology (Baltimore, Md. : 1950). 197: 2558. PMID 27638936 DOI: 10.4049/jimmunol.1601321  0.322
2016 Locci M, Wu JE, Arumemi F, Mikulski Z, Dahlberg C, Miller AT, Crotty S. Activin A programs the differentiation of human TFH cells. Nature Immunology. PMID 27376469 DOI: 10.1038/Ni.3494  0.401
2016 Dan JM, Lindestam Arlehamn CS, Weiskopf D, da Silva Antunes R, Havenar-Daughton C, Reiss SM, Brigger M, Bothwell M, Sette A, Crotty S. A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood. Journal of Immunology (Baltimore, Md. : 1950). PMID 27342848 DOI: 10.4049/Jimmunol.1600318  0.439
2016 Havenar-Daughton C, Reiss SM, Carnathan DG, Wu JE, Kendric K, Torrents de la Peña A, Kasturi SP, Dan JM, Bothwell M, Sanders RW, Pulendran B, Silvestri G, Crotty S. Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique. Journal of Immunology (Baltimore, Md. : 1950). PMID 27335502 DOI: 10.4049/Jimmunol.1600320  0.473
2016 Hu JK, Crampton JC, Locci M, Crotty S. CRISPR-Mediated Slamf1Δ/Δ Slamf5Δ/Δ Slamf6Δ/Δ Triple Gene Disruption Reveals NKT Cell Defects but Not T Follicular Helper Cell Defects. Plos One. 11: e0156074. PMID 27223891 DOI: 10.1371/Journal.Pone.0156074  0.437
2016 Shaw LA, Bélanger S, Omilusik KD, Cho S, Scott-Browne JP, Nance JP, Goulding J, Lasorella A, Lu LF, Crotty S, Goldrath AW. Id2 reinforces TH1 differentiation and inhibits E2A to repress TFH differentiation. Nature Immunology. PMID 27213691 DOI: 10.1038/Ni.3461  0.42
2016 Bancroft T, Dillon MB, da Silva Antunes R, Paul S, Peters B, Crotty S, Lindestam Arlehamn CS, Sette A. Th1 versus Th2 T cell polarization by whole-cell and acellular childhood pertussis vaccines persists upon re-immunization in adolescence and adulthood. Cellular Immunology. PMID 27212461 DOI: 10.1016/J.Cellimm.2016.05.002  0.429
2016 Pedros C, Zhang Y, Hu JK, Choi YS, Canonigo-Balancio AJ, Yates JR, Altman A, Crotty S, Kong KF. A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1. Nature Immunology. PMID 27135603 DOI: 10.1038/Ni.3463  0.383
2016 Jardine JG, Kulp DW, Havenar-Daughton C, Sarkar A, Briney B, Sok D, Sesterhenn F, Ereño-Orbea J, Kalyuzhniy O, Deresa I, Hu X, Spencer S, Jones M, Georgeson E, Adachi Y, ... ... Crotty S, et al. HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen. Science (New York, N.Y.). 351: 1458-63. PMID 27013733 DOI: 10.1126/Science.Aad9195  0.398
2016 Havenar-Daughton C, Lindqvist M, Heit A, Wu JE, Reiss SM, Kendric K, Bélanger S, Kasturi SP, Landais E, Akondy RS, McGuire HM, Bothwell M, Vagefi PA, Scully E, ... ... Crotty S, et al. CXCL13 is a plasma biomarker of germinal center activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 26908875 DOI: 10.1073/Pnas.1520112113  0.419
2016 Kaever T, Matho MH, Meng X, Crickard L, Schlossman A, Xiang Y, Crotty S, Peters B, Zajonc DM. Linear epitopes in A27 are targets of protective antibodies induced by vaccination against smallpox. Journal of Virology. PMID 26889021 DOI: 10.1128/Jvi.02878-15  0.338
2016 Martinez GJ, Hu JK, Pereira RM, Crampton JS, Togher S, Bild N, Crotty S, Rao A. Cutting Edge: NFAT Transcription Factors Promote the Generation of Follicular Helper T Cells in Response to Acute Viral Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 26851216 DOI: 10.4049/Jimmunol.1501841  0.438
2016 Landais E, Huang X, Havenar-Daughton C, Murrell B, Price MA, Wickramasinghe L, Ramos A, Bian CB, Simek M, Allen S, Karita E, Kilembe W, Lakhi S, Inambao M, Kamali A, ... ... Crotty S, et al. Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort. Plos Pathogens. 12: e1005369. PMID 26766578 DOI: 10.1371/Journal.Ppat.1005369  0.424
2015 de Taeye SW, Ozorowski G, Torrents de la Peña A, Guttman M, Julien JP, van den Kerkhof TL, Burger JA, Pritchard LK, Pugach P, Yasmeen A, Crampton J, Hu J, Bontjer I, Torres JL, Arendt H, ... ... Crotty S, et al. Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes. Cell. 163: 1702-15. PMID 26687358 DOI: 10.1016/J.Cell.2015.11.056  0.352
2015 Cubas R, van Grevenynghe J, Wills S, Kardava L, Santich BH, Buckner CM, Muir R, Tardif V, Nichols C, Procopio F, He Z, Metcalf T, Ghneim K, Locci M, Ancuta P, ... ... Crotty S, et al. Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 26546609 DOI: 10.4049/Jimmunol.1501524  0.415
2015 Matho MH, Schlossman A, Meng X, Benhnia MR, Kaever T, Buller M, Doronin K, Parker S, Peters B, Crotty S, Xiang Y, Zajonc DM. Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer. Plos Pathogens. 11: e1005148. PMID 26325270 DOI: 10.1371/Journal.Ppat.1005148  0.313
2015 Hu JK, Crampton JC, Cupo A, Ketas T, van Gils MJ, Sliepen K, de Taeye SW, Sok D, Ozorowski G, Deresa I, Stanfield R, Ward AB, Burton DR, Klasse PJ, Sanders RW, ... ... Crotty S, et al. Murine antibody responses to cleaved soluble HIV-1 envelope trimers are highly restricted in specificity. Journal of Virology. PMID 26246566 DOI: 10.1128/Jvi.01653-15  0.407
2015 Choi YS, Gullicksrud JA, Xing S, Zeng Z, Shan Q, Li F, Love PE, Peng W, Xue HH, Crotty S. LEF-1 and TCF-1 orchestrate TFH differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6. Nature Immunology. PMID 26214741 DOI: 10.1038/Ni.3226  0.399
2015 Weiskopf D, Bangs DJ, Sidney J, Kolla RV, De Silva AD, de Silva AM, Crotty S, Peters B, Sette A. Dengue virus infection elicits highly polarized CX3CR1+ cytotoxic CD4+ T cells associated with protective immunity. Proceedings of the National Academy of Sciences of the United States of America. 112: E4256-63. PMID 26195744 DOI: 10.1073/Pnas.1505956112  0.494
2015 Nance JP, Bélanger S, Johnston RJ, Takemori T, Crotty S. Cutting edge: T follicular helper cell differentiation is defective in the absence of Bcl6 BTB repressor domain function. Journal of Immunology (Baltimore, Md. : 1950). 194: 5599-603. PMID 25957170 DOI: 10.4049/Jimmunol.1500200  0.42
2015 Crotty S, Pipkin ME. In vivo RNAi screens: concepts and applications. Trends in Immunology. 36: 315-22. PMID 25937561 DOI: 10.1016/J.It.2015.03.007  0.375
2015 Choi YS, Crotty S. Retroviral vector expression in TCR transgenic CD4⁺ T cells. Methods in Molecular Biology (Clifton, N.J.). 1291: 49-61. PMID 25836301 DOI: 10.1007/978-1-4939-2498-1_5  0.334
2015 Hatzi K, Nance JP, Kroenke MA, Bothwell M, Haddad EK, Melnick A, Crotty S. BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms. The Journal of Experimental Medicine. 212: 539-53. PMID 25824819 DOI: 10.1084/Jem.20141380  0.387
2015 Martinez GJ, Pereira RM, Äijö T, Kim EY, Marangoni F, Pipkin ME, Togher S, Heissmeyer V, Zhang YC, Crotty S, Lamperti ED, Ansel KM, Mempel TR, Lähdesmäki H, Hogan PG, et al. The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells. Immunity. 42: 265-78. PMID 25680272 DOI: 10.1016/J.Immuni.2015.01.006  0.417
2015 Crotty S. A brief history of T cell help to B cells. Nature Reviews. Immunology. 15: 185-9. PMID 25677493 DOI: 10.1038/Nri3803  0.406
2014 Matho MH, de Val N, Miller GM, Brown J, Schlossman A, Meng X, Crotty S, Peters B, Xiang Y, Hsieh-Wilson LC, Ward AB, Zajonc DM. Murine anti-vaccinia virus D8 antibodies target different epitopes and differ in their ability to block D8 binding to CS-E. Plos Pathogens. 10: e1004495. PMID 25474621 DOI: 10.1371/Journal.Ppat.1004495  0.317
2014 Crotty S. T follicular helper cell differentiation, function, and roles in disease. Immunity. 41: 529-42. PMID 25367570 DOI: 10.1016/J.Immuni.2014.10.004  0.44
2014 Chen R, Bélanger S, Frederick MA, Li B, Johnston RJ, Xiao N, Liu YC, Sharma S, Peters B, Rao A, Crotty S, Pipkin ME. In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation. Immunity. 41: 325-38. PMID 25148027 DOI: 10.1016/J.Immuni.2014.08.002  0.441
2014 Kaever T, Meng X, Matho MH, Schlossman A, Li S, Sela-Culang I, Ofran Y, Buller M, Crump RW, Parker S, Frazier A, Crotty S, Zajonc DM, Peters B, Xiang Y. Potent neutralization of vaccinia virus by divergent murine antibodies targeting a common site of vulnerability in L1 protein. Journal of Virology. 88: 11339-55. PMID 25031354 DOI: 10.1128/Jvi.01491-14  0.381
2014 Hong JJ, Amancha PK, Rogers KA, Courtney CL, Havenar-Daughton C, Crotty S, Ansari AA, Villinger F. Early lymphoid responses and germinal center formation correlate with lower viral load set points and better prognosis of simian immunodeficiency virus infection. Journal of Immunology (Baltimore, Md. : 1950). 193: 797-806. PMID 24907346 DOI: 10.4049/Jimmunol.1400749  0.392
2014 Xiao N, Eto D, Elly C, Peng G, Crotty S, Liu YC. The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells. Nature Immunology. 15: 657-66. PMID 24859451 DOI: 10.1038/Ni.2912  0.417
2014 Wang H, Geng J, Wen X, Bi E, Kossenkov AV, Wolf AI, Tas J, Choi YS, Takata H, Day TJ, Chang LY, Sprout SL, Becker EK, Willen J, Tian L, ... ... Crotty S, et al. The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells. Nature Immunology. 15: 667-75. PMID 24859450 DOI: 10.1038/Ni.2890  0.427
2014 Sela-Culang I, Benhnia MR, Matho MH, Kaever T, Maybeno M, Schlossman A, Nimrod G, Li S, Xiang Y, Zajonc D, Crotty S, Ofran Y, Peters B. Using a combined computational-experimental approach to predict antibody-specific B cell epitopes. Structure (London, England : 1993). 22: 646-57. PMID 24631463 DOI: 10.1016/J.Str.2014.02.003  0.348
2014 Hatzi K, Nance JP, Kroenke M, Haddad EK, Melnick AM, Crotty S. BCL6 Orchestrates Tfh Differentiation Via Multiple Distinct Mechanisms Blood. 124: 4137-4137. DOI: 10.1182/Blood.V124.21.4137.4137  0.409
2014 Gilmour J, Kamali A, Karita E, Kilembe W, Sanders EJ, Anzala O, Allen S, Edward V, Priddy F, Price MA, Macharia G, Baalwa J, Crotty S, Denny T, Landais E, et al. African Early Infection Cohort as a Platform for Vaccine Discovery: The IAVI Protocol C Experience Aids Research and Human Retroviruses. 30. DOI: 10.1089/Aid.2014.5048.Abstract  0.317
2013 Boettler T, Choi YS, Salek-Ardakani S, Cheng Y, Moeckel F, Croft M, Crotty S, von Herrath M. Exogenous OX40 stimulation during lymphocytic choriomeningitis virus infection impairs follicular Th cell differentiation and diverts CD4 T cells into the effector lineage by upregulating Blimp-1. Journal of Immunology (Baltimore, Md. : 1950). 191: 5026-35. PMID 24101548 DOI: 10.4049/Jimmunol.1300013  0.466
2013 Locci M, Havenar-Daughton C, Landais E, Wu J, Kroenke MA, Arlehamn CL, Su LF, Cubas R, Davis MM, Sette A, Haddad EK, Poignard P, Crotty S. Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses. Immunity. 39: 758-69. PMID 24035365 DOI: 10.1016/J.Immuni.2013.08.031  0.407
2013 Hu J, Havenar-Daughton C, Crotty S. Modulation of SAP dependent T:B cell interactions as a strategy to improve vaccination. Current Opinion in Virology. 3: 363-70. PMID 23743125 DOI: 10.1016/J.Coviro.2013.05.015  0.469
2013 Choi YS, Yang JA, Crotty S. Dynamic regulation of Bcl6 in follicular helper CD4 T (Tfh) cells. Current Opinion in Immunology. 25: 366-72. PMID 23688737 DOI: 10.1016/J.Coi.2013.04.003  0.458
2013 Choi YS, Yang JA, Yusuf I, Johnston RJ, Greenbaum J, Peters B, Crotty S. Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memory. Journal of Immunology (Baltimore, Md. : 1950). 190: 4014-26. PMID 23487426 DOI: 10.4049/Jimmunol.1202963  0.418
2013 Cubas RA, Mudd JC, Savoye AL, Perreau M, van Grevenynghe J, Metcalf T, Connick E, Meditz A, Freeman GJ, Abesada-Terk G, Jacobson JM, Brooks AD, Crotty S, Estes JD, Pantaleo G, et al. Inadequate T follicular cell help impairs B cell immunity during HIV infection. Nature Medicine. 19: 494-9. PMID 23475201 DOI: 10.1038/Nm.3109  0.409
2013 Choi YS, Eto D, Yang JA, Lao C, Crotty S. Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 190: 3049-53. PMID 23447690 DOI: 10.4049/Jimmunol.1203032  0.32
2013 Streeck H, D'Souza MP, Littman DR, Crotty S. Harnessing CD4⁺ T cell responses in HIV vaccine development. Nature Medicine. 19: 143-9. PMID 23389614 DOI: 10.1038/Nm.3054  0.451
2013 Benhnia MR, Maybeno M, Blum D, Aguilar-Sino R, Matho M, Meng X, Head S, Felgner PL, Zajonc DM, Koriazova L, Kato S, Burton DR, Xiang Y, Crowe JE, Peters B, ... Crotty S, et al. Unusual features of vaccinia virus extracellular virion form neutralization resistance revealed in human antibody responses to the smallpox vaccine. Journal of Virology. 87: 1569-85. PMID 23152530 DOI: 10.1128/Jvi.02152-12  0.392
2013 Crotty S, Discovery V. S-4 Cytokine. 63: 241. DOI: 10.1016/J.Cyto.2013.06.305  0.443
2012 Crickard L, Babas T, Seth S, Silvera P, Koriazova L, Crotty S. Protection of rabbits and immunodeficient mice against lethal poxvirus infections by human monoclonal antibodies. Plos One. 7: e48706. PMID 23133652 DOI: 10.1371/Journal.Pone.0048706  0.37
2012 Burton DR, Ahmed R, Barouch DH, Butera ST, Crotty S, Godzik A, Kaufmann DE, McElrath MJ, Nussenzweig MC, Pulendran B, Scanlan CN, Schief WR, Silvestri G, Streeck H, Walker BD, et al. A Blueprint for HIV Vaccine Discovery. Cell Host & Microbe. 12: 396-407. PMID 23084910 DOI: 10.1016/J.Chom.2012.09.008  0.393
2012 Boettler T, Moeckel F, Cheng Y, Heeg M, Salek-Ardakani S, Crotty S, Croft M, von Herrath MG. OX40 facilitates control of a persistent virus infection. Plos Pathogens. 8: e1002913. PMID 22969431 DOI: 10.1371/Journal.Ppat.1002913  0.452
2012 Kageyama R, Cannons JL, Zhao F, Yusuf I, Lao C, Locci M, Schwartzberg PL, Crotty S. The receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development. Immunity. 36: 986-1002. PMID 22683125 DOI: 10.1016/J.Immuni.2012.05.016  0.43
2012 Matho MH, Maybeno M, Benhnia MR, Becker D, Meng X, Xiang Y, Crotty S, Peters B, Zajonc DM. Structural and biochemical characterization of the vaccinia virus envelope protein D8 and its recognition by the antibody LA5. Journal of Virology. 86: 8050-8. PMID 22623786 DOI: 10.1128/Jvi.00836-12  0.359
2012 Crotty S. The 1-1-1 fallacy. Immunological Reviews. 247: 133-42. PMID 22500837 DOI: 10.1111/J.1600-065X.2012.01117.X  0.412
2012 Kroenke MA, Eto D, Locci M, Cho M, Davidson T, Haddad EK, Crotty S. Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 188: 3734-44. PMID 22427637 DOI: 10.4049/Jimmunol.1103246  0.409
2012 Johnston RJ, Choi YS, Diamond JA, Yang JA, Crotty S. STAT5 is a potent negative regulator of TFH cell differentiation. The Journal of Experimental Medicine. 209: 243-50. PMID 22271576 DOI: 10.1084/Jem.20111174  0.413
2011 Xu C, Meng X, Yan B, Crotty S, Deng J, Xiang Y. An epitope conserved in orthopoxvirus A13 envelope protein is the target of neutralizing and protective antibodies. Virology. 418: 67-73. PMID 21810533 DOI: 10.1016/J.Virol.2011.06.029  0.369
2011 Choi YS, Kageyama R, Eto D, Escobar TC, Johnston RJ, Monticelli L, Lao C, Crotty S. ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity. 34: 932-46. PMID 21636296 DOI: 10.1016/J.Immuni.2011.03.023  0.413
2011 Salek-Ardakani S, Choi YS, Rafii-El-Idrissi Benhnia M, Flynn R, Arens R, Shoenberger S, Crotty S, Croft M, Salek-Ardakani S. B cell-specific expression of B7-2 is required for follicular Th cell function in response to vaccinia virus. Journal of Immunology (Baltimore, Md. : 1950). 186: 5294-303. PMID 21441451 DOI: 10.4049/Jimmunol.1100406  0.439
2011 Eto D, Lao C, DiToro D, Barnett B, Escobar TC, Kageyama R, Yusuf I, Crotty S. IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation. Plos One. 6: e17739. PMID 21423809 DOI: 10.1371/Journal.Pone.0017739  0.311
2011 Crotty S. Follicular helper CD4 T cells (TFH). Annual Review of Immunology. 29: 621-63. PMID 21314428 DOI: 10.1146/Annurev-Immunol-031210-101400  0.424
2011 Tomimori Y, Kawakami Y, McCausland MM, Ando T, Koriazova L, Kato S, Kawakami T, Crotty S. Protective murine and human monoclonal antibodies against eczema vaccinatum. Antiviral Therapy. 16: 67-75. PMID 21311110 DOI: 10.3851/Imp1717  0.383
2010 McCausland MM, Benhnia MREI, Crickard L, Laudenslager J, Granger SW, Tahara T, Kubo R, Koriazova L, Kato S, Crotty S. Combination therapy of vaccinia virus infection with human anti-H3 and anti-B5 monoclonal antibodies in a small animal model Antiviral Therapy. 15: 661-675. PMID 20587859 DOI: 10.3851/Imp1573  0.398
2010 Yusuf I, Kageyama R, Monticelli L, Johnston RJ, Ditoro D, Hansen K, Barnett B, Crotty S. Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150). Journal of Immunology (Baltimore, Md. : 1950). 185: 190-202. PMID 20525889 DOI: 10.4049/Jimmunol.0903505  0.398
2010 Poholek AC, Hansen K, Hernandez SG, Eto D, Chandele A, Weinstein JS, Dong X, Odegard JM, Kaech SM, Dent AL, Crotty S, Craft J. In vivo regulation of Bcl6 and T follicular helper cell development. Journal of Immunology (Baltimore, Md. : 1950). 185: 313-26. PMID 20519643 DOI: 10.4049/Jimmunol.0904023  0.385
2010 Kotturi MF, Botten J, Maybeno M, Sidney J, Glenn J, Bui HH, Oseroff C, Crotty S, Peters B, Grey H, Altmann DM, Buchmeier MJ, Sette A. Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage. Immunome Research. 6: 4. PMID 20478058 DOI: 10.1186/1745-7580-6-4  0.48
2010 Moutaftsi M, Tscharke DC, Vaughan K, Koelle DM, Stern L, Calvo-Calle M, Ennis F, Terajima M, Sutter G, Crotty S, Drexler I, Franchini G, Yewdell JW, Head SR, Blum J, et al. Uncovering the interplay between CD8, CD4 and antibody responses to complex pathogens. Future Microbiology. 5: 221-39. PMID 20143946 DOI: 10.2217/Fmb.09.110  0.423
2010 Crotty S, Johnston RJ, Schoenberger SP. Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation. Nature Immunology. 11: 114-20. PMID 20084069 DOI: 10.1038/Ni.1837  0.379
2009 Sette A, Grey H, Oseroff C, Peters B, Moutaftsi M, Crotty S, Assarsson E, Greenbaum J, Kim Y, Kolla R, Tscharke D, Koelle D, Johnson RP, Blum J, Head S, et al. Definition of epitopes and antigens recognized by vaccinia specific immune responses: their conservation in variola virus sequences, and use as a model system to study complex pathogens. Vaccine. 27: G21-6. PMID 20006135 DOI: 10.1016/J.Vaccine.2009.10.011  0.47
2009 Moyron-Quiroz JE, McCausland MM, Kageyama R, Sette A, Crotty S. The smallpox vaccine induces an early neutralizing IgM response. Vaccine. 28: 140-7. PMID 19822230 DOI: 10.1016/J.Vaccine.2009.09.086  0.42
2009 Benhnia MREI, McCausland MM, Laudenslager J, Granger SW, Rickert S, Koriazova L, Tahara T, Kubo RT, Kato S, Crotty S. Heavily isotype-dependent protective activities of human antibodies against vaccinia virus extracellular virion antigen B5 Journal of Virology. 83: 12355-12367. PMID 19793826 DOI: 10.1128/Jvi.01593-09  0.431
2009 Johnston RJ, Poholek AC, DiToro D, Yusuf I, Eto D, Barnett B, Dent AL, Craft J, Crotty S. Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science (New York, N.Y.). 325: 1006-10. PMID 19608860 DOI: 10.1126/Science.1175870  0.435
2009 Kawakami Y, Tomimori Y, Yumoto K, Hasegawa S, Ando T, Tagaya Y, Crotty S, Kawakami T. Inhibition of NK cell activity by IL-17 allows vaccinia virus to induce severe skin lesions in a mouse model of eczema vaccinatum. The Journal of Experimental Medicine. 206: 1219-25. PMID 19468065 DOI: 10.1084/Jem.20082835  0.384
2009 Benhnia MREI, McCausland MM, Moyron J, Laudenslager J, Granger S, Rickert S, Koriazova L, Kubo R, Kato S, Crotty S. Vaccinia virus extracellular enveloped virion neutralization in vitro and protection in vivo depend on complement Journal of Virology. 83: 1201-1215. PMID 19019965 DOI: 10.1128/Jvi.01797-08  0.444
2008 Tupin E, Benhnia MR, Kinjo Y, Patsey R, Lena CJ, Haller MC, Caimano MJ, Imamura M, Wong CH, Crotty S, Radolf JD, Sellati TJ, Kronenberg M. NKT cells prevent chronic joint inflammation after infection with Borrelia burgdorferi. Proceedings of the National Academy of Sciences of the United States of America. 105: 19863-8. PMID 19060201 DOI: 10.1073/Pnas.0810519105  0.432
2008 Salek-Ardakani S, Moutaftsi M, Crotty S, Sette A, Croft M. OX40 drives protective vaccinia virus-specific CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 7969-76. PMID 19017988 DOI: 10.4049/Jimmunol.181.11.7969  0.435
2008 Sette A, Moutaftsi M, Moyron-Quiroz J, McCausland MM, Davies DH, Johnston RJ, Peters B, Rafii-El-Idrissi Benhnia M, Hoffmann J, Su HP, Singh K, Garboczi DN, Head S, Grey H, Felgner PL, ... Crotty S, et al. Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities. Immunity. 28: 847-58. PMID 18549802 DOI: 10.1016/J.Immuni.2008.04.018  0.51
2008 Benhnia MR, McCausland MM, Su HP, Singh K, Hoffmann J, Davies DH, Felgner PL, Head S, Sette A, Garboczi DN, Crotty S. Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine. Journal of Virology. 82: 3751-68. PMID 18234801 DOI: 10.1128/Jvi.02244-07  0.389
2008 McCausland MM, Crotty S. Quantitative PCR technique for detecting lymphocytic choriomeningitis virus in vivo. Journal of Virological Methods. 147: 167-76. PMID 17920702 DOI: 10.1016/J.Jviromet.2007.08.025  0.31
2007 Karem KL, Reynolds M, Hughes C, Braden Z, Nigam P, Crotty S, Glidewell J, Ahmed R, Amara R, Damon IK. Monkeypox-induced immunity and failure of childhood smallpox vaccination to provide complete protection. Clinical and Vaccine Immunology : Cvi. 14: 1318-27. PMID 17715329 DOI: 10.1128/Cvi.00148-07  0.412
2007 Mothé BR, Stewart BS, Oseroff C, Bui HH, Stogiera S, Garcia Z, Dow C, Rodriguez-Carreno MP, Kotturi M, Pasquetto V, Botten J, Crotty S, Janssen E, Buchmeier MJ, Sette A. Chronic lymphocytic choriomeningitis virus infection actively down-regulates CD4+ T cell responses directed against a broad range of epitopes. Journal of Immunology (Baltimore, Md. : 1950). 179: 1058-67. PMID 17617598 DOI: 10.4049/Jimmunol.179.2.1058  0.426
2007 Moutaftsi M, Bui HH, Peters B, Sidney J, Salek-Ardakani S, Oseroff C, Pasquetto V, Crotty S, Croft M, Lefkowitz EJ, Grey H, Sette A. Vaccinia virus-specific CD4+ T cell responses target a set of antigens largely distinct from those targeted by CD8+ T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 178: 6814-20. PMID 17513729 DOI: 10.4049/Jimmunol.178.11.6814  0.421
2007 Davies DH, Molina DM, Wrammert J, Miller J, Hirst S, Mu Y, Pablo J, Unal B, Nakajima-Sasaki R, Liang X, Crotty S, Karem KL, Damon IK, Ahmed R, Villarreal L, et al. Proteome-wide analysis of the serological response to vaccinia and smallpox. Proteomics. 7: 1678-86. PMID 17443847 DOI: 10.1002/Pmic.200600926  0.41
2007 McCausland MM, Yusuf I, Tran H, Ono N, Yanagi Y, Crotty S. SAP regulation of follicular helper CD4 T cell development and humoral immunity is independent of SLAM and Fyn kinase. Journal of Immunology (Baltimore, Md. : 1950). 178: 817-28. PMID 17202343 DOI: 10.4049/Jimmunol.178.2.817  0.435
2006 Ejrnaes M, Filippi CM, Martinic MM, Ling EM, Togher LM, Crotty S, von Herrath MG. Resolution of a chronic viral infection after interleukin-10 receptor blockade. The Journal of Experimental Medicine. 203: 2461-72. PMID 17030951 DOI: 10.1084/Jem.20061462  0.381
2006 Amanna IJ, Slifka MK, Crotty S. Immunity and immunological memory following smallpox vaccination. Immunological Reviews. 211: 320-37. PMID 16824139 DOI: 10.1111/J.0105-2896.2006.00392.X  0.427
2006 Crotty S, McCausland MM, Aubert RD, Wherry EJ, Ahmed R. Hypogammaglobulinemia and exacerbated CD8 T-cell-mediated immunopathology in SAP-deficient mice with chronic LCMV infection mimics human XLP disease. Blood. 108: 3085-93. PMID 16788096 DOI: 10.1182/Blood-2006-04-018929  0.432
2006 Cannons JL, Yu LJ, Jankovic D, Crotty S, Horai R, Kirby M, Anderson S, Cheever AW, Sher A, Schwartzberg PL. SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation. The Journal of Experimental Medicine. 203: 1551-65. PMID 16754717 DOI: 10.1084/Jem.20052097  0.447
2006 Graham DB, Bell MP, McCausland MM, Huntoon CJ, van Deursen J, Faubion WA, Crotty S, McKean DJ. Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 176: 291-300. PMID 16365421 DOI: 10.4049/Jimmunol.176.1.291  0.371
2005 Davies DH, McCausland MM, Valdez C, Huynh D, Hernandez JE, Mu Y, Hirst S, Villarreal L, Felgner PL, Crotty S. Vaccinia virus H3L envelope protein is a major target of neutralizing antibodies in humans and elicits protection against lethal challenge in mice. Journal of Virology. 79: 11724-33. PMID 16140750 DOI: 10.1128/Jvi.79.18.11724-11733.2005  0.434
2005 Regoes RR, Crotty S, Antia R, Tanaka MM. Optimal replication of poliovirus within cells. The American Naturalist. 165: 364-73. PMID 15729666 DOI: 10.1086/428295  0.34
2005 Davies DH, Liang X, Hernandez JE, Randall A, Hirst S, Mu Y, Romero KM, Nguyen TT, Kalantari-Dehaghi M, Crotty S, Baldi P, Villarreal LP, Felgner PL. Profiling the humoral immune response to infection by using proteome microarrays: high-throughput vaccine and diagnostic antigen discovery. Proceedings of the National Academy of Sciences of the United States of America. 102: 547-52. PMID 15647345 DOI: 10.1073/Pnas.0408782102  0.436
2004 Quinn CP, Dull PM, Semenova V, Li H, Crotty S, Taylor TH, Steward-Clark E, Stamey KL, Schmidt DS, Stinson KW, Freeman AE, Elie CM, Martin SK, Greene C, Aubert RD, et al. Immune responses to Bacillus anthracis protective antigen in patients with bioterrorism-related cutaneous or inhalation anthrax. The Journal of Infectious Diseases. 190: 1228-36. PMID 15346332 DOI: 10.1086/423937  0.318
2004 Crotty S, Ahmed R. Immunological memory in humans. Seminars in Immunology. 16: 197-203. PMID 15130504 DOI: 10.1016/J.Smim.2004.02.008  0.35
2004 Crotty S, Aubert RD, Glidewell J, Ahmed R. Tracking human antigen-specific memory B cells: a sensitive and generalized ELISPOT system. Journal of Immunological Methods. 286: 111-22. PMID 15087226 DOI: 10.1016/J.Jim.2003.12.015  0.404
2004 Crotty S, Andino R. Poliovirus vaccine strains as mucosal vaccine vectors and their potential use to develop an AIDS vaccine. Advanced Drug Delivery Reviews. 56: 835-52. PMID 15063593 DOI: 10.1016/J.Addr.2003.10.042  0.627
2004 Crotty S, Saleh MC, Gitlin L, Beske O, Andino R. The poliovirus replication machinery can escape inhibition by an antiviral drug that targets a host cell protein. Journal of Virology. 78: 3378-86. PMID 15016860 DOI: 10.1128/Jvi.78.7.3378-3386.2004  0.712
2003 Crotty S, Felgner P, Davies H, Glidewell J, Villarreal L, Ahmed R. Cutting edge: long-term B cell memory in humans after smallpox vaccination. Journal of Immunology (Baltimore, Md. : 1950). 171: 4969-73. PMID 14607890 DOI: 10.4049/Jimmunol.171.10.4969  0.415
2003 Crotty S, Gohara D, Gilligan DK, Karelsky S, Cameron CE, Andino R. Manganese-dependent polioviruses caused by mutations within the viral polymerase. Journal of Virology. 77: 5378-88. PMID 12692240 DOI: 10.1128/Jvi.77.9.5378-5388.2003  0.57
2003 Crotty S, Kersh EN, Cannons J, Schwartzberg PL, Ahmed R. SAP is required for generating long-term humoral immunity. Nature. 421: 282-7. PMID 12529646 DOI: 10.1038/Nature01318  0.485
2003 Crotty S, Andino R. Virus-based vectors for gene expression in mammalian cells: Poliovirus New Comprehensive Biochemistry. 38: 169-187. DOI: 10.1016/S0167-7306(03)38011-1  0.606
2002 Crotty S, Andino R. Implications of high RNA virus mutation rates: lethal mutagenesis and the antiviral drug ribavirin. Microbes and Infection / Institut Pasteur. 4: 1301-7. PMID 12443894 DOI: 10.1016/S1286-4579(02)00008-4  0.59
2002 Crotty S, Hix L, Sigal LJ, Andino R. Poliovirus pathogenesis in a new poliovirus receptor transgenic mouse model: age-dependent paralysis and a mucosal route of infection. The Journal of General Virology. 83: 1707-20. PMID 12075090 DOI: 10.1099/0022-1317-83-7-1707  0.529
2002 Crotty S, Cameron C, Andino R. Ribavirin's antiviral mechanism of action: lethal mutagenesis? Journal of Molecular Medicine (Berlin, Germany). 80: 86-95. PMID 11907645 DOI: 10.1007/S00109-001-0308-0  0.59
2001 Crotty S, Miller CJ, Lohman BL, Neagu MR, Compton L, Lu D, Lü FX, Fritts L, Lifson JD, Andino R. Protection against simian immunodeficiency virus vaginal challenge by using Sabin poliovirus vectors. Journal of Virology. 75: 7435-52. PMID 11462016 DOI: 10.1128/Jvi.75.16.7435-7452.2001  0.602
2001 Crotty S, Cameron CE, Andino R. RNA virus error catastrophe: direct molecular test by using ribavirin. Proceedings of the National Academy of Sciences of the United States of America. 98: 6895-900. PMID 11371613 DOI: 10.1073/Pnas.111085598  0.583
2000 Crotty S, Maag D, Arnold JJ, Zhong W, Lau JY, Hong Z, Andino R, Cameron CE. The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen. Nature Medicine. 6: 1375-9. PMID 11100123 DOI: 10.1038/82191  0.59
2000 Gohara DW, Crotty S, Arnold JJ, Yoder JD, Andino R, Cameron CE. Poliovirus RNA-dependent RNA polymerase (3Dpol): structural, biochemical, and biological analysis of conserved structural motifs A and B. The Journal of Biological Chemistry. 275: 25523-32. PMID 10827187 DOI: 10.1074/Jbc.M002671200  0.555
1999 Crotty S, Lohman BL, Lü FX, Tang S, Miller CJ, Andino R. Mucosal immunization of cynomolgus macaques with two serotypes of live poliovirus vectors expressing simian immunodeficiency virus antigens: stimulation of humoral, mucosal, and cellular immunity. Journal of Virology. 73: 9485-95. PMID 10516057 DOI: 10.1128/Jvi.73.11.9485-9495.1999  0.646
1999 Sigal LJ, Crotty S, Andino R, Rock KL. Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen. Nature. 398: 77-80. PMID 10078533 DOI: 10.1038/18038  0.633
1998 Smith CA, Crotty S, Harada Y, Frankel AD. Altering the context of an RNA bulge switches the binding specificities of two viral Tat proteins Biochemistry. 37: 10808-10814. PMID 9692971 DOI: 10.1021/Bi980382+  0.33
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