Paul E. Klotman - Publications

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Microbiology Biology, Immunology, Mathematics

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Chen Y, Chen Y, Fu J, Sun Z, Li H, Xiao W, E J, Lo BY, Wang N, Zhang W, Klotman M, Klotman P, Kopp JB, D'Agati VD, He JC, et al. Tubular-specific expression of HIV protein Vpr leads to severe tubulointerstitial damage accompanied by progressive fibrosis and cystic development. Kidney International. PMID 36565808 DOI: 10.1016/j.kint.2022.12.012  0.457
2020 Wang X, Liu R, Zhang W, Hyink DP, Das GC, Das B, Li Z, Wang A, Yuan W, Klotman PE, Lee K, He JC. Role of SIRT1 in HIV-associated kidney disease. American Journal of Physiology. Renal Physiology. PMID 32657157 DOI: 10.1152/Ajprenal.00140.2020  0.573
2020 Blasi M, Stadtler H, Chang J, Hemmersbach-Miller M, Wyatt C, Klotman P, Gao F, Wolfe C, Klotman M. Detection of Donor's HIV Strain in HIV-Positive Kidney-Transplant Recipient. The New England Journal of Medicine. 382: 195-197. PMID 31914248 DOI: 10.1056/Nejmc1910189  0.502
2018 Li H, Zhang W, Zhong F, Das GC, Xie Y, Li Z, Cai W, Jiang G, Choi J, Sidani M, Hyink DP, Lee K, Klotman PE, He JC. Epigenetic regulation of RCAN1 expression in kidney disease and its role in podocyte injury. Kidney International. PMID 30366682 DOI: 10.1016/J.Kint.2018.07.023  0.518
2018 Cheung JY, Gordon J, Wang J, Song J, Zhang XQ, Prado FJ, Shanmughapriya S, Rajan S, Tomar D, Tahrir FG, Gupta MK, Knezevic T, Merabova N, Kontos CD, McClung JM, ... Klotman PE, et al. Mitochondrial dysfunction in human immunodeficiency virus-1 transgenic mouse cardiac myocytes. Journal of Cellular Physiology. PMID 30256393 DOI: 10.1002/Jcp.27232  0.345
2015 Razzak Chaudhary S, Workeneh BT, Montez-Rath ME, Zolopa AR, Klotman PE, Winkelmayer WC. Trends in the outcomes of end-stage renal disease secondary to human immunodeficiency virus-associated nephropathy. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 30: 1734-40. PMID 26175146 DOI: 10.1093/Ndt/Gfv207  0.357
2014 Hays T, Ma'ayan A, Clark NR, Tan CM, Teixeira A, Teixeira A, Choi JW, Burdis N, Jung SY, Bajaj AO, O'Malley BW, He JC, Hyink DP, Klotman PE. Proteomics analysis of the non-muscle myosin heavy chain IIa-enriched actin-myosin complex reveals multiple functions within the podocyte. Plos One. 9: e100660. PMID 24949636 DOI: 10.1371/Journal.Pone.0100660  0.576
2014 Potla U, Ni J, Vadaparampil J, Yang G, Leventhal JS, Campbell KN, Chuang PY, Morozov A, He JC, D'Agati VD, Klotman PE, Kaufman L. Podocyte-specific RAP1GAP expression contributes to focal segmental glomerulosclerosis-associated glomerular injury. The Journal of Clinical Investigation. 124: 1757-69. PMID 24642466 DOI: 10.1172/Jci67846  0.344
2013 Wyatt CM, Schwartz GJ, Owino Ong'or W, Abuya J, Abraham AG, Mboku C, M'mene LB, Koima WJ, Hotta M, Maier P, Klotman PE, Wools-Kaloustian K. Estimating kidney function in HIV-infected adults in Kenya: comparison to a direct measure of glomerular filtration rate by iohexol clearance. Plos One. 8: e69601. PMID 23950899 DOI: 10.1371/Journal.Pone.0069601  0.477
2013 Zhong Y, Chen EY, Liu R, Chuang PY, Mallipattu SK, Tan CM, Clark NR, Deng Y, Klotman PE, Ma'ayan A, He JC. Renoprotective effect of combined inhibition of angiotensin-converting enzyme and histone deacetylase. Journal of the American Society of Nephrology : Jasn. 24: 801-11. PMID 23559582 DOI: 10.1681/Asn.2012060590  0.391
2013 Sharma M, Magenheimer LK, Home T, Tamano KN, Singhal PC, Hyink DP, Klotman PE, Vanden Heuvel GB, Fields TA. Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy. American Journal of Physiology. Renal Physiology. 304: F1127-36. PMID 23389453 DOI: 10.1152/Ajprenal.00475.2012  0.401
2013 Gu L, Dai Y, Xu J, Mallipattu S, Kaufman L, Klotman PE, He JC, Chuang PY. Deletion of podocyte STAT3 mitigates the entire spectrum of HIV-1-associated nephropathy. Aids (London, England). 27: 1091-8. PMID 23343908 DOI: 10.1097/Qad.0B013E32835F1Ea1  0.537
2013 Mallipattu SK, Liu R, Zhong Y, Chen EY, D'Agati V, Kaufman L, Ma'ayan A, Klotman PE, Chuang PY, He JC. Expression of HIV transgene aggravates kidney injury in diabetic mice. Kidney International. 83: 626-34. PMID 23325078 DOI: 10.1038/Ki.2012.445  0.454
2013 Lipkowitz MS, Freedman BI, Langefeld CD, Comeau ME, Bowden DW, Kao WH, Astor BC, Bottinger EP, Iyengar SK, Klotman PE, Freedman RG, Zhang W, Parekh RS, Choi MJ, Nelson GW, et al. Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans. Kidney International. 83: 114-20. PMID 22832513 DOI: 10.1038/Ki.2012.263  0.344
2012 Mallipattu SK, Liu R, Zheng F, Narla G, Ma'ayan A, Dikman S, Jain MK, Saleem M, D'Agati V, Klotman P, Chuang PY, He JC. Kruppel-like factor 15 (KLF15) is a key regulator of podocyte differentiation. The Journal of Biological Chemistry. 287: 19122-35. PMID 22493483 DOI: 10.1074/Jbc.M112.345983  0.408
2012 Hays T, D'Agati VD, Garellek JA, Warren T, Trubin ME, Hyink DP, He JC, Klotman PE. Glomerular MYH9 expression is reduced by HIV-1. Aids (London, England). 26: 797-803. PMID 22313957 DOI: 10.1097/Qad.0B013E328351F6Cf  0.715
2012 Zhong Y, Wu Y, Liu R, Deng Y, Mallipattu SK, Klotman PE, Chuang PY, He JC. Roflumilast enhances the renal protective effects of retinoids in an HIV-1 transgenic mouse model of rapidly progressive renal failure. Kidney International. 81: 856-64. PMID 22258322 DOI: 10.1038/Ki.2011.467  0.536
2012 Wyatt CM, Meliambro K, Klotman PE. Recent progress in HIV-associated nephropathy. Annual Review of Medicine. 63: 147-59. PMID 21888512 DOI: 10.1146/Annurev-Med-041610-134224  0.562
2012 Inrig JK, Szczech LA, Gerntholtz TE, Klotman PE. Renal complications of HIV infection Sande's Hiv/Aids Medicine: Medical Management of Aids 2013: Second Edition. 287-295. DOI: 10.1016/B978-1-4557-0695-2.00023-7  0.448
2011 Papeta N, Kiryluk K, Patel A, Sterken R, Kacak N, Snyder HJ, Imus PH, Mhatre AN, Lawani AK, Julian BA, Wyatt RJ, Novak J, Wyatt CM, Ross MJ, Winston JA, ... ... Klotman PE, et al. APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy. Journal of the American Society of Nephrology : Jasn. 22: 1991-6. PMID 21997397 DOI: 10.1681/Asn.2011040434  0.433
2011 Wyatt CM, Hoover DR, Shi Q, Tien PC, Karim R, Cohen MH, Goderre JL, Seaberg EC, Lazar J, Young MA, Klotman PE, Anastos K. Pre-existing albuminuria predicts AIDS and non-AIDS mortality in women initiating antiretroviral therapy. Antiviral Therapy. 16: 591-6. PMID 21685547 DOI: 10.3851/Imp1766  0.422
2011 Medapalli RK, He JC, Klotman PE. HIV-associated nephropathy: pathogenesis. Current Opinion in Nephrology and Hypertension. 20: 306-11. PMID 21358326 DOI: 10.1097/Mnh.0B013E328345359A  0.507
2011 Hostetter TH, Kochis DJ, Shaffer RN, Chertow G, Harmon WE, Klotman PE, Powe NR, Sedor JR, Smedberg PC, Watnick S, Winkelmayer WC. World Kidney Day 2011. Journal of the American Society of Nephrology : Jasn. 22: 397-8. PMID 21355055 DOI: 10.1681/Asn.2011020115  0.335
2011 Chen P, Chen BK, Mosoian A, Hays T, Ross MJ, Klotman PE, Klotman ME. Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells. Journal of the American Society of Nephrology : Jasn. 22: 496-507. PMID 21335514 DOI: 10.1681/Asn.2010040379  0.697
2011 Ratnam KK, Feng X, Chuang PY, Verma V, Lu TC, Wang J, Jin Y, Farias EF, Napoli JL, Chen N, Kaufman L, Takano T, D'Agati VD, Klotman PE, He JC. Role of the retinoic acid receptor-α in HIV-associated nephropathy. Kidney International. 79: 624-34. PMID 21150871 DOI: 10.1038/Ki.2010.470  0.454
2010 Villarroya J, Diaz-Delfin J, Hyink D, Domingo P, Giralt M, Klotman PE, Villarroya F. HIV type-1 transgene expression in mice alters adipose tissue and adipokine levels: towards a rodent model of HIV type-1 lipodystrophy. Antiviral Therapy. 15: 1021-8. PMID 21041917 DOI: 10.3851/Imp1669  0.52
2010 Kaufman L, Potla U, Coleman S, Dikiy S, Hata Y, Kurihara H, He JC, D'Agati VD, Klotman PE. Up-regulation of the homophilic adhesion molecule sidekick-1 in podocytes contributes to glomerulosclerosis. The Journal of Biological Chemistry. 285: 25677-85. PMID 20562105 DOI: 10.1074/Jbc.M110.133959  0.365
2010 Mosoian A, Teixeira A, Burns CS, Sander LE, Gusella GL, He C, Blander JM, Klotman P, Klotman ME. Prothymosin-alpha inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction. Proceedings of the National Academy of Sciences of the United States of America. 107: 10178-83. PMID 20479248 DOI: 10.1073/Pnas.0914870107  0.405
2010 Snyder A, Alsauskas ZC, Leventhal JS, Rosenstiel PE, Gong P, Chan JJ, Barley K, He JC, Klotman ME, Ross MJ, Klotman PE. HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells. Aids (London, England). 24: 1107-19. PMID 20404718 DOI: 10.1097/Qad.0B013E328337B0Ab  0.387
2010 Wyatt CM, Hoover DR, Shi Q, Seaberg E, Wei C, Tien PC, Karim R, Lazar J, Young MA, Cohen MH, Klotman PE, Anastos K. Microalbuminuria is associated with all-cause and AIDS mortality in women with HIV infection. Journal of Acquired Immune Deficiency Syndromes (1999). 55: 73-7. PMID 20098331 DOI: 10.1097/Qai.0B013E3181Cc1070  0.454
2010 Kaufman L, Collins SE, Klotman PE. The pathogenesis of HIV-associated nephropathy. Advances in Chronic Kidney Disease. 17: 36-43. PMID 20005487 DOI: 10.1053/J.Ackd.2009.08.012  0.565
2009 Snyder A, Alsauskas Z, Gong P, Rosenstiel PE, Klotman ME, Klotman PE, Ross MJ. FAT10: a novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy. Journal of Virology. 83: 11983-8. PMID 19726511 DOI: 10.1128/Jvi.00034-09  0.495
2009 Rosenstiel PE, Chan J, Snyder A, Planelles V, D'Agati VD, Klotman PE, Klotman ME. HIV-1 Vpr activates the DNA damage response in renal tubule epithelial cells. Aids (London, England). 23: 2054-6. PMID 19657269 DOI: 10.1097/Qad.0B013E32833088A0  0.532
2009 Paragas N, Nickolas TL, Wyatt C, Forster CS, Sise M, Morgello S, Jagla B, Buchen C, Stella P, Sanna-Cherchi S, Carnevali ML, Mattei S, Bovino A, Argentiero L, Magnano A, ... ... Klotman P, et al. Urinary NGAL marks cystic disease in HIV-associated nephropathy. Journal of the American Society of Nephrology : Jasn. 20: 1687-92. PMID 19628667 DOI: 10.1681/Asn.2009010065  0.563
2009 Feng X, Lu TC, Chuang PY, Fang W, Ratnam K, Xiong H, Ouyang X, Shen Y, Levy DE, Hyink D, Klotman M, D'Agati V, Iyengar R, Klotman PE, He JC. Reduction of Stat3 activity attenuates HIV-induced kidney injury. Journal of the American Society of Nephrology : Jasn. 20: 2138-46. PMID 19608706 DOI: 10.1681/Asn.2008080879  0.45
2009 Rosenstiel P, Gharavi A, D'Agati V, Klotman P. Transgenic and infectious animal models of HIV-associated nephropathy. Journal of the American Society of Nephrology : Jasn. 20: 2296-304. PMID 19497967 DOI: 10.1681/Asn.2008121230  0.538
2009 Papeta N, Chan KT, Prakash S, Martino J, Kiryluk K, Ballard D, Bruggeman LA, Frankel R, Zheng Z, Klotman PE, Zhao H, D'Agati VD, Lifton RP, Gharavi AG. Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression. The Journal of Clinical Investigation. 119: 1178-88. PMID 19381020 DOI: 10.1172/Jci37131  0.498
2009 Szczech LA, Harmon W, Hostetter TH, Klotman PE, Powe NR, Sedor JR, Smedberg P, Himmelfarb J. World Kidney Day 2009: problems and challenges in the emerging epidemic of kidney disease. Journal of the American Society of Nephrology : Jasn. 20: 453-5. PMID 19244576 DOI: 10.1681/Asn.2009010041  0.348
2009 Abbadessa G, Accolla R, Aiuti F, Albini A, Aldovini A, Alfano M, Antonelli G, Bartholomew C, Bentwich Z, Bertazzoni U, Berzofsky JA, Biberfeld P, Boeri E, Buonaguro L, Buonaguro FM, ... ... Klotman P, et al. Unsung hero Robert C. Gallo. Science (New York, N.Y.). 323: 206-7. PMID 19131607 DOI: 10.1126/Science.323.5911.206  0.431
2009 Chan KT, Papeta N, Martino J, Zheng Z, Frankel RZ, Klotman PE, D'Agati VD, Lifton RP, Gharavi AG. Accelerated development of collapsing glomerulopathy in mice congenic for the HIVAN1 locus. Kidney International. 75: 366-72. PMID 19092797 DOI: 10.1038/Ki.2008.625  0.363
2009 Wyatt CM, Morgello S, Katz-Malamed R, Wei C, Klotman ME, Klotman PE, D'Agati VD. The spectrum of kidney disease in patients with AIDS in the era of antiretroviral therapy. Kidney International. 75: 428-34. PMID 19052538 DOI: 10.1038/Ki.2008.604  0.535
2008 Ratnam KK, He CJ, Klotman P. Nef as a Proliferative Factor for Kidney Epithelial Cells in HIV-Associated Nephropathy. Clinical Medicine. Oncology. 2: 539-45. PMID 21892329 DOI: 10.4137/Cmo.S661  0.574
2008 Wyatt CM, Klotman PE, D'Agati VD. HIV-associated nephropathy: clinical presentation, pathology, and epidemiology in the era of antiretroviral therapy. Seminars in Nephrology. 28: 513-22. PMID 19013322 DOI: 10.1016/J.Semnephrol.2008.08.005  0.571
2008 Wyatt CM, Klotman PE. Kidney disease in HIV infection: introduction. Seminars in Nephrology. 28: 511-2. PMID 19013321 DOI: 10.1016/J.Semnephrol.2008.08.004  0.564
2008 Wyatt CM, Malvestutto C, Coca SG, Klotman PE, Parikh CR. The impact of hepatitis C virus coinfection on HIV-related kidney disease: a systematic review and meta-analysis. Aids (London, England). 22: 1799-807. PMID 18753863 DOI: 10.1097/Qad.0B013E32830E0152  0.458
2008 Lu TC, Wang Z, Feng X, Chuang P, Fang W, Chen Y, Neves S, Maayan A, Xiong H, Liu Y, Iyengar R, Klotman PE, He JC. Retinoic acid utilizes CREB and USF1 in a transcriptional feed-forward loop in order to stimulate MKP1 expression in human immunodeficiency virus-infected podocytes. Molecular and Cellular Biology. 28: 5785-94. PMID 18625721 DOI: 10.1128/Mcb.00245-08  0.42
2008 Rosenstiel PE, Gruosso T, Letourneau AM, Chan JJ, LeBlanc A, Husain M, Najfeld V, Planelles V, D'Agati VD, Klotman ME, Klotman PE. HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells. Kidney International. 74: 1049-58. PMID 18614999 DOI: 10.1038/Ki.2008.303  0.553
2008 Korgaonkar SN, Feng X, Ross MD, Lu TC, D'Agati V, Iyengar R, Klotman PE, He JC. HIV-1 upregulates VEGF in podocytes. Journal of the American Society of Nephrology : Jasn. 19: 877-83. PMID 18443354 DOI: 10.1681/Asn.2007050629  0.497
2008 Wyatt CM, Rosenstiel PE, Klotman PE. HIV-associated nephropathy. Contributions to Nephrology. 159: 151-61. PMID 18391591 DOI: 10.1159/000125831  0.572
2008 Lu TC, He JC, Wang ZH, Feng X, Fukumi-Tominaga T, Chen N, Xu J, Iyengar R, Klotman PE. HIV-1 Nef disrupts the podocyte actin cytoskeleton by interacting with diaphanous interacting protein. The Journal of Biological Chemistry. 283: 8173-82. PMID 18234668 DOI: 10.1074/Jbc.M708920200  0.434
2008 Serrano AL, Jardi M, Suelves M, Klotman PE, Munoz-Canoves P. HIV-1 transgenic expression in mice induces selective atrophy of fast-glycolytic skeletal muscle fibers. Frontiers in Bioscience : a Journal and Virtual Library. 13: 2797-805. PMID 17981754 DOI: 10.2741/2886  0.334
2008 Radbill BD, Wyatt CM, Vassalotti JA, Klotman ME, Klotman PE. Hepatitis B- and HIV-Related Renal Diseases Therapy in Nephrology & Hypertension. 272-280. DOI: 10.1016/B978-141605484-9.50026-5  0.408
2008 Ross MJ, Klotman PE. Pathogenesis of HIV-Associated nephropathy Molecular and Genetic Basis of Renal Disease. 419-434. DOI: 10.1016/B978-1-4160-0252-9.50027-6  0.437
2007 Wyatt CM, Winston JA, Malvestutto CD, Fishbein DA, Barash I, Cohen AJ, Klotman ME, Klotman PE. Chronic kidney disease in HIV infection: an urban epidemic. Aids (London, England). 21: 2101-3. PMID 17885301 DOI: 10.1097/Qad.0B013E3282Ef1Bb4  0.499
2007 Wyatt CM, Klotman PE. HIV-1 and HIV-Associated Nephropathy 25 Years Later. Clinical Journal of the American Society of Nephrology : Cjasn. 2: S20-4. PMID 17699507 DOI: 10.2215/Cjn.03561006  0.554
2007 Mosoian A, Teixeira A, Burns CS, Khitrov G, Zhang W, Gusella L, Klotman P, Klotman M. Influence of prothymosin-alpha on HIV-1 target cells. Annals of the New York Academy of Sciences. 1112: 269-85. PMID 17600282 DOI: 10.1196/Annals.1415.043  0.483
2007 Lu TC, He JC, Klotman PE. Podocytes in HIV-associated nephropathy. Nephron. Clinical Practice. 106: c67-71. PMID 17570932 DOI: 10.1159/000101800  0.543
2007 Wyatt CM, Klotman PE. HIV-associated nephropathy in the era of antiretroviral therapy. The American Journal of Medicine. 120: 488-92. PMID 17524746 DOI: 10.1016/J.Amjmed.2007.01.025  0.565
2007 Kaufman L, Yang G, Hayashi K, Ashby JR, Huang L, Ross MJ, Klotman ME, Klotman PE. The homophilic adhesion molecule sidekick-1 contributes to augmented podocyte aggregation in HIV-associated nephropathy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1367-75. PMID 17307840 DOI: 10.1096/Fj.06-7191Com  0.538
2007 He JC, Lu TC, Fleet M, Sunamoto M, Husain M, Fang W, Neves S, Chen Y, Shankland S, Iyengar R, Klotman PE. Retinoic acid inhibits HIV-1-induced podocyte proliferation through the cAMP pathway. Journal of the American Society of Nephrology : Jasn. 18: 93-102. PMID 17182884 DOI: 10.1681/Asn.2006070727  0.535
2006 Shah SN, He CJ, Klotman P. Update on HIV-associated nephropathy. Current Opinion in Nephrology and Hypertension. 15: 450-5. PMID 16775461 DOI: 10.1097/01.Mnh.0000232887.58271.67  0.527
2006 Ross MJ, Fan C, Ross MD, Chu TH, Shi Y, Kaufman L, Zhang W, Klotman ME, Klotman PE. HIV-1 infection initiates an inflammatory cascade in human renal tubular epithelial cells. Journal of Acquired Immune Deficiency Syndromes (1999). 42: 1-11. PMID 16763488 DOI: 10.1097/01.Qai.0000218353.60099.4F  0.566
2006 Wyatt CM, Klotman PE. HIV-associated nephropathy: a case study in race and genetics. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 47: 1084-5; author reply. PMID 16731307 DOI: 10.1053/J.Ajkd.2006.03.043  0.465
2006 Lu TC, He JC, Klotman P. Animal models of HIV-associated nephropathy. Current Opinion in Nephrology and Hypertension. 15: 233-7. PMID 16609288 DOI: 10.1097/01.Mnh.0000222688.69217.8E  0.518
2006 Wyatt CM, Klotman PE. Antiretroviral therapy and the kidney: balancing benefit and risk in patients with HIV infection. Expert Opinion On Drug Safety. 5: 275-87. PMID 16503748 DOI: 10.1517/14740338.5.2.275  0.555
2006 Ross MJ, Wosnitzer MS, Ross MD, Granelli B, Gusella GL, Husain M, Kaufman L, Vasievich M, D'Agati VD, Wilson PD, Klotman ME, Klotman PE. Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease. Journal of the American Society of Nephrology : Jasn. 17: 996-1004. PMID 16495380 DOI: 10.1681/Asn.2005070692  0.542
2006 Zerhouni-Layachi B, Husain M, Ross MJ, Marras D, Sunamoto M, Liu X, Klotman PE, Klotman ME. Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy. Aids (London, England). 20: 621-4. PMID 16470129 DOI: 10.1097/01.Aids.0000210618.68083.8E  0.554
2006 Wyatt CM, Arons RR, Klotman PE, Klotman ME. Acute renal failure in hospitalized patients with HIV: risk factors and impact on in-hospital mortality. Aids (London, England). 20: 561-5. PMID 16470120 DOI: 10.1097/01.Aids.0000210610.52836.07  0.488
2006 Tanji N, Ross MD, Tanji K, Bruggeman LA, Markowitz GS, Klotman PE, D'Agati VD. Detection and localization of HIV-1 DNA in renal tissues by in situ polymerase chain reaction. Histology and Histopathology. 21: 393-401. PMID 16437385 DOI: 10.14670/Hh-21.393  0.49
2005 Husain M, D'Agati VD, He JC, Klotman ME, Klotman PE. HIV-1 Nef induces dedifferentiation of podocytes in vivo: a characteristic feature of HIVAN. Aids (London, England). 19: 1975-80. PMID 16260903 DOI: 10.1097/01.Aids.0000191918.42110.27  0.526
2005 Schwartz EJ, Szczech LA, Ross MJ, Klotman ME, Winston JA, Klotman PE. Highly active antiretroviral therapy and the epidemic of HIV+ end-stage renal disease. Journal of the American Society of Nephrology : Jasn. 16: 2412-20. PMID 15987747 DOI: 10.1681/Asn.2005040340  0.547
2005 Gupta SK, Eustace JA, Winston JA, Boydstun II, Ahuja TS, Rodriguez RA, Tashima KT, Roland M, Franceschini N, Palella FJ, Lennox JL, Klotman PE, Nachman SA, Hall SD, Szczech LA. Guidelines for the management of chronic kidney disease in HIV-infected patients: recommendations of the HIV Medicine Association of the Infectious Diseases Society of America. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 40: 1559-85. PMID 15889353 DOI: 10.1086/430257  0.303
2004 He JC, Husain M, Sunamoto M, D'Agati VD, Klotman ME, Iyengar R, Klotman PE. Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways. The Journal of Clinical Investigation. 114: 643-51. PMID 15343382 DOI: 10.1172/Jci21004  0.506
2004 Szczech LA, Gupta SK, Habash R, Guasch A, Kalayjian R, Appel R, Fields TA, Svetkey LP, Flanagan KH, Klotman PE, Winston JA. The clinical epidemiology and course of the spectrum of renal diseases associated with HIV infection. Kidney International. 66: 1145-52. PMID 15327410 DOI: 10.1111/J.1523-1755.2004.00865.X  0.545
2004 Kaufman L, Hayashi K, Ross MJ, Ross MD, Klotman PE. Sidekick-1 is upregulated in glomeruli in HIV-associated nephropathy. Journal of the American Society of Nephrology : Jasn. 15: 1721-30. PMID 15213259 DOI: 10.1097/01.Asn.0000128975.28958.C2  0.58
2004 Ross MJ, Klotman PE. HIV-associated nephropathy. Aids (London, England). 18: 1089-99. PMID 15166524 DOI: 10.1097/00002030-200405210-00002  0.518
2004 Gharavi AG, Ahmad T, Wong RD, Hooshyar R, Vaughn J, Oller S, Frankel RZ, Bruggeman LA, D'Agati VD, Klotman PE, Lifton RP. Mapping a locus for susceptibility to HIV-1-associated nephropathy to mouse chromosome 3. Proceedings of the National Academy of Sciences of the United States of America. 101: 2488-93. PMID 14983036 DOI: 10.1073/Pnas.0308649100  0.452
2004 Winston JA, Klotman PE, Klotman M. Renal Manifestations of HIV Infection Aids and Other Manifestations of Hiv Infection. 651-661. DOI: 10.1016/B978-012764051-8/50026-3  0.41
2003 Sunamoto M, Husain M, He JC, Schwartz EJ, Klotman PE. Critical role for Nef in HIV-1-induced podocyte dedifferentiation. Kidney International. 64: 1695-701. PMID 14531802 DOI: 10.1046/J.1523-1755.2003.00283.X  0.546
2003 Ross MD, Bruggeman LA, Hanss B, Sunamoto M, Marras D, Klotman ME, Klotman PE. Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy. The Journal of Biological Chemistry. 278: 33248-55. PMID 12796502 DOI: 10.1074/Jbc.M301299200  0.496
2003 Herman ES, Klotman PE. HIV-associated nephropathy: Epidemiology, pathogenesis, and treatment. Seminars in Nephrology. 23: 200-8. PMID 12704580 DOI: 10.1053/snep.2003.50018  0.48
2002 Ross MJ, Klotman PE. Recent progress in HIV-associated nephropathy. Journal of the American Society of Nephrology : Jasn. 13: 2997-3004. PMID 12444220 DOI: 10.1097/01.Asn.0000040750.40907.99  0.557
2002 Klotman P, Klotman M. Editorial comment: renal insufficiency in HIV-infected patients may not always be HIVAN. The Aids Reader. 12: 273. PMID 12138882  0.449
2002 Husain M, Gusella GL, Klotman ME, Gelman IH, Ross MD, Schwartz EJ, Cara A, Klotman PE. HIV-1 Nef induces proliferation and anchorage-independent growth in podocytes. Journal of the American Society of Nephrology : Jasn. 13: 1806-15. PMID 12089376 DOI: 10.1097/01.Asn.0000019642.55998.69  0.554
2002 Schwartz EJ, Fierer DS, Neumann AU, Keller MJ, Parkas V, Zhang DY, Klotman ME, Winston JA, Klotman PE. HIV-1 dynamics in haemodialysis patients. Aids (London, England). 16: 1301-3. PMID 12045502 DOI: 10.1097/00002030-200206140-00019  0.466
2002 Marras D, Bruggeman LA, Gao F, Tanji N, Mansukhani MM, Cara A, Ross MD, Gusella GL, Benson G, D'Agati VD, Hahn BH, Klotman ME, Klotman PE. Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy. Nature Medicine. 8: 522-6. PMID 11984599 DOI: 10.1038/Nm0502-522  0.569
2002 Gusella GL, Fedorova E, Hanss B, Marras D, Klotman ME, Klotman PE. Lentiviral gene transduction of kidney. Human Gene Therapy. 13: 407-14. PMID 11860707 DOI: 10.1089/10430340252792530  0.379
2002 Stern AS, Klotman ME, Ioannou YA, Burrow CR, Wilson PD, Klotman PE, Lipkowitz MS. Polarity of alpha-galactosidase A uptake by renal tubule cells. Kidney International. 61: S52-5. PMID 11841613 DOI: 10.1046/J.1523-1755.2002.0610S1052.X  0.343
2002 Gusella GL, Fedorova E, Marras D, Klotman PE, Klotman ME. In vivo gene transfer to kidney by lentiviral vector. Kidney International. 61: S32-6. PMID 11841609 DOI: 10.1046/J.1523-1755.2002.0610S1032.X  0.34
2002 Woo S, Klotman P. Gene therapy and renal disease. Introduction Kidney International. 61. PMID 11841604 DOI: 10.1046/J.1523-1755.2002.0610S1001.X  0.355
2002 Schwartz EJ, Neumann AU, Teixeira AV, Bruggeman LA, Rappaport J, Perelson AS, Klotman PE. Effect of target cell availability on HIV-1 production in vitro. Aids (London, England). 16: 341-5. PMID 11834944 DOI: 10.1097/00002030-200202150-00004  0.356
2001 Nelson PJ, Gelman IH, Klotman PE. Suppression of HIV-1 expression by inhibitors of cyclin-dependent kinases promotes differentiation of infected podocytes Journal of the American Society of Nephrology. 12: 2827-2831. PMID 11729253  0.433
2001 Ross MJ, Bruggeman LA, Wilson PD, Klotman PE. Microcyst formation and HIV-1 gene expression occur in multiple nephron segments in HIV-associated nephropathy. Journal of the American Society of Nephrology : Jasn. 12: 2645-51. PMID 11729233  0.507
2001 Schwartz EJ, Cara A, Snoeck H, Ross MD, Sunamoto M, Reiser J, Mundel P, Klotman PE. Human immunodeficiency virus-1 induces loss of contact inhibition in podocytes. Journal of the American Society of Nephrology : Jasn. 12: 1677-84. PMID 11461940  0.514
2001 Monahan M, Tanji N, Klotman PE. HIV-associated nephropathy: An urban epidemic Seminars in Nephrology. 21: 394-402. PMID 11455528 DOI: 10.1053/Snep.2001.23771  0.53
2001 Winston JA, Bruggeman LA, Ross MD, Jacobson J, Ross L, D'Agati VD, Klotman PE, Klotman ME. Nephropathy and establishment of a renal reservoir of HIV type 1 during primary infection. The New England Journal of Medicine. 344: 1979-84. PMID 11430327 DOI: 10.1056/Nejm200106283442604  0.572
2001 Bruggeman LA, Adler SH, Klotman PE. Nuclear factor-κB binding to the HIV-1 LTR in kidney: Implications for HIV-associated nephropathy Kidney International. 59: 2174-2181. PMID 11380819 DOI: 10.1046/J.1523-1755.2001.00732.X  0.538
2001 Tanji N, Ross MD, Cara A, Markowitz GS, Klotman PE, D'Agati VD. Effect of tissue processing on the ability to recover nucleic acid from specific renal tissue compartments by laser capture microdissection. Experimental Nephrology. 9: 229-34. PMID 11340308 DOI: 10.1159/000052616  0.356
2000 Ross MJ, Klotman PE, Winston JA. HIV-associated nephropathy: Case study and review of the literature Aids Patient Care and Stds. 14: 637-645. PMID 11119430 DOI: 10.1089/10872910050206559  0.558
2000 Bruggeman LA, Ross MD, Tanji N, Cara A, Dikman S, Gordon RE, Burns GC, D'Agati VD, Winston JA, Klotman ME, Klotman PE. Renal epithelium is a previously unrecognized site of HIV-1 infection. Journal of the American Society of Nephrology : Jasn. 11: 2079-87. PMID 11053484  0.47
2000 Kajiyama W, Kopp JB, Marinos NJ, Klotman PE, Dickie P. Glomerulosclerosis and viral gene expression in HIV-transgenie mice: Role of nef Kidney International. 58: 1148-1159. PMID 10972678 DOI: 10.1046/j.1523-1755.2000.00271.x  0.47
2000 Barisoni L, Bruggeman LA, Mundel P, D'Agati VD, Klotman PE. HIV-1 induces renal epithelial dedifferentiation in a transgenic model of HIV-associated nephropathy Kidney International. 58: 173-181. PMID 10886562 DOI: 10.1046/J.1523-1755.2000.00152.X  0.499
2000 Winston JA, Burns GC, Klotman PE. Treatment of HIV-associated nephropathy Seminars in Nephrology. 20: 293-298. PMID 10855939  0.416
2000 Lewis W, Grupp IL, Grupp G, Hoit B, Morris R, Samarel AM, Bruggeman L, Klotman P. Cardiac dysfunction occurs in the HIV-1 transgenic mouse treated with zidovudine. Laboratory Investigation; a Journal of Technical Methods and Pathology. 80: 187-97. PMID 10701688 DOI: 10.1038/Labinvest.3780022  0.346
1999 Mannon RB, Kopp JB, Ruiz P, Griffiths R, Bustos M, Platt JL, Klotman PE, Coffman TM. Chronic rejection of mouse kidney allografts Kidney International. 55: 1935-1944. PMID 10231457 DOI: 10.1046/J.1523-1755.1999.00423.X  0.303
1999 Winston JA, Klotman ME, Klotman PE. HIV-associated nephropathy is a late, not early, manifestation of HIV-1 infection Kidney International. 55: 1036-1040. PMID 10027941 DOI: 10.1046/J.1523-1755.1999.0550031036.X  0.521
1998 Singhal PC, Sharma P, Loona R, Gibbons N, Franki N, Klotman PE. Enhanced Proliferation, Apoptosis, and Matrix Accumulation by Mesangial Cells Derived from HIV-1 Transgenic Mice Journal of Investigative Medicine. 46: 297-302. PMID 9737092  0.338
1998 Schwartz EJ, Klotman PE. Pathogenesis of human immunodeficiency virus (HIV)-associated nephropathy. Seminars in Nephrology. 18: 436-45. PMID 9692355  0.438
1998 Winston JA, Burns GC, Klotman PE. The human immunodeficiency virus (HIV) epidemic and HIV-associated nephropathy Seminars in Nephrology. 18: 373-377. PMID 9692350  0.448
1998 Langer JC, Klotman ME, Hanss B, Tulchin N, Bruggeman LA, Klotman PE, Lipkowitz MS. Adeno-associated virus gene transfer into renal cells: Potential for in vivo gene delivery Experimental Nephrology. 6: 189-194. PMID 9639033 DOI: 10.1159/000020522  0.335
1998 Klotman PE, Burns GC, Sivak SL. Early treatment with ACE inhibition may benefit HIV-associated nephropathy patients American Journal of Kidney Diseases. 31: 719-722. PMID 9531193  0.366
1997 Bruggeman LA, Dikman S, Meng C, Quaggin SE, Coffman TM, Klotman PE. Nephropathy in human immunodeficiency virus-1 transgenic mice is due to renal transgene expression Journal of Clinical Investigation. 100: 84-92. PMID 9202060 DOI: 10.1172/Jci119525  0.515
1997 Bodi I, Kimmel PL, Abraham AA, Svetkey LP, Klotman PE, Kopp JB. Renal TGF-β in HIV-associated kidney diseases Kidney International. 51: 1568-1577. PMID 9150474 DOI: 10.1038/Ki.1997.215  0.481
1996 Lipkowitz MS, Klotman ME, Bruggeman LA, Nicklin P, Hanss B, Rappaport J, Klotman PE. Molecular therapy for renal diseases American Journal of Kidney Diseases. 28: 475-492. PMID 8840936 DOI: 10.1016/S0272-6386(96)90457-6  0.338
1996 Winston JA, Klotman PE. Are we missing an epidemic of HIV-associated nephropathy? Journal of the American Society of Nephrology. 7: 1-7. PMID 8808103  0.426
1996 Klotman PE, Notkins AL. Transgenic models of human immunodeficiency virus type-1 Current Topics in Microbiology and Immunology. 206: 197-222. PMID 8608718  0.439
1996 Washburn RG, Nana-Sinkam P, Bruggeman LA, Klotman PE. HIV transgenic mouse model for disseminated cryptococcosis Journal of Investigative Medicine. 44: 321a.  0.392
1995 Rappaport J, Richardson MW, Klotman PE, Arya SK, Baier-Bitterlich G. Inhibition of HIV-1 expression by HIV-2 Journal of Molecular Medicine. 73: 583-589. PMID 8825754 DOI: 10.1007/BF00196351  0.443
1995 Klotman PE, Rappaport J, Ray P, Kopp JB, Franks R, Bruggeman LA, Notkins AL. Transgenic models of HIV-1 Aids. 9: 313-324. PMID 7794536 DOI: 10.1097/00002030-199504000-00001  0.467
1995 Franks RR, Ray PE, Babbott CC, Bryant JL, Notkins AL, Santoro TJ, Klotman PE. Maternal-fetal interactions affect growth of human immunodeficiency virus type 1 transgenic mice. Pediatric Research. 37: 56-63. PMID 7700734  0.349
1995 Rappaport J, Hanss B, Kopp JB, Copeland TD, Bruggeman LA, Coffman TM, Klotman PE. Transport of phosphorothioate oligonucleotides in kidney: Implications for molecular therapy Kidney International. 47: 1462-1469. PMID 7637275 DOI: 10.1038/Ki.1995.205  0.359
1994 Ray PE, McCune BK, Gomez RA, Ruley EJ, Klotman PE. Expression of transforming growth factor β3 in hypertrophic juxtaglomerular apparatus [5] New England Journal of Medicine. 330: 68-69. PMID 8259157 DOI: 10.1056/Nejm199401063300117  0.35
1994 Sei S, Kleiner DE, Kopp JB, Chandra R, Klotman PE, Yarchoan R, Pizzo PA, Mitsuya H. Quantitative analysis of viral burden in tissues from adults and children with symptomatic human immunodeficiency virus type 1 infection assessed by polymerase chain reaction Journal of Infectious Diseases. 170: 325-333. PMID 8035018 DOI: 10.1093/infdis/170.2.325  0.38
1994 Kopp JB, Ray PE, Adler SH, Bruggeman LA, Mangurian CV, Owens JW, Eckhaus MA, Bryant JL, Klotman PE. Nephropathy in HIV-transgenic mice. Contributions to Nephrology. 107: 194-204. PMID 8004968  0.385
1994 Ray PE, Bruggeman LA, Weeks BS, Kopp JB, Bryant JL, Owens JW, Notkins AL, Klotman PE. bFGF and its low affinity receptors in the pathogenesis of HIV-associated nephropathy in transgenic mice. Kidney International. 46: 759-72. PMID 7996798  0.469
1994 Rappaport J, Kopp JB, Klotman PE. Host virus interactions and the molecular regulation of HIV-1: Role in the pathogenesis of HIV-associated nephropathy Kidney International. 46: 16-27. PMID 7933833  0.42
1994 Santoro TJ, Bryant JL, Pellicoro J, Klotman ME, Kopp JB, Bruggeman LA, Franks RR, Notkins AL, Klotman PE. Growth failure and AIDS-like cachexia syndrome in HIV-1 transgenic mice. Virology. 201: 147-51. PMID 7909972 DOI: 10.1006/Viro.1994.1276  0.443
1993 Kopp JB, Rooney JF, Wohlenberg C, Dorfman N, Marinos NJ, Bryant JL, Katz SI, Notkins AL, Klotman PE. Cutaneous disorders and viral gene expression in HIV-1 transgenic mice. Aids Research and Human Retroviruses. 9: 267-75. PMID 8471318 DOI: 10.1089/Aid.1993.9.267  0.484
1993 Weeks BS, Klotman ME, Holloway E, Stetler-Stevenson WG, Kleinman HK, Klotman PE. HIV-1 infection stimulates T cell invasiveness and synthesis of the 92- kDa type IV collagenase Aids Research and Human Retroviruses. 9: 513-518. PMID 8347396 DOI: 10.1089/Aid.1993.9.513  0.484
1993 Dhawan S, Weeks BS, Abbasi F, Gralnick HR, Notkins AL, Klotman ME, Yamada KM, Klotman PE. Increased Expression of α4β1 and α5β1 Integrins on HTLV-I-Infected Lymphocytes Virology. 197: 778-781. PMID 7504369 DOI: 10.1006/Viro.1993.1656  0.302
1992 Kopp JB, Klotman ME, Adler SH, Bruggeman LA, Dickie P, Marinos NJ, Eckhaus M, Bryant JL, Notkins AL, Klotman PE. Progressive glomerulosclerosis and enhanced renal accumulation of basement membrane components in mice transgenic for human immunodeficiency virus type 1 genes. Proceedings of the National Academy of Sciences of the United States of America. 89: 1577-81. PMID 1542649  0.413
1991 Bruggeman LA, Horikoshi S, Burbelo PD, Yamada Y, Klotman PE. Physiology and cell biology update: mechanisms of type IV collagen gene regulation American Journal of Kidney Diseases. 18: 134-139. PMID 2063849 DOI: 10.1016/S0272-6386(12)80305-2  0.341
1991 Weeks BS, Klotman ME, Dhawan S, Kibbey M, Rappaport J, Kleinman HK, Yamada KM, Klotman PE. HIV-1 infection of human T lymphocytes results in enhanced α5β1 integrin expression Journal of Cell Biology. 114: 847-853. PMID 1831204 DOI: 10.1083/jcb.114.4.847  0.333
1989 Coffman TM, Ruiz P, Sanfilippo F, Klotman PE. Chronic thromboxane inhibition preserves function of rejecting rat renal allografts Kidney International. 35: 24-30. PMID 2651752 DOI: 10.1038/Ki.1989.4  0.331
1988 Ruiz P, Coffman TM, Howell DN, Straznickas J, Scroggs MW, Baldwin WM, Klotman PE, Sanfilippo F. Evidence that pretransplant donor blood transfusion prevents rat renal allograft dysfunction but not the in situ cellular alloimmune or morphologic manifestations of rejection Transplantation. 45: 1-7. PMID 3276038 DOI: 10.1097/00007890-198801000-00002  0.351
1988 Coffman TM, Yohay D, Carr DR, Brazy PC, Yarger WE, Klotman PE. Effect of dietary fish oil supplementation on eicosanoid production by rat renal allografts. Transplantation. 45: 470-4. PMID 3125638 DOI: 10.1097/00007890-198802000-00045  0.32
1987 Coffman TM, Carr DR, Yarger WE, Klotman PE. Evidence that renal prostaglandin and thromboxane production is stimulated in chronic cyclosporine nephrotoxicity Transplantation. 43: 282-285. PMID 3810836 DOI: 10.1097/00007890-198702000-00023  0.349
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