| Year |
Citation |
Score |
| 2022 |
Kim AY, Duerr FM, Phillips JN, Samulski RJ, Grieger JC, Goodrich LR. Serotype-specific transduction of canine joint tissue explants and cultured monolayers by self-complementary adeno-associated viral vectors. Gene Therapy. PMID 36261499 DOI: 10.1038/s41434-022-00366-x |
0.765 |
|
| 2022 |
Pupo A, Fernández A, Low SH, François A, Suárez-Amarán L, Samulski RJ. AAV Vectors: The Rubik's Cube of Human Gene Therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 36203359 DOI: 10.1016/j.ymthe.2022.09.015 |
0.414 |
|
| 2021 |
Zhang J, Yu X, Guo P, Firrman J, Pouchnik D, Diao Y, Samulski RJ, Xiao W. Satellite Subgenomic Particles Are Key Regulators of Adeno-Associated Virus Life Cycle. Viruses. 13. PMID 34205760 DOI: 10.3390/v13061185 |
0.348 |
|
| 2020 |
Powell SK, Samulski RJ, McCown TJ. AAV Capsid-Promoter Interactions Determine CNS Cell-Selective Gene Expression In Vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32213322 DOI: 10.1016/j.ymthe.2020.03.007 |
0.332 |
|
| 2020 |
Li C, Samulski RJ. Engineering adeno-associated virus vectors for gene therapy. Nature Reviews. Genetics. PMID 32042148 DOI: 10.1038/s41576-019-0205-4 |
0.389 |
|
| 2020 |
Earley LF, Conatser L, Lue VM, Dobbins AL, Li C, Hirsch M, Samulski RJ. Adeno-associated virus serotype specific inverted terminal repeat sequence role in vector transgene expression. Human Gene Therapy. PMID 31914802 DOI: 10.1089/hum.2019.274 |
0.344 |
|
| 2020 |
Pei X, Shao W, Xing A, Askew C, Chen X, Cui C, Abajas YL, Gerber DA, Merricks EP, Nichols TC, Li W, Samulski RJ, Li C. Development of AAV Variants with Human Hepatocyte Tropism and Neutralizing Antibody Escape Capacity Molecular Therapy - Methods & Clinical Development. 18: 259-268. DOI: 10.1016/j.omtm.2020.06.003 |
0.732 |
|
| 2019 |
Pei X, Earley LF, He Y, Chen X, Hall NE, Samulski RJ, Li C. Corrigendum: Efficient Capsid Antigen Presentation From Adeno-Associated Virus Empty Virions . Frontiers in Immunology. 10: 3076. PMID 32117195 DOI: 10.3389/Fimmu.2019.03076 |
0.415 |
|
| 2019 |
Chai Z, Zhang X, Dobbins AL, Frost EA, Samulski RJ, Li C. Chimeric Capsid Proteins Impact Transduction Efficiency of Haploid Adeno-Associated Virus Vectors. Viruses. 11. PMID 31835440 DOI: 10.3390/v11121138 |
0.412 |
|
| 2019 |
Shao W, Pei X, Cui C, Askew C, Dobbins A, Chen X, Abajas YL, Gerber DA, Samulski RJ, Nichols TC, Li C. Superior human hepatocyte transduction with adeno-associated virus vector serotype 7. Gene Therapy. PMID 31570819 DOI: 10.1038/S41434-019-0104-5 |
0.778 |
|
| 2019 |
Chai Z, Zhang X, Dobbins AL, Rigsbee KM, Wang B, Samulski RJ, Li C. Optimization of Dexamethasone Administration for Maintaining Global Transduction Efficacy of Adeno-Associated Virus 9. Human Gene Therapy. PMID 30700148 DOI: 10.1089/Hum.2018.233 |
0.448 |
|
| 2019 |
Rabinowitz J, Chan YK, Samulski RJ. Adeno-associated Virus (AAV) versus Immune Response. Viruses. 11. PMID 30691064 DOI: 10.3390/V11020102 |
0.39 |
|
| 2018 |
Tan YZ, Aiyer S, Mietzsch M, Hull JA, McKenna R, Grieger J, Samulski RJ, Baker TS, Agbandje-McKenna M, Lyumkis D. Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant. Nature Communications. 9: 3628. PMID 30194371 DOI: 10.1038/S41467-018-06076-6 |
0.744 |
|
| 2018 |
Chai Z, Samulski RJ, Li C. Nab Escaping AAV Mutants Isolated from Mouse Muscles. Bio-Protocol. 8. PMID 29951572 DOI: 10.21769/BioProtoc.2841 |
0.331 |
|
| 2018 |
Xiao W, Gao G, Ling C, Herzog RW, Xiao X, Samulski RJ. Impact of neutralizing antibodies against AAV is a key consideration in gene transfer to nonhuman primates. Nature Medicine. PMID 29867233 DOI: 10.1038/S41591-018-0062-2 |
0.346 |
|
| 2018 |
Pei X, Earley LF, He Y, Chen X, Hall NE, Samulski RJ, Li C. Efficient Capsid Antigen Presentation From Adeno-Associated Virus Empty Virions . Frontiers in Immunology. 9: 844. PMID 29725339 DOI: 10.3389/Fimmu.2018.00844 |
0.43 |
|
| 2018 |
Bennett AD, Wong K, Lewis J, Tseng YS, Smith JK, Chipman P, McKenna R, Samulski RJ, Kleinschmidt J, Agbandje-McKenna M. AAV6 K531 serves a dual function in selective receptor and antibody ADK6 recognition. Virology. 518: 369-376. PMID 29604478 DOI: 10.1016/J.Virol.2018.03.007 |
0.322 |
|
| 2018 |
Samulski RJ, Smith JM, Grieger JC, Cornetta K, Snyder R. The Growing Promise of Gene Therapy Approaches Cell and Gene Therapy Insights. 4: 1043-1049. DOI: 10.18609/cgti.2018.104 |
0.726 |
|
| 2017 |
Shao W, Chen X, Samulski RJ, Hirsch ML, Li C. Inhibition of antigen presentation during AAV gene therapy using virus peptides. Human Molecular Genetics. PMID 29272432 DOI: 10.1093/Hmg/Ddx427 |
0.486 |
|
| 2017 |
Sun J, Hua B, Samulski RJ, Li C. Gene delivery of activated Factor VII Using Alternative AAV Serotype Improves Hemostasis in Hemophiliac Mice with FVIII Inhibitors and AAV Neutralizing antibodies. Human Gene Therapy. PMID 28478688 DOI: 10.1089/Hum.2017.016 |
0.37 |
|
| 2017 |
Tarantal AF, Lee CC, Martinez ML, Aravind A, Samulski RJ. Systemic and Persistent Muscle Gene Expression in Rhesus Monkeys with a Liver De-targeted Adeno-Associated Virus (AAV) Vector. Human Gene Therapy. PMID 28125921 DOI: 10.1089/Hum.2016.130 |
0.347 |
|
| 2016 |
Wang M, Sun J, Crosby A, Woodard K, Hirsch ML, Samulski RJ, Li C. Direct interaction of human serum proteins with AAV virions to enhance AAV transduction: Immediate impact on clinical applications. Gene Therapy. PMID 27834949 DOI: 10.1038/Gt.2016.75 |
0.486 |
|
| 2016 |
Powell SK, Khan N, Parker CL, Samulski RJ, Matsushima G, Gray SJ, McCown TJ. Characterization of a novel adeno-associated viral vector with preferential oligodendrocyte tropism. Gene Therapy. PMID 27628693 DOI: 10.1038/Gt.2016.62 |
0.497 |
|
| 2016 |
Xiao PJ, Mitchell AM, Huang L, Li C, Samulski RJ. Disruption of Microtubules post Virus Entry Enhances Adeno-Associated Virus Vector Transduction. Human Gene Therapy. PMID 26942476 DOI: 10.1089/Hum.2016.008 |
0.624 |
|
| 2016 |
Vance M, Llanga T, Bennett W, Woodard K, Murlidharan G, Chungfat N, Asokan A, Gilger B, Kurtzberg J, Samulski RJ, Hirsch ML. AAV Gene Therapy for MPS1-associated Corneal Blindness. Scientific Reports. 6: 22131. PMID 26899286 DOI: 10.1038/Srep22131 |
0.328 |
|
| 2016 |
Wang G, Evans CH, Benson JM, Hutt JA, Seagrave J, Wilder JA, Grieger JC, Samulski RJ, Terse PS. Safety and biodistribution assessment of sc-rAAV2.5IL-1Ra administered via intra-articular injection in a mono-iodoacetate-induced osteoarthritis rat model. Molecular Therapy. Methods & Clinical Development. 3: 15052. PMID 26817025 DOI: 10.1038/Mtm.2015.52 |
0.727 |
|
| 2016 |
Vance M, Llanga L, Kurtzberg J, Samulski RJ, Hirsch M. 93. Development of AAVidua Vector for the Treatment of Cornea Associated Vision Loss in Bone Marrow Treated-Hurler Patients Molecular Therapy. 24: S40-S41. DOI: 10.1016/S1525-0016(16)32902-1 |
0.393 |
|
| 2016 |
Hemphill DD, McIlwraith CW, Slayden RA, Samulski RJ, Goodrich LR. Adeno-associated virus gene therapy vector scAAVIGF-I for transduction of equine articular chondrocytes and RNA-seq analysis Osteoarthritis and Cartilage. 24: 902-911. DOI: 10.1016/J.Joca.2015.12.001 |
0.425 |
|
| 2015 |
Hastie E, Samulski RJ. Recombinant adeno-associated virus vectors in the treatment of rare diseases. Expert Opinion On Orphan Drugs. 3: 675-689. PMID 27668135 DOI: 10.1517/21678707.2015.1039511 |
0.35 |
|
| 2015 |
Ling C, Wang Y, Lu Y, Wang L, Jayandharan GR, Aslanidi GV, Li B, Cheng B, Ma W, Lentz T, Ling C, Xiao X, Samulski RJ, Muzyczka N, Srivastava A. The Adeno-Associated Virus Genome Packaging Puzzle. Journal of Molecular and Genetic Medicine : An International Journal of Biomedical Research. 9. PMID 26949410 DOI: 10.4172/1747-0862.1000175 |
0.507 |
|
| 2015 |
Grieger JC, Soltys SM, Samulski RJ. Production of Recombinant Adeno-associated Virus Vectors Using Suspension HEK293 Cells and Continuous Harvest of Vector From the Culture Media for GMP FIX and FLT1 Clinical Vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26437810 DOI: 10.1038/Mt.2015.187 |
0.785 |
|
| 2015 |
Salganik M, Hirsch ML, Samulski RJ. Adeno-associated Virus as a Mammalian DNA Vector. Microbiology Spectrum. 3. PMID 26350320 DOI: 10.1128/Microbiolspec.Mdna3-0052-2014 |
0.832 |
|
| 2015 |
Wang M, Crosby A, Hastie E, Samulski JJ, McPhee S, Joshua G, Samulski RJ, Li C. Prediction of adeno-associated virus neutralizing antibody activity for clinical application. Gene Therapy. PMID 26125606 DOI: 10.1038/Gt.2015.69 |
0.435 |
|
| 2015 |
Goodrich LR, Grieger JC, Phillips JN, Khan N, Gray SJ, McIlwraith CW, Samulski RJ. scAAVIL-1ra dosing trial in a large animal model and validation of long-term expression with repeat administration for osteoarthritis therapy. Gene Therapy. 22: 536-45. PMID 25902762 DOI: 10.1038/Gt.2015.21 |
0.757 |
|
| 2015 |
Hastie E, Samulski RJ. Adeno-associated virus at 50: a golden anniversary of discovery, research, and gene therapy success--a personal perspective. Human Gene Therapy. 26: 257-65. PMID 25807962 DOI: 10.1089/Hum.2015.025 |
0.484 |
|
| 2015 |
Monahan PE, Sun J, Gui T, Hu G, Hannah WB, Wichlan DG, Wu Z, Grieger JC, Li C, Suwanmanee T, Stafford DW, Booth CJ, Samulski JJ, Kafri T, McPhee SW, ... Samulski RJ, et al. Employing a gain-of-function factor IX variant R338L to advance the efficacy and safety of hemophilia B human gene therapy: preclinical evaluation supporting an ongoing adeno-associated virus clinical trial. Human Gene Therapy. 26: 69-81. PMID 25419787 DOI: 10.1089/Hum.2014.106 |
0.783 |
|
| 2015 |
Johnson-Kerner BL, Ahmad FS, Diaz AG, Greene JP, Gray SJ, Samulski RJ, Chung WK, Van Coster R, Maertens P, Noggle SA, Henderson CE, Wichterle H. Intermediate filament protein accumulation in motor neurons derived from giant axonal neuropathy iPSCs rescued by restoration of gigaxonin. Human Molecular Genetics. 24: 1420-31. PMID 25398950 DOI: 10.1093/Hmg/Ddu556 |
0.356 |
|
| 2015 |
Ling C, Wang Y, Lu Y, Wang L, Jayandharan GR, Aslanidi GV, Li B, Cheng B, Ma W, Lentz T, Ling C, Xiao X, Samulski RJ, Muzyczka N, Srivastava A. Enhanced transgene expression from recombinant single-stranded D-sequence-substituted adeno-associated virus vectors in human cell lines in vitro and in murine hepatocytes in vivo. Journal of Virology. 89: 952-61. PMID 25355884 DOI: 10.1128/Jvi.02581-14 |
0.62 |
|
| 2015 |
Lentz TB, Samulski RJ. Insight into the mechanism of inhibition of adeno-associated virus by the Mre11/Rad50/Nbs1 complex. Journal of Virology. 89: 181-94. PMID 25320294 DOI: 10.1128/Jvi.01990-14 |
0.332 |
|
| 2015 |
Liang KJ, Samulski RJ. Viral vectors for gene delivery Advances and Challenges in the Delivery of Nucleic Acid Therapeutics. 1: 49-69. DOI: 10.4155/fseb2013.14.165 |
0.379 |
|
| 2015 |
Vance MA, Hirsch M, Samulski RJ, Kurtzberg J, Goodrich L, Telmo L. AAV Gene Therapy for MPS1 Corneal Clouding and Joint Stiffness Blood. 126: 2041-2041. DOI: 10.1182/Blood.V126.23.2041.2041 |
0.411 |
|
| 2014 |
Samulski RJ, Muzyczka N. AAV-Mediated Gene Therapy for Research and Therapeutic Purposes. Annual Review of Virology. 1: 427-51. PMID 26958729 DOI: 10.1146/Annurev-Virology-031413-085355 |
0.638 |
|
| 2014 |
Murlidharan G, Samulski RJ, Asokan A. Biology of adeno-associated viral vectors in the central nervous system. Frontiers in Molecular Neuroscience. 7: 76. PMID 25285067 DOI: 10.3389/Fnmol.2014.00076 |
0.444 |
|
| 2014 |
Pleticha J, Heilmann LF, Evans CH, Asokan A, Samulski RJ, Beutler AS. Preclinical toxicity evaluation of AAV for pain: evidence from human AAV studies and from the pharmacology of analgesic drugs. Molecular Pain. 10: 54. PMID 25183392 DOI: 10.1186/1744-8069-10-54 |
0.387 |
|
| 2014 |
Weinberg MS, Nicolson S, Bhatt AP, McLendon M, Li C, Samulski RJ. Recombinant adeno-associated virus utilizes cell-specific infectious entry mechanisms. Journal of Virology. 88: 12472-84. PMID 25142580 DOI: 10.1128/Jvi.01971-14 |
0.457 |
|
| 2014 |
Hemphill DD, McIlwraith CW, Samulski RJ, Goodrich LR. Adeno-associated viral vectors show serotype specific transduction of equine joint tissue explants and cultured monolayers. Scientific Reports. 4: 5861. PMID 25069854 DOI: 10.1038/srep05861 |
0.3 |
|
| 2014 |
Ishikawa K, Fish KM, Tilemann L, Rapti K, Aguero J, Santos-Gallego CG, Lee A, Karakikes I, Xie C, Akar FG, Shimada YJ, Gwathmey JK, Asokan A, McPhee S, Samulski J, ... Samulski RJ, et al. Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 2038-45. PMID 25023328 DOI: 10.1038/Mt.2014.127 |
0.314 |
|
| 2014 |
Bartlett JS, Samulski RJ. Methods for the construction and propagation of recombinant adeno-associated virus vectors. Methods in Molecular Medicine. 7: 25-40. PMID 24493416 DOI: 10.1385/0-89603-484-4:25 |
0.529 |
|
| 2014 |
Mitchell AM, Hirsch ML, Li C, Samulski RJ. Promyelocytic leukemia protein is a cell-intrinsic factor inhibiting parvovirus DNA replication. Journal of Virology. 88: 925-36. PMID 24198403 DOI: 10.1128/Jvi.02922-13 |
0.459 |
|
| 2014 |
Qiao C, Li C, Zhao C, Li J, Bian T, Grieger J, Li J, Samulski RJ, Xiao X. K137R mutation on adeno-associated viral capsids had minimal effect on enhancing gene delivery in vivo. Human Gene Therapy Methods. 25: 33-9. PMID 24116972 DOI: 10.1089/Hgtb.2013.176 |
0.784 |
|
| 2013 |
Dismuke DJ, Tenenbaum L, Samulski RJ. Biosafety of recombinant adeno-associated virus vectors. Current Gene Therapy. 13: 434-52. PMID 24195602 DOI: 10.2174/15665232113136660007 |
0.418 |
|
| 2013 |
Asokan A, Samulski RJ. An emerging adeno-associated viral vector pipeline for cardiac gene therapy. Human Gene Therapy. 24: 906-13. PMID 24164238 DOI: 10.1089/Hum.2013.2515 |
0.325 |
|
| 2013 |
Shen S, Horowitz ED, Troupes AN, Brown SM, Pulicherla N, Samulski RJ, Agbandje-McKenna M, Asokan A. Engraftment of a galactose receptor footprint onto adeno-associated viral capsids improves transduction efficiency. The Journal of Biological Chemistry. 288: 28814-23. PMID 23940044 DOI: 10.1074/Jbc.M113.482380 |
0.41 |
|
| 2013 |
Hirsch ML, Li C, Bellon I, Yin C, Chavala S, Pryadkina M, Richard I, Samulski RJ. Oversized AAV transductifon is mediated via a DNA-PKcs-independent, Rad51C-dependent repair pathway. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2205-16. PMID 23939025 DOI: 10.1038/Mt.2013.184 |
0.447 |
|
| 2013 |
Redmond DE, McEntire CR, Kingsbery JP, Leranth C, Elsworth JD, Bjugstad KB, Roth RH, Samulski RJ, Sladek JR. Comparison of fetal mesencephalic grafts, AAV-delivered GDNF, and both combined in an MPTP-induced nonhuman primate Parkinson's model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2160-8. PMID 23913185 DOI: 10.1038/Mt.2013.180 |
0.327 |
|
| 2013 |
Gurda BL, DiMattia MA, Miller EB, Bennett A, McKenna R, Weichert WS, Nelson CD, Chen WJ, Muzyczka N, Olson NH, Sinkovits RS, Chiorini JA, Zolotutkhin S, Kozyreva OG, Samulski RJ, et al. Capsid antibodies to different adeno-associated virus serotypes bind common regions. Journal of Virology. 87: 9111-24. PMID 23760240 DOI: 10.1128/Jvi.00622-13 |
0.638 |
|
| 2013 |
Lompré AM, Hadri L, Merlet E, Keuylian Z, Mougenot N, Karakikes I, Chen J, Atassi F, Marchand A, Blaise R, Limon I, McPhee SW, Samulski RJ, Hajjar RJ, Lipskaia L. Efficient transduction of vascular smooth muscle cells with a translational AAV2.5 vector: a new perspective for in-stent restenosis gene therapy. Gene Therapy. 20: 901-12. PMID 23535897 DOI: 10.1038/Gt.2013.13 |
0.4 |
|
| 2013 |
He Y, Weinberg MS, Hirsch M, Johnson MC, Tisch R, Samulski RJ, Li C. Kinetics of adeno-associated virus serotype 2 (AAV2) and AAV8 capsid antigen presentation in vivo are identical. Human Gene Therapy. 24: 545-53. PMID 23534873 DOI: 10.1089/Hum.2013.065 |
0.361 |
|
| 2013 |
Li C, He Y, Nicolson S, Hirsch M, Weinberg MS, Zhang P, Kafri T, Samulski RJ. Adeno-associated virus capsid antigen presentation is dependent on endosomal escape. The Journal of Clinical Investigation. 123: 1390-401. PMID 23454772 DOI: 10.1172/Jci66611 |
0.345 |
|
| 2013 |
Venkatakrishnan B, Yarbrough J, Domsic J, Bennett A, Bothner B, Kozyreva OG, Samulski RJ, Muzyczka N, McKenna R, Agbandje-McKenna M. Structure and dynamics of adeno-associated virus serotype 1 VP1-unique N-terminal domain and its role in capsid trafficking. Journal of Virology. 87: 4974-84. PMID 23427155 DOI: 10.1128/Jvi.02524-12 |
0.612 |
|
| 2013 |
Mitchell AM, Li C, Samulski RJ. Arsenic trioxide stabilizes accumulations of adeno-associated virus virions at the perinuclear region, increasing transduction in vitro and in vivo. Journal of Virology. 87: 4571-83. PMID 23408604 DOI: 10.1128/Jvi.03443-12 |
0.397 |
|
| 2013 |
Goodrich LR, Phillips JN, McIlwraith CW, Foti SB, Grieger JC, Gray SJ, Samulski RJ. Optimization of scAAVIL-1ra In Vitro and In Vivo to Deliver High Levels of Therapeutic Protein for Treatment of Osteoarthritis. Molecular Therapy. Nucleic Acids. 2: e70. PMID 23385523 DOI: 10.1038/Mtna.2012.61 |
0.743 |
|
| 2013 |
Mussche S, Devreese B, Nagabhushan Kalburgi S, Bachaboina L, Fox JC, Shih HJ, Van Coster R, Samulski RJ, Gray SJ. Restoration of cytoskeleton homeostasis after gigaxonin gene transfer for giant axonal neuropathy. Human Gene Therapy. 24: 209-19. PMID 23316953 DOI: 10.1089/Hum.2012.107 |
0.326 |
|
| 2013 |
Weinberg MS, Samulski RJ, McCown TJ. Adeno-associated virus (AAV) gene therapy for neurological disease. Neuropharmacology. 69: 82-8. PMID 22465202 DOI: 10.1016/j.neuropharm.2012.03.004 |
0.369 |
|
| 2013 |
Ferreira JR, Hirsch ML, Zhang L, Park Y, Samulski RJ, Hu WS, Ko CC. Three-dimensional multipotent progenitor cell aggregates for expansion, osteogenic differentiation and 'in vivo' tracing with AAV vector serotype 6. Gene Therapy. 20: 158-68. PMID 22402320 DOI: 10.1038/Gt.2012.16 |
0.304 |
|
| 2013 |
Ellis BL, Hirsch ML, Porter SN, Samulski RJ, Porteus MH. Zinc-finger nuclease-mediated gene correction using single AAV vector transduction and enhancement by Food and Drug Administration-approved drugs. Gene Therapy. 20: 35-42. PMID 22257934 DOI: 10.1038/Gt.2011.211 |
0.477 |
|
| 2012 |
Xiao PJ, Lentz TB, Samulski RJ. Recombinant adeno-associated virus: clinical application and development as a gene-therapy vector. Therapeutic Delivery. 3: 835-56. PMID 22900466 DOI: 10.4155/Tde.12.63 |
0.653 |
|
| 2012 |
Xiao PJ, Samulski RJ. Cytoplasmic trafficking, endosomal escape, and perinuclear accumulation of adeno-associated virus type 2 particles are facilitated by microtubule network. Journal of Virology. 86: 10462-73. PMID 22811523 DOI: 10.1128/Jvi.00935-12 |
0.646 |
|
| 2012 |
Li C, Diprimio N, Bowles DE, Hirsch ML, Monahan PE, Asokan A, Rabinowitz J, Agbandje-McKenna M, Samulski RJ. Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles. Journal of Virology. 86: 7752-9. PMID 22593151 DOI: 10.1128/Jvi.00675-12 |
0.81 |
|
| 2012 |
Denard J, Beley C, Kotin R, Lai-Kuen R, Blot S, Leh H, Asokan A, Samulski RJ, Moullier P, Voit T, Garcia L, Svinartchouk F. Human galectin 3 binding protein interacts with recombinant adeno-associated virus type 6. Journal of Virology. 86: 6620-31. PMID 22496229 DOI: 10.1128/Jvi.00297-12 |
0.407 |
|
| 2012 |
Grieger JC, Samulski RJ. Adeno-associated virus vectorology, manufacturing, and clinical applications. Methods in Enzymology. 507: 229-54. PMID 22365777 DOI: 10.1016/B978-0-12-386509-0.00012-0 |
0.79 |
|
| 2012 |
Asokan A, Schaffer DV, Samulski RJ. The AAV vector toolkit: poised at the clinical crossroads. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 699-708. PMID 22273577 DOI: 10.1038/Mt.2011.287 |
0.365 |
|
| 2012 |
Xiao PJ, Li C, Neumann A, Samulski RJ. Quantitative 3D tracing of gene-delivery viral vectors in human cells and animal tissues. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 317-28. PMID 22108857 DOI: 10.1038/mt.2011.250 |
0.627 |
|
| 2012 |
Bowles DE, McPhee SW, Li C, Gray SJ, Samulski JJ, Camp AS, Li J, Wang B, Monahan PE, Rabinowitz JE, Grieger JC, Govindasamy L, Agbandje-McKenna M, Xiao X, Samulski RJ. Phase 1 gene therapy for Duchenne muscular dystrophy using a translational optimized AAV vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 443-55. PMID 22068425 DOI: 10.1038/Mt.2011.237 |
0.796 |
|
| 2012 |
Lentz TB, Gray SJ, Samulski RJ. Viral vectors for gene delivery to the central nervous system. Neurobiology of Disease. 48: 179-88. PMID 22001604 DOI: 10.1016/J.Nbd.2011.09.014 |
0.411 |
|
| 2012 |
Federici T, Taub JS, Baum GR, Gray SJ, Grieger JC, Matthews KA, Handy CR, Passini MA, Samulski RJ, Boulis NM. Robust spinal motor neuron transduction following intrathecal delivery of AAV9 in pigs. Gene Therapy. 19: 852-9. PMID 21918551 DOI: 10.1038/Gt.2011.130 |
0.76 |
|
| 2012 |
Li C, Narkbunnam N, Samulski RJ, Asokan A, Hu G, Jacobson LJ, Manco-Johnson MJ, Monahan PE. Neutralizing antibodies against adeno-associated virus examined prospectively in pediatric patients with hemophilia. Gene Therapy. 19: 288-94. PMID 21697954 DOI: 10.1038/Gt.2011.90 |
0.481 |
|
| 2011 |
Lai CM, Estcourt MJ, Himbeck RP, Lee SY, Yew-San Yeo I, Luu C, Loh BK, Lee MW, Barathi A, Villano J, Ang CL, van der Most RG, Constable IJ, Dismuke D, Samulski RJ, et al. Preclinical safety evaluation of subretinal AAV2.sFlt-1 in non-human primates. Gene Therapy. 19: 999-1009. PMID 22071974 DOI: 10.1038/Gt.2011.169 |
0.361 |
|
| 2011 |
Gray SJ, Choi VW, Asokan A, Haberman RA, McCown TJ, Samulski RJ. Production of recombinant adeno-associated viral vectors and use in in vitro and in vivo administration. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 4.17. PMID 21971848 DOI: 10.1002/0471142301.Ns0417S57 |
0.537 |
|
| 2011 |
Li C, Xiao P, Gray SJ, Weinberg MS, Samulski RJ. Combination therapy utilizing shRNA knockdown and an optimized resistant transgene for rescue of diseases caused by misfolded proteins. Proceedings of the National Academy of Sciences of the United States of America. 108: 14258-63. PMID 21844342 DOI: 10.1073/Pnas.1109522108 |
0.312 |
|
| 2011 |
Weinberg MS, Blake BL, Samulski RJ, McCown TJ. The influence of epileptic neuropathology and prior peripheral immunity on CNS transduction by rAAV2 and rAAV5. Gene Therapy. 18: 961-8. PMID 21490684 DOI: 10.1038/Gt.2011.49 |
0.404 |
|
| 2011 |
Phillips JL, Hegge J, Wolff JA, Samulski RJ, Asokan A. Systemic gene transfer to skeletal muscle using reengineered AAV vectors. Methods in Molecular Biology (Clifton, N.J.). 709: 141-51. PMID 21194026 DOI: 10.1007/978-1-61737-982-6_9 |
0.311 |
|
| 2011 |
Monahan PE, Sun J, Gui T, Wichlan DG, McPhee SW, Samulski RJ. Employing Factor IX Variants to Avoid Limitations Imposed by Immune Recognition of AAV Vector in Hemophilia B Gene Therapy Blood. 118: 3124-3124. DOI: 10.1182/blood.v118.21.3124.3124 |
0.364 |
|
| 2010 |
Gray SJ, Woodard KT, Samulski RJ. Viral vectors and delivery strategies for CNS gene therapy. Therapeutic Delivery. 1: 517-34. PMID 22833965 DOI: 10.4155/Tde.10.50 |
0.399 |
|
| 2010 |
DiPrimio N, McPhee SW, Samulski RJ. Adeno-associated virus for the treatment of muscle diseases: toward clinical trials. Current Opinion in Molecular Therapeutics. 12: 553-60. PMID 20886387 |
0.796 |
|
| 2010 |
Mitchell AM, Nicolson SC, Warischalk JK, Samulski RJ. AAV's anatomy: roadmap for optimizing vectors for translational success. Current Gene Therapy. 10: 319-40. PMID 20712583 DOI: 10.2174/156652310793180706 |
0.392 |
|
| 2010 |
Monahan PE, Lothrop CD, Sun J, Hirsch ML, Kafri T, Kantor B, Sarkar R, Tillson DM, Elia JR, Samulski RJ. Proteasome inhibitors enhance gene delivery by AAV virus vectors expressing large genomes in hemophilia mouse and dog models: a strategy for broad clinical application. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1907-16. PMID 20700109 DOI: 10.1038/Mt.2010.170 |
0.412 |
|
| 2010 |
Johnson JS, Li C, DiPrimio N, Weinberg MS, McCown TJ, Samulski RJ. Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction. Journal of Virology. 84: 8888-902. PMID 20573820 DOI: 10.1128/Jvi.00687-10 |
0.797 |
|
| 2010 |
Hollis ER, Jamshidi P, Lorenzana AO, Lee JK, Gray SJ, Samulski RJ, Zheng B, Tuszynski MH. Transient demyelination increases the efficiency of retrograde AAV transduction. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1496-500. PMID 20502445 DOI: 10.1038/Mt.2010.97 |
0.328 |
|
| 2010 |
Hirsch ML, Green L, Porteus MH, Samulski RJ. Self-complementary AAV mediates gene targeting and enhances endonuclease delivery for double-strand break repair. Gene Therapy. 17: 1175-80. PMID 20463753 DOI: 10.1038/Gt.2010.65 |
0.448 |
|
| 2010 |
Hewitt FC, Samulski RJ. Creating a novel origin of replication through modulating DNA-protein interfaces. Plos One. 5: e8850. PMID 20107513 DOI: 10.1371/journal.pone.0008850 |
0.754 |
|
| 2010 |
Hirsch ML, Agbandje-McKenna M, Samulski RJ. Little vector, big gene transduction: fragmented genome reassembly of adeno-associated virus. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 6-8. PMID 20048740 DOI: 10.1038/Mt.2009.280 |
0.453 |
|
| 2010 |
Asokan A, Conway JC, Phillips JL, Li C, Hegge J, Sinnott R, Yadav S, DiPrimio N, Nam HJ, Agbandje-McKenna M, McPhee S, Wolff J, Samulski RJ. Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle. Nature Biotechnology. 28: 79-82. PMID 20037580 DOI: 10.1038/Nbt.1599 |
0.811 |
|
| 2010 |
Markakis EA, Vives KP, Bober J, Leichtle S, Leranth C, Beecham J, Elsworth JD, Roth RH, Samulski RJ, Redmond DE. Comparative transduction efficiency of AAV vector serotypes 1-6 in the substantia nigra and striatum of the primate brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 588-93. PMID 20010918 DOI: 10.1038/Mt.2009.286 |
0.343 |
|
| 2010 |
Buie LK, Rasmussen CA, Porterfield EC, Ramgolam VS, Choi VW, Markovic-Plese S, Samulski RJ, Kaufman PL, Borrás T. Self-complementary AAV virus (scAAV) safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys. Investigative Ophthalmology & Visual Science. 51: 236-48. PMID 19684004 DOI: 10.1167/Iovs.09-3847 |
0.409 |
|
| 2010 |
Li C, Hirsch ML, Samulski RJ. Development of AAV vectors for the therapy of autoimmune and inflammatory diseases Milestones in Drug Therapy. 161-180. |
0.371 |
|
| 2009 |
Foti SB, Samulski RJ, McCown TJ. Delivering multiple gene products in the brain from a single adeno-associated virus vector. Gene Therapy. 16: 1314-9. PMID 19727140 DOI: 10.1038/Gt.2009.106 |
0.51 |
|
| 2009 |
Goodrich LR, Choi VW, Carbone BA, McIlwraith CW, Samulski RJ. Ex vivo serotype-specific transduction of equine joint tissue by self-complementary adeno-associated viral vectors. Human Gene Therapy. 20: 1697-702. PMID 19642864 DOI: 10.1089/Hum.2009.030 |
0.413 |
|
| 2009 |
Li W, Zhang L, Johnson JS, Zhijian W, Grieger JC, Ping-Jie X, Drouin LM, Agbandje-McKenna M, Pickles RJ, Samulski RJ. Generation of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2067-77. PMID 19603002 DOI: 10.1038/Mt.2009.155 |
0.767 |
|
| 2009 |
McPhee SWJ, Samulski RJ. Gene therapy for cardiomyocytes, a heart beat away Gene Therapy. 16: 707-708. PMID 19404321 DOI: 10.1038/Gt.2009.40 |
0.389 |
|
| 2009 |
Li C, Hirsch M, DiPrimio N, Asokan A, Goudy K, Tisch R, Samulski RJ. Cytotoxic-T-lymphocyte-mediated elimination of target cells transduced with engineered adeno-associated virus type 2 vector in vivo. Journal of Virology. 83: 6817-24. PMID 19369348 DOI: 10.1128/Jvi.00278-09 |
0.798 |
|
| 2009 |
Hewitt FC, Li C, Gray SJ, Cockrell S, Washburn M, Samulski RJ. Reducing the risk of adeno-associated virus (AAV) vector mobilization with AAV type 5 vectors. Journal of Virology. 83: 3919-29. PMID 19211760 DOI: 10.1128/Jvi.02466-08 |
0.789 |
|
| 2009 |
Johnson JS, Samulski RJ. Enhancement of adeno-associated virus infection by mobilizing capsids into and out of the nucleolus. Journal of Virology. 83: 2632-44. PMID 19109385 DOI: 10.1128/Jvi.02309-08 |
0.321 |
|
| 2009 |
Li C, Hirsch M, Carter P, Asokan A, Zhou X, Wu Z, Samulski RJ. A small regulatory element from chromosome 19 enhances liver-specific gene expression. Gene Therapy. 16: 43-51. PMID 18701910 DOI: 10.1038/Gt.2008.134 |
0.422 |
|
| 2008 |
Hollis Ii ER, Kadoya K, Hirsch M, Samulski RJ, Tuszynski MH. Efficient Retrograde Neuronal Transduction Utilizing Self-complementary AAV1. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 296-301. PMID 28178539 DOI: 10.1038/Sj.Mt.6300367 |
0.371 |
|
| 2008 |
Li W, Asokan A, Wu Z, Van Dyke T, DiPrimio N, Johnson JS, Govindaswamy L, Agbandje-McKenna M, Leichtle S, Eugene Redmond D, McCown TJ, Petermann KB, Sharpless NE, Samulski RJ. Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1252-1260. PMID 28178482 DOI: 10.1038/Mt.2008.100 |
0.827 |
|
| 2008 |
Asokan A, Johnson JS, Li C, Samulski RJ. Bioluminescent virion shells: new tools for quantitation of AAV vector dynamics in cells and live animals. Gene Therapy. 15: 1618-22. PMID 18668144 DOI: 10.1038/Gt.2008.127 |
0.457 |
|
| 2008 |
Gray SJ, Samulski RJ. Optimizing gene delivery vectors for the treatment of heart disease. Expert Opinion On Biological Therapy. 8: 911-22. PMID 18549322 DOI: 10.1517/14712598.8.7.911 |
0.366 |
|
| 2008 |
Li W, Asokan A, Wu Z, Van Dyke T, DiPrimio N, Johnson JS, Govindaswamy L, Agbandje-McKenna M, Leichtle S, Redmond DE, McCown TJ, Petermann KB, Sharpless NE, Samulski RJ. Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1252-60. PMID 18500254 DOI: 10.1038/mt.2008.100 |
0.82 |
|
| 2008 |
DiPrimio N, Asokan A, Govindasamy L, Agbandje-McKenna M, Samulski RJ. Surface loop dynamics in adeno-associated virus capsid assembly. Journal of Virology. 82: 5178-89. PMID 18367523 DOI: 10.1128/Jvi.02721-07 |
0.79 |
|
| 2008 |
Zhou X, Zeng X, Fan Z, Li C, McCown T, Samulski RJ, Xiao X. Adeno-associated virus of a single-polarity DNA genome is capable of transduction in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 494-9. PMID 18180769 DOI: 10.1038/Sj.Mt.6300397 |
0.39 |
|
| 2008 |
Zhong L, Zhou X, Li Y, Qing K, Xiao X, Samulski RJ, Srivastava A. Single-polarity recombinant adeno-associated virus 2 vector-mediated transgene expression in vitro and in vivo: mechanism of transduction. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 290-5. PMID 18087261 DOI: 10.1038/Sj.Mt.6300376 |
0.476 |
|
| 2008 |
Lyon AR, Sato M, Hajjar RJ, Samulski RJ, Harding SE. Gene therapy: Targeting the myocardium Heart. 94: 89-99. PMID 18083952 DOI: 10.1136/Hrt.2007.116483 |
0.41 |
|
| 2008 |
Wu Z, Sun J, Zhang T, Yin C, Yin F, Van Dyke T, Samulski RJ, Monahan PE. Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 280-9. PMID 18059373 DOI: 10.1038/Sj.Mt.6300355 |
0.437 |
|
| 2007 |
Choi VW, Asokan A, Haberman RA, Samulski RJ. Production of recombinant adeno-associated viral vectors. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 12.9. PMID 18428408 DOI: 10.1002/0471142905.Hg1209S53 |
0.539 |
|
| 2007 |
Choi VW, Asokan A, Haberman RA, Samulski RJ. Production of recombinant adeno-associated viral vectors for in vitro and in vivo use. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 16.25. PMID 18265393 DOI: 10.1002/0471142727.Mb1625S78 |
0.547 |
|
| 2007 |
Foti S, Haberman RP, Samulski RJ, McCown TJ. Adeno-associated virus-mediated expression and constitutive secretion of NPY or NPY13-36 suppresses seizure activity in vivo. Gene Therapy. 14: 1534-6. PMID 17713567 DOI: 10.1038/Sj.Gt.3303013 |
0.352 |
|
| 2007 |
Wang J, Xie J, Lu H, Chen L, Hauck B, Samulski RJ, Xiao W. Existence of transient functional double-stranded DNA intermediates during recombinant AAV transduction. Proceedings of the National Academy of Sciences of the United States of America. 104: 13104-9. PMID 17664425 DOI: 10.1073/Pnas.0702778104 |
0.504 |
|
| 2007 |
Yokoi K, Kachi S, Zhang HS, Gregory PD, Spratt SK, Samulski RJ, Campochiaro PA. Ocular gene transfer with self-complementary AAV vectors. Investigative Ophthalmology & Visual Science. 48: 3324-8. PMID 17591905 DOI: 10.1167/iovs.06-1306 |
0.314 |
|
| 2007 |
Grieger JC, Johnson JS, Gurda-Whitaker B, Agbandje-McKenna M, Samulski RJ. Surface-exposed adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of noninfectious wild-type Vp2/Vp3 and Vp3-only capsids but not that of fivefold pore mutant virions. Journal of Virology. 81: 7833-43. PMID 17507473 DOI: 10.1128/Jvi.00580-07 |
0.763 |
|
| 2007 |
Li C, Hirsch M, Asokan A, Zeithaml B, Ma H, Kafri T, Samulski RJ. Adeno-associated virus type 2 (AAV2) capsid-specific cytotoxic T lymphocytes eliminate only vector-transduced cells coexpressing the AAV2 capsid in vivo. Journal of Virology. 81: 7540-7. PMID 17475652 DOI: 10.1128/Jvi.00529-07 |
0.496 |
|
| 2007 |
Maynor BW, LaRue I, Hu Z, Rolland JP, Pandya A, Fu Q, Liu J, Spontak RJ, Sheiko SS, Samulski RJ, Samulski ET, DeSimone JM. Supramolecular nanomimetics: replication of micelles, viruses, and other naturally occurring nanoscale objects. Small (Weinheim An Der Bergstrasse, Germany). 3: 845-9. PMID 17393549 DOI: 10.1002/Smll.200600507 |
0.306 |
|
| 2006 |
Choi VW, Asokan A, Haberman RA, McCown TJ, Samulski RJ. Production of recombinant adeno-associated viral vectors and use for in vitro and in vivo administration. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 4.17. PMID 18428636 DOI: 10.1002/0471142301.ns0417s35 |
0.452 |
|
| 2006 |
Grieger JC, Choi VW, Samulski RJ. Production and characterization of adeno-associated viral vectors. Nature Protocols. 1: 1412-28. PMID 17406430 DOI: 10.1038/Nprot.2006.207 |
0.791 |
|
| 2006 |
Choi VW, McCarty DM, Samulski RJ. Host cell DNA repair pathways in adeno-associated viral genome processing. Journal of Virology. 80: 10346-56. PMID 17041215 DOI: 10.1128/Jvi.00841-06 |
0.315 |
|
| 2006 |
Wu Z, Asokan A, Grieger JC, Govindasamy L, Agbandje-McKenna M, Samulski RJ. Single amino acid changes can influence titer, heparin binding, and tissue tropism in different adeno-associated virus serotypes. Journal of Virology. 80: 11393-7. PMID 16943302 DOI: 10.1128/Jvi.01288-06 |
0.774 |
|
| 2006 |
Wu Z, Miller E, Agbandje-McKenna M, Samulski RJ. Alpha2,3 and alpha2,6 N-linked sialic acids facilitate efficient binding and transduction by adeno-associated virus types 1 and 6. Journal of Virology. 80: 9093-103. PMID 16940521 DOI: 10.1128/Jvi.00895-06 |
0.358 |
|
| 2006 |
Asokan A, Hamra JB, Govindasamy L, Agbandje-McKenna M, Samulski RJ. Adeno-associated virus type 2 contains an integrin alpha5beta1 binding domain essential for viral cell entry. Journal of Virology. 80: 8961-9. PMID 16940508 DOI: 10.1128/Jvi.00843-06 |
0.403 |
|
| 2006 |
Wu Z, Asokan A, Samulski RJ. Adeno-associated virus serotypes: vector toolkit for human gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 316-27. PMID 16824801 DOI: 10.1016/J.Ymthe.2006.05.009 |
0.425 |
|
| 2006 |
Grieger JC, Snowdy S, Samulski RJ. Separate basic region motifs within the adeno-associated virus capsid proteins are essential for infectivity and assembly. Journal of Virology. 80: 5199-210. PMID 16699000 DOI: 10.1128/Jvi.02723-05 |
0.791 |
|
| 2006 |
McPhee SW, Janson CG, Li C, Samulski RJ, Camp AS, Francis J, Shera D, Lioutermann L, Feely M, Freese A, Leone P. Immune responses to AAV in a phase I study for Canavan disease. The Journal of Gene Medicine. 8: 577-88. PMID 16532510 DOI: 10.1002/Jgm.885 |
0.352 |
|
| 2006 |
Borrás T, Xue W, Choi VW, Bartlett JS, Li G, Samulski RJ, Chisolm SS. Mechanisms of AAV transduction in glaucoma-associated human trabecular meshwork cells. The Journal of Gene Medicine. 8: 589-602. PMID 16506246 DOI: 10.1002/Jgm.886 |
0.474 |
|
| 2006 |
Asokan A, Samulski RJ. AAV does the shuffle. Nature Biotechnology. 24: 158-60. PMID 16465157 DOI: 10.1038/Nbt0206-158 |
0.362 |
|
| 2006 |
Asokan A, Johnson JS, Samulski RJ. 739. Bioluminescent Virion Shells: A Novel Tool for Visualization of Viral Vectors in Animal Tissue Molecular Therapy. 13: S286. DOI: 10.1016/J.Ymthe.2006.08.821 |
0.491 |
|
| 2006 |
Goodrich LR, Choi VW, DudaCarbone BC, McIlwraith CW, Samulski RJ. 493. High Efficiency Gene Targeting to Mammalian Joint Tissue Using Self- Complementary Adeno-Associated Viral Vector Serotypes Molecular Therapy. 13: S191. DOI: 10.1016/J.Ymthe.2006.08.563 |
0.427 |
|
| 2006 |
Markakis EA, Leranth C, Bober J, Samulski RJ, Rabinowitz J, Zhou X, Vives K, Redmond, Jr DE. 113. Transduction of Neural Cells in Primate Brain Using Adeno-Associated Virus (AAV) Serotypes 2 and 5 Molecular Therapy. 13: S46-S47. DOI: 10.1016/J.Ymthe.2006.08.133 |
0.327 |
|
| 2006 |
DiPrimio N, Asokan A, Samulski RJ. 104. Role of the HI Loop in the Adeno- Associated Virus (AAV) Life Cycle Molecular Therapy. 13: S43. DOI: 10.1016/J.Ymthe.2006.08.124 |
0.801 |
|
| 2006 |
Asokan A, Hamra JB, Agbandje-McKenna M, Samulski RJ. 7. Adeno-Associated Virus Type 2 (AAV2) Contains an Integrin alpha5beta1 Recognition Sequence Essential for Viral Cell Entry Molecular Therapy. 13: S3. DOI: 10.1016/J.Ymthe.2006.08.017 |
0.401 |
|
| 2006 |
Markakis E, Leranth C, Bober J, Samulski R, Rabinowitz J, Zhou X, Vives K, Redmond D. Efficiency of gene delivery among AAV serotypes in primate brain Experimental Neurology. 198: 580-581. DOI: 10.1016/J.Expneurol.2006.02.071 |
0.35 |
|
| 2005 |
Grieger JC, Samulski RJ. Adeno-associated virus as a gene therapy vector: vector development, production and clinical applications. Advances in Biochemical Engineering/Biotechnology. 99: 119-45. PMID 16568890 DOI: 10.1007/10_005 |
0.814 |
|
| 2005 |
Grieger JC, Samulski RJ. Packaging capacity of adeno-associated virus serotypes: impact of larger genomes on infectivity and postentry steps. Journal of Virology. 79: 9933-44. PMID 16014954 DOI: 10.1128/Jvi.79.15.9933-9944.2005 |
0.789 |
|
| 2005 |
Choi VW, McCarty DM, Samulski RJ. AAV hybrid serotypes: improved vectors for gene delivery. Current Gene Therapy. 5: 299-310. PMID 15975007 DOI: 10.2174/1566523054064968 |
0.39 |
|
| 2005 |
Li C, Bowles DE, Van Dyke T, Samulski RJ. Adeno-associated virus vectors: Potential applications for cancer gene therapy Cancer Gene Therapy. 12: 913-925. PMID 15962012 DOI: 10.1038/Sj.Cgt.7700876 |
0.485 |
|
| 2005 |
Hacker UT, Wingenfeld L, Kofler DM, Schuhmann NK, Lutz S, Herold T, King SB, Gerner FM, Perabo L, Rabinowitz J, McCarty DM, Samulski RJ, Hallek M, Büning H. Adeno-associated virus serotypes 1 to 5 mediated tumor cell directed gene transfer and improvement of transduction efficiency. The Journal of Gene Medicine. 7: 1429-38. PMID 15945124 DOI: 10.1002/Jgm.782 |
0.499 |
|
| 2005 |
Asokan A, Samulski RJ. From crystal structure to clinic: highlights of the Tenth International Parvovirus Workshop. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 656-60. PMID 15892211 DOI: 10.1016/J.Ymthe.2005.03.014 |
0.417 |
|
| 2005 |
Choi VW, Samulski RJ, McCarty DM. Effects of adeno-associated virus DNA hairpin structure on recombination. Journal of Virology. 79: 6801-7. PMID 15890919 DOI: 10.1128/Jvi.79.11.6801-6807.2005 |
0.309 |
|
| 2005 |
Li C, Samulski RJ. Serotype-specific replicating AAV helper constructs increase recombinant AAV type 2 vector production. Virology. 335: 10-21. PMID 15823602 DOI: 10.1016/j.virol.2005.02.008 |
0.454 |
|
| 2005 |
Xu D, McCarty D, Fernandes A, Fisher M, Samulski RJ, Juliano RL. Delivery of MDR1 small interfering RNA by self-complementary recombinant adeno-associated virus vector Molecular Therapy. 11: 523-530. PMID 15771955 DOI: 10.1016/J.Ymthe.2004.12.019 |
0.458 |
|
| 2005 |
Chen S, Kapturczak M, Loiler SA, Zolotukhin S, Glushakova OY, Madsen KM, Samulski RJ, Hauswirth WW, Campbell-Thompson M, Berns KI, Flotte TR, Atkinson MA, Tisher CC, Agarwal A. Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectors. Human Gene Therapy. 16: 235-47. PMID 15761263 DOI: 10.1089/Hum.2005.16.235 |
0.49 |
|
| 2005 |
Flierl A, Chen Y, Coskun PE, Samulski RJ, Wallace DC. Adeno-associated virus-mediated gene transfer of the heart/muscle adenine nucleotide translocator (ANT) in mouse Gene Therapy. 12: 570-578. PMID 15647764 DOI: 10.1038/Sj.Gt.3302443 |
0.341 |
|
| 2005 |
Fu H, Muenzer J, Kang L, Jennings JS, Samulski RJ, McCarty DM. 854. Optimization of AAV Serotype and Promoter for Increased Distribution of Expression in Both Somatic and Central Nervous Systems of Mice Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.397 |
0.447 |
|
| 2005 |
Duan H, Li C, Samulski RJ. 464. Development of a Novel Gene Regulation System Downstream of Promoter Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.004 |
0.406 |
|
| 2005 |
McCarty DM, Choi V, Fernandes A, Samulski RJ. 403. Defined Vector Substrates Used To Probe rAAV DNA Integration Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.406 |
0.435 |
|
| 2005 |
Suwanmanee T, Choi VW, Samulski RJ, Kafri T, Kole R. 343. Repair of Thalassemic |[beta]|-Globin pre-mRNA by Antisense AAV and Lentiviral Vectors in Cell Culture Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.346 |
0.355 |
|
| 2005 |
Choi VW, McCarty DM, Samulski RJ. 18. Facilitation of AAV Genome Circularization by Host Cell Factors Involved in DNA Replication and Double-Strand Break Repair Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.021 |
0.389 |
|
| 2004 |
McCarty DM, Young SM, Samulski RJ. Integration of adeno-associated virus (AAV) and recombinant AAV vectors. Annual Review of Genetics. 38: 819-45. PMID 15568995 DOI: 10.1146/annurev.genet.37.110801.143717 |
0.39 |
|
| 2004 |
Du L, Kido M, Lee DV, Rabinowitz JE, Samulski RJ, Jamieson SW, Weitzman MD, Thistlethwaite PA. Differential myocardial gene delivery by recombinant serotype-specific adeno-associated viral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 604-8. PMID 15336660 DOI: 10.1016/j.ymthe.2004.06.110 |
0.408 |
|
| 2004 |
Negishi A, Chen J, McCarty DM, Samulski RJ, Liu J, Superfine R. Analysis of the interaction between adeno-associated virus and heparan sulfate using atomic force microscopy. Glycobiology. 14: 969-77. PMID 15215232 DOI: 10.1093/Glycob/Cwh118 |
0.352 |
|
| 2004 |
Rabinowitz JE, Bowles DE, Faust SM, Ledford JG, Cunningham SE, Samulski RJ. Cross-dressing the virion: the transcapsidation of adeno-associated virus serotypes functionally defines subgroups. Journal of Virology. 78: 4421-32. PMID 15078923 DOI: 10.1128/Jvi.78.9.4421-4432.2004 |
0.376 |
|
| 2004 |
Chenuaud P, Larcher T, Rabinowitz JE, Provost N, Joussemet B, Bujard H, Samulski RJ, Favre D, Moullier P. Optimal design of a single recombinant adeno-associated virus derived from serotypes 1 and 2 to achieve more tightly regulated transgene expression from nonhuman primate muscle. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 410-8. PMID 15006608 DOI: 10.1016/J.Ymthe.2003.12.015 |
0.376 |
|
| 2004 |
Stilwell JL, Samulski RJ. Role of viral vectors and virion shells in cellular gene expression. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 337-46. PMID 15006600 DOI: 10.1016/J.Ymthe.2003.11.007 |
0.521 |
|
| 2004 |
Chenuaud P, Larcher T, Rabinowitz JE, Provost N, Cherel Y, Casadevall N, Samulski RJ, Moullier P. Autoimmune anemia in macaques following erythropoietin gene therapy. Blood. 103: 3303-4. PMID 14739218 DOI: 10.1182/Blood-2003-11-3845 |
0.481 |
|
| 2004 |
Allen NA, Samulski RJ. The pros and cons of using the mechanism of AAV site-specific recombination in gene delivery Gene Therapy and Regulation. 2: 121-138. DOI: 10.1163/156855803322664619 |
0.396 |
|
| 2004 |
Qian HS, Liu P, Szymanski P, Kretschmer P, Brooks A, Bauzon M, Jin F, Harkins RN, Samulski RJ, Rubanyi GM, Hermiston TW. 238. A Comparison of Gene Delivery and Vector Systems to Achieve High Levels of Sustained Skeletal Muscle Gene Expression Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.173 |
0.422 |
|
| 2004 |
Fu H, Muenzer J, Samulski RJ, Lu K, Jennings JS, McCarty DM. 94. Targeting Endothelial Cells in Mice with Adeno-Associated Virus Serotype 1 Vector Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.029 |
0.406 |
|
| 2004 |
Grieger JC, Rabinowitz JE, Bowles DE, Samulski RJ. 17. Role of Vp2 in AAV Packaging Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.098 |
0.796 |
|
| 2004 |
McCarty DM, Choi V, Samulski RJ. 11. Reporter Gene-Based Analysis of rAAV Genome Circularization and Recombination Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.092 |
0.372 |
|
| 2003 |
Fu H, Muenzer J, Samulski RJ, Breese G, Sifford J, Zeng X, McCarty DM. Self-complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 911-7. PMID 14664793 DOI: 10.1016/J.Ymthe.2003.08.021 |
0.443 |
|
| 2003 |
McCarty DM, Fu H, Monahan PE, Toulson CE, Naik P, Samulski RJ. Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo. Gene Therapy. 10: 2112-8. PMID 14625565 DOI: 10.1038/Sj.Gt.3302134 |
0.5 |
|
| 2003 |
Stilwell JL, Samulski RJ. Adeno-associated virus vectors for therapeutic gene transfer. Biotechniques. 34: 148-50, 152, 154 pas. PMID 12545552 DOI: 10.2144/03341Dd01 |
0.409 |
|
| 2003 |
Weitzman MD, Young SM, Cathomen T, Samulski RJ. Targeted integration by adeno-associated virus. Methods in Molecular Medicine. 76: 201-19. PMID 12526165 DOI: 10.1385/1-59259-304-6:201 |
0.403 |
|
| 2003 |
Bowles DE, Rabinowitz JE, Samulski RJ. Marker rescue of adeno-associated virus (AAV) capsid mutants: A novel approach for chimeric AAV production Journal of Virology. 77: 423-432. PMID 12477847 DOI: 10.1128/JVI.77.1.423-432.2003 |
0.435 |
|
| 2002 |
McAllister K, Sazani P, Adam M, Cho MJ, Rubinstein M, Samulski RJ, DeSimone JM. Polymeric nanogels produced via inverse microemulsion polymerization as potential gene and antisense delivery agents. Journal of the American Chemical Society. 124: 15198-207. PMID 12487595 DOI: 10.1021/Ja027759Q |
0.344 |
|
| 2002 |
Fu H, Samulski RJ, McCown TJ, Picornell YJ, Fletcher D, Muenzer J. Neurological correction of lysosomal storage in a mucopolysaccharidosis IIIB mouse model by adeno-associated virus-mediated gene delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 42-9. PMID 11786044 DOI: 10.1006/Mthe.2001.0514 |
0.464 |
|
| 2002 |
Rabinowitz JE, Rolling F, Li C, Conrath H, Xiao W, Xiao X, Samulski RJ. Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity. Journal of Virology. 76: 791-801. PMID 11752169 DOI: 10.1128/Jvi.76.2.791-801.2002 |
0.449 |
|
| 2001 |
Young SM, Samulski RJ. Adeno-associated virus (AAV) site-specific recombination does not require a Rep-dependent origin of replication within the AAV terminal repeat. Proceedings of the National Academy of Sciences of the United States of America. 98: 13525-30. PMID 11707592 DOI: 10.1073/Pnas.241508998 |
0.427 |
|
| 2001 |
McCarty DM, Monahan PE, Samulski RJ. Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis. Gene Therapy. 8: 1248-54. PMID 11509958 DOI: 10.1038/Sj.Gt.3301514 |
0.47 |
|
| 2001 |
Amiss TJ, Samulski RJ. Methods for adeno-associated virus-mediated gene transfer into muscle. Methods in Molecular Biology (Clifton, N.J.). 175: 455-69. PMID 11462851 DOI: 10.1385/1-59259-235-X:455 |
0.435 |
|
| 2000 |
Chao H, Liu Y, Rabinowitz J, Li C, Samulski RJ, Walsh CE. Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 619-23. PMID 11124063 DOI: 10.1006/Mthe.2000.0219 |
0.455 |
|
| 2000 |
Rabinowitz JE, Samulski RJ. Building a better vector: The manipulation of AAV virions Virology. 278: 301-308. PMID 11118354 DOI: 10.1006/Viro.2000.0707 |
0.392 |
|
| 2000 |
Monahan PE, Samulski RJ. Adeno-associated virus vectors for gene therapy: more pros than cons? Molecular Medicine Today. 6: 433-40. PMID 11074369 DOI: 10.1016/S1357-4310(00)01810-4 |
0.427 |
|
| 2000 |
Haberman RP, McCown TJ, Samulski RJ. Novel transcriptional regulatory signals in the adeno-associated virus terminal repeat A/D junction element. Journal of Virology. 74: 8732-9. PMID 10954575 DOI: 10.1128/Jvi.74.18.8732-8739.2000 |
0.474 |
|
| 2000 |
Carter PJ, Samulski RJ. Adeno-associated viral vectors as gene delivery vehicles. International Journal of Molecular Medicine. 6: 17-27. PMID 10851261 DOI: 10.3892/ijmm.6.1.17 |
0.407 |
|
| 2000 |
Samulski RJ. Expanding the AAV package Nature Biotechnology. 18: 497-498. PMID 10802614 DOI: 10.1038/75352 |
0.35 |
|
| 2000 |
Young SM, McCarty DM, Degtyareva N, Samulski RJ. Roles of adeno-associated virus Rep protein and human chromosome 19 in site-specific recombination. Journal of Virology. 74: 3953-66. PMID 10756007 DOI: 10.1128/Jvi.74.9.3953-3966.2000 |
0.37 |
|
| 2000 |
Malik AK, Monahan PE, Allen DL, Chen BG, Samulski RJ, Kurachi K. Kinetics of recombinant adeno-associated virus-mediated gene transfer. Journal of Virology. 74: 3555-65. PMID 10729130 DOI: 10.1128/JVI.74.8.3555-3565.2000 |
0.392 |
|
| 2000 |
Pruchnic R, Cao B, Peterson ZQ, Xiao X, Li J, Samulski RJ, Epperly M, Huard J. The use of adeno-associated virus to circumvent the maturation-dependent viral transduction of muscle fibers Human Gene Therapy. 11: 521-536. PMID 10724031 DOI: 10.1089/10430340050015716 |
0.478 |
|
| 2000 |
Bartlett JS, Wilcher R, Samulski RJ. Infectious entry pathway of adeno-associated virus and adeno-associated virus vectors Journal of Virology. 74: 2777-2785. PMID 10684294 DOI: 10.1128/JVI.74.6.2777-2785.2000 |
0.424 |
|
| 2000 |
Monahan PE, Samulski RJ. AAV vectors: is clinical success on the horizon? Gene Therapy. 7: 24-30. PMID 10680012 DOI: 10.1038/Sj.Gt.3301109 |
0.482 |
|
| 2000 |
Summerford C, Bartlett JS, Samulski RJ. Adeno-associated viral vectors and successful gene therapy, the gap is closing Gene Therapy and Regulation. 1: 9-32. DOI: 10.1163/156855800744511 |
0.501 |
|
| 2000 |
Gavin DK, Young SM, Xiao W, Temple B, Abernathy CR, Pereira DJ, Muzyczka N, Samulski RJ. Charge-to-Alanine Mutagenesis of the Adeno-Associated Virus Type 2 Rep78/68 Proteins Yields Temperature-Sensitive and Magnesium-Dependent Variants Journal of Virology. 74: 591-591. DOI: 10.1128/Jvi.74.1.591-591.2000 |
0.645 |
|
| 1999 |
Rabinowitz JE, Xiao W, Samulski RJ. Insertional mutagenesis of AAV2 capsid and the production of recombinant virus Virology. 265: 274-285. PMID 10600599 DOI: 10.1006/Viro.1999.0045 |
0.386 |
|
| 1999 |
Chao H, Samulski R, Bellinger D, Monahan P, Nichols T, Walsh C. Persistent expression of canine factor IX in hemophilia B canines. Gene Therapy. 6: 1695-704. PMID 10516718 DOI: 10.1038/Sj.Gt.3301024 |
0.439 |
|
| 1999 |
Gavin DK, Young SM, Xiao W, Temple B, Abernathy CR, Pereira DJ, Muzyczka N, Samulski RJ. Charge-to-alanine mutagenesis of the adeno-associated virus type 2 Rep78/68 proteins yields temperature-sensitive and magnesium-dependent variants. Journal of Virology. 73: 9433-45. PMID 10516052 |
0.61 |
|
| 1999 |
Grimm D, Kern A, Pawlita M, Ferrari F, Samulski R, Kleinschmidt J. Titration of AAV-2 particles via a novel capsid ELISA: packaging of genomes can limit production of recombinant AAV-2. Gene Therapy. 6: 1322-30. PMID 10455443 DOI: 10.1038/Sj.Gt.3300946 |
0.422 |
|
| 1999 |
Zolotukhin S, Byrne BJ, Mason E, Zolotukhin I, Potter M, Chesnut K, Summerford C, Samulski RJ, Muzyczka N. Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield. Gene Therapy. 6: 973-85. PMID 10455399 DOI: 10.1038/Sj.Gt.3300938 |
0.598 |
|
| 1999 |
Summerford C, Samulski RJ. Viral receptors and vector purification: New approaches for generating clinical-grade reagents Nature Medicine. 5: 587-558. PMID 10229239 DOI: 10.1038/8470 |
0.364 |
|
| 1999 |
Bartlett JS, Kleinschmidt J, Boucher RC, Samulski RJ. Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab'gamma)2 antibody. Nature Biotechnology. 17: 181-6. PMID 10052356 DOI: 10.1038/6185 |
0.325 |
|
| 1999 |
Summerford C, Bartlett JS, Samulski RJ. αVβ5 integrin: A co-receptor for adeno-associated virus type 2 infection Nature Medicine. 5: 78-82. PMID 9883843 DOI: 10.1038/4768 |
0.46 |
|
| 1999 |
Samulski RJ, Sally M, Muzyczka N. 7 Adeno-associated Viral Vectors Cold Spring Harbor Monograph Archive. 36: 131-172. DOI: 10.1101/087969528.36.131 |
0.716 |
|
| 1999 |
Samulski RJ. Adeno-associated virus vectors; Gene therapy and viral vectors, the gap is closing Biochemical Society Transactions. 27: A136-A136. DOI: 10.1042/bst027a136c |
0.425 |
|
| 1999 |
Samulski RJ, Bartlett JS, Summerford C. Adeno-associated virus 2 co-receptors?-second reply Nature Medicine. 5: 468-468. DOI: 10.1038/8330 |
0.386 |
|
| 1999 |
Haberman RA, Kroner‐Lux G, Samulski RJ. Production of Recombinant Adeno‐Associated Viral Vectors Current Protocols in Human Genetics. 23. DOI: 10.1002/0471142905.Hg1209S23 |
0.47 |
|
| 1998 |
Haberman RP, McCown TJ, Samulski RJ. Inducible long-term gene expression in brain with adeno-associated virus gene transfer. Gene Therapy. 5: 1604-11. PMID 10023439 DOI: 10.1038/Sj.Gt.3300782 |
0.459 |
|
| 1998 |
Teramoto S, Bartlett JS, Mccarty D, Xiao X, Samulski RJ, Boucher RC. Factors influencing adeno-associated virus-mediated gene transfer to human cystic fibrosis airway epithelial cells: Comparison with adenovirus vectors Journal of Virology. 72: 8904-8912. PMID 9765435 DOI: 10.1128/Jvi.72.11.8904-8912.1998 |
0.471 |
|
| 1998 |
During MJ, Samulski RJ, Elsworth JD, Kaplitt MG, Leone P, Xiao X, Li J, Freese A, Taylor JR, Roth RH, Sladek JR, O'Malley KL, Redmond DE. In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector. Gene Therapy. 5: 820-7. PMID 9747462 DOI: 10.1038/Sj.Gt.3300650 |
0.385 |
|
| 1998 |
Bartlett JS, Samulski RJ, McCown TJ. Selective and rapid uptake of adeno-associated virus type 2 in brain. Human Gene Therapy. 9: 1181-6. PMID 9625257 DOI: 10.1089/hum.1998.9.8-1181 |
0.331 |
|
| 1998 |
Bartlett JS, Samulski RJ. Fluorescent viral vectors: A new technique for the pharmacological analysis of gene therapy Nature Medicine. 4: 635-637. PMID 9585242 DOI: 10.1038/Nm0598-635 |
0.41 |
|
| 1998 |
Monahan PE, Samulski RJ, Tazelaar J, Xiao X, Nichols TC, Bellinger DA, Read MS, Walsh CE. Direct intramuscular injection with recombinant AAV vectors results in sustained expression in a dog model of hemophilia. Gene Therapy. 5: 40-9. PMID 9536263 DOI: 10.1038/Sj.Gt.3300548 |
0.481 |
|
| 1998 |
Xiao X, Juan LI, Samulski RJ. Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus Journal of Virology. 72: 2224-2232. PMID 9499080 DOI: 10.1128/Jvi.72.3.2224-2232.1998 |
0.495 |
|
| 1998 |
Summerford C, Samulski RJ. Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions Journal of Virology. 72: 1438-1445. PMID 9445046 DOI: 10.1128/Jvi.72.2.1438-1445.1998 |
0.48 |
|
| 1998 |
Xiao X, Li J, Samulski RJ. Production of High-Titer Recombinant Adeno-Associated Virus Vectors in the Absence of Helper Adenovirus Journal of Virology. 72: 2224-2232. DOI: 10.1128/jvi.72.3.2224-2232.1998 |
0.395 |
|
| 1998 |
Summerford C, Samulski RJ. Membrane-Associated Heparan Sulfate Proteoglycan Is a Receptor for Adeno-Associated Virus Type 2 Virions Journal of Virology. 72: 1438-1445. DOI: 10.1128/jvi.72.2.1438-1445.1998 |
0.377 |
|
| 1998 |
Teramoto S, Bartlett JS, McCarty D, Xiao X, Samulski RJ, Boucher RC. Factors Influencing Adeno-Associated Virus-Mediated Gene Transfer to Human Cystic Fibrosis Airway Epithelial Cells: Comparison with Adenovirus Vectors Journal of Virology. 72: 8904-8912. DOI: 10.1128/jvi.72.11.8904-8912.1998 |
0.367 |
|
| 1998 |
Summerford C, Samulski RJ. Adeno-associated viral vectors for gene therapy Biogenic Amines. 14: 451-475. |
0.382 |
|
| 1997 |
Keir SD, Miller J, Yu G, Hamilton R, Samulski RJ, Xiao X, Tornatore C. Efficient gene transfer into primary and immortalized human fetal glial cells using adeno-associated virus vectors: Establishment of a glial cell line with a functional CD4 receptor Journal of Neurovirology. 3: 322-330. PMID 9372453 DOI: 10.3109/13550289709030746 |
0.386 |
|
| 1997 |
Ferrari FK, Xiao X, McCarty D, Samulski RJ. New developments in the generation of Ad-free, high-titer rAAV gene therapy vectors Nature Medicine. 3: 1295-1297. PMID 9359708 DOI: 10.1038/Nm1197-1295 |
0.373 |
|
| 1997 |
Li J, Samulski RJ, Xiao X. Role for highly regulated rep gene expression in adeno-associated virus vector production Journal of Virology. 71: 5236-5243. PMID 9188591 DOI: 10.1128/Jvi.71.7.5236-5243.1997 |
0.507 |
|
| 1997 |
Xiao X, Li J, McCown TJ, Samulski RJ. Gene transfer by adeno-associated virus vectors into the central nervous system. Experimental Neurology. 144: 113-24. PMID 9126160 DOI: 10.1006/Exnr.1996.6396 |
0.535 |
|
| 1997 |
Xiao X, Xiao W, Li J, Samulski RJ. A novel 165-base-pair terminal repeat sequence is the sole cis requirement for the adeno-associated virus life cycle Journal of Virology. 71: 941-948. PMID 8995611 DOI: 10.1128/Jvi.71.2.941-948.1997 |
0.478 |
|
| 1997 |
Li J, Samulski RJ, Xiao X. Role for highly regulated rep gene expression in adeno-associated virus vector production. Journal of Virology. 71: 5236-5243. DOI: 10.1128/jvi.71.7.5236-5243.1997 |
0.364 |
|
| 1997 |
Yang CC, Xiao X, Zhu X, Ansardi DC, Epstein ND, Frey MR, Matera AG, Samulski RJ. Cellular recombination pathways and viral terminal repeat hairpin structures are sufficient for adeno-associated virus integration in vivo and in vitro. Journal of Virology. 71: 9231-9247. DOI: 10.1128/jvi.71.12.9231-9247.1997 |
0.359 |
|
| 1997 |
Samulski RJ, During MJ, Kaplitt MG, Xiao X, Redman G, McCown T. Adeno-associated virus vectors yield long-term expression and delivery of potentially therapeutic genes into non-dividing neuronal cells Journal of Neurovirology. 3: S72. |
0.337 |
|
| 1996 |
Kaplitt MG, Xiao X, Samulski RJ, Li J, Ojamaa K, Klein IL, Makimura H, Kaplitt MJ, Strumpf RK, Diethrich EB. Long-term gene transfer in porcine myocardium after coronary infusion of an adeno-associated virus vector. The Annals of Thoracic Surgery. 62: 1669-76. PMID 8957370 DOI: 10.1016/S0003-4975(96)00946-0 |
0.48 |
|
| 1996 |
Xiao X, Li J, Samulski RJ. Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector Journal of Virology. 70: 8098-8108. PMID 8892935 DOI: 10.1128/Jvi.70.11.8098-8108.1996 |
0.491 |
|
| 1996 |
McKeon C, Samulski RJ. NIDDK Workshop on AAV Vectors: Gene transfer into quiescent cells Human Gene Therapy. 7: 1615-1619. PMID 8864762 DOI: 10.1089/Hum.1996.7.13-1615 |
0.413 |
|
| 1996 |
McCarty DM, Samulski RJ. Adeno-associated virus vectors for gene transfer into erythroid cells Current Topics in Microbiology and Immunology. 218: 75-91. PMID 8794247 DOI: 10.1007/978-3-642-80207-2_6 |
0.403 |
|
| 1996 |
McCown TJ, Xiao X, Li J, Breese GR, Samulski RJ. Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector. Brain Research. 713: 99-107. PMID 8724980 DOI: 10.1016/0006-8993(95)01488-8 |
0.424 |
|
| 1996 |
Ferrari FK, Samulski T, Shenk T, Samulski RJ. Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors Journal of Virology. 70: 3227-3234. PMID 8627803 DOI: 10.1128/Jvi.70.5.3227-3234.1996 |
0.662 |
|
| 1996 |
Ferrari FK, Samulski T, Shenk T, Samulski RJ. Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors. Journal of Virology. 70: 3227-3234. DOI: 10.1128/jvi.70.5.3227-3234.1996 |
0.577 |
|
| 1996 |
Xiao X, Li J, Samulski RJ. Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector. Journal of Virology. 70: 8098-8108. DOI: 10.1128/jvi.70.11.8098-8108.1996 |
0.333 |
|
| 1995 |
Rolling F, Samulski RJ. AAV as a viral vector for human gene therapy - Generation of recombinant virus Molecular Biotechnology. 3: 9-15. PMID 7606507 DOI: 10.1007/Bf02821330 |
0.548 |
|
| 1995 |
Skulimowski AW, Samulski RJ. [1] Adeno-associated virus: Integrating vectors for human gene therapy Methods in Molecular Genetics. 7: 3-12. DOI: 10.1016/S1067-2389(06)80033-6 |
0.398 |
|
| 1994 |
Goodman S, Xiao X, Donahue RE, Moulton A, Miller J, Walsh C, Young NS, Samulski RJ, Nienhuis AW. Recombinant adeno-associated virus-mediated gene transfer into hematopoietic progenitor cells. Blood. 84: 1492-500. PMID 8068942 |
0.412 |
|
| 1994 |
Walsh CE, Nienhuis AW, Samulski RJ, Brown MG, Miller JL, Young NS, Liu JM. Phenotypic correction of Fanconi anemia in human hematopoietic cells with a recombinant adeno-associated virus vector. The Journal of Clinical Investigation. 94: 1440-8. PMID 7929819 DOI: 10.1172/Jci117481 |
0.451 |
|
| 1994 |
Kaplitt MG, Leone P, Samulski RJ, Xiao X, Pfaff DW, O'Malley KL, During MJ. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nature Genetics. 8: 148-54. PMID 7842013 DOI: 10.1038/Ng1094-148 |
0.479 |
|
| 1994 |
Miller JL, Donahue RE, Sellers SE, Samulski RJ, Young NS, Nienhuis AW. Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 10183-7. PMID 7524085 DOI: 10.1073/Pnas.91.21.10183 |
0.452 |
|
| 1994 |
Goodman S, Xiao X, Donahue R, Moulton A, Miller J, Walsh C, Young N, Samulski R, Nienhuis A. Recombinant adeno-associated virus-mediated gene transfer into hematopoietic progenitor cells [published erratum appears in Blood 1995 Feb 1;85(3):862] Blood. 84: 1492-1500. DOI: 10.1182/Blood.V84.5.1492.Bloodjournal8451492 |
0.509 |
|
| 1993 |
Snyder RO, Im DS, Ni T, Xiao X, Samulski RJ, Muzyczka N. Features of the adeno-associated virus origin involved in substrate recognition by the viral rep protein Journal of Virology. 67: 6096-6104. PMID 8396670 DOI: 10.1128/Jvi.67.10.6096-6104.1993 |
0.6 |
|
| 1993 |
Samulski RJ. Adeno-associated virus: integration at a specific chromosomal locus Current Opinion in Genetics and Development. 3: 74-80. PMID 8384035 DOI: 10.1016/S0959-437X(05)80344-2 |
0.42 |
|
| 1993 |
Walsh CE, Liu JM, Miller JL, Nienhuis AW, Samulski RJ. Gene therapy for human hemoglobinopathies. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 204: 289-300. PMID 8234372 DOI: 10.3181/00379727-204-43665 |
0.515 |
|
| 1993 |
Snyder RO, Im DS, Ni T, Xiao X, Samulski RJ, Muzyczka N. Features of the adeno-associated virus origin involved in substrate recognition by the viral Rep protein. Journal of Virology. 67: 6096-6104. DOI: 10.1128/jvi.67.10.6096-6104.1993 |
0.593 |
|
| 1992 |
Hunter LA, Samulski RJ. Colocalization of adeno-associated virus rep and capsid proteins in the nuclei of infected cells Journal of Virology. 66: 317-324. PMID 1370086 DOI: 10.1128/Jvi.66.1.317-324.1992 |
0.391 |
|
| 1992 |
Walsh CE, Liu JM, Xiao X, Young NS, Nienhuis AW, Samulski RJ. Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vector. Proceedings of the National Academy of Sciences of the United States of America. 89: 7257-61. PMID 1323131 DOI: 10.1073/Pnas.89.15.7257 |
0.456 |
|
| 1992 |
Muro-Cacho CA, Samulski RJ, Kaplan D. Gene transfer in human lymphocytes using a vector based on adeno-associated virus Journal of Immunotherapy. 11: 231-237. PMID 1318074 DOI: 10.1097/00002371-199205000-00001 |
0.546 |
|
| 1992 |
Cai Q, Samulski RJ, Ricordi C, Lotze MT. ADENO-ASSOCIATED VIRUS (AAV) CAN BE USED AS A POTENTIAL VECTOR TO TRANSFER GENES INTO PANCREATIC ISLETS Journal of Immunotherapy. 11: 122. DOI: 10.1097/00002371-199202000-00013 |
0.477 |
|
| 1991 |
Samulski RJ, Zhu X, Xiao X, Brook JD, Housman DE, Epstein N, Hunter LA. Targeted integration of adeno-associated virus (AAV) into human chromosome 19. The Embo Journal. 10: 3941-50. PMID 1657596 |
0.327 |
|
| 1990 |
Snyder RO, Samulski RJ, Muzyczka N. In vitro resolution of covalently joined AAV chromosome ends Cell. 60: 105-113. PMID 2153052 DOI: 10.1016/0092-8674(90)90720-Y |
0.622 |
|
| 1989 |
Srivastava CH, Samulski RJ, Lu L, Larsen SH, Srivastava A. Construction of a recombinant human parvovirus B19: adeno-associated virus 2 (AAV) DNA inverted terminal repeats are functional in an AAV-B19 hybrid virus. Proceedings of the National Academy of Sciences of the United States of America. 86: 8078-82. PMID 2554300 DOI: 10.1073/Pnas.86.20.8078 |
0.465 |
|
| 1989 |
Samulski RJ, Chang LS, Shenk T. Helper-free stocks of recombinant adeno-associated viruses: Normal integration does not require viral gene expression Journal of Virology. 63: 3822-3828. PMID 2547998 DOI: 10.1128/Jvi.63.9.3822-3828.1989 |
0.648 |
|
| 1989 |
Samulski RJ, Chang LS, Shenk T. Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression. Journal of Virology. 63: 3822-3828. DOI: 10.1128/jvi.63.9.3822-3828.1989 |
0.599 |
|
| 1988 |
Samulski RJ, Shenk T. Adenovirus E1B 55-M(r) polypeptide facilitates timely cytoplasmic accumulation of adeno-associated virus mRNAs Journal of Virology. 62: 206-210. PMID 2824848 DOI: 10.1128/Jvi.62.1.206-210.1988 |
0.469 |
|
| 1988 |
Samulski RJ, Shenk T. Adenovirus E1B 55-Mr polypeptide facilitates timely cytoplasmic accumulation of adeno-associated virus mRNAs. Journal of Virology. 62: 206-210. DOI: 10.1128/jvi.62.1.206-210.1988 |
0.512 |
|
| 1987 |
Hearing P, Samulski RJ, Wishart WL, Shenk T. Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome Journal of Virology. 61: 2555-2558. PMID 3599182 DOI: 10.1128/Jvi.61.8.2555-2558.1987 |
0.524 |
|
| 1987 |
Samulski RJ, Chang LS, Shenk T. A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication Journal of Virology. 61: 3096-3101. PMID 3041032 |
0.617 |
|
| 1987 |
Hearing P, Samulski RJ, Wishart WL, Shenk T. Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome. Journal of Virology. 61: 2555-2558. DOI: 10.1128/jvi.61.8.2555-2558.1987 |
0.436 |
|
| 1987 |
Samulski RJ, Chang LS, Shenk T. A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication. Journal of Virology. 61: 3096-3101. DOI: 10.1128/jvi.61.10.3096-3101.1987 |
0.588 |
|
| 1984 |
Muzyczka N, Samulski RJ, Hermonat P, Srivastava A, Berns KI. The genetics of adeno-associated virus. Advances in Experimental Medicine and Biology. 179: 151-61. PMID 6098150 DOI: 10.1007/978-1-4684-8730-5_15 |
0.681 |
|
| 1983 |
Samulski RJ, Srivastava A, Berns KI, Muzyczka N. Rescue of adeno-associated virus from recombinant plasmids: gene correction within the terminal repeats of AAV. Cell. 33: 135-43. PMID 6088052 DOI: 10.1016/0092-8674(83)90342-2 |
0.628 |
|
| 1982 |
Samulski RJ, Berns KI, Tan M, Muzyczka N. Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 2077-81. PMID 6281795 DOI: 10.1073/Pnas.79.6.2077 |
0.667 |
|
| Show low-probability matches. |