Michael J. Mahan - Publications

Affiliations: 
University of California, Santa Barbara, Santa Barbara, CA, United States 
Area:
Microbiology Biology

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Pimienta G, Heithoff DM, Rosa-Campos A, Tran M, Esko JD, Mahan MJ, Marth JD, Smith JW. Plasma Proteome Signature of Sepsis: a Functionally Connected Protein Network. Proteomics. e1800389. PMID 30706660 DOI: 10.1002/pmic.201800389  0.76
2018 Yang WH, Heithoff DM, Aziz PV, Haslund-Gourley B, Westman JS, Narisawa S, Pinkerton AB, Millán JL, Nizet V, Mahan MJ, Marth JD. Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis. Cell Host & Microbe. 24: 500-513.e5. PMID 30308156 DOI: 10.1016/j.chom.2018.09.011  0.76
2018 Barnes L, Heithoff DM, Mahan SP, Fox GN, Zambrano A, Choe J, Fitzgibbons LN, Marth JD, Fried JC, Soh HT, Mahan MJ. Smartphone-based pathogen diagnosis in urinary sepsis patients. Ebiomedicine. PMID 30245056 DOI: 10.1016/j.ebiom.2018.09.001  0.76
2017 Yang WH, Heithoff DM, Aziz PV, Sperandio M, Nizet V, Mahan MJ, Marth JD. Recurrent infection progressively disables host protection against intestinal inflammation. Science (New York, N.Y.). 358. PMID 29269445 DOI: 10.1126/science.aao5610  0.76
2017 Ersoy SC, Heithoff DM, Barnes L, Tripp GK, House JK, Marth JD, Smith JW, Mahan MJ. Correcting a Fundamental Flaw in the Paradigm for Antimicrobial Susceptibility Testing. Ebiomedicine. PMID 28579300 DOI: 10.1016/j.ebiom.2017.05.026  0.76
2015 Kubicek-Sutherland JZ, Heithoff DM, Ersoy SC, Shimp WR, House JK, Marth JD, Smith JW, Mahan MJ. Host-dependent Induction of Transient Antibiotic Resistance: A Prelude to Treatment Failure. Ebiomedicine. 2: 1169-78. PMID 26501114 DOI: 10.1016/j.ebiom.2015.08.012  0.76
2015 Yang WH, Aziz PV, Heithoff DM, Mahan MJ, Smith JW, Marth JD. An intrinsic mechanism of secreted protein aging and turnover. Proceedings of the National Academy of Sciences of the United States of America. 112: 13657-62. PMID 26489654 DOI: 10.1073/pnas.1515464112  0.76
2015 Heithoff DM, Mahan MJ. Pandemic influenza virus: tracking a three-headed monster. Virulence. 6: 405-6. PMID 25738965 DOI: 10.1080/21505594.2015.1020275  0.76
2015 Heithoff DM, House JK, Thomson PC, Mahan MJ. Development of a Salmonella cross-protective vaccine for food animal production systems. Vaccine. 33: 100-7. PMID 25448106 DOI: 10.1016/j.vaccine.2014.11.012  0.76
2014 Kubicek-Sutherland JZ, Heithoff DM, Ersoy SC, Shimp WR, Mahan MJ. Immunization with a DNA adenine methylase over-producing Yersinia pseudotuberculosis vaccine confers robust cross-protection against heterologous pathogenic serotypes. Vaccine. 32: 1451-9. PMID 24508035 DOI: 10.1016/j.vaccine.2014.01.036  0.76
2013 Patterson AS, Heithoff DM, Ferguson BS, Soh HT, Mahan MJ, Plaxco KW. Microfluidic chip-based detection and intraspecies strain discrimination of Salmonella serovars derived from whole blood of septic mice. Applied and Environmental Microbiology. 79: 2302-11. PMID 23354710 DOI: 10.1128/AEM.03882-12  0.76
2013 Mahan MJ, Kubicek-Sutherland JZ, Heithoff DM. Rise of the microbes. Virulence. 4: 213-22. PMID 23334178 DOI: 10.4161/viru.23380  0.76
2012 Mahan MJ, Heithoff DM, House JK. Salmonella cross-protective vaccines: fast-forward to the next generation of food safety. Future Microbiology. 7: 805-8. PMID 22827301 DOI: 10.2217/fmb.12.60  0.76
2012 Heithoff DM, Shimp WR, House JK, Xie Y, Weimer BC, Sinsheimer RL, Mahan MJ. Intraspecies variation in the emergence of hyperinfectious bacterial strains in nature. Plos Pathogens. 8: e1002647. PMID 22511871 DOI: 10.1371/journal.ppat.1002647  0.76
2012 Mohler VL, Heithoff DM, Mahan MJ, Hornitzky MA, Thomson PC, House JK. Development of a novel in-water vaccination protocol for DNA adenine methylase deficient Salmonella enterica serovar Typhimurium vaccine in adult sheep Vaccine. 30: 1481-1491. PMID 22214887 DOI: 10.1016/j.vaccine.2011.12.079  0.76
2011 Mohler VL, Heithoff DM, Mahan MJ, Walker KH, Hornitzky MA, Gabor L, Thomson PC, Thompson A, House JK. Protective immunity conferred by a DNA adenine methylase deficient Salmonella enterica serovar Typhimurium vaccine when delivered in-water to sheep challenged with Salmonella enterica serovar Typhimurium. Vaccine. 29: 3571-82. PMID 21473951 DOI: 10.1016/j.vaccine.2011.03.075  0.76
2008 Heithoff DM, Enioutina EY, Bareyan D, Daynes RA, Mahan MJ. Conditions that diminish myeloid-derived suppressor cell activities stimulate cross-protective immunity. Infection and Immunity. 76: 5191-9. PMID 18765736 DOI: 10.1128/IAI.00759-08  0.76
2008 Mohler VL, Heithoff DM, Mahan MJ, Walker KH, Hornitzky MA, Shum LWC, Makin KJ, House JK. Cross-protective immunity conferred by a DNA adenine methylase deficient Salmonella enterica serovar Typhimurium vaccine in calves challenged with Salmonella serovar Newport Vaccine. 26: 1751-1758. PMID 18329764 DOI: 10.1016/j.vaccine.2008.01.018  0.76
2008 Heithoff DM, Shimp WR, Lau PW, Badie G, Enioutina EY, Daynes RA, Byrne BA, House JK, Mahan MJ. Human Salmonella clinical isolates distinct from those of animal origin. Applied and Environmental Microbiology. 74: 1757-66. PMID 18245251 DOI: 10.1128/AEM.02740-07  0.76
2007 Simon R, Heithoff DM, Mahan MJ, Samuel CE. Comparison of tissue-selective proinflammatory gene induction in mice infected with wild-type, DNA adenine methylase-deficient, and flagellin-deficient Salmonella enterica. Infection and Immunity. 75: 5627-39. PMID 17893133 DOI: 10.1128/IAI.01021-07  0.76
2007 Heithoff DM, Badie G, Julio SM, Enioutina EY, Daynes RA, Sinsheimer RL, Mahan MJ. In vivo-selected mutations in methyl-directed mismatch repair suppress the virulence attenuation of Salmonella dam mutant strains following intraperitoneal, but not oral, infection of naïve mice. Journal of Bacteriology. 189: 4708-17. PMID 17468250 DOI: 10.1128/JB.00299-07  0.76
2007 Badie G, Heithoff DM, Sinsheimer RL, Mahan MJ. Altered levels of Salmonella DNA adenine methylase are associated with defects in gene expression, motility, flagellar synthesis, and bile resistance in the pathogenic strain 14028 but not in the laboratory strain LT2. Journal of Bacteriology. 189: 1556-64. PMID 17172341 DOI: 10.1128/JB.01580-06  0.76
2006 Mohler VL, Heithoff DM, Mahan MJ, Walker KH, Hornitzky MA, McConnell CS, Shum LW, House JK. Cross-protective immunity in calves conferred by a DNA adenine methylase deficient Salmonellaenterica serovar Typhimurium vaccine. Vaccine. 24: 1339-45. PMID 16300866 DOI: 10.1016/j.vaccine.2005.09.022  0.76
2004 Badie G, Heithoff DM, Mahan MJ. LcrV synthesis is altered by DNA adenine methylase overproduction in Yersinia pseudotuberculosis and is required to confer immunity in vaccinated hosts. Infection and Immunity. 72: 6707-10. PMID 15501808 DOI: 10.1128/IAI.72.11.6707-6710.2004  0.76
2004 Heithoff DM, Mahan MJ. Vibrio cholerae biofilms: stuck between a rock and a hard place. Journal of Bacteriology. 186: 4835-7. PMID 15262913 DOI: 10.1128/JB.186.15.4835-4837.2004  0.76
2003 Dueger EL, House JK, Heithoff DM, Mahan MJ. Salmonella DNA adenine methylase mutants elicit early and late onset protective immune responses in calves Vaccine. 21: 3249-3258. PMID 12804855 DOI: 10.1016/S0264-410X(03)00252-4  0.76
2003 Dueger EL, House JK, Heithoff DM, Mahan MJ. Salmonella DNA adenine methylase mutants prevent colonization of newly hatched chickens by homologous and heterologous serovars International Journal of Food Microbiology. 80: 153-159. PMID 12381401 DOI: 10.1016/S0168-1605(02)00152-6  0.76
2002 Shtrichman R, Heithoff DM, Mahan MJ, Samuel CE. Tissue selectivity of interferon-stimulated gene expression in mice infected with Dam(+) versus Dam(-) Salmonella enterica serovar Typhimurium strains. Infection and Immunity. 70: 5579-88. PMID 12228285 DOI: 10.1128/IAI.70.10.5579-5588.2002  0.76
2002 Julio SM, Heithoff DM, Sinsheimer RL, Low DA, Mahan MJ. DNA adenine methylase overproduction in Yersinia pseudotuberculosis alters YopE expression and secretion and host immune responses to infection. Infection and Immunity. 70: 1006-9. PMID 11796641 DOI: 10.1128/IAI.70.2.1006-1009.2002  0.76
2001 Dueger EL, House JK, Heithoff DM, Mahan MJ. Salmonella DNA adenine methylase mutants elicit protective immune responses to homologous and heterologous serovars in chickens Infection and Immunity. 69: 7950-7954. PMID 11705984 DOI: 10.1128/IAI.69.12.7950-7954.2001  0.76
2001 Julio SM, Heithoff DM, Provenzano D, Klose KE, Sinsheimer RL, Low DA, Mahan MJ. DNA adenine methylase is essential for viability and plays a role in the pathogenesis of Yersinia pseudotuberculosis and Vibrio cholerae. Infection and Immunity. 69: 7610-5. PMID 11705940 DOI: 10.1128/IAI.69.12.7610-7615.2001  0.76
2001 Low DA, Weyand NJ, Mahan MJ. Roles of DNA adenine methylation in regulating bacterial gene expression and virulence Infection and Immunity. 69: 7197-7204. PMID 11705888 DOI: 10.1128/IAI.69.12.7197-7204.2001  0.76
2001 Heithoff DM, Enioutina EY, Daynes RA, Sinsheimer RL, Low DA, Mahan MJ. Salmonella DNA adenine methylase mutants confer cross-protective immunity. Infection and Immunity. 69: 6725-30. PMID 11598044 DOI: 10.1128/IAI.69.11.6725-6730.2001  0.76
2001 Low DA, Mahan MJ. Editorial overview: Techniques hosting an infection: The complex interplay between microbes and their hosts Current Opinion in Microbiology. 4: 235-236. DOI: 10.1016/S1369-5274(00)00196-X  0.76
2000 Mahan MJ, Heithoff DM, Sinsheimer RL, Low DA. Assessment of bacterial pathogenesis by analysis of gene expression in the host. Annual Review of Genetics. 34: 139-164. PMID 11092824 DOI: 10.1146/annurev.genet.34.1.139  0.76
2000 Heithoff DM, Sinsheimer RL, Low DA, Mahan MJ. In vivo gene expression and the adaptive response: from pathogenesis to vaccines and antimicrobials. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 355: 633-42. PMID 10874736 DOI: 10.1098/rstb.2000.0604  0.76
2000 Handfield M, Lehoux DE, Sanschagrin F, Mahan MJ, Woods DE, Levesque RC. In vivo-induced genes in Pseudomonas aeruginosa. Infection and Immunity. 68: 2359-62. PMID 10722644 DOI: 10.1128/IAI.68.4.2359-2362.2000  0.76
2000 Julio SM, Heithoff DM, Mahan MJ. ssrA (tmRNA) plays a role in Salmonella enterica serovar Typhimurium pathogenesis. Journal of Bacteriology. 182: 1558-63. PMID 10692360 DOI: 10.1128/JB.182.6.1558-1563.2000  0.76
1999 Heithoff DM, Sinsheimer RL, Low DA, Mahan MJ. An essential role for DNA adenine methylation in bacterial virulence. Science (New York, N.Y.). 284: 967-70. PMID 10320378 DOI: 10.1126/science.284.5416.967  0.76
1999 Heithoff DM, Conner CP, Hentschel U, Govantes F, Hanna PC, Mahan MJ. Coordinate intracellular expression of Salmonella genes induced during infection Journal of Bacteriology. 181: 799-807. PMID 9922242  0.76
1998 Julio SM, Conner CP, Heithoff DM, Mahan MJ. Directed formation of chromosomal deletions in Salmonella typhimurium: targeting of specific genes induced during infection. Molecular & General Genetics : Mgg. 258: 178-81. PMID 9613587 DOI: 10.1007/s004380050721  0.76
1998 Conner CP, Heithoff DM, Julio SM, Sinsheimer RL, Mahan MJ. Differential patterns of acquired virulence genes distinguish Salmonella strains. Proceedings of the National Academy of Sciences of the United States of America. 95: 4641-5. PMID 9539791 DOI: 10.1073/pnas.95.8.4641  0.76
1998 Handfield M, Schweizer HP, Mahan MJ, Sanschagrin F, Hoang T, Levesque RC. ASD-GFP vectors for in vivo expression technology in Pseudomonas aeruginosa and other gram-negative bacteria Biotechniques. 24: 261-264. PMID 9494727  0.76
1997 Heithoff DM, Conner CP, Mahan MJ. Dissecting the biology of a pathogen during infection Trends in Microbiology. 5: 509-512. PMID 9447664 DOI: 10.1016/S0966-842X(97)01153-0  0.76
1997 Conner CP, Heithoff DM, Mahan MJ. In vivo gene expression: Contributions to infection, virulence, and pathogenesis Current Topics in Microbiology and Immunology. 225: 1-12. PMID 9386325  0.76
1997 Rainey PB, Heithoff DM, Mahan MJ. Single-step conjugative cloning of bacterial gene fusions involved in microbe-host interactions. Molecular & General Genetics : Mgg. 256: 84-7. PMID 9341682 DOI: 10.1007/s004380050548  0.76
1997 Heithoff DM, Conner CP, Hanna PC, Julio SM, Hentschel U, Mahan MJ. Bacterial infection as assessed by in vivo gene expression. Proceedings of the National Academy of Sciences of the United States of America. 94: 934-9. PMID 9023360 DOI: 10.1073/pnas.94.3.934  0.76
1996 Slauch JM, Lee AA, Mahan MJ, Mekalanos JJ. Molecular characterization of the oafA locus responsible for acetylation of Salmonella typhimurium O-antigen: OafA is a member of a family of integral membrane trans-acylases Journal of Bacteriology. 178: 5904-5909. PMID 8830685  0.76
1996 Garzón A, Beuzón CR, Mahan MJ, Casadesús J. recB recJ mutants of Salmonella typhimurium are deficient in transductional recombination, DNA repair and plasmid maintenance Molecular and General Genetics. 250: 570-580. PMID 8676860 DOI: 10.1007/s004380050110  0.76
1995 Mahan MJ, Tobias JW, Slauch JM, Hanna PC, Collier RJ, Mekalanos JJ. Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host. Proceedings of the National Academy of Sciences of the United States of America. 92: 669-73. PMID 7846034 DOI: 10.1073/pnas.92.3.669  0.76
1995 Slauch JM, Mahan MJ, Michetti P, Neutra MR, Mekalanos JJ. Acetylation (O-factor 5) affects the structural and immunological properties of Salmonella typhimurium lipopolysaccharide O antigen Infection and Immunity. 63: 437-441. PMID 7529745  0.76
1994 Slauch JM, Mahan MJ, Mekalanos JJ. In vivo expression technology for selection of bacterial genes specifically induced in host tissues Methods in Enzymology. 235: 481-492. PMID 8057920 DOI: 10.1016/0076-6879(94)35164-3  0.76
1994 Slauch JM, Mahan MJ, Mekalanos JJ. Measurement of transcriptional activity in pathogenic bacteria recovered directly from infected host tissue Biotechniques. 16: 641-642+644. PMID 8024783  0.76
1994 Michetti P, Porta N, Mahan MJ, Slauch JM, Mekalanos JJ, Blum A, Kraehenbuhl JP, Neutra MR. Monoclonal immunoglobulin a prevents adherence and invasion of polarized epithelial cell monolayers by Salmonella typhimurium Gastroenterology. 107: 915-923. PMID 7926481  0.76
1993 Mahan MJ, Slauch JM, Mekalanos JJ. Selection of bacterial virulence genes that are specifically induced in host tissues Science. 259: 686-688. PMID 8430319  0.76
1993 Beattie DT, Mahan MJ, Mekalanos JJ. Repressor binding to a regulatory site in the DNA coding sequence is sufficient to confer transcriptional regulation of the vir-repressed genes (vrg genes) in Bordetella pertussis Journal of Bacteriology. 175: 519-527. PMID 8419298  0.76
1993 Mahan MJ, Garzon A, Casadesus J. Host RecJ is required for growth of P22 erf bacteriophage Journal of Bacteriology. 175: 288-290. PMID 8416903  0.76
1993 Mahan MJ, Slauch JM, Mekalanos JJ. Bacteriophage P22 transduction of integrated plasmids: Single-step cloning of Salmonella typhimurium gene fusions Journal of Bacteriology. 175: 7086-7091. PMID 8226650  0.76
1993 Mahan MJ, Slauch JM, Hanna PC, Camilli A, Tobias JW, Waldor MK, Mekalanos JJ. Selection for bacterial genes that are specifically induced in host tissues: The hunt for virulence factors Infectious Agents and Disease. 2: 263-268. PMID 8173806  0.76
1992 Mahan MJ, Casadesus J, Roth JR. The Salmonella typbimurium RecJ function permits growth of P22 abc phage on recBCD+ hosts Mgg Molecular &Amp; General Genetics. 232: 470-478. PMID 1588916 DOI: 10.1007/BF00266252  0.76
1992 Michetti P, Mahan MJ, Slauch JM, Mekalanos JJ, Neutra MR. Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium Infection and Immunity. 60: 1786-1792. PMID 1373399  0.76
1991 Mahan MJ, Roth JR. Ability of a bacterial chromosome segment to invert is dictated by included material rather than flanking sequence Genetics. 129: 1021-1032. PMID 1783289  0.76
1989 Mahan MJ, Roth JR. Role of reBC function in formation of chromosomal rearrangements: A two-step model for recombination Genetics. 121: 433-443. PMID 2714635  0.76
1989 Mahan MJ, Roth JR. RecB and recC genes of Salmonella typhimurium Journal of Bacteriology. 171: 612-615. PMID 2644211  0.76
1988 Mahan MJ, Roth JR. Reciprocality of recombination events that rearrange the chromosome Genetics. 120: 23-35. PMID 3065138  0.76
1988 Segall A, Mahan MJ, Roth JR. Rearrangement of the bacterial chromosome: Forbidden inversions Science. 241: 1314-1318. PMID 3045970  0.76
1983 Mahan MJ, Csonka LN. Genetic analysis of the proBA genes of Salmonella typhimurium: Physical and genetic analyses of the cloned proB+ A+ genes of Escherichia coli and of a mutant allele that confers proline overproduction and enhanced osmotolerance Journal of Bacteriology. 156: 1249-1262. PMID 6315682  0.76
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