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Carl F. Nathan - Publications

Affiliations: 
Microbiology and Immunology Weill Cornell Medical College, New York, NY, United States 
Area:
Immunology, Microbiology Biology
Website:
https://gradschool.weill.cornell.edu/faculty/carl-nathan
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Year Citation  Score
2021 Zhang H, Hsu HC, Kahne SC, Hara R, Zhan W, Jiang X, Burns-Huang K, Ouellette T, Imaeda T, Okamoto R, Kawasaki M, Michino M, Wong TT, Toita A, Yukawa T, ... ... Nathan CF, et al. Macrocyclic Peptides that Selectively Inhibit the Proteasome. Journal of Medicinal Chemistry. PMID 33949190 DOI: 10.1021/acs.jmedchem.1c00296  0.635
2021 Zhang L, Jiang X, Pfau D, Ling Y, Nathan CF. Type I interferon signaling mediates Mycobacterium tuberculosis-induced macrophage death. The Journal of Experimental Medicine. 218. PMID 33125053 DOI: 10.1084/jem.20200887  0.31
2020 Lopez Quezada L, Smith R, Lupoli TJ, Edoo Z, Li X, Gold B, Roberts J, Ling Y, Park SW, Nguyen Q, Schoenen FJ, Li K, Hugonnet JE, Arthur M, Sacchettini JC, ... Nathan C, et al. Activity-Based Protein Profiling Reveals That Cephalosporins Selectively Active on Non-replicating Bind Multiple Protein Families and Spare Peptidoglycan Transpeptidases. Frontiers in Microbiology. 11: 1248. PMID 32655524 DOI: 10.3389/Fmicb.2020.01248  0.344
2020 Schrader SM, Vaubourgeix J, Nathan C. Biology of antimicrobial resistance and approaches to combat it. Science Translational Medicine. 12. PMID 32581135 DOI: 10.1126/Scitranslmed.Aaz6992  0.305
2020 Bryk R, Mundhra S, Jiang X, Wood M, Pfau D, Weber E, Park S, Zhang L, Wilson C, Van der Westhuyzen R, Street L, Chibale K, Zimmerman M, Dartois V, Pastore N, ... ... Nathan C, et al. Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB. Plos Pathogens. 16: e1008567. PMID 32574211 DOI: 10.1371/Journal.Ppat.1008567  0.432
2019 Mosior J, Bourland R, Soma S, Nathan C, Sacchettini J. Structural Insights into Phosphopantetheinyl Hydrolase PptH from Mycobacterium tuberculosis. Protein Science : a Publication of the Protein Society. PMID 31886928 DOI: 10.1002/Pro.3813  0.346
2019 Zhan W, Hsu HC, Morgan T, Ouellette T, Burns-Huang K, Hara R, Wright AG, Imaeda T, Okamoto R, Sato K, Michino M, Ramjee M, Aso K, Meinke P, Foley M, ... Nathan CF, et al. Selective Phenylimidazole-based Inhibitors of the Mycobacterium tuberculosis Proteasome. Journal of Medicinal Chemistry. PMID 31560200 DOI: 10.1021/Acs.Jmedchem.9B01187  0.426
2019 Lopez Quezada L, Silve S, Kelinske M, Liba A, Diaz Gonzalez C, Kotev M, Goullieux L, Sans S, Roubert C, Lagrange S, Bacqué E, Couturier C, Pellet A, Blanc I, Ferron M, ... ... Nathan C, et al. Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA. Mbio. 10. PMID 31289182 DOI: 10.1128/Mbio.01405-19  0.352
2019 Lopez Quezada L, Li K, McDonald SL, Nguyen Q, Perkowski AJ, Pharr CW, Gold B, Roberts J, McAulay K, Saito K, Somersan Karakaya S, Javidnia PE, Porras de Francisco E, Amieva MM, Dı Az SP, ... ... Nathan C, et al. Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating Mycobacterium tuberculosis. Acs Infectious Diseases. PMID 31184461 DOI: 10.1021/Acsinfecdis.9B00112  0.302
2019 Wu J, Mu R, Sun M, Zhao N, Pan M, Li H, Dong Y, Sun Z, Bai J, Hu M, Nathan CF, Javid B, Liu G. Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in Mycobacterium tuberculosis. Acs Infectious Diseases. PMID 31016962 DOI: 10.1021/Acsinfecdis.8B00325  0.362
2019 Ballinger E, Mosior J, Hartman T, Burns-Huang K, Gold B, Morris R, Goullieux L, Blanc I, Vaubourgeix J, Lagrange S, Fraisse L, Sans S, Couturier C, Bacqué E, Rhee K, ... ... Nathan C, et al. Opposing reactions in coenzyme A metabolism sensitize to enzyme inhibition. Science (New York, N.Y.). 363. PMID 30705156 DOI: 10.1126/Science.Aau8959  0.349
2018 Early J, Ollinger J, Darby C, Alling T, Mullen S, Casey A, Gold B, Ochoada J, Wiernicki T, Masquelin T, Nathan CF, Hipskind P, Parish T. Identification of compounds with pH-dependent bactericidal activity against Mycobacterium tuberculosis. Acs Infectious Diseases. PMID 30501173 DOI: 10.1021/Acsinfecdis.8B00256  0.789
2018 McAulay K, Saito K, Warrier T, Walsh KF, Mathurin LD, Royal-Mardi G, Lee MH, Ocheretina O, Pape JW, Fitzgerald DW, Nathan CF. Differentially Detectable Mycobacterium tuberculosis Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment. Mbio. 9. PMID 30459198 DOI: 10.1128/Mbio.02192-18  0.319
2018 Wu K, Koo J, Jiang X, Chen R, Cohen SN, Nathan C. Correction: Improved Control of Tuberculosis and Activation of Macrophages in Mice Lacking Protein Kinase R. Plos One. 13: e0205424. PMID 30289942 DOI: 10.1371/Journal.Pone.0205424  0.323
2018 Negri A, Javidnia P, Mu R, Zhang X, Vendome J, Gold B, Roberts J, Barman D, Ioerger T, Sacchettini JC, Jiang X, Burns-Huang K, Warrier T, Ling Y, Warren JD, ... ... Nathan CF, et al. Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis. Acs Infectious Diseases. PMID 29465985 DOI: 10.1021/Acsinfecdis.7B00111  0.421
2018 Mundhra S, Bryk R, Hawryluk N, Zhang T, Jiang X, Nathan CF. Evidence for dispensability of protein kinase R in host control of tuberculosis. European Journal of Immunology. PMID 29436711 DOI: 10.1002/Eji.201747180  0.395
2017 Santos RLA, Bai L, Singh PK, Murakami N, Fan H, Zhan W, Zhu Y, Jiang X, Zhang K, Assker JP, Nathan CF, Li H, Azzi J, Lin G. Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes. Nature Communications. 8: 1692. PMID 29167449 DOI: 10.1038/S41467-017-01760-5  0.314
2017 Botella H, Yang G, Ouerfelli O, Ehrt S, Nathan CF, Vaubourgeix J. Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis. Mbio. 8. PMID 28900018 DOI: 10.1128/Mbio.01183-17  0.376
2017 Nathan C. Kunkel Lecture: Fundamental immunodeficiency and its correction. The Journal of Experimental Medicine. PMID 28701368 DOI: 10.1084/Jem.20170637  0.307
2017 Saito K, Warrier T, Somersan-Karakaya S, Kaminski L, Mi J, Jiang X, Park S, Shigyo K, Gold B, Roberts J, Weber E, Jacobs WR, Nathan CF. Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations. Proceedings of the National Academy of Sciences of the United States of America. PMID 28559332 DOI: 10.1073/Pnas.1705385114  0.389
2017 Gold B, Nathan C. Targeting Phenotypically Tolerant Mycobacterium tuberculosis. Microbiology Spectrum. 5. PMID 28233509 DOI: 10.1128/Microbiolspec.Tbtb2-0031-2016  0.417
2017 Totaro KA, Barthelme D, Simpson PT, Jiang X, Lin G, Nathan CF, Sauer RT, Sello JK. Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium tuberculosis Proteasome. Acs Infectious Diseases. 3: 176-181. PMID 28183185 DOI: 10.1021/Acsinfecdis.6B00172  0.415
2016 Gold B, Roberts J, Ling Y, Lopez Quezada L, Glasheen J, Ballinger E, Somersan-Karakaya S, Warrier T, Nathan C. Visualization of the Charcoal Agar Resazurin Assay for Semi-quantitative, Medium-throughput Enumeration of Mycobacteria. Journal of Visualized Experiments : Jove. PMID 28060290 DOI: 10.3791/54690  0.416
2016 Dartois V, Saito K, Warrier T, Nathan C. New Evidence for the Complexity of the Population Structure of Mycobacterium tuberculosis Increases the Diagnostic and Biologic Challenges. American Journal of Respiratory and Critical Care Medicine. 194: 1448-1451. PMID 27976945 DOI: 10.1164/Rccm.201607-1431Ed  0.301
2016 Hsu HC, Singh PK, Fan H, Wang R, Sukenick GD, Nathan CF, Lin G, Li H. Structural basis for the species-selective binding of N,C-capped dipeptides to the Mycobacterium tuberculosis proteasome. Biochemistry. PMID 27976853 DOI: 10.1021/Acs.Biochem.6B01107  0.364
2016 Sula Karreci E, Fan H, Uehara M, Mihali AB, Singh PK, Kurdi AT, Solhjou Z, Riella LV, Ghobrial I, Laragione T, Routray S, Assaker JP, Wang R, Sukenick G, Shi L, ... ... Nathan CF, et al. Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 27956634 DOI: 10.1073/Pnas.1618548114  0.306
2016 Lupoli TJ, Fay A, Adura C, Glickman MS, Nathan CF. Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK. Proceedings of the National Academy of Sciences of the United States of America. PMID 27872278 DOI: 10.1073/Pnas.1617644113  0.35
2016 Nathan C. Macrophages' Choice: Take It In or Keep It Out. Immunity. 45: 710-711. PMID 27760333 DOI: 10.1016/J.Immuni.2016.10.002  0.369
2016 Singh PK, Fan H, Jiang X, Shi L, Nathan CF, Lin G. Immunoproteasome β5i-Selective Dipeptidomimetic Inhibitors. Chemmedchem. PMID 27561172 DOI: 10.1002/Cmdc.201600384  0.312
2016 Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Alemán Resto Y, Alsibaee A, Alzualde A, Andrews KT, Avery SV, Avery VM, Ayong L, Baker M, ... ... Nathan C, et al. Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. Plos Pathogens. 12: e1005763. PMID 27467575 DOI: 10.1371/Journal.Ppat.1005763  0.317
2016 Warrier T, Kapilashrami K, Argyrou A, Ioerger TR, Little D, Murphy KC, Nandakumar M, Park S, Gold B, Mi J, Zhang T, Meiler E, Rees M, Somersan-Karakaya S, Porras-De Francisco E, ... ... Nathan CF, et al. N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27432954 DOI: 10.1073/Pnas.1606590113  0.373
2016 Gold B, Smith R, Nguyen Q, Roberts J, Ling Y, Lopez Quezeda L, Somersan-Karakaya S, Warrier T, Little D, Pingle M, Zhang D, Ballinger E, Zimmerman M, Dartois V, Hanson PR, ... ... Nathan CF, et al. Novel cephalosporins selectively active on non-replicating Mycobacterium tuberculosis. Journal of Medicinal Chemistry. PMID 27144688 DOI: 10.1021/Acs.Jmedchem.5B01833  0.434
2015 Warrier T, Martinez-Hoyos M, Marin-Amieva M, Colmenarejo G, Porras-De Francisco E, Alvarez-Pedraglio AI, Fraile-Gabaldon MT, Torres-Gomez PA, Lopez-Quezada L, Gold B, Roberts J, Ling Y, Somersan-Karakaya S, Little D, Cammack N, ... Nathan C, et al. Identification of Novel Anti-mycobacterial Compounds by Screening a Pharmaceutical Small-Molecule Library against Nonreplicating Mycobacterium tuberculosis. Acs Infectious Diseases. 1: 580-585. PMID 27623055 DOI: 10.1021/Acsinfecdis.5B00025  0.354
2015 Maksymiuk C, Ioerger T, Balakrishnan A, Bryk R, Rhee K, Sacchettini J, Nathan C. Comparison of transposon and deletion mutants in Mycobacterium tuberculosis: The case of rv1248c, encoding 2-hydroxy-3-oxoadipate synthase. Tuberculosis (Edinburgh, Scotland). 95: 689-94. PMID 26547230 DOI: 10.1016/J.Tube.2015.08.009  0.347
2015 Maksymiuk C, Balakrishnan A, Bryk R, Rhee KY, Nathan CF. E1 of α-ketoglutarate dehydrogenase defends Mycobacterium tuberculosis against glutamate anaplerosis and nitroxidative stress. Proceedings of the National Academy of Sciences of the United States of America. 112: E5834-43. PMID 26430237 DOI: 10.1073/Pnas.1510932112  0.342
2015 Gold B, Roberts J, Ling Y, Quezada LL, Glasheen J, Ballinger E, Somersan-Karakaya S, Warrier T, Warren JD, Nathan C. Rapid, Semiquantitative Assay To Discriminate among Compounds with Activity against Replicating or Nonreplicating Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 59: 6521-38. PMID 26239979 DOI: 10.1128/Aac.00803-15  0.383
2015 Zhao N, Sun M, Burns-Huang K, Jiang X, Ling Y, Darby C, Ehrt S, Liu G, Nathan C. Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis. Plos One. 10: e0126211. PMID 25978362 DOI: 10.1371/Journal.Pone.0126211  0.801
2015 Gold B, Warrier T, Nathan C. A multi-stress model for high throughput screening against non-replicating Mycobacterium tuberculosis. Methods in Molecular Biology (Clifton, N.J.). 1285: 293-315. PMID 25779324 DOI: 10.1007/978-1-4939-2450-9_18  0.406
2015 Nathan C, Barry CE. TB drug development: immunology at the table. Immunological Reviews. 264: 308-18. PMID 25703568 DOI: 10.1111/Imr.12275  0.39
2015 Vaubourgeix J, Lin G, Dhar N, Chenouard N, Jiang X, Botella H, Lupoli T, Mariani O, Yang G, Ouerfelli O, Unser M, Schnappinger D, McKinney J, Nathan C. Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells. Cell Host & Microbe. 17: 178-90. PMID 25620549 DOI: 10.1016/J.Chom.2014.12.008  0.377
2015 Zhao N, Darby CM, Small J, Bachovchin DA, Jiang X, Burns-Huang KE, Botella H, Ehrt S, Boger DL, Anderson ED, Cravatt BF, Speers AE, Fernandez-Vega V, Hodder PS, Eberhart C, ... ... Nathan CF, et al. Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis. Acs Chemical Biology. 10: 364-71. PMID 25457457 DOI: 10.1021/Cb500746Z  0.787
2014 Nandakumar M, Nathan C, Rhee KY. Isocitrate lyase mediates broad antibiotic tolerance in Mycobacterium tuberculosis. Nature Communications. 5: 4306. PMID 24978671 DOI: 10.1038/Ncomms5306  0.429
2014 Zheng P, Somersan-Karakaya S, Lu S, Roberts J, Pingle M, Warrier T, Little D, Guo X, Brickner SJ, Nathan CF, Gold B, Liu G. Synthetic calanolides with bactericidal activity against replicating and nonreplicating Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 57: 3755-72. PMID 24694175 DOI: 10.1021/Jm4019228  0.398
2014 Gong Y, Somersan Karakaya S, Guo X, Zheng P, Gold B, Ma Y, Little D, Roberts J, Warrier T, Jiang X, Pingle M, Nathan CF, Liu G. Benzimidazole-based compounds kill Mycobacterium tuberculosis. European Journal of Medicinal Chemistry. 75: 336-53. PMID 24556148 DOI: 10.1016/J.Ejmech.2014.01.039  0.375
2014 Nathan C. Drug-resistant tuberculosis: a new shot on goal. Nature Medicine. 20: 121-3. PMID 24504402 DOI: 10.1038/Nm.3470  0.371
2013 Bryk R, Arango N, Maksymiuk C, Balakrishnan A, Wu YT, Wong CH, Masquelin T, Hipskind P, Lima CD, Nathan C. Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase. Biochemistry. 52: 9375-84. PMID 24251446 DOI: 10.1021/Bi401077F  0.34
2013 Rath P, Huang C, Wang T, Wang T, Li H, Prados-Rosales R, Elemento O, Casadevall A, Nathan CF. Genetic regulation of vesiculogenesis and immunomodulation in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 110: E4790-7. PMID 24248369 DOI: 10.1073/Pnas.1320118110  0.631
2013 Cunningham-Bussel A, Zhang T, Nathan CF. Nitrite produced by Mycobacterium tuberculosis in human macrophages in physiologic oxygen impacts bacterial ATP consumption and gene expression. Proceedings of the National Academy of Sciences of the United States of America. 110: E4256-65. PMID 24145454 DOI: 10.1073/Pnas.1316894110  0.814
2013 Cunningham-Bussel A, Bange FC, Nathan CF. Nitrite impacts the survival of Mycobacterium tuberculosis in response to isoniazid and hydrogen peroxide. Microbiologyopen. 2: 901-11. PMID 24019302 DOI: 10.1002/mbo3.126  0.8
2013 Darby CM, Ingólfsson HI, Jiang X, Shen C, Sun M, Zhao N, Burns K, Liu G, Ehrt S, Warren JD, Andersen OS, Anderson OS, Brickner SJ, Nathan C. Whole cell screen for inhibitors of pH homeostasis in Mycobacterium tuberculosis. Plos One. 8: e68942. PMID 23935911 DOI: 10.1371/Journal.Pone.0068942  0.81
2013 Lin G, Chidawanyika T, Tsu C, Warrier T, Vaubourgeix J, Blackburn C, Gigstad K, Sintchak M, Dick L, Nathan C. N,C-capped dipeptides with selectivity for mycobacterial proteasome over human proteasomes: Role of S3 and S1 binding pockets Journal of the American Chemical Society. 135: 9968-9971. PMID 23782398 DOI: 10.1021/Ja400021X  0.32
2013 Balakrishnan A, Jordan F, Nathan CF. Influence of allosteric regulators on individual steps in the reaction catalyzed by Mycobacterium tuberculosis 2-hydroxy-3-oxoadipate synthase. The Journal of Biological Chemistry. 288: 21688-702. PMID 23760263 DOI: 10.1074/Jbc.M113.465419  0.334
2013 Hou YJ, Banerjee R, Thomas B, Nathan C, García-Sastre A, Ding A, Uccellini MB. SARM is required for neuronal injury and cytokine production in response to central nervous system viral infection. Journal of Immunology (Baltimore, Md. : 1950). 191: 875-83. PMID 23749635 DOI: 10.4049/Jimmunol.1300374  0.329
2013 Nathan C, Cunningham-Bussel A. Beyond oxidative stress: an immunologist's guide to reactive oxygen species. Nature Reviews. Immunology. 13: 349-61. PMID 23618831 DOI: 10.1038/Nri3423  0.782
2013 Shigyo K, Ocheretina O, Merveille YM, Johnson WD, Pape JW, Nathan CF, Fitzgerald DW. Efficacy of nitazoxanide against clinical isolates of Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 57: 2834-7. PMID 23507275 DOI: 10.1128/Aac.02542-12  0.338
2013 Darby CM, Ingólfsson HI, Jiang X, Shen C, Sun M, Zhao N, Burns K, Liu G, Ehrt S, Warren JD, Andersen OS, Brickner SJ, Nathan C. Correction: Whole Cell Screen for Inhibitors of pH Homeostasis in Mycobacterium tuberculosis Plos One. 8. DOI: 10.1371/Annotation/760B5B07-4922-42C4-B33A-162C1E9Ae188  0.796
2012 Gold B, Pingle M, Brickner SJ, Shah N, Roberts J, Rundell M, Bracken WC, Warrier T, Somersan S, Venugopal A, Darby C, Jiang X, Warren JD, Fernandez J, Ouerfelli O, ... ... Nathan CF, et al. Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials. Proceedings of the National Academy of Sciences of the United States of America. 109: 16004-11. PMID 23012453 DOI: 10.1073/Pnas.1214188109  0.788
2012 Nathan C. Fresh approaches to anti-infective therapies. Science Translational Medicine. 4: 140sr2. PMID 22745440 DOI: 10.1126/Scitranslmed.3003081  0.319
2012 Nathan C. Secretory products of macrophages: twenty-five years on. The Journal of Clinical Investigation. 122: 1189-90. PMID 22570864 DOI: 10.1172/Jci62930  0.329
2012 Wu K, Koo J, Jiang X, Chen R, Cohen SN, Nathan C. Improved control of tuberculosis and activation of macrophages in mice lacking protein kinase R. Plos One. 7: e30512. PMID 22359543 DOI: 10.1371/Journal.Pone.0030512  0.451
2011 Banchereau J, Cohn F, Inaba K, Muller B, Mellman I, Nathan C, Nussenzweig M, O'Garra A, Seder B, Schuler G, Sher A. Remembering Ralph Steinman. The Journal of Experimental Medicine. 208: 2343-7. PMID 22216461 DOI: 10.1084/Jem.20112295  0.436
2011 de Carvalho LP, Darby CM, Rhee KY, Nathan C. Nitazoxanide Disrupts Membrane Potential and Intrabacterial pH Homeostasis of Mycobacterium tuberculosis. Acs Medicinal Chemistry Letters. 2: 849-854. PMID 22096616 DOI: 10.1021/Ml200157F  0.794
2011 Vogt G, Nathan C. In vitro differentiation of human macrophages with enhanced antimycobacterial activity. The Journal of Clinical Investigation. 121: 3889-901. PMID 21911939 DOI: 10.1172/Jci57235  0.42
2011 Darby CM, Venugopal A, Ehrt S, Nathan CF. Mycobacterium tuberculosis gene Rv2136c is dispensable for acid resistance and virulence in mice. Tuberculosis (Edinburgh, Scotland). 91: 343-7. PMID 21778115 DOI: 10.1016/J.Tube.2011.06.007  0.8
2011 Bryk R, Wu K, Raimundo BC, Boardman PE, Chao P, Conn GL, Anderson E, Cole JL, Duffy NP, Nathan C, Griffin JH. Identification of new inhibitors of protein kinase R guided by statistical modeling. Bioorganic & Medicinal Chemistry Letters. 21: 4108-14. PMID 21632247 DOI: 10.1016/J.Bmcl.2011.04.149  0.313
2011 Rhee KY, de Carvalho LP, Bryk R, Ehrt S, Marrero J, Park SW, Schnappinger D, Venugopal A, Nathan C. Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends in Microbiology. 19: 307-14. PMID 21561773 DOI: 10.1016/J.Tim.2011.03.008  0.579
2011 Venugopal A, Bryk R, Shi S, Rhee K, Rath P, Schnappinger D, Ehrt S, Nathan C. Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes. Cell Host & Microbe. 9: 21-31. PMID 21238944 DOI: 10.1016/J.Chom.2010.12.004  0.786
2011 Mazloum N, Stegman MA, Croteau DL, Van Houten B, Kwon NS, Ling Y, Dickinson C, Venugopal A, Towheed MA, Nathan C. Identification of a chemical that inhibits the mycobacterial UvrABC complex in nucleotide excision repair. Biochemistry. 50: 1329-35. PMID 21235228 DOI: 10.1021/Bi101674C  0.576
2010 Beaulieu AM, Rath P, Imhof M, Siddall ME, Roberts J, Schnappinger D, Nathan CF. Genome-wide screen for Mycobacterium tuberculosis genes that regulate host immunity. Plos One. 5: e15120. PMID 21170273 DOI: 10.1371/Journal.Pone.0015120  0.807
2010 Seimon TA, Kim MJ, Blumenthal A, Koo J, Ehrt S, Wainwright H, Bekker LG, Kaplan G, Nathan C, Tabas I, Russell DG. Induction of ER stress in macrophages of tuberculosis granulomas. Plos One. 5: e12772. PMID 20856677 DOI: 10.1371/Journal.Pone.0012772  0.385
2010 Lin G, Li D, Chidawanyika T, Nathan C, Li H. Fellutamide B is a potent inhibitor of the Mycobacterium tuberculosis proteasome. Archives of Biochemistry and Biophysics. 501: 214-20. PMID 20558127 DOI: 10.1016/J.Abb.2010.06.009  0.323
2010 Darby CM, Nathan CF. Killing of non-replicating Mycobacterium tuberculosis by 8-hydroxyquinoline. The Journal of Antimicrobial Chemotherapy. 65: 1424-7. PMID 20435781 DOI: 10.1093/Jac/Dkq145  0.797
2010 de Carvalho LP, Zhao H, Dickinson CE, Arango NM, Lima CD, Fischer SM, Ouerfelli O, Nathan C, Rhee KY. Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase. Chemistry & Biology. 17: 323-32. PMID 20416504 DOI: 10.1016/J.Chembiol.2010.03.009  0.306
2010 Bryk R, Arango N, Venugopal A, Warren JD, Park YH, Patel MS, Lima CD, Nathan C. Triazaspirodimethoxybenzoyls as selective inhibitors of mycobacterial lipoamide dehydrogenase . Biochemistry. 49: 1616-27. PMID 20078138 DOI: 10.1021/Bi9016186  0.566
2010 Yin F, Banerjee R, Thomas B, Zhou P, Qian L, Jia T, Ma X, Ma Y, Iadecola C, Beal MF, Nathan C, Ding A. Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice. The Journal of Experimental Medicine. 207: 117-28. PMID 20026663 DOI: 10.1084/Jem.20091568  0.351
2009 Wang T, Li H, Lin G, Tang C, Li D, Nathan C, Darwin KH, Li H. Structural insights on the Mycobacterium tuberculosis proteasomal ATPase Mpa. Structure (London, England : 1993). 17: 1377-85. PMID 19836337 DOI: 10.1016/J.Str.2009.08.010  0.657
2009 Lin G, Li D, de Carvalho LP, Deng H, Tao H, Vogt G, Wu K, Schneider J, Chidawanyika T, Warren JD, Li H, Nathan C. Inhibitors selective for mycobacterial versus human proteasomes. Nature. 461: 621-6. PMID 19759536 DOI: 10.1038/Nature08357  0.396
2009 de Carvalho LP, Lin G, Jiang X, Nathan C. Nitazoxanide kills replicating and nonreplicating Mycobacterium tuberculosis and evades resistance. Journal of Medicinal Chemistry. 52: 5789-92. PMID 19736929 DOI: 10.1021/Jm9010719  0.379
2009 Vandal OH, Nathan CF, Ehrt S. Acid resistance in Mycobacterium tuberculosis. Journal of Bacteriology. 191: 4714-21. PMID 19465648 DOI: 10.1128/Jb.00305-09  0.809
2009 Nathan C. Taming tuberculosis: a challenge for science and society. Cell Host & Microbe. 5: 220-4. PMID 19286131 DOI: 10.1016/J.Chom.2009.02.004  0.332
2009 Lee WL, Gold B, Darby C, Brot N, Jiang X, de Carvalho LP, Wellner D, St John G, Jacobs WR, Nathan C. Mycobacterium tuberculosis expresses methionine sulphoxide reductases A and B that protect from killing by nitrite and hypochlorite. Molecular Microbiology. 71: 583-93. PMID 19040639 DOI: 10.1111/J.1365-2958.2008.06548.X  0.806
2009 Vandal OH, Roberts JA, Odaira T, Schnappinger D, Nathan CF, Ehrt S. Acid-susceptible mutants of Mycobacterium tuberculosis share hypersusceptibility to cell wall and oxidative stress and to the host environment. Journal of Bacteriology. 191: 625-31. PMID 19011036 DOI: 10.1128/Jb.00932-08  0.812
2008 Nathan C. Microbiology. An antibiotic mimics immunity. Science (New York, N.Y.). 322: 1337-8. PMID 19039126 DOI: 10.1126/Science.1167452  0.309
2008 Lin G, Tsu C, Dick L, Zhou XK, Nathan C. Distinct specificities of Mycobacterium tuberculosis and mammalian proteasomes for N-acetyl tripeptide substrates. The Journal of Biological Chemistry. 283: 34423-31. PMID 18829465 DOI: 10.1074/Jbc.M805324200  0.342
2008 Nathan C, Gold B, Lin G, Stegman M, de Carvalho LP, Vandal O, Venugopal A, Bryk R. A philosophy of anti-infectives as a guide in the search for new drugs for tuberculosis. Tuberculosis (Edinburgh, Scotland). 88: S25-33. PMID 18762150 DOI: 10.1016/S1472-9792(08)70034-9  0.798
2008 Gold B, Deng H, Bryk R, Vargas D, Eliezer D, Roberts J, Jiang X, Nathan C. Identification of a copper-binding metallothionein in pathogenic mycobacteria. Nature Chemical Biology. 4: 609-16. PMID 18724363 DOI: 10.1038/Nchembio.109  0.355
2008 Vandal OH, Pierini LM, Schnappinger D, Nathan CF, Ehrt S. A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis. Nature Medicine. 14: 849-54. PMID 18641659 DOI: 10.1038/Nm.1795  0.804
2008 Bryk R, Gold B, Venugopal A, Singh J, Samy R, Pupek K, Cao H, Popescu C, Gurney M, Hotha S, Cherian J, Rhee K, Ly L, Converse PJ, Ehrt S, ... ... Nathan C, et al. Selective killing of nonreplicating mycobacteria. Cell Host & Microbe. 3: 137-45. PMID 18329613 DOI: 10.1016/J.Chom.2008.02.003  0.815
2007 Kim Y, Zhou P, Qian L, Chuang JZ, Lee J, Li C, Iadecola C, Nathan C, Ding A. MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival. The Journal of Experimental Medicine. 204: 2063-74. PMID 17724133 DOI: 10.1084/Jem.20070868  0.308
2006 Nathan C. Neutrophils and immunity: challenges and opportunities. Nature Reviews. Immunology. 6: 173-82. PMID 16498448 DOI: 10.1038/Nri1785  0.315
2006 Vandal OH, Gelb MH, Ehrt S, Nathan CF. Cytosolic phospholipase A2 enzymes are not required by mouse bone marrow-derived macrophages for the control of Mycobacterium tuberculosis in vitro. Infection and Immunity. 74: 1751-6. PMID 16495548 DOI: 10.1128/Iai.74.3.1751-1756.2006  0.812
2006 Hu G, Lin G, Wang M, Dick L, Xu RM, Nathan C, Li H. Structure of the Mycobacterium tuberculosis proteasome and mechanism of inhibition by a peptidyl boronate. Molecular Microbiology. 59: 1417-28. PMID 16468986 DOI: 10.1111/J.1365-2958.2005.05036.X  0.329
2006 Lin G, Hu G, Tsu C, Kunes YZ, Li H, Dick L, Parsons T, Li P, Chen Z, Zwickl P, Weich N, Nathan C. Mycobacterium tuberculosis prcBA genes encode a gated proteasome with broad oligopeptide specificity. Molecular Microbiology. 59: 1405-16. PMID 16468985 DOI: 10.1111/J.1365-2958.2005.05035.X  0.313
2006 Cohn EF, Nathan C, Radzioch D, Yu H, Xiang Z, Ding A. Abrupt expression of TLR4 in TLR4-deficient macrophages imposes a selective disadvantage: genetic evidence for TLR4-dependent responses to endogenous, nonmicrobial stimuli. Journal of Immunology (Baltimore, Md. : 1950). 176: 1185-94. PMID 16394008 DOI: 10.4049/Jimmunol.176.2.1185  0.339
2006 Han H, Roberts J, Lou O, Muller WA, Nathan N, Nathan C. Chemical inhibitors of TNF signal transduction in human neutrophils point to distinct steps in cell activation. Journal of Leukocyte Biology. 79: 147-54. PMID 16275893 DOI: 10.1189/Jlb.0605308  0.625
2005 Smith I, Nathan C, Peavy HH. Progress and new directions in genetics of tuberculosis: an NHLBI working group report. American Journal of Respiratory and Critical Care Medicine. 172: 1491-6. PMID 16192449 DOI: 10.1164/Rccm.200506-997Ws  0.373
2005 Rajashankar KR, Bryk R, Kniewel R, Buglino JA, Nathan CF, Lima CD. Crystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosis. The Journal of Biological Chemistry. 280: 33977-83. PMID 16093239 DOI: 10.1074/Jbc.M507466200  0.346
2005 Tian J, Bryk R, Shi S, Erdjument-Bromage H, Tempst P, Nathan C. Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes. Molecular Microbiology. 57: 859-68. PMID 16045627 DOI: 10.1111/J.1365-2958.2005.04741.X  0.655
2005 Han H, Stessin A, Roberts J, Hess K, Gautam N, Kamenetsky M, Lou O, Hyde E, Nathan N, Muller WA, Buck J, Levin LR, Nathan C. Calcium-sensing soluble adenylyl cyclase mediates TNF signal transduction in human neutrophils. The Journal of Experimental Medicine. 202: 353-61. PMID 16043520 DOI: 10.1084/Jem.20050778  0.622
2005 Darwin KH, Nathan CF. Role for nucleotide excision repair in virulence of Mycobacterium tuberculosis. Infection and Immunity. 73: 4581-7. PMID 16040969 DOI: 10.1128/Iai.73.8.4581-4587.2005  0.675
2005 Tian J, Bryk R, Itoh M, Suematsu M, Nathan C. Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: identification of alpha-ketoglutarate decarboxylase. Proceedings of the National Academy of Sciences of the United States of America. 102: 10670-5. PMID 16027371 DOI: 10.1073/Pnas.0501605102  0.487
2005 Kaufmann SH, Cole ST, Mizrahi V, Rubin E, Nathan C. Mycobacterium tuberculosis and the host response. The Journal of Experimental Medicine. 201: 1693-7. PMID 15939785 DOI: 10.1084/Jem.20050842  0.376
2005 Hisert KB, MacCoss M, Shiloh MU, Darwin KH, Singh S, Jones RA, Ehrt S, Zhang Z, Gaffney BL, Gandotra S, Holden DW, Murray D, Nathan C. A glutamate-alanine-leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP. Molecular Microbiology. 56: 1234-45. PMID 15882417 DOI: 10.1111/J.1365-2958.2005.04632.X  0.785
2005 Darwin KH, Lin G, Chen Z, Li H, Nathan CF. Characterization of a Mycobacterium tuberculosis proteasomal ATPase homologue. Molecular Microbiology. 55: 561-71. PMID 15659170 DOI: 10.1111/J.1365-2958.2004.04403.X  0.678
2005 Rhee KY, Erdjument-Bromage H, Tempst P, Nathan CF. S-nitroso proteome of Mycobacterium tuberculosis: Enzymes of intermediary metabolism and antioxidant defense. Proceedings of the National Academy of Sciences of the United States of America. 102: 467-72. PMID 15626759 DOI: 10.1073/Pnas.0406133102  0.371
2004 Nathan C. The moving frontier in nitric oxide-dependent signaling. Science's Stke : Signal Transduction Knowledge Environment. 2004: pe52. PMID 15523044 DOI: 10.1126/Stke.2572004Pe52  0.326
2004 Hisert KB, Kirksey MA, Gomez JE, Sousa AO, Cox JS, Jacobs WR, Nathan CF, McKinney JD. Identification of Mycobacterium tuberculosis counterimmune (cim) mutants in immunodeficient mice by differential screening. Infection and Immunity. 72: 5315-21. PMID 15322028 DOI: 10.1128/Iai.72.9.5315-5321.2004  0.7
2003 Darwin KH, Ehrt S, Gutierrez-Ramos JC, Weich N, Nathan CF. The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide. Science (New York, N.Y.). 302: 1963-6. PMID 14671303 DOI: 10.1126/Science.1091176  0.691
2003 Shi S, Nathan C, Schnappinger D, Drenkow J, Fuortes M, Block E, Ding A, Gingeras TR, Schoolnik G, Akira S, Takeda K, Ehrt S. MyD88 primes macrophages for full-scale activation by interferon-gamma yet mediates few responses to Mycobacterium tuberculosis. The Journal of Experimental Medicine. 198: 987-97. PMID 14517275 DOI: 10.1084/Jem.20030603  0.779
2003 Schnappinger D, Ehrt S, Voskuil MI, Liu Y, Mangan JA, Monahan IM, Dolganov G, Efron B, Butcher PD, Nathan C, Schoolnik GK. Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment. The Journal of Experimental Medicine. 198: 693-704. PMID 12953091 DOI: 10.1084/Jem.20030846  0.431
2003 Nathan C. Immunology: Oxygen and the inflammatory cell. Nature. 422: 675-6. PMID 12700748 DOI: 10.1038/422675A  0.344
2003 Han H, Fuortes M, Nathan C. Critical role of the carboxyl terminus of proline-rich tyrosine kinase (Pyk2) in the activation of human neutrophils by tumor necrosis factor: separation of signals for the respiratory burst and degranulation. The Journal of Experimental Medicine. 197: 63-75. PMID 12515814 DOI: 10.1084/Jem.20021638  0.618
2002 Zhu J, Nathan C, Jin W, Sim D, Ashcroft GS, Wahl SM, Lacomis L, Erdjument-Bromage H, Tempst P, Wright CD, Ding A. Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair. Cell. 111: 867-78. PMID 12526812 DOI: 10.1016/S0092-8674(02)01141-8  0.344
2002 Nathan C. Immunology. Catalytic antibody bridges innate and adaptive immunity. Science (New York, N.Y.). 298: 2143-4. PMID 12481124 DOI: 10.1126/Science.1080005  0.308
2002 Bryk R, Lima CD, Erdjument-Bromage H, Tempst P, Nathan C. Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein Science. 295: 1073-1077. PMID 11799204 DOI: 10.1126/Science.1067798  0.373
2002 Weissbach H, Etienne F, Hoshi T, Heinemann SH, Lowther WT, Matthews B, St John G, Nathan C, Brot N. Peptide methionine sulfoxide reductase: structure, mechanism of action, and biological function. Archives of Biochemistry and Biophysics. 397: 172-8. PMID 11795868 DOI: 10.1006/Abbi.2001.2664  0.315
2001 Ehrt S, Schnappinger D, Bekiranov S, Drenkow J, Shi S, Gingeras TR, Gaasterland T, Schoolnik G, Nathan C. Reprogramming of the macrophage transcriptome in response to interferon-gamma and Mycobacterium tuberculosis: signaling roles of nitric oxide synthase-2 and phagocyte oxidase. The Journal of Experimental Medicine. 194: 1123-40. PMID 11602641 DOI: 10.1084/Jem.194.8.1123  0.64
2001 Hickman-Davis JM, Fang FC, Nathan C, Shepherd VL, Voelker DR, Wright JR. Lung surfactant and reactive oxygen-nitrogen species: Antimicrobial activity and host-pathogen interactions American Journal of Physiology - Lung Cellular and Molecular Physiology. 281. PMID 11504674 DOI: 10.1152/Ajplung.2001.281.3.L517  0.35
2001 St. John G, Brot N, Ruan J, Erdjument-Bromage H, Tempst P, Weissbach H, Nathan C. Peptide methionine sulfoxide reductase from Escherichia coli and Mycobacterium tuberculosis protects bacteria against oxidative damage from reactive nitrogen intermediates Proceedings of the National Academy of Sciences of the United States of America. 98: 9901-9906. PMID 11481433 DOI: 10.1073/Pnas.161295398  0.419
2001 Nathan C, Ding A. TREM-1: A new regulator of innate immunity in sepsis syndrome Nature Medicine. 7: 530-532. PMID 11329047 DOI: 10.1038/87846  0.309
2000 Bryk R, Griffin P, Nathan C. Peroxynitrite reductase activity of bacterial peroxiredoxins Nature. 407: 211-215. PMID 11001062 DOI: 10.1038/35025109  0.38
2000 Nathan C, Shiloh MU. Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens. Proceedings of the National Academy of Sciences of the United States of America. 97: 8841-8. PMID 10922044 DOI: 10.1073/Pnas.97.16.8841  0.735
2000 Grobmyer SR, Barie PS, Nathan CF, Fuortes M, Lin E, Lowry SF, Wright CD, Weyant MJ, Hydo L, Reeves F, Shiloh MU, Ding A. Secretory leukocyte protease inhibitor, an inhibitor of neutrophil activation, is elevated in serum in human sepsis and experimental endotoxemia. Critical Care Medicine. 28: 1276-82. PMID 10834665 DOI: 10.1097/00003246-200005000-00003  0.668
2000 Shiloh MU, Nathan CF. Reactive nitrogen intermediates and the pathogenesis of Salmonella and mycobacteria. Current Opinion in Microbiology. 3: 35-42. PMID 10679417 DOI: 10.1016/S1369-5274(99)00048-X  0.736
1999 Zhu J, Nathan C, Ding A. Suppression of macrophage responses to bacterial lipopolysaccharide by a non-secretory form of secretory leukocyte protease inhibitor Biochimica Et Biophysica Acta - Molecular Cell Research. 1451: 219-223. PMID 10556576 DOI: 10.1016/S0167-4889(99)00111-1  0.369
1999 Nicholson SC, Hahn RT, Grobmyer SR, Brause JE, Hafner A, Potter S, Devereux RB, Nathan CF. Echocardiographic and survival studies in mice undergoing endotoxic shock: effects of genetic ablation of inducible nitric oxide synthase and pharmacologic antagonism of platelet-activating factor. The Journal of Surgical Research. 86: 198-205. PMID 10534424 DOI: 10.1006/Jsre.1999.5715  0.327
1999 Fuortes M, Melchior M, Han H, Lyon GJ, Nathan C. Role of the tyrosine kinase pyk2 in the integrin-dependent activation of human neutrophils by TNF. The Journal of Clinical Investigation. 104: 327-35. PMID 10430614 DOI: 10.1172/Jci6018  0.594
1999 Ruan J, St John G, Ehrt S, Riley L, Nathan C. noxR3, a novel gene from Mycobacterium tuberculosis, protects Salmonella typhimurium from nitrosative and oxidative stress. Infection and Immunity. 67: 3276-83. PMID 10377101 DOI: 10.1128/Iai.67.7.3276-3283.1999  0.45
1999 Byrd CA, Bornmann W, Erdjument-Bromage H, Tempst P, Pavletich N, Rosen N, Nathan CF, Ding A. Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide. Proceedings of the National Academy of Sciences of the United States of America. 96: 5645-50. PMID 10318938 DOI: 10.1073/Pnas.96.10.5645  0.334
1999 Nicholson SC, Grobmyer SR, Shiloh MU, Brause JE, Potter S, MacMicking JD, Dinauer MC, Nathan CF. Lethality of endotoxin in mice genetically deficient in the respiratory burst oxidase, inducible nitric oxide synthase, or both. Shock (Augusta, Ga.). 11: 253-8. PMID 10220301 DOI: 10.1097/00024382-199904000-00005  0.713
1999 Shiloh MU, MacMicking JD, Nicholson S, Brause JE, Potter S, Marino M, Fang F, Dinauer M, Nathan C. Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase. Immunity. 10: 29-38. PMID 10023768 DOI: 10.1016/S1074-7613(00)80004-7  0.738
1999 Murray HW, Nathan CF. Macrophage microbicidal mechanisms in vivo: reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani. The Journal of Experimental Medicine. 189: 741-6. PMID 9989990 DOI: 10.1084/Jem.189.4.741  0.361
1999 Ding A, Zhu J, Jin F, Grobmyer SR, Nathan CF. Anti-inflammatory function of secretory leukocyte protease inhibitor Journal of Endotoxin Research. 5: 167-169. DOI: 10.1177/09680519990050031201  0.351
1999 Grobmyer S, Barie P, Nathan C, Fuortes M, Lin E, Lowry S, Wright C, Wevant M, Hydo L, Reeves F, Shiloh M, Ding A. SECRETORY LEUKOCYTE PROTEASE INHIBITOR, AN INHIBITOR OF NEUTROPHIL ACTIVATION, IS ELEVATED IN SERUM IN HUMAN SEPSIS AND CORRELATES WITH SEVERITY OF ORGAN DYSFUNCTION Shock. 11: 45. DOI: 10.1097/00024382-199906001-00158  0.671
1999 Shiloh MU, Nathan CF. Antimicrobial mechanisms of macrophages Advances in Cellular and Molecular Biology of Membranes and Organelles. 5: 407-439. DOI: 10.1016/S1874-5172(99)80042-X  0.723
1998 Jin F, Nathan C, Ding A. Identification of genes involved in innate responsiveness to bacterial products by differential display Methods: a Companion to Methods in Enzymology. 16: 396-406. PMID 10049647 DOI: 10.1006/Meth.1998.0694  0.339
1998 Karupiah G, Chen JH, Mahalingam S, Nathan CF, MacMicking JD. Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. The Journal of Experimental Medicine. 188: 1541-6. PMID 9782132 DOI: 10.1084/Jem.188.8.1541  0.326
1998 Bonecini-Almeida MG, Silva JRLE, Kritski AL, Neves I, Morgado MG, Nathan C, Ho JL. Immune Response During HIV and Tuberculosis Co-infection Memorias Do Instituto Oswaldo Cruz. 93: 399-402. PMID 9698876 DOI: 10.1590/S0074-02761998000300023  0.321
1998 Karupiah G, Chen JH, Nathan CF, Mahalingam S, MacMicking JD. Identification of nitric oxide synthase 2 as an innate resistance locus against ectromelia virus infection. Journal of Virology. 72: 7703-6. PMID 9696880 DOI: 10.1128/Jvi.72.9.7703-7706.1998  0.386
1998 Chen L, Xie QW, Nathan C. Alkyl hydroperoxide reductase subunit C (AhpC) protects bacterial and human cells against reactive nitrogen intermediates Molecular Cell. 1: 795-805. PMID 9660963 DOI: 10.1016/S1097-2765(00)80079-9  0.411
1998 Jin F, Nathan CF, Radzioch D, Ding A. Lipopolysaccharide-related stimuli induce expression of the secretory leukocyte protease inhibitor, a macrophage-derived lipopolysaccharide inhibitor. Infection and Immunity. 66: 2447-52. PMID 9596701 DOI: 10.1128/Iai.66.6.2447-2452.1998  0.344
1998 Hierholzer C, Harbrecht B, Menezes JM, Kane J, MacMicking J, Nathan CF, Peitzman AB, Billiar TR, Tweardy DJ. Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock. The Journal of Experimental Medicine. 187: 917-28. PMID 9500794 DOI: 10.1084/Jem.187.6.917  0.33
1997 De Groote MA, Ochsner UA, Shiloh MU, Nathan C, McCord JM, Dinauer MC, Libby SJ, Vazquez-Torres A, Xu Y, Fang FC. Periplasmic superoxide dismutase protects Salmonella from products of phagocyte NADPH-oxidase and nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 94: 13997-4001. PMID 9391141 DOI: 10.1073/Pnas.94.25.13997  0.713
1997 Ehrt S, Shiloh MU, Ruan J, Choi M, Gunzburg S, Nathan C, Xie Q, Riley LW. A novel antioxidant gene from Mycobacterium tuberculosis. The Journal of Experimental Medicine. 186: 1885-96. PMID 9382887 DOI: 10.1084/Jem.186.11.1885  0.752
1997 Nathan C. Inducible nitric oxide synthase: What difference does it make? Journal of Clinical Investigation. 100: 2417-2423. PMID 9366554 DOI: 10.1172/Jci119782  0.307
1997 Hickey MJ, Sharkey KA, Sihota EG, Reinhardt PH, Macmicking JD, Nathan C, Kubes P. Inducible nitric oxide synthase-deficient mice have enhanced leukocyte-endothelium interactions in endotoxemia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 11: 955-64. PMID 9337148 DOI: 10.1096/Fasebj.11.12.9337148  0.345
1997 Shiloh MU, Ruan J, Nathan C. Evaluation of bacterial survival and phagocyte function with a fluorescence-based microplate assay. Infection and Immunity. 65: 3193-8. PMID 9234774 DOI: 10.1128/Iai.65.8.3193-3198.1997  0.714
1997 MacMicking JD, North RJ, LaCourse R, Mudgett JS, Shah SK, Nathan CF. Identification of nitric oxide synthase as a protective locus against tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 94: 5243-8. PMID 9144222 DOI: 10.1073/Pnas.94.10.5243  0.443
1997 MacMicking J, Xie QW, Nathan C. Nitric oxide and macrophage function Annual Review of Immunology. 15: 323-350. PMID 9143691 DOI: 10.1146/Annurev.Immunol.15.1.323  0.437
1997 Jin FY, Nathan C, Radzioch D, Ding A. Secretory leukocyte protease inhibitor: A macrophage product induced by and antagonistic to bacterial lipopolysaccharide Cell. 88: 417-426. PMID 9039268 DOI: 10.1016/S0092-8674(00)81880-2  0.337
1997 Wheeler MA, Smith SD, García-Cardeña G, Nathan CF, Weiss RM, Sessa WC. Bacterial infection induces nitric oxide synthase in human neutrophils. The Journal of Clinical Investigation. 99: 110-6. PMID 9011564 DOI: 10.1172/Jci119121  0.365
1996 Nicholson S, Bonecini-Almeida Mda G, Lapa e Silva JR, Nathan C, Xie QW, Mumford R, Weidner JR, Calaycay J, Geng J, Boechat N, Linhares C, Rom W, Ho JL. Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis. The Journal of Experimental Medicine. 183: 2293-302. PMID 8642338 DOI: 10.1084/Jem.183.5.2293  0.44
1996 Fuortes M, Jin WW, Nathan C. Ceramide selectively inhibits early events in the response of human neutrophils to tumor necrosis factor Journal of Leukocyte Biology. 59: 451-460. PMID 8604026 DOI: 10.1002/Jlb.59.3.451  0.306
1996 Cho HJ, Martin E, Xie QW, Sassa S, Nathan C. Inducible nitric oxide synthase: identification of amino acid residues essential for dimerization and binding of tetrahydrobiopterin. Proceedings of the National Academy of Sciences of the United States of America. 92: 11514-8. PMID 8524794 DOI: 10.1073/Pnas.92.25.11514  0.303
1995 Nathan C. Natural resistance and nitric oxide Cell. 82: 873-876. PMID 7553846 DOI: 10.1016/0092-8674(95)90019-5  0.314
1995 Maciejewski JP, Selleri C, Sato T, Cho HJ, Keefer LK, Nathan CF, Young NS. Nitric oxide suppression of human hematopoiesis in vitro. Contribution to inhibitory action of interferon-gamma and tumor necrosis factor-alpha. The Journal of Clinical Investigation. 96: 1085-92. PMID 7543491 DOI: 10.1172/Jci118094  0.333
1995 Nathan C. Inducible nitric oxide synthase: Regulation subserves function Current Topics in Microbiology and Immunology. 196: 1-4. PMID 7543397 DOI: 10.1007/978-3-642-79130-7_1  0.304
1995 MacMicking JD, Nathan C, Hom G, Chartrain N, Fletcher DS, Trumbauer M, Stevens K, Xie QW, Sokol K, Hutchinson N. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell. 81: 641-50. PMID 7538909 DOI: 10.1016/0092-8674(95)90085-3  0.343
1994 Celada A, Nathan C. Macrophage activation revisited Immunology Today. 15: 100-102. PMID 7909663 DOI: 10.1016/0167-5699(94)90150-3  0.314
1994 Sparrow JR, Nathan C, Vodovotz Y. Cytokine regulation of nitric oxide synthase in mouse retinal pigment epithelial cells in culture Experimental Eye Research. 59: 129-139. PMID 7530664 DOI: 10.1006/Exer.1994.1091  0.351
1994 Xie QW, Nathan C. The high-output nitric oxide pathway: Role and regulation Journal of Leukocyte Biology. 56: 576-582. PMID 7525816 DOI: 10.1002/Jlb.56.5.576  0.352
1994 Nathan C, Xie Qw. Nitric oxide synthases: Roles, tolls, and controls Cell. 78: 915-918. PMID 7522969 DOI: 10.1016/0092-8674(94)90266-6  0.309
1994 Martin E, Nathan C, Xie QW. Role of interferon regulatory factor 1 in induction of nitric oxide synthase Journal of Experimental Medicine. 180: 977-984. PMID 7520478 DOI: 10.1084/Jem.180.3.977  0.348
1994 Bogdan C, Vodovotz Y, Paik J, Xie QW, Nathan C. Mechanism of suppression of nitric oxide synthase expression by interleukin-4 in primary mouse macrophages. Journal of Leukocyte Biology. 55: 227-33. PMID 7507968 DOI: 10.1002/Jlb.55.2.227  0.367
1993 Klebanoff SJ, Nathan CF. Nitrite production by stimulated human polymorphonuclear leukocytes supplemented with azide and catalase Biochemical and Biophysical Research Communications. 197: 192-196. PMID 8250925 DOI: 10.1006/Bbrc.1993.2459  0.317
1993 Karupiah G, Xie QW, Buller RM, Nathan C, Duarte C, MacMicking JD. Inhibition of viral replication by interferon-gamma-induced nitric oxide synthase. Science (New York, N.Y.). 261: 1445-8. PMID 7690156 DOI: 10.1126/Science.7690156  0.368
1993 McCartney-Francis N, Allen JB, Mizel DE, Albina JE, Xie QW, Nathan CF, Wahl SM. Suppression of arthritis by an inhibitor of nitric oxide synthase. The Journal of Experimental Medicine. 178: 749-54. PMID 7688035 DOI: 10.1084/Jem.178.2.749  0.345
1993 Xie QW, Whisnant R, Nathan C. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon γ and bacterial lipopolysaccharide Journal of Experimental Medicine. 177: 1779-1784. PMID 7684434 DOI: 10.1084/Jem.177.6.1779  0.354
1992 Nathan C. Nitric oxide as a secretory product of mammalian cells Faseb Journal. 6: 3051-3064. PMID 1381691 DOI: 10.1096/Fasebj.6.12.1381691  0.316
1992 Cho HJ, Xie QW, Calaycay J, Mumford RA, Swiderek KM, Lee TD, Nathan C. Calmodulin is a subunit of nitric oxide synthase from macrophages. The Journal of Experimental Medicine. 176: 599-604. PMID 1380065 DOI: 10.1084/Jem.176.2.599  0.324
1992 Xie QW, Cho HJ, Calaycay J, Mumford RA, Swiderek KM, Lee TD, Ding A, Troso T, Nathan C. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science (New York, N.Y.). 256: 225-8. PMID 1373522 DOI: 10.1126/Science.1373522  0.403
1991 Nathan C. A commentary: inducible nitric oxide synthase Research in Immunology. 142: 600-602. PMID 1725935 DOI: 10.1016/0923-2494(91)90117-2  0.308
1991 Kwon NS, Stuehr DJ, Nathan CF. Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide Journal of Experimental Medicine. 174: 761-767. PMID 1717630 DOI: 10.1084/Jem.174.4.761  0.37
1991 Stuehr DJ, Cho HJ, Kwon NS, Weise MF, Nathan CF. Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein. Proceedings of the National Academy of Sciences of the United States of America. 88: 7773-7. PMID 1715579 DOI: 10.1073/Pnas.88.17.7773  0.365
1991 Nathan CF, Hibbs JB. Role of nitric oxide synthesis in macrophage antimicrobial activity. Current Opinion in Immunology. 3: 65-70. PMID 1711326 DOI: 10.1016/0952-7915(91)90079-G  0.391
1991 Stuehr DJ, Fasehun OA, Kwon NS, Gross SS, Gonzalez JA, Levi R, Nathan CF. Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 98-103. PMID 1703974 DOI: 10.1096/Fasebj.5.1.1703974  0.382
1990 Porteu F, Nathan C. Shedding of tumor necrosis factor receptors by activated human neutrophils Journal of Experimental Medicine. 172: 599-607. PMID 2165128 DOI: 10.1084/Jem.172.2.599  0.304
1990 Srimal S, Nathan C. Purification of macrophage deactivating factor Journal of Experimental Medicine. 171: 1347-1361. PMID 2109038 DOI: 10.1084/Jem.171.4.1347  0.323
1990 Stuehr DJ, Kwon NS, Nathan CF. FAD and GSH participate in macrophage synthesis of nitric oxide Biochemical and Biophysical Research Communications. 168: 558-565. PMID 1692211 DOI: 10.1016/0006-291X(90)92357-6  0.355
1990 Nathan CF, Stuehr DJ. Does endothelium-derived nitric oxide have a rolein cytokine-induced hypotension? Journal of the National Cancer Institute. 82: 726-728. PMID 1691302 DOI: 10.1093/Jnci/82.9.726  0.317
1989 Stuehr DJ, Gross SS, Sakuma I, Levi R, Nathan CF. Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide. The Journal of Experimental Medicine. 169: 1011-20. PMID 2784476 DOI: 10.1084/Jem.169.3.1011  0.384
1989 Stuehr DJ, Kwon NS, Gross SS, Thiel BA, Levi R, Nathan CF. Synthesis of nitrogen oxides from L-arginine by macrophage cytosol: requirement for inducible and constitutive components. Biochemical and Biophysical Research Communications. 161: 420-6. PMID 2735902 DOI: 10.1016/0006-291X(89)92615-6  0.399
1989 Gabay JE, Scott RW, Campanelli D, Griffith J, Wilde C, Marra MN, Seeger M, Nathan CF. Antibiotic proteins of human polymorphonuclear leukocytes. Proceedings of the National Academy of Sciences of the United States of America. 86: 5610-4. PMID 2501794 DOI: 10.1073/Pnas.86.14.5610  0.301
1989 Stuehr DJ, Nathan CF. Nitric oxide: A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells Journal of Experimental Medicine. 169: 1543-1555. PMID 2497225 DOI: 10.1084/Jem.169.5.1543  0.339
1988 Wolpe SD, Davatelis G, Sherry B, Beutler B, Hesse DG, Nguyen HT, Moldawer LL, Nathan CF, Lowry SF, Cerami A. Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties. The Journal of Experimental Medicine. 167: 570-81. PMID 3279154 DOI: 10.1084/Jem.167.2.570  0.365
1988 Sakuma I, Stuehr DJ, Gross SS, Nathan C, Levi R. Identification of arginine as a precursor of endothelium-derived relaxing factor Proceedings of the National Academy of Sciences of the United States of America. 85: 8664-8667. PMID 3263652 DOI: 10.1073/Pnas.85.22.8664  0.302
1988 Murray HW, Nathan CF. In vivo killing of intracellular visceral leishmania donovani by a macrophage-targeted hydrogen peroxide-generating system Journal of Infectious Diseases. 158: 1372-1375. PMID 3198943 DOI: 10.1093/Infdis/158.6.1372  0.317
1988 Ding A, Nathan C. Analysis of the nonfunctional respiratory burst in murine Kupffer cells Journal of Experimental Medicine. 167: 1154-1170. PMID 3127523 DOI: 10.1084/Jem.167.3.1154  0.346
1988 Tsunawaki S, Sporn M, Ding A, Nathan C. Deactivation of macrophages by transforming growth factor-β Nature. 334: 260-262. PMID 3041283 DOI: 10.1038/334260A0  0.342
1987 Ding A, Wright SD, Nathan C. Activation of mouse peritoneal macrophages by monoclonal antibodies to Mac-1 (complement receptor type 3) Journal of Experimental Medicine. 165: 733-749. PMID 3102677 DOI: 10.1084/Jem.165.3.733  0.35
1987 O'Donnell-Tormey J, Nathan CF, Lanks K, DeBoer CJ, de la Harpe J. Secretion of pyruvate. An antioxidant defense of mammalian cells. The Journal of Experimental Medicine. 165: 500-14. PMID 3102672 DOI: 10.1084/Jem.165.2.500  0.342
1987 Nathan CF. Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes Journal of Clinical Investigation. 80: 1550-1560. PMID 2445780 DOI: 10.1172/Jci113241  0.319
1987 Fels AO, Nathan CF, Cohn ZA. Hydrogen peroxide release by alveolar macrophages from sarcoid patients and by alveolar macrophages from normals after exposure to recombinant interferons alpha A, beta, and gamma and 1,25-dihydroxyvitamin D3. The Journal of Clinical Investigation. 80: 381-6. PMID 2440910 DOI: 10.1172/Jci113083  0.544
1986 Gabay JE, Heiple JM, Cohn ZA, Nathan CF. Subcellular location and properties of bactericidal factors from human neutrophils. The Journal of Experimental Medicine. 164: 1407-21. PMID 3772295 DOI: 10.1084/Jem.164.5.1407  0.542
1986 Nathan CF. Macrophage activation: some questions Annales De L"Institut Pasteur. Immunologie. 137: 345-351. PMID 3090928 DOI: 10.1016/S0771-050X(86)80051-1  0.331
1986 Nathan CF, Tsunawaki S. Secretion of toxic oxygen products by macrophages: regulatory cytokines and their effects on the oxidase Ciba Foundation Symposium. 118: 211-230. PMID 3089712  0.311
1986 Nathan CF, Kaplan G, Levis WR, Nusrat A, Witmer MD, Sherwin SA, Job CK, Horowitz CR, Steinman RM, Cohn ZA. Local and systemic effects of intradermal recombinant interferon-gamma in patients with lepromatous leprosy. The New England Journal of Medicine. 315: 6-15. PMID 3086725 DOI: 10.1056/Nejm198607033150102  0.641
1986 Tsunawaki S, Nathan CF. Macrophage deactivation. Altered kinetic properties of superoxide-producing enzyme after exposure to tumor cell-conditioned medium Journal of Experimental Medicine. 164: 1319-1331. PMID 3020151 DOI: 10.1084/Jem.164.4.1319  0.376
1986 Montgomery RR, Nathan CF, Cohn ZA. Effects of reagent and cell-generated hydrogen peroxide on the properties of low density lipoprotein. Proceedings of the National Academy of Sciences of the United States of America. 83: 6631-5. PMID 3018740 DOI: 10.1073/Pnas.83.17.6631  0.554
1986 Young JD, Nathan CF, Podack ER, Palladino MA, Cohn ZA. Functional channel formation associated with cytotoxic T-cell granules. Proceedings of the National Academy of Sciences of the United States of America. 83: 150-4. PMID 2417234 DOI: 10.1073/Pnas.83.1.150  0.501
1985 Lepay DA, Steinman RM, Nathan CF, Murray HW, Cohn ZA. Liver macrophages in murine listeriosis. Cell-mediated immunity is correlated with an influx of macrophages capable of generating reactive oxygen intermediates. The Journal of Experimental Medicine. 161: 1503-12. PMID 4009118 DOI: 10.1084/Jem.161.6.1503  0.659
1985 De la Harpe J, Nathan CF. A semi-automated micro-assay for H2O2 release by human blood monocytes and mouse peritoneal macrophages Journal of Immunological Methods. 78: 323-336. PMID 3989315 DOI: 10.1016/0022-1759(85)90089-4  0.334
1985 Nathan CF, Horowitz CR, de La Harpe J, Vadhan-Raj S, Sherwin SA, Oettgen HF, Krown SE. Administration of recombinant interferon γ to cancer patients enhances monocyte secretion of hydrogen peroxide Proceedings of the National Academy of Sciences of the United States of America. 82: 8686-8690. PMID 3936042 DOI: 10.1073/Pnas.82.24.8686  0.348
1985 Arrick BA, Griffo W, Cohn Z, Nathan C. Hydrogen peroxide from cellular metabolism of cystine: A requirement for lysis of murine tumor cells by vernolepin, a glutathione-depleting antineoplastic Journal of Clinical Investigation. 76: 567-574. PMID 3928682 DOI: 10.1172/Jci112008  0.778
1985 Lepay DA, Nathan CF, Steinman RM, Murray HW, Cohn ZA. Murine Kupffer cells. Mononuclear phagocytes deficient in the generation of reactive oxygen intermediates. The Journal of Experimental Medicine. 161: 1079-96. PMID 3921651 DOI: 10.1084/Jem.161.5.1079  0.663
1985 O'Donnell-Tormey J, DeBoer CJ, Nathan CF. Resistance to human tumor cells in vitro to oxidative cytolysis Journal of Clinical Investigation. 76: 80-86. PMID 2991343 DOI: 10.1172/Jci111981  0.38
1985 Leijh PCJ, Nathan CF, Van den Barselaar MT, Van Furth R. Relationship between extracellular stimulation of intracellular killing and oxygen-dependent microbicidal systems of monocytes Infection and Immunity. 47: 502-507. PMID 2981774 DOI: 10.1128/Iai.47.2.502-507.1985  0.341
1984 Freedman VH, Gorrell TE, Nathan CF, Copeland CS, Silverstein SC. Bacillus Calmette-Guérin-activated murine macrophages kill syngeneic melanoma cells under strict anaerobic conditions. The Journal of Experimental Medicine. 160: 94-107. PMID 6736873 DOI: 10.1084/Jem.160.1.94  0.389
1984 Arrick BA, Nathan CF. Glutathione Metabolism as a Determinant of Therapeutic Efficacy: A Review Cancer Research. 44: 4224-4232. PMID 6380705  0.712
1984 Nathan CF, Prendergast TJ, Wiebe ME, Stanley ER, Platzer E, Remold HG, Welte K, Rubin BY, Murray HW. Activation of human macrophages. Comparison of other cytokines with interferon-γ Journal of Experimental Medicine. 160: 600-605. PMID 6206183 DOI: 10.1084/Jem.160.2.600  0.363
1983 Akira Nakagawara, Nathan CF. A simple method for counting adherent cells: Application to cultured human monocytes, Macrophages and multinucleated giant cells Journal of Immunological Methods. 56: 261-268. PMID 6827097 DOI: 10.1016/0022-1759(83)90418-0  0.309
1983 Nathan CF, Murray HW, Wiebe ME, Rubin BY. Identification of interferon-γ as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity Journal of Experimental Medicine. 158: 670-689. PMID 6411853 DOI: 10.1084/Jem.158.3.670  0.384
1983 Arrick BA, Nathan CF, Cohn ZA. Inhibition of glutathione synthesis augments lysis of murine tumor cells by sulfhydryl-reactive antineoplastics. The Journal of Clinical Investigation. 71: 258-67. PMID 6401768 DOI: 10.1172/Jci110766  0.773
1983 Nathan CF. Mechanisms of macrophage antimicrobial activity Transactions of the Royal Society of Tropical Medicine and Hygiene. 77: 620-630. PMID 6362115 DOI: 10.1016/0035-9203(83)90190-6  0.344
1983 Adams DO, Nathan CF. Molecular mechanisms in tumor-cell killing by activated macrophages Immunology Today. 4: 166-170. DOI: 10.1016/0167-5699(83)90005-1  0.337
1982 Szuro-Sudol A, Nathan CF. Suppression of macrophage oxidative metabolism by products of malignant and nonmalignant cells Journal of Experimental Medicine. 156: 945-961. PMID 7153714 DOI: 10.1084/Jem.156.4.945  0.394
1982 Nakagawara A, DeSantis NM, Nogueira N, Nathan CF. Lymphokines enhance the capacity of human monocytes to secrete reactive oxygen intermediates Journal of Clinical Investigation. 70: 1042-1048. PMID 7130393 DOI: 10.1172/Jci110691  0.343
1982 Nathan CF, Klebanoff SJ. Augmentation of spontaneous macrophage-mediated cytolysis by eosinophil peroxidase Journal of Experimental Medicine. 155: 1291-1308. PMID 6802924 DOI: 10.1084/Jem.155.5.1291  0.353
1982 Arrick BA, Nathan CF, Griffith OW, Cohn ZA. Glutathione depletion sensitizes tumor cells to oxidative cytolysis Journal of Biological Chemistry. 257: 1231-1237. PMID 6799503  0.741
1981 Nathan CF, Cohn ZA. Antitumor effects of hydrogen peroxide in vivo Journal of Experimental Medicine. 154: 1539-1553. PMID 7299347 DOI: 10.1084/Jem.154.5.1539  0.527
1981 Nathan CF, Arrick BA, Murray HW, DeSantis NM, Cohn ZA. Tumor cell anti-oxidant defenses. Inhibition of the glutathione redox cycle enhances macrophage-mediated cytolysis Journal of Experimental Medicine. 153: 766-782. PMID 7252413 DOI: 10.1084/Jem.153.4.766  0.776
1981 Nakagawara A, Nathan CF, Cohn ZA. Hydrogen peroxide metabolism in human monocytes during differentiation in vitro Journal of Clinical Investigation. 68: 1243-1252. PMID 6271809 DOI: 10.1172/Jci110370  0.559
1980 Murray HW, Nathan CF, Cohn ZA. Macrophage oxygen-dependent antimicrobial activity. IV. Role of endogenous scavengers of oxygen intermediates Journal of Experimental Medicine. 152: 1610-1624. PMID 7452149 DOI: 10.1084/Jem.152.6.1610  0.606
1980 Nathan C, Cohn Z. Role of oxygen-dependent mechanism in antibody-induced lysis of tumor cells by activated macrophages Journal of Experimental Medicine. 152: 198-208. PMID 6995553 DOI: 10.1084/Jem.152.1.198  0.571
1980 Nathan C, Brukner L, Kaplan G, Unkeless J, Cohn Z. Role of activated macrophages in antibody-dependent lysis of tumor cells. The Journal of Experimental Medicine. 152: 183-97. PMID 6995552 DOI: 10.1084/Jem.152.1.183  0.565
1980 Nathan CF, Murray HW, Cohn ZA. The macrophage as an effector cell New England Journal of Medicine. 303: 622-626. PMID 6447249 DOI: 10.1056/Nejm198009113031106  0.539
1979 Murray HW, Juangbhanich CW, Nathan CF, Cohn ZA. Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates Journal of Experimental Medicine. 150: 950-964. PMID 512587 DOI: 10.1084/Jem.150.4.950  0.603
1979 Nathan C, Nogueira N, Juangbhanich C, Ellis J, Cohn Z. Activation of macrophages in vivo and in vitro. Correlation between hydrogen peroxide release and killing of Trypanosoma cruzi. Journal of Experimental Medicine. 149: 1056-1068. PMID 376774 DOI: 10.1084/Jem.149.5.1056  0.596
1979 Nathan CF, Brukner LH, Silverstein SC, Cohn ZA. Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide Journal of Experimental Medicine. 149: 84-99. PMID 368287 DOI: 10.1084/Jem.149.1.84  0.578
1979 Nathan CF, Silverstein SC, Brukner LH, Cohn ZA. Extracellular cytolysis by activated macrophages and granulocytes. II. Hydrogen Peroxide as a mediator of cytotoxicity Journal of Experimental Medicine. 149: 100-113. PMID 216763 DOI: 10.1084/Jem.149.1.100  0.602
1977 Nathan CF, Root RK. Hydrogen peroxide release from mouse peritoneal macrophages. Dependence on sequential activation and triggering Journal of Experimental Medicine. 146: 1648-1662. PMID 925614 DOI: 10.1084/Jem.146.6.1648  0.374
1977 Nathan CF, Terry WD. Decreased phagocytosis by peritoneal macrophages from BCG-treated mice. Induction of the phagocytic defect in normal macrophages with BCG in vitro Cellular Immunology. 29: 295-311. PMID 324633 DOI: 10.1016/0008-8749(77)90324-0  0.379
1976 Nathan CF, Hill VM, Terry WD. Isolation of a subpopulation of adherent peritoneal cells with anti-tumour activity Nature. 260: 146-148. PMID 768773 DOI: 10.1038/260146A0  0.335
1975 Nathan CF, Terry WD. Differential stimulation of murine lymphoma growth in vitro by normal and BCG activated macrophages Journal of Experimental Medicine. 142: 887-902. PMID 170358 DOI: 10.1084/Jem.142.4.887  0.389
1973 Nathan CF, Remold HG, David JR. Characterization of a lymphocyte factor which alters macrophage functions Journal of Experimental Medicine. 137: 275-290. PMID 4119587 DOI: 10.1084/Jem.137.2.275  0.355
1971 Nathan CF, Karnovsky ML, David JR. Alterations of macrophage functions by mediators from lymphocytes Journal of Experimental Medicine. 133: 1356-1376. PMID 5576335 DOI: 10.1084/Jem.133.6.1356  0.352
Low-probability matches (unlikely to be authored by this person)
2001 Nathan C, Muller WA. Putting the brakes on innate immunity: A regulatory role for CD200? Nature Immunology. 2: 17-19. PMID 11135572 DOI: 10.1038/83124  0.299
1991 Raetz CRH, Ulevitch RT, Wright SD, Sibley CH, Ding A, Nathan CF. Gram-negative endotoxin: An extraordinary lipid with profound effects on eukaryotic signal transduction Faseb Journal. 5: 2652-2660. PMID 1916089 DOI: 10.1096/Fasebj.5.12.1916089  0.298
1982 Nathan CF. Secretion of oxygen intermediates: Role in effector functions of activated macrophages Federation Proceedings. 41: 2206-2211. PMID 6281078  0.298
2021 Gold B, Warrier T, Nathan C. A Multistress Model for High Throughput Screening Against Nonreplicating Mycobacterium tuberculosis. Methods in Molecular Biology (Clifton, N.J.). 2314: 611-635. PMID 34235673 DOI: 10.1007/978-1-0716-1460-0_27  0.298
1989 Nathan CF. Respiratory burst in adherent human neutrophils: Triggering by colony-stimulating factors CSF-GM and CSF-G Blood. 73: 301-306. PMID 2462939 DOI: 10.1182/Blood.V73.1.301.Bloodjournal731301  0.297
1987 Nathan CF. Secretory products of macrophages. The Journal of Clinical Investigation. 79: 319-26. PMID 3543052 DOI: 10.1172/Jci112815  0.297
2011 Nathan C. Is iNOS beginning to smoke? Cell. 147: 257-8. PMID 22000003 DOI: 10.1016/J.Cell.2011.09.031  0.297
1995 Xie K, Huang S, Dong Z, Juang SH, Gutman M, Xie QW, Nathan C, Fidler IJ. Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells. The Journal of Experimental Medicine. 181: 1333-43. PMID 7535333 DOI: 10.1084/Jem.181.4.1333  0.297
2014 Fan H, Angelo NG, Warren JD, Nathan CF, Lin G. Oxathiazolones Selectively Inhibit the Human Immunoproteasome over the Constitutive Proteasome. Acs Medicinal Chemistry Letters. 5: 405-10. PMID 24900849 DOI: 10.1021/Ml400531D  0.296
2002 Nathan C. Points of control in inflammation. Nature. 420: 846-52. PMID 12490957 DOI: 10.1038/Nature01320  0.296
2002 Shen C, Nathan C. Nonredundant antioxidant defense by multiple two-cysteine peroxiredoxins in human prostate cancer cells. Molecular Medicine (Cambridge, Mass.). 8: 95-102. PMID 12080185 DOI: 10.1007/Bf03402079  0.295
2010 de Carvalho LP, Fischer SM, Marrero J, Nathan C, Ehrt S, Rhee KY. Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates. Chemistry & Biology. 17: 1122-31. PMID 21035735 DOI: 10.1016/J.Chembiol.2010.08.009  0.294
1993 Nathan C, Xie Q, Halbwachs-Mecarelli L, Jin WW. Albumin inhibits neutrophil spreading and hydrogen peroxide release by blocking the shedding of CD43 (sialophorin, leukosialin) Journal of Cell Biology. 122: 243-256. PMID 8391001 DOI: 10.1083/Jcb.122.1.243  0.294
1990 Campanelli D, Detmers PA, Nathan CF, Gabay JE. Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties. The Journal of Clinical Investigation. 85: 904-15. PMID 2312733 DOI: 10.1172/Jci114518  0.293
1993 Vodovotz Y, Bogdan C, Paik J, Xie QW, Nathan C. Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta. The Journal of Experimental Medicine. 178: 605-13. PMID 7688028 DOI: 10.1084/Jem.178.2.605  0.293
1999 Grobmyer SR, Armstrong RC, Nicholson SC, Gabay C, Arend WP, Potter SH, Melchior M, Fritz LC, Nathan CF. Peptidomimetic fluoromethylketone rescues mice from lethal endotoxic shock. Molecular Medicine. 5: 585-594. DOI: 10.1007/Bf03402071  0.292
2002 Nathan C. Inducible nitric oxide synthase in the tuberculous human lung. American Journal of Respiratory and Critical Care Medicine. 166: 130-1. PMID 12119220 DOI: 10.1164/Rccm.2205016  0.292
2007 Casenghi M, Cole ST, Nathan CF. New approaches to filling the gap in tuberculosis drug discovery. Plos Medicine. 4: e293. PMID 17988169 DOI: 10.1371/Journal.Pmed.0040293  0.291
1990 Nathan C, Sanchez E. Tumor necrosis factor and CD11/CD18 (β2) integrins act synergistically to lower cAMP in human neutrophils Journal of Cell Biology. 111: 2171-2181. PMID 1699953 DOI: 10.1083/Jcb.111.5.2171  0.291
2020 Walsh KF, McAulay K, Lee MH, Vilbrun SC, Mathurin L, Francois DJ, Zimmerman M, Kaya F, Zhang N, Saito K, Ocheretina O, Savic R, Dartois V, Johnson WD, Pape JW, ... Nathan C, et al. Early bactericidal activity trial of nitazoxanide for pulmonary tuberculosis. Antimicrobial Agents and Chemotherapy. PMID 32071052 DOI: 10.1128/Aac.01956-19  0.291
1991 Campanelli D, Melchior M, Fu Y, Nakata M, Shuman H, Nathan C, Gabay JE. Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils. The Journal of Experimental Medicine. 172: 1709-15. PMID 2258701 DOI: 10.1084/Jem.172.6.1709  0.29
1996 Xie QW, Leung M, Fuortes M, Sassa S, Nathan C. Complementation analysis of mutants of nitric oxide synthase reveals that the active site requires two hemes. Proceedings of the National Academy of Sciences of the United States of America. 93: 4891-6. PMID 8643499 DOI: 10.1073/Pnas.93.10.4891  0.29
1990 Ding AH, Porteu F, Sanchez E, Nathan CF. Shared actions of endotoxin and taxol on TNF receptors and TNF release. Science (New York, N.Y.). 248: 370-2. PMID 1970196 DOI: 10.1126/Science.1970196  0.289
2020 Drutman SB, Mansouri D, Mahdaviani SA, Neehus AL, Hum D, Bryk R, Hernandez N, Belkaya S, Rapaport F, Bigio B, Fisch R, Rahman M, Khan T, Al Ali F, Marjani M, ... ... Nathan C, et al. Fatal Cytomegalovirus Infection in an Adult with Inherited NOS2 Deficiency. The New England Journal of Medicine. 382: 437-445. PMID 31995689 DOI: 10.1056/Nejmoa1910640  0.288
1990 Ding AH, Porteu F, Sanchez E, Nathan CF. Downregulation of tumor necrosis factor receptors on macrophages and endothelial cells by microtubule depolymerizing agents. The Journal of Experimental Medicine. 171: 715-27. PMID 2155279 DOI: 10.1084/Jem.171.3.715  0.286
2006 Nathan C. Role of iNOS in human host defense. Science (New York, N.Y.). 312: 1874-5; author reply. PMID 16809512 DOI: 10.1126/Science.312.5782.1874B  0.284
1988 Yoshida R, Murray HW, Nathan CF. Agonist and antagonist effects of interferon alpha and beta on activation of human macrophages. Two classes of interferon gamma receptors and blockade of the high-affinity sites by interferon alpha or beta. The Journal of Experimental Medicine. 167: 1171-85. PMID 2965208 DOI: 10.1084/Jem.167.3.1171  0.283
1993 Fuortes M, Jin WW, Nathan C. Adhesion-dependent protein tyrosine phosphorylation in neutrophils treated with tumor necrosis factor Journal of Cell Biology. 120: 777-784. PMID 8425901 DOI: 10.1083/Jcb.120.3.777  0.282
2023 Lee AM, Laurent P, Nathan CF, Barrat FJ. Neutrophil-plasmacytoid dendritic cell interaction leads to production of type I IFN in response to Mycobacterium tuberculosis. European Journal of Immunology. e2350666. PMID 38161237 DOI: 10.1002/eji.202350666  0.281
1994 Nathan C. Nitric oxide and biopterin: A study in chiaroscuro Journal of Clinical Investigation. 93: 1875-1876. PMID 7514187 DOI: 10.1172/Jci117176  0.28
2014 Nathan C, Cars O. Antibiotic resistance--problems, progress, and prospects. The New England Journal of Medicine. 371: 1761-3. PMID 25271470 DOI: 10.1056/Nejmp1408040  0.28
2005 Nathan C, Calingasan N, Nezezon J, Ding A, Lucia MS, La Perle K, Fuortes M, Lin M, Ehrt S, Kwon NS, Chen J, Vodovotz Y, Kipiani K, Beal MF. Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase. The Journal of Experimental Medicine. 202: 1163-9. PMID 16260491 DOI: 10.1084/Jem.20051529  0.279
2010 Dumont M, Wille E, Calingasan NY, Nathan C, Flint Beal M, Lin MT. N-iminoethyl-L-lysine improves memory and reduces amyloid pathology in a transgenic mouse model of amyloid deposition. Neurochemistry International. 56: 345-51. PMID 19914323 DOI: 10.1016/J.Neuint.2009.11.006  0.279
1994 Fuortes M, Jin WW, Nathan C. β2 Integrin-dependent tyrosine phosphorylation of paxillin in human neutrophils treated with tumor necrosis factor Journal of Cell Biology. 127: 1477-1483. PMID 7525608 DOI: 10.1083/Jcb.127.5.1477  0.278
2015 Nathan C. What can immunology contribute to the control of the world's leading cause of death from bacterial infection? Immunological Reviews. 264: 2-5. PMID 25703548 DOI: 10.1111/Imr.12277  0.275
1988 Ding AH, Nathan CF. The measurement of cytochrome b559 in polymorphonuclear leukocytes and macrophages in the presence of hemoglobin or mitochondrial cytochromes Analytical Biochemistry. 175: 22-29. PMID 3245568 DOI: 10.1016/0003-2697(88)90355-7  0.275
1992 Porteu F, Nathan CF. Mobilizable intracellular pool of p55 (type I) tumor necrosis factor receptors in human neutrophils Journal of Leukocyte Biology. 52: 122-124. PMID 1322441 DOI: 10.1002/Jlb.52.1.122  0.273
2021 Pandey S, Singh A, Yang G, d'Andrea FB, Jiang X, Hartman TE, Mosior JW, Bourland R, Gold B, Roberts J, Geiger A, Tang S, Rhee K, Ouerfelli O, Sacchettini JC, ... Nathan CF, et al. Characterization of Phosphopantetheinyl Hydrolase from Mycobacterium tuberculosis. Microbiology Spectrum. e0092821. PMID 34550010 DOI: 10.1128/Spectrum.00928-21  0.273
2003 Nathan C. Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signaling. The Journal of Clinical Investigation. 111: 769-78. PMID 12639979 DOI: 10.1172/Jci18174  0.269
2010 Zhao H, de Carvalho LP, Nathan C, Ouerfelli O. A protecting group-free synthesis of deazathiamine: a step toward inhibitor design. Bioorganic & Medicinal Chemistry Letters. 20: 6472-4. PMID 20943392 DOI: 10.1016/J.Bmcl.2010.09.053  0.269
1993 Bogdan C, Nathan C. Modulation of macrophage function by transforming growth factor β, interleukin-4, and interleukin-10 Annals of the New York Academy of Sciences. 685: 713-739. PMID 8363277 DOI: 10.1111/J.1749-6632.1993.Tb35934.X  0.268
2021 Wipperman MF, Bhattarai SK, Vorkas CK, Maringati VS, Taur Y, Mathurin L, McAulay K, Vilbrun SC, Francois D, Bean J, Walsh KF, Nathan C, Fitzgerald DW, Glickman MS, Bucci V. Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis. Nature Communications. 12: 1141. PMID 33602926 DOI: 10.1038/s41467-021-21475-y  0.266
2018 Kirkman LA, Zhan W, Visone J, Dziedziech A, Singh PK, Fan H, Tong X, Bruzual I, Hara R, Kawasaki M, Imaeda T, Okamoto R, Sato K, Michino M, Alvaro EF, ... ... Nathan CF, et al. Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance. Proceedings of the National Academy of Sciences of the United States of America. PMID 29967165 DOI: 10.1073/Pnas.1806109115  0.263
2021 Ginn J, Jiang X, Sun S, Michino M, Huggins DJ, Mbambo Z, Jansen R, Rhee KY, Arango N, Lima CD, Liverton N, Imaeda T, Okamoto R, Kuroita T, Aso K, ... ... Nathan C, et al. Whole Cell Active Inhibitors of Mycobacterial Lipoamide Dehydrogenase Afford Selectivity over the Human Enzyme through Tight Binding Interactions. Acs Infectious Diseases. PMID 33527832 DOI: 10.1021/acsinfecdis.0c00788  0.263
2019 Quezada LL, Li K, McDonald SL, Nguyen Q, Perkowski AJ, Pharr CW, Gold B, Roberts J, McAulay K, Saito K, Karakaya SS, Javidnia PE, Porras de Francisco E, Amieva MM, Palomo S, ... ... Nathan C, et al. Correction to "Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating ". Acs Infectious Diseases. PMID 31670500 DOI: 10.1021/Acsinfecdis.9B00395  0.263
1986 Vadhan-Raj S, Al-Katib A, Bhalla R, Pelus L, Nathan CF, Sherwin SA, Oettgen HF, Krown SE. Phase I trial of recombinant interferon gamma in cancer patients Journal of Clinical Oncology. 4: 137-146. PMID 3080551 DOI: 10.1200/Jco.1986.4.2.137  0.263
1990 Nathan C, Squires K, Griffo W, Levis W, Varghese M, Job CK, Nusrat AR, Sherwin S, Rappoport S, Sanchez E. Widespread intradermal accumulation of mononuclear leukocytes in lepromatous leprosy patients treated systemically with recombinant interferon gamma. Journal of Experimental Medicine. 172: 1509-1512. PMID 2121891 DOI: 10.1084/Jem.172.5.1509  0.263
2020 Nathan C. Resisting antimicrobial resistance. Nature Reviews. Microbiology. 18: 259-260. PMID 32300248 DOI: 10.1038/S41579-020-0348-5  0.261
1991 Almeida RP, Melchior M, Campanelli D, Nathan C, Gabay JE. Complementary DNA sequence of human neutrophil azurocidin, an antibiotic with extensive homology to serine proteases Biochemical and Biophysical Research Communications. 177: 688-695. PMID 2049091 DOI: 10.1016/0006-291X(91)91843-2  0.26
2015 Nathan C. IMMUNOLOGY. From transient infection to chronic disease. Science (New York, N.Y.). 350: 161. PMID 26450196 DOI: 10.1126/Science.Aad4141  0.258
1996 Ruan J, Xie Qw, Hutchinson N, Cho H, Wolfe GC, Nathan C. Inducible nitric oxide synthase requires both the canonical calmodulin-binding domain and additional sequences in order to bind calmodulin and produce nitric oxide in the absence of free Ca2+. The Journal of Biological Chemistry. 271: 22679-86. PMID 8798440 DOI: 10.1074/Jbc.271.37.22679  0.258
1998 Nicholson SC, Grobmyer SR, Brause JE, Dinauer MC, Nathan CF. DEFICIENCY OF PHAGOCYTE OXIDASE CONFERS NO SURVIVAL BENEFIT IN A MOUSE MODEL OF SEPTIC SHOCK. Shock. 9: 24. DOI: 10.1097/00024382-199806001-00080  0.253
2008 Nathan C. Epidemic inflammation: pondering obesity. Molecular Medicine (Cambridge, Mass.). 14: 485-92. PMID 18431463 DOI: 10.2119/2008-00038.Nathan  0.252
1984 Tsunawaki S, Nathan CF. Enzymatic basis of macrophage activation. Kinetic analysis of superoxide production in lysates of resident and activated mouse peritoneal macrophages and granulocytes Journal of Biological Chemistry. 259: 4305-4312. PMID 6323464  0.251
2010 Nathan C, Ding A. SnapShot: Reactive Oxygen Intermediates (ROI). Cell. 140: 951-951.e2. PMID 20303882 DOI: 10.1016/J.Cell.2010.03.008  0.25
1996 Vodovotz Y, Lucia MS, Flanders KC, Chesler L, Xie QW, Smith TW, Weidner J, Mumford R, Webber R, Nathan C, Roberts AB, Lippa CF, Sporn MB. Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease. The Journal of Experimental Medicine. 184: 1425-33. PMID 8879214 DOI: 10.1084/Jem.184.4.1425  0.249
2013 Russell DG, Nathan CF. Perspective: Graduation time. Nature. 502: S7. PMID 24108080 DOI: 10.1038/502S7A  0.249
2008 Nathan C. Metchnikoff's Legacy in 2008. Nature Immunology. 9: 695-8. PMID 18563074 DOI: 10.1038/Ni0708-695  0.248
2010 Yin F, Dumont M, Banerjee R, Ma Y, Li H, Lin MT, Beal MF, Nathan C, Thomas B, Ding A. Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 4639-47. PMID 20667979 DOI: 10.1096/fj.10.161471  0.248
1988 McGrogan M, Simonsen C, Scott R, Griffith J, Ellis N, Kennedy J, Campanelli D, Nathan C, Gabay J. Isolation Of A Complementary Dna Clone Encoding A Precursor To Human Eosinophil Major Basic Protein Journal of Experimental Medicine. 168: 2295-2308. PMID 3199069 DOI: 10.1084/Jem.168.6.2295  0.248
2011 Nathan C. Making space for anti-infective drug discovery. Cell Host & Microbe. 9: 343-8. PMID 21575903 DOI: 10.1016/J.Chom.2011.04.013  0.245
1991 Nathan C, Sporn M. Cytokines in context Journal of Cell Biology. 113: 981-986. PMID 2040651 DOI: 10.1083/Jcb.113.5.981  0.244
1986 Nathan CF. Peroxide and pteridine: a hypothesis on the regulation of macrophage antimicrobial activity by interferon gamma Interferon. 7: 125-143. PMID 3102389  0.243
1994 Minasian L, Szatrowski T, Rosenblum M, Steffens T, Morrison M, Chapman P, Williams L, Nathan C, Houghton A. Hemorrhagic tumor necrosis during a pilot trial of tumor necrosis factor-alpha and anti-GD3 ganglioside monoclonal antibody in patients with metastatic melanoma Blood. 83: 56-64. DOI: 10.1182/Blood.V83.1.56.56  0.243
2011 So AD, Gupta N, Brahmachari SK, Chopra I, Munos B, Nathan C, Outterson K, Paccaud JP, Payne DJ, Peeling RW, Spigelman M, Weigelt J. Towards new business models for R&D for novel antibiotics Drug Resistance Updates. 14: 88-94. PMID 21439891 DOI: 10.1016/J.Drup.2011.01.006  0.241
2021 Ah Kioon MD, Pierides M, Pannellini T, Lin G, Nathan CF, Barrat FJ. Noncytotoxic Inhibition of the Immunoproteasome Regulates Human Immune Cells In Vitro and Suppresses Cutaneous Inflammation in the Mouse. Journal of Immunology (Baltimore, Md. : 1950). PMID 33674446 DOI: 10.4049/jimmunol.2000951  0.24
2007 Fang FC, Nathan CF. Man is not a mouse: reply. Journal of Leukocyte Biology. 81: 580. PMID 17332374 DOI: 10.1189/Jlb.1206715  0.24
2015 Nathan C. Cooperative development of antimicrobials: looking back to look ahead. Nature Reviews. Microbiology. 13: 651-7. PMID 26373373 DOI: 10.1038/Nrmicro3523  0.239
1992 Roberts AB, Vodovotz Y, Roche NS, Sporn MB, Nathan CF. Role of nitric oxide in antagonistic effects of transforming growth factor-beta and interleukin-1 beta on the beating rate of cultured cardiac myocytes. Molecular Endocrinology (Baltimore, Md.). 6: 1921-30. PMID 1282674 DOI: 10.1210/Mend.6.11.1282674  0.237
2000 Grobmyer SR, Lin E, Lowry SF, Rivadeneira DE, Potter S, Barie PS, Nathan CF. Elevation of IL-18 in human sepsis. Journal of Clinical Immunology. 20: 212-5. PMID 10941829 DOI: 10.1023/A:1006641630904  0.234
2018 Yu H, Lupoli TJ, Kovach A, Meng X, Zhao G, Nathan CF, Li H. ATP hydrolysis-coupled peptide translocation mechanism of ClpB. Proceedings of the National Academy of Sciences of the United States of America. PMID 30257943 DOI: 10.1073/Pnas.1810648115  0.231
1993 Kleemann R, Rothe H, Kolb-Bachofen V, Xie Q, Nathan C, Martin S, Kolb H. Transcription and translation of inducible nitric oxide synthase in the pancreas of prediabetic BB rats Febs Letters. 328: 9-12. PMID 7688327 DOI: 10.1016/0014-5793(93)80954-S  0.231
2020 Harnagel A, Lopez Quezada L, Park SW, Baranowski C, Kieser K, Jiang X, Roberts J, Vaubourgeix J, Yang A, Nelson B, Fay A, Rubin E, Ehrt S, Nathan C, Lupoli TJ. Non-redundant functions of Mycobacterium tuberculosis chaperones promote survival under stress. Molecular Microbiology. PMID 32996193 DOI: 10.1111/mmi.14615  0.229
2012 Osterloh JM, Yang J, Rooney TM, Fox AN, Adalbert R, Powell EH, Sheehan AE, Avery MA, Hackett R, Logan MA, MacDonald JM, Ziegenfuss JS, Milde S, Hou YJ, Nathan C, et al. dSarm/Sarm1 is required for activation of an injury-induced axon death pathway. Science (New York, N.Y.). 337: 481-4. PMID 22678360 DOI: 10.1126/Science.1223899  0.229
2007 Bass AR, Schneider R, Sanders A, Flieder D, Nathan CF, Erkan D. Pulmonary nodules in an infliximab-treated rheumatoid arthritis patient: a clinical pathology conference held by the Division of Rheumatology at Hospital for Special Surgery. Hss Journal : the Musculoskeletal Journal of Hospital For Special Surgery. 3: 119-25. PMID 18751782 DOI: 10.1007/S11420-006-9032-1  0.228
2020 Nathan C. Neutrophils and COVID-19: Nots, NETs, and knots. The Journal of Experimental Medicine. 217. PMID 32678431 DOI: 10.1084/Jem.20201439  0.228
2022 Zainabadi K, Saito K, Mishra S, Walsh KF, Mathurin LD, Vilbrun SC, Ocheretina O, Pape JW, Fitzgerald DW, Nathan CF, Lee MH. Transcriptional Biomarkers of Differentially Detectable Mycobacterium tuberculosis in Patient Sputum. Mbio. e0270122. PMID 36326252 DOI: 10.1128/mbio.02701-22  0.225
1989 Nathan C, Srimal S, Farber C, Sanchez E, Kabbash L, Asch A, Gailit J, Wright SD. Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins. Journal of Cell Biology. 109: 1341-1349. PMID 2475511 DOI: 10.1083/Jcb.109.3.1341  0.225
1987 Ding AH, Nathan CF. Trace levels of bacterial lipopolysaccharide prevent interferon-γ or tumor necrosis factor-α from enhancing mouse peritoneal macrophage respiratory burst capacity Journal of Immunology. 139: 1971-1977. PMID 3040860  0.223
2004 Nathan C. Antibiotics at the crossroads. Nature. 431: 899-902. PMID 15496893 DOI: 10.1038/431899A  0.222
2013 Nathan C. A journey in science: promise, purpose, privilege. Molecular Medicine (Cambridge, Mass.). 19: 305-13. PMID 24089245 DOI: 10.2119/Molmed.2013.00063  0.216
2019 Zimmerman M, McDonald SL, Ho-Liang HP, Porubsky P, Nguyen Q, Pharr CW, Perkowski AJ, Smith R, Schoenen FJ, Gold BS, Zhang D, Nathan CF, Dartois V, Aubé J. Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma. The Journal of Antibiotics. PMID 30903100 DOI: 10.1038/S41429-019-0167-Y  0.216
2020 Zhan W, Singh PK, Ban Y, Qing X, Ah Kioon MD, Fan H, Zhao Q, Wang R, Sukenick G, Salmon J, Warren JD, Ma X, Barrat FJ, Nathan CF, Lin G. Structure-Activity Relationships of Noncovalent Immunoproteasome β5i-Selective Dipeptides. Journal of Medicinal Chemistry. PMID 33095579 DOI: 10.1021/acs.jmedchem.0c01520  0.211
1991 Szatrowski TP, Nathan CF. Production of Large Amounts of Hydrogen Peroxide by Human Tumor Cells Cancer Research. 51: 794-798. PMID 1846317  0.21
2016 Casanova JL, Nathan CF, Nussenzweig MC. Human studies at JEM: Immunology and beyond. The Journal of Experimental Medicine. PMID 26976629 DOI: 10.1084/Jem.20160211  0.208
2022 Gold B, Zhang J, Quezada LL, Roberts J, Ling Y, Wood M, Shinwari W, Goullieux L, Roubert C, Fraisse L, Bacqué E, Lagrange S, Filoche-Rommé B, Vieth M, Hipskind PA, ... ... Nathan C, et al. Identification of β-Lactams Active against by a Consortium of Pharmaceutical Companies and Academic Institutions. Acs Infectious Diseases. PMID 35192346 DOI: 10.1021/acsinfecdis.1c00570  0.207
2007 Nathan C. Aligning pharmaceutical innovation with medical need. Nature Medicine. 13: 304-8. PMID 17342145 DOI: 10.1038/Nm0307-304  0.204
2005 Nathan C, Goldberg FM. Outlook: the profit problem in antibiotic R&D. Nature Reviews. Drug Discovery. 4: 887-91. PMID 16247440 DOI: 10.1038/Nrd1878  0.204
2021 Schrader SM, Botella H, Jansen R, Ehrt S, Rhee K, Nathan C, Vaubourgeix J. Multiform antimicrobial resistance from a metabolic mutation. Science Advances. 7. PMID 34452915 DOI: 10.1126/sciadv.abh2037  0.202
2023 Zhan W, Li D, Subramanyaswamy SB, Liu YJ, Yang C, Zhang H, Harris JC, Wang R, Zhu S, Rocha H, Sherman J, Qin J, Herring M, Simwela NV, Waters AP, ... ... Nathan CF, et al. Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance. Cell Chemical Biology. PMID 37148884 DOI: 10.1016/j.chembiol.2023.04.006  0.201
2009 Dumont M, Wille E, Calingasan NY, Tampellini D, Williams C, Gouras GK, Liby K, Sporn M, Nathan C, Beal MF, Lin MT. Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease: (Journal of Neurochemistry (2009) 109 (502-512)) Journal of Neurochemistry. 109: 1192. DOI: 10.1111/J.1471-4159.2009.06053.X  0.2
1986 Tsunawaki S, Nathan CF. Release of arachidonate and reduction of oxygen. Independent metabolic bursts of the mouse peritoneal macrophage Journal of Biological Chemistry. 261: 11563-11570. PMID 3091592  0.2
2021 Zainabadi K, Walsh KF, Vilbrun SC, Mathurin LD, Lee MH, Saito K, Mishra S, Ocheretina O, Pape JW, Nathan C, Fitzgerald DW. Characterization of differentially detectable in the sputum of subjects with drug sensitive or drug resistant tuberculosis before and after two months of therapy. Antimicrobial Agents and Chemotherapy. AAC0060821. PMID 34060896 DOI: 10.1128/AAC.00608-21  0.195
2015 Nathan C, Stadanlick J. Video podcast: Tuberculosis. Immunological Reviews. 264: 1. PMID 25703547 DOI: 10.1111/imr.12262  0.195
2020 Nathan CF, Nussenzweig MC, Pulvirenti T. JEM goes viral. The Journal of Experimental Medicine. 217. PMID 31961374 DOI: 10.1084/Jem.20200046  0.194
1989 Grant IH, Gold JWM, Wittner M, Tanowitz HB, Nathan C, Mayer K, Reich L, Wollner N, Steinherz L, Ghavimi F, O'Reilly RJ, Armstrong D. Transfusion-Associated Acute Chagas Disease Acquired in the United States Annals of Internal Medicine. 111: 849-851. PMID 2510571 DOI: 10.7326/0003-4819-111-10-849  0.191
2023 Ottavi S, Li K, Cacioppo JG, Perkowski AJ, Ramesh R, Gold BS, Ling Y, Roberts J, Singh A, Zhang D, Mosior J, Goullieux L, Roubert C, Bacqué E, Sacchettini JC, ... Nathan CF, et al. PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas. Acs Medicinal Chemistry Letters. 14: 970-976. PMID 37465309 DOI: 10.1021/acsmedchemlett.3c00162  0.191
1993 Xie QW, Nathan C. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon-gamma and bacterial lipopolysaccharide Transactions of the Association of American Physicians. 106: 1-12. PMID 7518621  0.188
2017 Nathan C, Nussenzweig MC, Pulvirenti T. JEM Advisory Editorial Board: Increasing diversity. The Journal of Experimental Medicine. 214: 2169. PMID 31986531 DOI: 10.1084/Jem.20171220  0.188
2023 Zhang H, Ginn J, Zhan W, Leung A, Liu YJ, Toita A, Okamoto R, Wong TT, Imaeda T, Hara R, Michino M, Yukawa T, Chelebieva S, Tumwebaze PK, Vendome J, ... ... Nathan CF, et al. Structure-Activity Relationship Studies of Antimalarial Proteasome Inhibitors─Part II. Journal of Medicinal Chemistry. PMID 36630286 DOI: 10.1021/acs.jmedchem.2c01651  0.187
1991 Nathan C. Mechanisms and modulation of macrophage activation Behring Institut Mitteilungen. 200-207. PMID 2049039  0.185
2017 Nathan CF. Introduction of Laurie H. Glimcher, MD. The Journal of Clinical Investigation. 127: 3575. PMID 28968255 DOI: 10.1172/Jci97404  0.181
2017 Nathan CF, Nussenzweig MC, Pulvirenti T. A time of change. The Journal of Experimental Medicine. 214: 1-2. PMID 31993625 DOI: 10.1084/Jem.20162116  0.181
2022 Ottavi S, Scarry SM, Mosior J, Ling Y, Roberts J, Singh A, Zhang D, Goullieux L, Roubert C, Bacqué E, Lagiakos HR, Vendome J, Moraca F, Li K, Perkowski AJ, ... ... Nathan CF, et al. In Vitro and In Vivo Inhibition of the Phosphopantetheinyl Transferase PptT by Amidinoureas. Journal of Medicinal Chemistry. PMID 35044775 DOI: 10.1021/acs.jmedchem.1c01565  0.181
2017 Nathan C, Nussenzweig M, Pulvirenti T. The new face of JEM. The Journal of Experimental Medicine. 214: 3467. PMID 29187610 DOI: 10.1084/Jem.20172072  0.181
1978 Kabins SA, Nathan C. In vitro activity of 5-episisomicin in bacteria resistant to other aminoglycoside antibiotics Antimicrobial Agents and Chemotherapy. 14: 391-397. PMID 101131  0.178
1994 Xie QW, Kashiwabara Y, Nathan C. Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase Journal of Biological Chemistry. 269: 4705-4708. PMID 7508926  0.178
1991 Nathan C. Workshop summary: Negative regulation of macrophage effector function Annals of the New York Academy of Sciences. 628: 410. PMID 2069317  0.178
2011 Nathan C. Ralph Steinman 1943–2011 Nature Immunology. 12: 1129-1129. DOI: 10.1038/Ni.2160  0.177
2024 Singh A, Ottavi S, Krieger I, Planck K, Perkowski A, Kaneko T, Davis AM, Suh C, Zhang D, Goullieux L, Alex A, Roubert C, Gardner M, Preston M, Smith DM, ... ... Nathan C, et al. Redirecting raltitrexed from cancer cell thymidylate synthase to phosphopantetheinyl transferase. Science Advances. 10: eadj6406. PMID 38489355 DOI: 10.1126/sciadv.adj6406  0.176
2021 Lin G, Zhan W, Zhang H, Ginn J, Leung A, Liu YJ, Michino M, Toita A, Wong TT, Imaeda T, Hara R, Yukawa T, Chelebieva S, Tumwebaze PK, Lafuente-Monasterio MJ, ... ... Nathan CF, et al. Development of a highly selective Plasmodium falciparum proteasome inhibitor with anti-malaria activity in humanized mice. Angewandte Chemie (International Ed. in English). PMID 33433953 DOI: 10.1002/anie.202015845  0.173
2010 Nathan C, Ding A. Nonresolving inflammation. Cell. 140: 871-82. PMID 20303877 DOI: 10.1016/j.cell.2010.02.029  0.167
2019 Nathan CF, Nussenzweig MC, Pulvirenti T. Editorial Board: Expanding on the basis of cancer. The Journal of Experimental Medicine. PMID 31262843 DOI: 10.1084/Jem.20191171  0.166
1991 Bogdan C, Vodovotz Y, Nathan C. Macrophage deactivation by interleukin 10. The Journal of Experimental Medicine. 174: 1549-55. PMID 1744584 DOI: 10.1084/Jem.174.6.1549  0.163
2023 Nathan C. Mycobacterium tuberculosis as teacher. Nature Microbiology. PMID 37587200 DOI: 10.1038/s41564-023-01454-3  0.163
2022 Zhang H, Ginn J, Zhan W, Liu YJ, Leung A, Toita A, Okamoto R, Wong TT, Imaeda T, Hara R, Yukawa T, Michino M, Vendome J, Beuming T, Sato K, ... ... Nathan CF, et al. Design, Synthesis, and Optimization of Macrocyclic Peptides as Species-Selective Antimalaria Proteasome Inhibitors. Journal of Medicinal Chemistry. PMID 35727231 DOI: 10.1021/acs.jmedchem.2c00611  0.156
2020 Nathan CF, Nussenzweig MC, Pulvirenti T. We are here for you and ready to hear from you. The Journal of Experimental Medicine. 217. PMID 32232431 DOI: 10.1084/Jem.20200567  0.155
1994 Nathan C, Xie QW. Regulation of biosynthesis of nitric oxide Journal of Biological Chemistry. 269: 13725-13728. PMID 7514592  0.153
1992 Ding A, Sanchez E, Tancinco M, Nathan C. Interactions of bacterial lipopolysaccharide with microtubule proteins Journal of Immunology. 148: 2853-2858. PMID 1573273  0.151
1976 Kabins SA, Nathan C, Cohen S. In vitro comparison of netilmicin, a semisynthetic derivative of sisomicin, and four other aminoglycoside antibiotics Antimicrobial Agents and Chemotherapy. 10: 139-145. PMID 825021  0.147
1983 Olson B, Weinstein RA, Nathan C, Kabins SA. Broad-spectrum β-lactam resistance in enterobacter: Emergence during treatment and mechanisms of resistance Journal of Antimicrobial Chemotherapy. 11: 299-310. PMID 6602122 DOI: 10.1093/jac/11.4.299  0.145
2021 Saito K, Mishra S, Warrier T, Cicchetti N, Mi J, Weber E, Jiang X, Roberts J, Gouzy A, Kaplan E, Brown CD, Gold B, Nathan C. Oxidative damage and delayed replication allow viable to go undetected. Science Translational Medicine. 13: eabg2612. PMID 34818059 DOI: 10.1126/scitranslmed.abg2612  0.14
1980 Weinstein RA, Nathan C, Gruensfelder R, Kabins SA. Endemic aminoglycoside resistance in gram-negative bacilli: Epidemiology and mechanisms Journal of Infectious Diseases. 141: 338-345. PMID 6767795  0.14
1989 Tsunawaki S, Sporn M, Nathan C. Comparison of transforming growth factor-β and a macrophage-deactivating polypeptide from tumor cells. Differences in antigenicity and mechanism of action Journal of Immunology. 142: 3462-3468. PMID 2715632  0.14
2022 Nathan C. Nonresolving inflammation redux. Immunity. 55: 592-605. PMID 35417674 DOI: 10.1016/j.immuni.2022.03.016  0.133
1974 Kabins S, Nathan C, Cohen S. Gentamicin-adenylyltransferase activity as a cause of gentamicin resistance in clinical isolates of Pseudomonas aeruginosa Antimicrobial Agents and Chemotherapy. 5: 565-570. PMID 15825406  0.131
1982 Weinstein RA, Nathan C, Kabins SA. Comparative in-vitro activity of sch 29482 and six other extended spectrum cephalosporins Journal of Antimicrobial Chemotherapy. 9: 41-48. PMID 7061376 DOI: 10.1093/jac/9.suppl_C.41  0.129
2021 Calderón F, Fairlamb AH, Strange M, Williams P, Nathan CF. Surmounting structural barriers to tackle endemic infectious diseases. The Journal of Experimental Medicine. 218. PMID 34410327 DOI: 10.1084/jem.20211418  0.128
2009 Dumont M, Wille E, Calingasan NY, Tampellini D, Williams C, Gouras GK, Liby K, Sporn M, Nathan C, Flint Beal M, Lin MT. Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease. Journal of Neurochemistry. 109: 502-12. PMID 19200343 DOI: 10.1111/J.1471-4159.2009.05970.X  0.126
2021 Aldridge BB, Barros-Aguirre D, Barry CE, Bates RH, Berthel SJ, Boshoff HI, Chibale K, Chu XJ, Cooper CB, Dartois V, Duncan K, Fotouhi N, Gusovsky F, Hipskind PA, Kempf DJ, ... ... Nathan C, et al. The Tuberculosis Drug Accelerator at year 10: what have we learned? Nature Medicine. PMID 34226736 DOI: 10.1038/s41591-021-01442-2  0.125
1990 Flaherty J, Nathan C, Kabins SA, Weinstein RA. Pilot trial of selective decontamination for prevention of bacterial infection in an intensive care unit Journal of Infectious Diseases. 162: 1393-1397. PMID 2230272 DOI: 10.1093/infdis/162.6.1393  0.122
1987 Weinstein RA, Nathan C, Delzell D, Kabins SA. In vitro susceptibility of nosocomial Pseudomonas aeruginosa, enterobacteriaceae, and staphylococci to ciprofloxacin and ten other broad-spectrum antibiotics Chemioterapia. 6: 315-318. PMID 3123078  0.114
1967 Kasnitz P, Grant L, Napoliello M, Nathan C. The use of Alcian Blue in vivo - I. Physiologic considerations Histochemie. 10: 107-114. PMID 4171992 DOI: 10.1007/BF00311401  0.106
1987 Nathan C, Rolland Y. Pharmacological treatments that affect CNS activity: Serotonin Annals of the New York Academy of Sciences. 499: 277-296. PMID 3300487  0.102
1978 Kabins SA, Nathan C. In vitro activity of Sch 21420, derivative of gentamicin B, compared to that of amikacin Antimicrobial Agents and Chemotherapy. 14: 786-787. PMID 727766  0.095
1992 Bogdan C, Paik J, Vodovotz Y, Nathan C. Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-β and interleukin-10 Journal of Biological Chemistry. 267: 23301-23308. PMID 1429677  0.093
1997 Bonten MJM, Nathan C, Weinstein RA. Recovery of nosocomial fecal flora from frozen stool specimens and rectal swabs: Comparison of preservatives for epidemiological studies Diagnostic Microbiology and Infectious Disease. 27: 103-106. PMID 9154404 DOI: 10.1016/S0732-8893(97)00024-2  0.088
1974 Schaison G, Nathan C, Gilbert Dreyfus. Three cases of thyroid medullary carcinoma: biologic study Annales D'Endocrinologie. 35: 291-293. PMID 4377071  0.085
1974 Nathan CF. Cryptococcal osteomyelitis treated with 5 fluorocytosine Amer.Rev.Resp.Dis.. 110: 78-81. PMID 4599881  0.083
2021 Nathan C. Rethinking immunology. Science (New York, N.Y.). 373: 276-277. PMID 34437138 DOI: 10.1126/science.abj5637  0.078
1973 Schaison G, Nathan C, Gilbert Dreyfus. A female case of Prader and Willi syndrome; exploration at the post puberal age Annales D'Endocrinologie. 34: 286-288. PMID 4751204  0.069
1991 Campbell DB, Lavielle R, Nathan C. The mode of action and clinical pharmacology of gliclazide: a review Diabetes Research and Clinical Practice. 14. PMID 1794262 DOI: 10.1016/0168-8227(91)90005-X  0.067
1989 Sasson S, Kunievsky B, Nathan C, Cerasi E. Failure of fenfluramine to affect basal and insulin-stimulated hexose transport in rat skeletal muscle Biochemical Pharmacology. 38: 2655-2661. PMID 2669764 DOI: 10.1016/0006-2952(89)90551-0  0.062
2014 Jeffery S, Nathan C. Ethical Decisions: Stress and Distress in Medicine First Do No Self Harm: Understanding and Promoting Physician Stress Resilience. DOI: 10.1093/acprof:oso/9780195383263.003.0016  0.059
1973 Schaison G, Nathan C, Gilbert Dreyfus. Present diagnosis and treatment of diabetes insipidus. Report of ten cases Semaine Des Hopitaux. 49: 2825-2832. PMID 4362576  0.059
1989 Nathan C. Patients' rights in a Third World Southern African country, with special reference to Bophuthatswana: Is there any potential for privatisation? Medicine and Law. 7: 585-593. PMID 2495398  0.054
2020 Casanova JL, Holtzman DM, Kaech SM, Lanier LL, Nathan CF, Rudensky AY, Tuveson D, Wolchok JD. Immigration in science. The Journal of Experimental Medicine. 217. PMID 33057576 DOI: 10.1084/jem.20202055  0.049
1978 Fondarai J, Crocq L, Nathan C. Co-operative clinical trials of Arcalion. Assessment of its potency in astheno-depressive syndromes through statistical exploitation of a self rating scale and of a clinical rating scale Psychologie Medicale. 10: 2103-2114.  0.049
2011 Nathan C. Need There be a Defence of Equality? Winner of the 2010 Postgraduate Essay Prize Res Publica. 17: 211-225. DOI: 10.1007/s11158-011-9156-0  0.048
2021 Calderón F, Ballell L, Barros D, Bilbe G, Cammack N, Gabarró R, Halsey A, Heaton PM, Kang G, Mizrahi V, Nathan C, Strange ME, Williams PM, Winzeler EA, Fairlamb AH. Tres Cantos Open Lab: celebrating a decade of innovation in collaboration to combat endemic infectious diseases. Nature Reviews. Drug Discovery. PMID 34471283 DOI: 10.1038/d41573-021-00143-2  0.042
1974 Schaison G, Nathan C, Russo F. Results after several years of surgically treated thyrotoxicosis. With reference to 82 cases of Graves Basedow's disease Annales D'Endocrinologie. 35: 56-59. PMID 4479478  0.037
1989 Nathan C. Ethical and legal aspects to death: The burial Medicine and Law. 8: 445-454. PMID 2517967  0.035
1970 Laroche C, Nathan C. Lipo-mobilizing factor of pituitary origin Pathologie Biologie. 18: 765-773. PMID 4318643  0.035
1980 Nathan C. Nonwovens: the increasingly vital role of skilful marketing .  0.032
1990 Sasson S, Kunievsky B, Nathan C, Ceras E. On the role of 5-hydroxytryptamine in the peripheral action of fenfluramine: studies with the isolated rat soleus muscle Biochemical Pharmacology. 39: 965-968. PMID 2178612 DOI: 10.1016/0006-2952(90)90215-7  0.031
1989 Nathan C. Introduction to congress and the International Centre of Medicine and Law Medicine and Law. 7: 403-408. PMID 2493544  0.03
2017 Nathan C, Nussenzweig MC, Pulvirenti T. JEM Advisory Editorial Board: Increasing diversity. The Journal of Experimental Medicine. PMID 28747425 DOI: 10.1084/jem.20171220  0.027
1996 Pardes H, Nathan C. The Columbia-Cornell alliance: A strategic response to a changing health care environment Journal of the American Medical Association. 276: 1769-1771. PMID 8940328  0.027
1989 Derôme-Tremblay M, Nathan C. Fenfluramine studies Science. 243: 991. PMID 2922597  0.026
1989 Derôme-Tremblay M, Nathan C. Fenfluramine studies [1] Science. 243: 991.  0.026
2017 Nathan CF, Nussenzweig MC, Pulvirenti T. A time of change. The Journal of Experimental Medicine. 214: 1-2. PMID 28043986 DOI: 10.1084/jem.20162116  0.019
1985 Cordell AS, Nathan C, Krymow VP. Group counseling for children adopted at older ages Child Welfare. 64: 113-124. PMID 3979159  0.017
1984 Dumez Y, Nathan C, Henrion R. Antenatal diagnosis and foetal surgery Revue Du Praticien. 34: 3345-3349. PMID 6523013  0.016
1996 Pogue VA, Ellis C, Nathan C, Francis CK. The relationship of gender and risk factors for renal disease in urban african american hypertensive patients Journal of Investigative Medicine. 44.  0.016
1987 Nathan C. Dexfenfluramine hydrochloride Drugs of the Future. 12: 845-848.  0.015
2005 Leonard, Nathan C. "A glimpse of the eternal" Midwest Quarterly. 46: 413-415.  0.013
2012 Nathan C. The value of experience: What post World War II settlements teach us about reparations Colonialism, Slavery, Reparations and Trade: Remedying the Past?. 209-219. DOI: 10.4324/9780203357293  0.012
1974 Schaison G, Croisier JC, Nathan C, Dreyfus G. Trial of sulpiride therapy in 9 cases of acromegaly Annales D'Endocrinologie. 35: 103-110. PMID 4417658  0.01
1996 Nathan C, Betmouni R. MELPHALAN: avoid with food [2] Pharmaceutical Journal. 257: 264.  0.01
1985 Nathan C. Has linen reached its peak? .  0.01
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