Erik Falck-Pedersen - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Immunology, Microbiology Biology

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Lam E, Falck-Pedersen E. Unabated adenovirus replication following activation of the cGAS/STING-dependent antiviral response in human cells. Journal of Virology. 88: 14426-39. PMID 25297994 DOI: 10.1128/JVI.02608-14  0.76
2014 Janovitz T, Sadelain M, Falck-Pedersen E. Adeno-associated virus type 2 preferentially integrates single genome copies with defined breakpoints. Virology Journal. 11: 15. PMID 24468291 DOI: 10.1186/1743-422X-11-15  0.76
2014 Janovitz T, Oliveira T, Sadelain M, Falck-Pedersen E. Highly divergent integration profile of adeno-associated virus serotype 5 revealed by high-throughput sequencing. Journal of Virology. 88: 2481-8. PMID 24335317 DOI: 10.1128/JVI.03419-13  0.76
2014 Lam E, Stein S, Falck-Pedersen E. Adenovirus detection by the cGAS/STING/TBK1 DNA sensing cascade. Journal of Virology. 88: 974-81. PMID 24198409 DOI: 10.1128/JVI.02702-13  0.76
2013 Janovitz T, Klein IA, Oliveira T, Mukherjee P, Nussenzweig MC, Sadelain M, Falck-Pedersen E. High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration. Journal of Virology. 87: 8559-68. PMID 23720718 DOI: 10.1128/JVI.01135-13  0.76
2012 Stein SC, Lam E, Falck-Pedersen E. Cell-specific regulation of nucleic acid sensor cascades: a controlling interest in the antiviral response. Journal of Virology. 86: 13303-12. PMID 23015711 DOI: 10.1128/JVI.02296-12  0.76
2012 Stein SC, Falck-Pedersen E. Sensing adenovirus infection: activation of interferon regulatory factor 3 in RAW 264.7 cells. Journal of Virology. 86: 4527-37. PMID 22345436 DOI: 10.1128/JVI.07071-11  0.76
2009 Schoggins JW, Falck-Pedersen E. Serotype 5 Adenovirus fiber (F7F41S) chimeric vectors incur packaging deficiencies when targeting peptides are inserted into Ad41 short fiber. Virology. 395: 10-20. PMID 19782383 DOI: 10.1016/j.virol.2009.08.041  0.76
2009 Diaz F, Gravotta D, Deora A, Schreiner R, Schoggins J, Falck-Pedersen E, Rodriguez-Boulan E. Clathrin adaptor AP1B controls adenovirus infectivity of epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 11143-8. PMID 19549835 DOI: 10.1073/pnas.0811227106  0.76
2009 Nociari M, Ocheretina O, Murphy M, Falck-Pedersen E. Adenovirus induction of IRF3 occurs through a binary trigger targeting Jun N-terminal kinase and TBK1 kinase cascades and type I interferon autocrine signaling. Journal of Virology. 83: 4081-91. PMID 19211767 DOI: 10.1128/JVI.02591-08  0.76
2007 Gall J, Schoggins J, Falck-Pedersen E. Adenovirus capsid chimeras: fiber terminal exon insertions/gene replacements in the major late transcription unit. Methods in Molecular Medicine. 130: 107-23. PMID 17401167  0.76
2007 Murphy M, Gomos-Klein J, Stankic M, Falck-Pedersen E. Adeno-associated virus type 2 p5 promoter: a rep-regulated DNA switch element functioning in transcription, replication, and site-specific integration. Journal of Virology. 81: 3721-30. PMID 17267512 DOI: 10.1128/JVI.02693-06  0.76
2007 Nociari M, Ocheretina O, Schoggins JW, Falck-Pedersen E. Sensing infection by adenovirus: Toll-like receptor-independent viral DNA recognition signals activation of the interferon regulatory factor 3 master regulator. Journal of Virology. 81: 4145-57. PMID 17251283 DOI: 10.1128/JVI.02685-06  0.76
2006 Schoggins JW, Falck-Pedersen E. Fiber and penton base capsid modifications yield diminished adenovirus type 5 transduction and proinflammatory gene expression with retention of antigen-specific humoral immunity. Journal of Virology. 80: 10634-44. PMID 16943295 DOI: 10.1128/JVI.01359-06  0.76
2005 Schoggins JW, Nociari M, Philpott N, Falck-Pedersen E. Influence of fiber detargeting on adenovirus-mediated innate and adaptive immune activation. Journal of Virology. 79: 11627-37. PMID 16140740 DOI: 10.1128/JVI.79.18.11627-11637.2005  0.76
2004 Hamilton H, Gomos J, Berns KI, Falck-Pedersen E. Adeno-associated virus site-specific integration and AAVS1 disruption. Journal of Virology. 78: 7874-82. PMID 15254160 DOI: 10.1128/JVI.78.15.7874-7882.2004  0.76
2004 Philpott NJ, Nociari M, Elkon KB, Falck-Pedersen E. Adenovirus-induced maturation of dendritic cells through a PI3 kinase-mediated TNF-alpha induction pathway. Proceedings of the National Academy of Sciences of the United States of America. 101: 6200-5. PMID 15071185 DOI: 10.1073/pnas.0308368101  0.76
2004 Philpott NJ, Gomos J, Falck-Pedersen E. Transgene expression after rep-mediated site-specific integration into chromosome 19. Human Gene Therapy. 15: 47-61. PMID 14965377 DOI: 10.1089/10430340460732454  0.76
2003 Schoggins JW, Gall JG, Falck-Pedersen E. Subgroup B and F fiber chimeras eliminate normal adenovirus type 5 vector transduction in vitro and in vivo. Journal of Virology. 77: 1039-48. PMID 12502819 DOI: 10.1128/JVI.77.2.1039-1048.2003  0.76
2002 Philpott NJ, Gomos J, Berns KI, Falck-Pedersen E. A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19. Proceedings of the National Academy of Sciences of the United States of America. 99: 12381-5. PMID 12221283 DOI: 10.1073/pnas.182430299  0.76
2002 Hu X, Herrero C, Li WP, Antoniv TT, Falck-Pedersen E, Koch AE, Woods JM, Haines GK, Ivashkiv LB. Sensitization of IFN-gamma Jak-STAT signaling during macrophage activation. Nature Immunology. 3: 859-66. PMID 12172544 DOI: 10.1038/ni828  0.76
2002 Philpott NJ, Giraud-Wali C, Dupuis C, Gomos J, Hamilton H, Berns KI, Falck-Pedersen E. Efficient integration of recombinant adeno-associated virus DNA vectors requires a p5-rep sequence in cis. Journal of Virology. 76: 5411-21. PMID 11991970 DOI: 10.1128/JVI.76.11.5411-5421.2002  0.76
2001 Trevejo JM, Marino MW, Philpott N, Josien R, Richards EC, Elkon KB, Falck-Pedersen E. TNF-alpha -dependent maturation of local dendritic cells is critical for activating the adaptive immune response to virus infection. Proceedings of the National Academy of Sciences of the United States of America. 98: 12162-7. PMID 11593031 DOI: 10.1073/pnas.211423598  0.76
2001 Peng Y, Falck-Pedersen E, Elkon KB. Variation in adenovirus transgene expression between BALB/c and C57BL/6 mice is associated with differences in interleukin-12 and gamma interferon production and NK cell activation Journal of Virology. 75: 4540-4550. PMID 11312324 DOI: 10.1128/JVI.75.10.4540-4550.2001  0.76
2000 Peng Y, Falck-Pedersen E, Elkon KB. Soluble CD8 attenuates cytotoxic T cell responses against replication- defective adenovirus affording transprotection of transgenes in vivo Journal of Immunology. 165: 1470-1478. PMID 10903752  0.76
2000 Nicolás AL, Munz PL, Falck-Pedersen E, Young CS. Creation and repair of specific DNA double-strand breaks in vivo following infection with adenovirus vectors expressing Saccharomyces cerevisiae HO endonuclease. Virology. 266: 211-24. PMID 10612676 DOI: 10.1006/viro.1999.0062  0.76
1999 Miyazawa N, Leopold PL, Hackett NR, Ferris B, Worgall S, Falck-Pedersen E, Crystal RG. Fiber swap between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors. Journal of Virology. 73: 6056-65. PMID 10364358  0.76
1999 Peng Y, Trevejo J, Zhou J, Marino MW, Crystal RG, Falck-Pedersen E, Elkon KB. Inhibition of tumor necrosis factor alpha by an adenovirus-encoded soluble fusion protein extends transgene expression in the liver and lung Journal of Virology. 73: 5098-5109. PMID 10233973  0.76
1999 Kaner RJ, Worgall S, Leopold PL, Stolze E, Milano E, Hidaka C, Ramalingam R, Hackett NR, Singh R, Bergelson J, Finberg R, Falck-Pedersen E, Crystal RG. Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor. American Journal of Respiratory Cell and Molecular Biology. 20: 361-70. PMID 10030833 DOI: 10.1165/ajrcmb.20.3.3398  0.76
1998 Gall JG, Crystal RG, Falck-Pedersen E. Construction and characterization of hexon-chimeric adenoviruses: specification of adenovirus serotype. Journal of Virology. 72: 10260-4. PMID 9811772  0.76
1997 Abrahamsen K, Kong HL, Mastrangeli A, Brough D, Lizonova A, Crystal RG, Falck-Pedersen E. Construction of an adenovirus type 7a E1A- vector Journal of Virology. 71: 8946-8951. PMID 9343264  0.76
1997 Elkon KB, Liu CC, Gall JG, Trevejo J, Marino MW, Abrahamsen KA, Song X, Zhou JL, Old LJ, Crystal RG, Falck-Pedersen E. Tumor necrosis factor alpha plays a central role in immune-mediated clearance of adenoviral vectors. Proceedings of the National Academy of Sciences of the United States of America. 94: 9814-9. PMID 9275208 DOI: 10.1073/pnas.94.18.9814  0.76
1997 Prescott JC, Liu L, Falck-Pedersen E. Sequence-mediated regulation of adenovirus gene expression by repression of mRNA accumulation Molecular and Cellular Biology. 17: 2207-2216. PMID 9121471  0.76
1997 Mack CA, Song WR, Carpenter H, Wickham TJ, Kovesdi I, Harvey BG, Magovern CJ, Isom OW, Rosengart T, Falck-Pedersen E, Hackett NR, Crystal RG, Mastrangeli A. Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype Human Gene Therapy. 8: 99-109. PMID 8989999  0.76
1997 Worgall S, Wolff G, Falck-Pedersen E, Crystal RG. Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration. Human Gene Therapy. 8: 37-44. PMID 8989993 DOI: 10.1089/hum.1997.8.1-37  0.76
1996 Yoon SO, Lois C, Alvirez M, Alvarez-Buylla A, Falck-Pedersen E, Chao MV. Adenovirus-mediated gene delivery into neuronal precursors of the adult mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 93: 11974-9. PMID 8876247 DOI: 10.1073/pnas.93.21.11974  0.76
1996 Kass-Eisler A, Leinwand L, Gall J, Bloom B, Falck-Pedersen E. Circumventing the immune response to adenovirus-mediated gene therapy Gene Therapy. 3: 154-162. PMID 8867863  0.76
1996 Mastrangeli A, Harvey BG, Yao J, Wolff G, Kovesdi I, Crystal RG, Falck-Pedersen E. "Sero-switch" adenovirus-mediated in vivo gene transfer: Circumvention of anti-Adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype Human Gene Therapy. 7: 79-87. PMID 8825871  0.76
1996 Gall J, Kass-Eisler A, Leinwand L, Falck-Pedersen E. Adenovirus type 5 and 7 capsid chimera: Fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes Journal of Virology. 70: 2116-2123. PMID 8642632  0.76
1996 Yeaman C, Heinflink M, Falck-Pedersen E, Rodriguez-Boulan E, Gershengorn MC. Polarity of TRH receptors in transfected MDCK cells is independent of endocytosis signals and G protein coupling. The American Journal of Physiology. 270: C753-62. PMID 8638654  0.76
1996 Wolff G, Mastrangeli A, Heinflink M, Falck-Pedersen E, Gershengorn MC, Crystal RG. Ectopic expression of thyrotropin releasing hormone (TRH) receptors in liver modulates organ function to regulate blood glucose by TRH Nature Genetics. 12: 274-279. PMID 8589718 DOI: 10.1038/ng0396-274  0.76
1994 Falck-Pedersen E, Heinflink M, Alvira M, Nussenzveig DR, Gershengorn MC. Expression of thyrotropin-releasing hormone receptors by adenovirus-mediated gene transfer reveals that thyrotropin-releasing hormone desensitization is cell specific Molecular Pharmacology. 45: 684-689. PMID 8183247  0.76
1994 Gershengorn MC, Heinflink M, Nussenzveig DR, Hinkle PM, Falck-Pedersen E. Thyrotropin-releasing Hormone (TRH) Receptor Number Determines the Size of the TRH-responsive Phosphoinositide Pool: Demonstration using controlled expression of TRH receptors by adenovirus mediated gene transfer Journal of Biological Chemistry. 269: 6779-6783. PMID 8120038  0.76
1994 Prescott J, Falck-Pedersen E. Sequence elements upstream of the 3' cleavage site confer substrate strength to the adenovirus L1 and L3 polyadenylation sites Molecular and Cellular Biology. 14: 4682-4693. PMID 7911973  0.76
1994 Kass-Eisler A, Falck-Pedersen E, Elfenbein DH, Alvira M, Buttrick PM, Leinwand LA. The impact of developmental stage, route of administration and the immune system on adenovirus-mediated gene transfer Gene Therapy. 1: 395-402. PMID 7584105  0.76
1993 Tantravahi J, Alvira M, Falck-Pedersen E. Characterization of the Mouse βmaj Globin Transcription Termination Region: A Spacing Sequence Is Required between the Poly(A) Signal Sequence and Multiple Downstream Termination Elements Molecular and Cellular Biology. 13: 578-587. PMID 8417354  0.76
1993 Kass-Eisler A, Falck-Pedersen E, Alvira M, Rivera J, Buttrick PM, Wittenberg BA, Cipriani L, Leinwand LA. Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo Proceedings of the National Academy of Sciences of the United States of America. 90: 11498-11502. PMID 8265580  0.76
1993 Edwalds-Gilbert G, Prescott J, Falck-Pedersen E. 3' RNA processing efficiency plays a primary role in generating termination-competent RNA polymerase II elongation complexes Molecular and Cellular Biology. 13: 3472-3480. PMID 7684499  0.76
1992 Prescott JC, Falck-Pedersen E. Varied poly(A) site efficiency in the adenovirus major late transcription unit Journal of Biological Chemistry. 267: 8175-8181. PMID 1575826  0.76
1991 DeZazzo JD, Falck-Pedersen E, Imperiale MJ. Sequences Regulating Temporal Poly(A) Site Switching in the Adenovirus Major Late Transcription Unit Molecular and Cellular Biology. 11: 5977-5984. PMID 1944273  0.76
1989 Gulati P, Falck-Pedersen E, Siskind GW. Regulation of antibody secretion by hybridoma cells. II. mechanism of idiotype-induced suppression of antibody secretion by hybridoma cells Cellular Immunology. 123: 276-282. PMID 2529040 DOI: 10.1016/0008-8749(89)90288-8  0.76
1987 Logan J, Falck-Pedersen E, Darnell JE, Shenk T. A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene. Proceedings of the National Academy of Sciences of the United States of America. 84: 8306-10. PMID 3479794  0.76
1985 Falck-Pedersen E, Logan J, Shenk T, Darnell JE. Transcription termination within the E1A gene of adenovirus induced by insertion of the mouse beta-major globin terminator element. Cell. 40: 897-905. PMID 2580640 DOI: 10.1016/0092-8674(85)90349-6  0.76
1984 Citron B, Falck-Pedersen E, Salditt-Georgieff M, Darnell JE. Transcription termination occurs within a 1000 base pair region downstream from the poly(A) site of the mouse beta-globin (major) gene. Nucleic Acids Research. 12: 8723-31. PMID 6095210 DOI: 10.1093/nar/12.22.8723  0.76
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