Victor H. Engelhard - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Immunology, Microbiology Biology

192 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Leick KM, Rodriguez AB, Melssen MM, Benamar M, Lindsay RS, Eki R, Du KP, Parlak M, Abbas T, Engelhard VH, Slingluff CL. The Barrier Molecules Junction Plakoglobin, Filaggrin, and Dystonin Play Roles in Melanoma Growth and Angiogenesis. Annals of Surgery. PMID 31425296 DOI: 10.1097/SLA.0000000000003522  0.36
2019 Leick KM, Pinczewski J, Mauldin IS, Young SJ, Deacon DH, Woods AN, Bosenberg MW, Engelhard VH, Slingluff CL. Patterns of immune-cell infiltration in murine models of melanoma: roles of antigen and tissue site in creating inflamed tumors. Cancer Immunology, Immunotherapy : Cii. PMID 31134297 DOI: 10.1007/s00262-019-02345-5  0.36
2019 Berendam SJ, Koeppel AF, Godfrey NR, Rouhani SJ, Woods AN, Rodriguez AB, Peske JD, Cummings KL, Turner SD, Engelhard VH. Comparative Transcriptomic Analysis Identifies a Range of Immunologically Related Functional Elaborations of Lymph Node Associated Lymphatic and Blood Endothelial Cells. Frontiers in Immunology. 10: 816. PMID 31057546 DOI: 10.3389/fimmu.2019.00816  0.68
2018 Melssen MM, Olson W, Wages NA, Capaldo BJ, Mauldin IS, Mahmutovic A, Hutchison C, Melief CJM, Bullock TN, Engelhard VH, Slingluff CL. Formation and phenotypic characterization of CD49a, CD49b and CD103 expressing CD8 T cell populations in human metastatic melanoma. Oncoimmunology. 7: e1490855. PMID 30288359 DOI: 10.1080/2162402X.2018.1490855  0.36
2018 Rodriguez AB, Peske JD, Engelhard VH. Identification and Characterization of Tertiary Lymphoid Structures in Murine Melanoma. Methods in Molecular Biology (Clifton, N.J.). 1845: 241-257. PMID 30141017 DOI: 10.1007/978-1-4939-8709-2_14  0.68
2018 Engelhard VH, Rodriguez AB, Mauldin IS, Woods AN, Peske JD, Slingluff CL. Immune Cell Infiltration and Tertiary Lymphoid Structures as Determinants of Antitumor Immunity. Journal of Immunology (Baltimore, Md. : 1950). 200: 432-442. PMID 29311385 DOI: 10.4049/jimmunol.1701269  0.68
2017 Woods AN, Wilson AL, Srivinisan N, Zeng J, Dutta AB, Peske JD, Tewalt EF, Gregg RK, Ferguson AR, Engelhard VH. Differential expression of homing receptor ligands on tumor associated vasculature that control CD8 effector T cell entry. Cancer Immunology Research. PMID 29097419 DOI: 10.1158/2326-6066.CIR-17-0190  0.68
2015 Peske JD, Woods AB, Engelhard VH. Control of CD8 T-Cell Infiltration into Tumors by Vasculature and Microenvironment. Advances in Cancer Research. 128: 263-307. PMID 26216636 DOI: 10.1016/bs.acr.2015.05.001  0.96
2015 Peske JD, Thompson ED, Gemta L, Baylis RA, Fu YX, Engelhard VH. Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity. Nature Communications. 6: 7114. PMID 25968334 DOI: 10.1038/ncomms8114  0.96
2015 Rouhani SJ, Eccles JD, Riccardi P, Peske JD, Tewalt EF, Cohen JN, Liblau R, Mäkinen T, Engelhard VH. Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction. Nature Communications. 6: 6771. PMID 25857745 DOI: 10.1038/ncomms7771  0.96
2014 Rouhani SJ, Eccles JD, Tewalt EF, Engelhard VH. Regulation of T-cell Tolerance by Lymphatic Endothelial Cells. Journal of Clinical & Cellular Immunology. 5. PMID 25580369 DOI: 10.4172/2155-9899.1000242  0.6
2014 Zarling AL, Obeng RC, Desch AN, Pinczewski J, Cummings KL, Deacon DH, Conaway M, Slingluff CL, Engelhard VH. MHC-restricted phosphopeptides from insulin receptor substrate-2 and CDC25b offer broad-based immunotherapeutic agents for cancer. Cancer Research. 74: 6784-95. PMID 25297629 DOI: 10.1158/0008-5472.CAN-14-0043  0.96
2014 Eby JM, Kang HK, Klarquist J, Chatterjee S, Mosenson JA, Nishimura MI, Garrett-Mayer E, Longley BJ, Engelhard VH, Mehrotra S, Le Poole IC. Immune responses in a mouse model of vitiligo with spontaneous epidermal de- and repigmentation. Pigment Cell & Melanoma Research. 27: 1075-85. PMID 24935676 DOI: 10.1111/pcmr.12284  0.96
2014 Cohen JN, Tewalt EF, Rouhani SJ, Buonomo EL, Bruce AN, Xu X, Bekiranov S, Fu YX, Engelhard VH. Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment. Plos One. 9: e87740. PMID 24503860 DOI: 10.1371/journal.pone.0087740  0.96
2013 Rival C, Wheeler K, Jeffrey S, Qiao H, Luu B, Tewalt EF, Engelhard VH, Tardif S, Hardy D, del Rio R, Teuscher C, Tung K. Regulatory T cells and vasectomy. Journal of Reproductive Immunology. 100: 66-75. PMID 24080233 DOI: 10.1016/j.jri.2013.08.004  0.96
2013 Cobbold M, De La Peña H, Norris A, Polefrone JM, Qian J, English AM, Cummings KL, Penny S, Turner JE, Cottine J, Abelin JG, Malaker SA, Zarling AL, Huang HW, Goodyear O, ... ... Engelhard VH, et al. MHC class I-associated phosphopeptides are the targets of memory-like immunity in leukemia. Science Translational Medicine. 5: 203ra125. PMID 24048523 DOI: 10.1126/scitranslmed.3006061  0.96
2013 Brinkman CC, Peske JD, Engelhard VH. Peripheral tissue homing receptor control of naïve, effector, and memory CD8 T cell localization in lymphoid and non-lymphoid tissues. Frontiers in Immunology. 4: 241. PMID 23966998 DOI: 10.3389/fimmu.2013.00241  0.96
2013 Brinkman CC, Rouhani SJ, Srinivasan N, Engelhard VH. Peripheral tissue homing receptors enable T cell entry into lymph nodes and affect the anatomical distribution of memory cells. Journal of Immunology (Baltimore, Md. : 1950). 191: 2412-25. PMID 23926324 DOI: 10.4049/jimmunol.1300651  0.96
2013 Engels B, Engelhard VH, Sidney J, Sette A, Binder DC, Liu RB, Kranz DM, Meredith SC, Rowley DA, Schreiber H. Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity. Cancer Cell. 23: 516-26. PMID 23597565 DOI: 10.1016/j.ccr.2013.03.018  0.96
2013 Brinkman CC, Rouhani SJ, Srinivasan N, Engelhard VH. Peripheral tissue homing receptors enable T cell entry into lymph nodes and affect the anatomical distribution of memory cells (J. Immunol. (2013) 191, (2412-2425) 10.4049/jimmunol.1390066) Journal of Immunology. 191: 6292. DOI: 10.4049/jimmunol.1390066  0.96
2012 Tewalt EF, Cohen JN, Rouhani SJ, Engelhard VH. Lymphatic endothelial cells - key players in regulation of tolerance and immunity. Frontiers in Immunology. 3: 305. PMID 23060883 DOI: 10.3389/fimmu.2012.00305  0.96
2012 Tewalt EF, Cohen JN, Rouhani SJ, Guidi CJ, Qiao H, Fahl SP, Conaway MR, Bender TP, Tung KS, Vella AT, Adler AJ, Chen L, Engelhard VH. Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells. Blood. 120: 4772-82. PMID 22993390 DOI: 10.1182/blood-2012-04-427013  0.96
2010 Thompson ED, Enriquez HL, Fu YX, Engelhard VH. Tumor masses support naive T cell infiltration, activation, and differentiation into effectors. The Journal of Experimental Medicine. 207: 1791-804. PMID 20660615 DOI: 10.1084/jem.20092454  0.96
2010 Li Y, Depontieu FR, Sidney J, Salay TM, Engelhard VH, Hunt DF, Sette A, Topalian SL, Mariuzza RA. Structural basis for the presentation of tumor-associated MHC class II-restricted phosphopeptides to CD4+ T cells. Journal of Molecular Biology. 399: 596-603. PMID 20417641 DOI: 10.1016/j.jmb.2010.04.037  0.96
2010 Cohen JN, Guidi CJ, Tewalt EF, Qiao H, Rouhani SJ, Ruddell A, Farr AG, Tung KS, Engelhard VH. Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation. The Journal of Experimental Medicine. 207: 681-8. PMID 20308365 DOI: 10.1084/jem.20092465  0.96
2010 Ferguson AR, Engelhard VH. CD8 T cells activated in distinct lymphoid organs differentially express adhesion proteins and coexpress multiple chemokine receptors. Journal of Immunology (Baltimore, Md. : 1950). 184: 4079-86. PMID 20212096 DOI: 10.4049/jimmunol.0901903  0.96
2010 Hulse KE, Reefer AJ, Engelhard VH, Patrie JT, Ziegler SF, Chapman MD, Woodfolk JA. Targeting allergen to FcgammaRI reveals a novel T(H)2 regulatory pathway linked to thymic stromal lymphopoietin receptor. The Journal of Allergy and Clinical Immunology. 125: 247-56.e1-8. PMID 20109752 DOI: 10.1016/j.jaci.2009.10.027  0.96
2010 Gregg RK, Nichols L, Chen Y, Lu B, Engelhard VH. Mechanisms of spatial and temporal development of autoimmune vitiligo in tyrosinase-specific TCR transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 184: 1909-17. PMID 20083666 DOI: 10.4049/jimmunol.0902778  0.96
2009 Depontieu FR, Qian J, Zarling AL, McMiller TL, Salay TM, Norris A, English AM, Shabanowitz J, Engelhard VH, Hunt DF, Topalian SL. Identification of tumor-associated, MHC class II-restricted phosphopeptides as targets for immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 106: 12073-8. PMID 19581576 DOI: 10.1073/pnas.0903852106  0.96
2009 Ostankovitch M, Altrich-Vanlith M, Robila V, Engelhard VH. N-glycosylation enhances presentation of a MHC class I-restricted epitope from tyrosinase. Journal of Immunology (Baltimore, Md. : 1950). 182: 4830-5. PMID 19342661 DOI: 10.4049/jimmunol.0802902  0.96
2009 Nicholls S, Piper KP, Mohammed F, Dafforn TR, Tenzer S, Salim M, Mahendra P, Craddock C, van Endert P, Schild H, Cobbold M, Engelhard VH, Moss PA, Willcox BE. Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition. Proceedings of the National Academy of Sciences of the United States of America. 106: 3889-94. PMID 19234124 DOI: 10.1073/pnas.0900411106  0.96
2008 Robila V, Ostankovitch M, Altrich-Vanlith ML, Theos AC, Drover S, Marks MS, Restifo N, Engelhard VH. MHC class II presentation of gp100 epitopes in melanoma cells requires the function of conventional endosomes and is influenced by melanosomes. Journal of Immunology (Baltimore, Md. : 1950). 181: 7843-52. PMID 19017974  0.96
2008 Mohammed F, Cobbold M, Zarling AL, Salim M, Barrett-Wilt GA, Shabanowitz J, Hunt DF, Engelhard VH, Willcox BE. Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self. Nature Immunology. 9: 1236-43. PMID 18836451 DOI: 10.1038/ni.1660  0.96
2008 Brinkman CC, Sheasley-O'Neill SL, Ferguson AR, Engelhard VH. Activated CD8 T cells redistribute to antigen-free lymph nodes and exhibit effector and memory characteristics. Journal of Immunology (Baltimore, Md. : 1950). 181: 1814-24. PMID 18641319  0.96
2008 Ferguson AR, Nichols LA, Zarling AL, Thompson ED, Brinkman CC, Hargadon KM, Bullock TN, Engelhard VH. Strategies and challenges in eliciting immunity to melanoma. Immunological Reviews. 222: 28-42. PMID 18363993 DOI: 10.1111/j.1600-065X.2008.00620.x  0.96
2008 Lengagne R, Graff-Dubois S, Garcette M, Renia L, Kato M, Guillet JG, Engelhard VH, Avril MF, Abastado JP, Prévost-Blondel A. Distinct role for CD8 T cells toward cutaneous tumors and visceral metastases. Journal of Immunology (Baltimore, Md. : 1950). 180: 130-7. PMID 18097012  0.96
2008 Hulse KE, Reefer AJ, Engelhard VH, Satinover SM, Patrie JT, Chapman MD, Woodfolk JA. Targeting Fel d 1 to FcgammaRI induces a novel variation of the T(H)2 response in subjects with cat allergy. The Journal of Allergy and Clinical Immunology. 121: 756-762.e4. PMID 18086491 DOI: 10.1016/j.jaci.2007.10.016  0.96
2007 Engelhard VH. The contributions of mass spectrometry to understanding of immune recognition by T lymphocytes. International Journal of Mass Spectrometry. 259: 32-39. PMID 18167512 DOI: 10.1016/j.ijms.2006.08.009  0.96
2007 Hunt DF, Henderson RA, Shabanowitz J, Sakaguchi K, Michel H, Sevilir N, Cox AL, Appella E, Engelhard VH. Pillars article: Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry. Science 1992. 255: 1261-1263. Journal of Immunology (Baltimore, Md. : 1950). 179: 2669-71. PMID 17709476  0.96
2007 Nichols LA, Chen Y, Colella TA, Bennett CL, Clausen BE, Engelhard VH. Deletional self-tolerance to a melanocyte/melanoma antigen derived from tyrosinase is mediated by a radio-resistant cell in peripheral and mesenteric lymph nodes. Journal of Immunology (Baltimore, Md. : 1950). 179: 993-1003. PMID 17617591  0.96
2007 Li L, Huang L, Sung SS, Lobo PI, Brown MG, Gregg RK, Engelhard VH, Okusa MD. NKT cell activation mediates neutrophil IFN-gamma production and renal ischemia-reperfusion injury. Journal of Immunology (Baltimore, Md. : 1950). 178: 5899-911. PMID 17442974  0.96
2007 Sheasley-O'Neill SL, Brinkman CC, Ferguson AR, Dispenza MC, Engelhard VH. Dendritic cell immunization route determines integrin expression and lymphoid and nonlymphoid tissue distribution of CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 1512-22. PMID 17237400  0.96
2006 Lappas CM, Day YJ, Marshall MA, Engelhard VH, Linden J. Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation. The Journal of Experimental Medicine. 203: 2639-48. PMID 17088433 DOI: 10.1084/jem.20061097  0.96
2006 Hargadon KM, Brinkman CC, Sheasley-O'neill SL, Nichols LA, Bullock TN, Engelhard VH. Incomplete differentiation of antigen-specific CD8 T cells in tumor-draining lymph nodes. Journal of Immunology (Baltimore, Md. : 1950). 177: 6081-90. PMID 17056534  0.96
2006 Altrich-VanLith ML, Ostankovitch M, Polefrone JM, Mosse CA, Shabanowitz J, Hunt DF, Engelhard VH. Processing of a class I-restricted epitope from tyrosinase requires peptide N-glycanase and the cooperative action of endoplasmic reticulum aminopeptidase 1 and cytosolic proteases. Journal of Immunology (Baltimore, Md. : 1950). 177: 5440-50. PMID 17015730  0.96
2006 Zarling AL, Polefrone JM, Evans AM, Mikesh LM, Shabanowitz J, Lewis ST, Engelhard VH, Hunt DF. Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 103: 14889-94. PMID 17001009 DOI: 10.1073/pnas.0604045103  0.96
2006 Slingluff CL, Chianese-Bullock KA, Bullock TN, Grosh WW, Mullins DW, Nichols L, Olson W, Petroni G, Smolkin M, Engelhard VH. Immunity to melanoma antigens: from self-tolerance to immunotherapy. Advances in Immunology. 90: 243-95. PMID 16730266 DOI: 10.1016/S0065-2776(06)90007-8  0.96
2006 Slingluff CL, Engelhard VH, Ferrone S. Peptide and dendritic cell vaccines. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 2342s-2345s. PMID 16609056 DOI: 10.1158/1078-0432.CCR-05-2541  0.96
2006 Mullins DW, Engelhard VH. Limited infiltration of exogenous dendritic cells and naive T cells restricts immune responses in peripheral lymph nodes. Journal of Immunology (Baltimore, Md. : 1950). 176: 4535-42. PMID 16585543  0.96
2006 Brickner AG, Evans AM, Mito JK, Xuereb SM, Feng X, Nishida T, Fairfull L, Ferrell RE, Foon KA, Hunt DF, Shabanowitz J, Engelhard VH, Riddell SR, Warren EH. The PANE1 gene encodes a novel human minor histocompatibility antigen that is selectively expressed in B-lymphoid cells and B-CLL. Blood. 107: 3779-86. PMID 16391015 DOI: 10.1182/blood-2005-08-3501  0.96
2006 Engelhard VH, Altrich-Vanlith M, Ostankovitch M, Zarling AL. Post-translational modifications of naturally processed MHC-binding epitopes. Current Opinion in Immunology. 18: 92-7. PMID 16343885 DOI: 10.1016/j.coi.2005.11.015  0.96
2005 Kharel Y, Lee S, Snyder AH, Sheasley-O'neill SL, Morris MA, Setiady Y, Zhu R, Zigler MA, Burcin TL, Ley K, Tung KS, Engelhard VH, Macdonald TL, Pearson-White S, Lynch KR. Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720. The Journal of Biological Chemistry. 280: 36865-72. PMID 16093248 DOI: 10.1074/jbc.M506293200  0.96
2005 Yamshchikov GV, Mullins DW, Chang CC, Ogino T, Thompson L, Presley J, Galavotti H, Aquila W, Deacon D, Ross W, Patterson JW, Engelhard VH, Ferrone S, Slingluff CL. Sequential immune escape and shifting of T cell responses in a long-term survivor of melanoma. Journal of Immunology (Baltimore, Md. : 1950). 174: 6863-71. PMID 15905528  0.96
2005 Ostankovitch M, Robila V, Engelhard VH. Regulated folding of tyrosinase in the endoplasmic reticulum demonstrates that misfolded full-length proteins are efficient substrates for class I processing and presentation. Journal of Immunology (Baltimore, Md. : 1950). 174: 2544-51. PMID 15728460  0.96
2004 Thompson LW, Garbee CF, Hibbitts S, Brinckerhoff LH, Pierce RA, Chianese-Bullock KA, Deacon DH, Engelhard VH, Slingluff CL. Competition among peptides in melanoma vaccines for binding to MHC molecules. Journal of Immunotherapy (Hagerstown, Md. : 1997). 27: 425-31. PMID 15534486  0.96
2004 Thompson LW, Hogan KT, Caldwell JA, Pierce RA, Hendrickson RC, Deacon DH, Settlage RE, Brinckerhoff LH, Engelhard VH, Shabanowitz J, Hunt DF, Slingluff CL. Preventing the spontaneous modification of an HLA-A2-restricted peptide at an N-terminal glutamine or an internal cysteine residue enhances peptide antigenicity. Journal of Immunotherapy (Hagerstown, Md. : 1997). 27: 177-83. PMID 15076134  0.96
2004 Hogan KT, Coppola MA, Gatlin CL, Thompson LW, Shabanowitz J, Hunt DF, Engelhard VH, Ross MM, Slingluff CL. Identification of novel and widely expressed cancer/testis gene isoforms that elicit spontaneous cytotoxic T-lymphocyte reactivity to melanoma. Cancer Research. 64: 1157-63. PMID 14871852 DOI: 10.1158/0008-5472.CAN-03-2209  0.96
2004 Engelhard VH. Creating new peptide antigens by slicing and splicing proteins. Nature Immunology. 5: 128-9. PMID 14749782 DOI: 10.1038/ni0204-128  0.96
2003 Hogan KT, Coppola MA, Gatlin CL, Thompson LW, Shabanowitz J, Hunt DF, Engelhard VH, Slingluff CL, Ross MM. Identification of a shared epitope recognized by melanoma-specific, HLA-A3-restricted cytotoxic T lymphocytes. Immunology Letters. 90: 131-5. PMID 14687714 DOI: 10.1016/j.imlet.2003.08.003  0.96
2003 Akatsuka Y, Warren EH, Gooley TA, Brickner AG, Lin MT, Hansen JA, Martin PJ, Madtes DK, Engelhard VH, Takahashi T, Riddell SR. Disparity for a newly identified minor histocompatibility antigen, HA-8, correlates with acute graft-versus-host disease after haematopoietic stem cell transplantation from an HLA-identical sibling. British Journal of Haematology. 123: 671-5. PMID 14616971 DOI: 10.1046/j.1365-2141.2003.04676.x  0.96
2003 Zarling AL, Luckey CJ, Marto JA, White FM, Brame CJ, Evans AM, Lehner PJ, Cresswell P, Shabanowitz J, Hunt DF, Engelhard VH. Tapasin is a facilitator, not an editor, of class I MHC peptide binding. Journal of Immunology (Baltimore, Md. : 1950). 171: 5287-95. PMID 14607930  0.96
2003 Slingluff CL, Petroni GR, Yamshchikov GV, Barnd DL, Eastham S, Galavotti H, Patterson JW, Deacon DH, Hibbitts S, Teates D, Neese PY, Grosh WW, Chianese-Bullock KA, Woodson EM, Wiernasz CJ, ... ... Engelhard VH, et al. Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 4016-26. PMID 14581425 DOI: 10.1200/JCO.2003.10.005  0.96
2003 Mullins DW, Sheasley SL, Ream RM, Bullock TN, Fu YX, Engelhard VH. Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control. The Journal of Experimental Medicine. 198: 1023-34. PMID 14530375 DOI: 10.1084/jem.20021348  0.96
2003 Spierings E, Brickner AG, Caldwell JA, Zegveld S, Tatsis N, Blokland E, Pool J, Pierce RA, Mollah S, Shabanowitz J, Eisenlohr LC, van Veelen P, Ossendorp F, Hunt DF, Goulmy E, ... Engelhard VH, et al. The minor histocompatibility antigen HA-3 arises from differential proteasome-mediated cleavage of the lymphoid blast crisis (Lbc) oncoprotein. Blood. 102: 621-9. PMID 12663445 DOI: 10.1182/blood-2003-01-0260  0.96
2003 Bullock TN, Mullins DW, Engelhard VH. Antigen density presented by dendritic cells in vivo differentially affects the number and avidity of primary, memory, and recall CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 1822-9. PMID 12574347  0.96
2002 Norton EJ, Diekman AB, Westbrook VA, Mullins DW, Klotz KL, Gilmer LL, Thomas TS, Wright DC, Brisker J, Engelhard VH, Flickinger CJ, Herr JC. A male genital tract-specific carbohydrate epitope on human CD52: Implications for immunocontraception Tissue Antigens. 60: 354-364. PMID 12492811 DOI: 10.1034/j.1399-0039.2002.600502.x  0.96
2002 Engelhard VH, Bullock TN, Colella TA, Sheasley SL, Mullins DW. Antigens derived from melanocyte differentiation proteins: self-tolerance, autoimmunity, and use for cancer immunotherapy. Immunological Reviews. 188: 136-46. PMID 12445287 DOI: 10.1034/j.1600-065X.2002.18812.x  0.96
2002 Lippolis JD, White FM, Marto JA, Luckey CJ, Bullock TN, Shabanowitz J, Hunt DF, Engelhard VH. Analysis of MHC class II antigen processing by quantitation of peptides that constitute nested sets. Journal of Immunology (Baltimore, Md. : 1950). 169: 5089-97. PMID 12391225  0.96
2002 Engelhard VH, Brickner AG, Zarling AL. Insights into antigen processing gained by direct analysis of the naturally processed class I MHC associated peptide repertoire. Molecular Immunology. 39: 127-37. PMID 12200045 DOI: 10.1016/S0161-5890(02)00096-2  0.96
2002 Warren EH, Otterud BE, Linterman RW, Brickner AG, Engelhard VH, Leppert MF, Martin PJ, Riddell SR. Feasibility of using genetic linkage analysis to identify the genes encoding T cell-defined minor histocompatibility antigens Tissue Antigens. 59: 293-303. PMID 12135428 DOI: 10.1034/j.1399-0039.2002.590407.x  0.96
2002 Flyer DC, Ramakrishna V, Miller C, Myers H, McDaniel M, Root K, Flournoy C, Engelhard VH, Canaday DH, Marto JA, Ross MM, Hunt DF, Shabanowitz J, White FM. Identification by mass spectrometry of CD8(+)-T-cell Mycobacterium tuberculosis epitopes within the Rv0341 gene product. Infection and Immunity. 70: 2926-32. PMID 12010981 DOI: 10.1128/IAI.70.6.2926-2932.2002  0.96
2002 Le Gal FA, Prevost-Blondel A, Lengagne R, Bossus M, Farace F, Chaboissier A, Gras-Masse H, Engelhard VH, Guillet JG, Gahéry-Ségard H. Lipopeptide-based melanoma cancer vaccine induced a strong MART-27-35-cytotoxic T lymphocyte response in a preclinal study. International Journal of Cancer. Journal International Du Cancer. 98: 221-7. PMID 11857412 DOI: 10.1002/ijc.10186  0.96
2002 Evans AM, Zarling AL, Ficarro SB, Shabanowitz J, Engelhard VH, Hunt DF. Differential comparison of phosphorylated MHC class I HLA-A2.1 Peptides from three different cancer cell lines Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 27-28.  0.96
2001 Bullock TN, Mullins DW, Colella TA, Engelhard VH. Manipulation of avidity to improve effectiveness of adoptively transferred CD8(+) T cells for melanoma immunotherapy in human MHC class I-transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 167: 5824-31. PMID 11698456  0.96
2001 Mullins DW, Bullock TN, Colella TA, Robila VV, Engelhard VH. Immune responses to the HLA-A*0201-restricted epitopes of tyrosinase and glycoprotein 100 enable control of melanoma outgrowth in HLA-A*0201-transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 167: 4853-60. PMID 11673489  0.96
2001 Slingluff C.L. J, Yamshchikov G, Neese P, Galavotti H, Eastham S, Engelhard VH, Kittlesen D, Deacon D, Hibbitts S, Grosh WW, Petroni G, Cohen R, Wiernasz C, Patterson JW, Conway BP, et al. Phase I trial of a melanoma vaccine with gp100280-288 peptide and tetanus helper peptide in adjuvant: Immunologic and clinical outcomes Clinical Cancer Research. 7: 3012-3024. PMID 11595689  0.96
2001 Pierce RA, Field ED, Mutis T, Golovina TN, Von Kap-Herr C, Wilke M, Pool J, Shabanowitz J, Pettenati MJ, Eisenlohr LC, Hunt DF, Goulmy E, Engelhard VH. The HA-2 minor histocompatibility antigen is derived from a diallelic gene encoding a novel human class I myosin protein. Journal of Immunology (Baltimore, Md. : 1950). 167: 3223-30. PMID 11544309  0.96
2001 Luckey CJ, Marto JA, Partridge M, Hall E, White FM, Lippolis JD, Shabanowitz J, Hunt DF, Engelhard VH. Differences in the expression of human class I MHC alleles and their associated peptides in the presence of proteasome inhibitors. Journal of Immunology (Baltimore, Md. : 1950). 167: 1212-21. PMID 11466336  0.96
2001 Mosse CA, Hsu W, Engelhard VH. Tyrosinase degradation via two pathways during reverse translocation to the cytosol Biochemical and Biophysical Research Communications. 285: 313-319. PMID 11444844 DOI: 10.1006/bbrc.2001.5153  0.96
2001 Yamshchikov GV, Barnd DL, Eastham S, Galavotti H, Patterson JW, Deacon DH, Teates D, Neese P, Grosh WW, Petroni G, Engelhard VH, Slingluff CL. Evaluation of peptide vaccine immunogenicity in draining lymph nodes and peripheral blood of melanoma patients International Journal of Cancer. 92: 703-711. PMID 11340576 DOI: 10.1002/1097-0215(20010601)92:5<703::AID-IJC1250>3.0.CO;2-5  0.96
2001 Arichi T, Saito T, Major ME, Belyakov IM, Shirai M, Engelhard VH, Feinstone SM, Berzofsky JA. Retraction Proceedings of the National Academy of Sciences of the United States of America. 98: 5943. PMID 11331781  0.96
2001 Nepom GT, Lippolis JD, White FM, Masewicz S, Marto JA, Herman A, Luckey CJ, Falk B, Shabanowitz J, Hunt DF, Engelhard VH, Nepom BS. Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65). Proceedings of the National Academy of Sciences of the United States of America. 98: 1763-8. PMID 11172025 DOI: 10.1073/pnas.98.4.1763  0.96
2001 Akatsuka Y, Warren EH, Brickner AG, Engelhard VH, Riddell SR. Determination of intronic sequences adjacent to an exon using polymerase chain reaction and genomic DNA library constructed by TA cloning Analytical Biochemistry. 289: 289-292. PMID 11161324 DOI: 10.1006/abio.2000.4897  0.96
2001 Brickner AG, Warren EH, Caldwell JA, Akatsuka Y, Golovina TN, Zarling AL, Shabanowitz J, Eisenlohr LC, Hunt DF, Engelhard VH, Riddell SR. The immunogenicity of a new human minor histocompatibility antigen results from differential antigen processing. The Journal of Experimental Medicine. 193: 195-206. PMID 11148223 DOI: 10.1084/jem.193.2.195  0.96
2000 Zarling AL, Ficarro SB, White FM, Shabanowitz J, Hunt DF, Engelhard VH. Phosphorylated peptides are naturally processed and presented by major histocompatibility complex class I molecules in vivo. The Journal of Experimental Medicine. 192: 1755-62. PMID 11120772 DOI: 10.1084/jem.192.12.1755  0.96
2000 Lippolis JD, Denis-Mize KS, Brinckerhoff LH, Slingluff CL, Galloway DR, Engelhard VH. Pseudomonas exotoxin-mediated delivery of exogenous antigens to MHC class I and class II processing pathways Cellular Immunology. 203: 75-83. PMID 11006005 DOI: 10.1006/cimm.2000.1685  0.96
2000 Engelhard VH, Bullock TN, Colella TA, Mullins DW. Direct identification of human tumor-associated peptide antigens and a preclinical model to evaluate their use. Cancer Journal (Sudbury, Mass.). 6: S272-80. PMID 10874498  0.96
2000 Crotzer VL, Christian RE, Brooks JM, Shabanowitz J, Settlage RE, Marto JA, White FM, Rickinson AB, Hunt DF, Engelhard VH. Immunodominance among EBV-derived epitopes restricted by HLA-B27 does not correlate with epitope abundance in EBV-transformed B-lymphoblastoid cell lines. Journal of Immunology (Baltimore, Md. : 1950). 164: 6120-9. PMID 10843661  0.96
2000 Slingluff CL, Colella TA, Thompson L, Graham DD, Skipper JC, Caldwell J, Brinckerhoff L, Kittlesen DJ, Deacon DH, Oei C, Harthun NL, Huczko EL, Hunt DF, Darrow TL, Engelhard VH. Melanomas with concordant loss of multiple melanocytic differentiation proteins: immune escape that may be overcome by targeting unique or undefined antigens. Cancer Immunology, Immunotherapy : Cii. 48: 661-72. PMID 10752474  0.96
2000 Colella TA, Bullock TN, Russell LB, Mullins DW, Overwijk WW, Luckey CJ, Pierce RA, Restifo NP, Engelhard VH. Self-tolerance to the murine homologue of a tyrosinase-derived melanoma antigen: implications for tumor immunotherapy. The Journal of Experimental Medicine. 191: 1221-32. PMID 10748239 DOI: 10.1084/jem.191.7.1221  0.96
2000 Bullock TN, Colella TA, Engelhard VH. The density of peptides displayed by dendritic cells affects immune responses to human tyrosinase and gp100 in HLA-A2 transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 164: 2354-61. PMID 10679070  0.96
2000 Arichi T, Saito T, Major ME, Belyakov IM, Shirai M, Engelhard VH, Feinstone SM, Berzofsky JA. Prophylactic DNA vaccine for hepatitis C virus (HCV) infection: HCV- specific cytotoxic T lymphocyte induction and protection from HCV-recombinant vaccinia infection in an HLA-A2.1 transgenic mouse model Proceedings of the National Academy of Sciences of the United States of America. 97: 297-302. PMID 10618412 DOI: 10.1073/pnas.97.1.297  0.96
2000 Akatsuka Y, Warren EH, Brickner AG, Lin MT, Gooly T, Martin PJ, Hansen JA, Engelhard VH, Riddell SR. Effect of disparity in the newly identified minor histocompatibility antigen SKH13 on the development of graft-versus-host disease after marrow transplantation from an HLA-identical sibling Blood. 96.  0.96
1999 Pierce RA, Field ED, den Haan JM, Caldwell JA, White FM, Marto JA, Wang W, Frost LM, Blokland E, Reinhardus C, Shabanowitz J, Hunt DF, Goulmy E, Engelhard VH. Cutting edge: the HLA-A*0101-restricted HY minor histocompatibility antigen originates from DFFRY and contains a cysteinylated cysteine residue as identified by a novel mass spectrometric technique. Journal of Immunology (Baltimore, Md. : 1950). 163: 6360-4. PMID 10586024  0.96
1999 Brinckerhoff LH, Kalashnikov VV, Thompson LW, Yamshchikov GV, Pierce RA, Galavotti HS, Engelhard VH, Slingluff CL. Terminal modifications inhibit proteolytic degradation of an immunogenic MART-127-35 peptide: Implications for peptide vaccines International Journal of Cancer. 83: 326-334. PMID 10495424 DOI: 10.1002/(SICI)1097-0215(19991029)83:3<326::AID-IJC7>3.0.CO;2-X  0.96
1999 Skipper JC, Gulden PH, Hendrickson RC, Harthun N, Caldwell JA, Shabanowitz J, Engelhard VH, Hunt DF, Slingluff CL. Mass-spectrometric evaluation of HLA-A*0201-associated peptides identifies dominant naturally processed forms of CTL epitopes from MART-1 and gp100. International Journal of Cancer. Journal International Du Cancer. 82: 669-77. PMID 10417764 DOI: 10.1002/(SICI)1097-0215(19990827)82:5<669::AID-IJC9>3.0.CO;2-#  0.96
1998 Hogan KT, Eisinger DP, Cupp SB, Lekstrom KJ, Deacon DD, Shabanowitz J, Hunt DF, Engelhard VH, Slingluff CL, Ross MM. The peptide recognized by HLA-A68.2-restricted, squamous cell carcinoma of the lung-specific cytotoxic T lymphocytes is derived from a mutated elongation factor 2 gene. Cancer Research. 58: 5144-50. PMID 9823325  0.96
1998 Sarobe P, Pendleton CD, Akatsuka T, Lau D, Engelhard VH, Feinstone SM, Berzofsky JA. Enhanced in vitro potency and in vivo immunogenicity of a CTL epitope from hepatitis C virus core protein following amino acid replacement at secondary HLA-A2.1 binding positions Journal of Clinical Investigation. 102: 1239-1248. PMID 9739058  0.96
1998 Luckey CJ, King GM, Marto JA, Venketeswaran S, Maier BF, Crotzer VL, Colella TA, Shabanowitz J, Hunt DF, Engelhard VH. Proteasomes can either generate or destroy MHC class I epitopes: evidence for nonproteasomal epitope generation in the cytosol. Journal of Immunology (Baltimore, Md. : 1950). 161: 112-21. PMID 9647214  0.96
1998 Wang W, Man S, Gulden PH, Hunt DF, Engelhard VH. Class I-restricted alloreactive cytotoxic T lymphocytes recognize a complex array of specific MHC-associated peptides. Journal of Immunology (Baltimore, Md. : 1950). 160: 1091-7. PMID 9570521  0.96
1998 Kittlesen DJ, Thompson LW, Gulden PH, Skipper JC, Colella TA, Shabanowitz J, Hunt DF, Engelhard VH, Slingluff CL, Shabanowitz JA. Human melanoma patients recognize an HLA-A1-restricted CTL epitope from tyrosinase containing two cysteine residues: implications for tumor vaccine development. Journal of Immunology (Baltimore, Md. : 1950). 160: 2099-106. PMID 9498746  0.96
1998 den Haan JM, Meadows LM, Wang W, Pool J, Blokland E, Bishop TL, Reinhardus C, Shabanowitz J, Offringa R, Hunt DF, Engelhard VH, Goulmy E. The minor histocompatibility antigen HA-1: a diallelic gene with a single amino acid polymorphism. Science (New York, N.Y.). 279: 1054-7. PMID 9461441 DOI: 10.1126/science.279.5353.1054  0.96
1998 Mosse CA, Meadows L, Luckey CJ, Kittlesen DJ, Huczko EL, Slingluff CL, Shabanowitz J, Hunt DF, Engelhard VH. The class I antigen-processing pathway for the membrane protein tyrosinase involves translation in the endoplasmic reticulum and processing in the cytosol. The Journal of Experimental Medicine. 187: 37-48. PMID 9419209 DOI: 10.1084/jem.187.1.37  0.96
1997 Genestier L, Paillot R, Bonnefoy-Berard N, Meffre G, Flacher M, Fèvre D, Liu YJ, Bouteiller PL, Waldmann H, Engelhard VH, Banchereau J, Revillard JP. Fas-independent apoptosis of activated T cells induced by antibodies to the HLA class I α1 domain Blood. 90: 3629-3639. PMID 9345047  0.96
1997 Williams NS, Engelhard VH. Perforin-dependent cytotoxic activity and lymphokine secretion by CD4+ T cells are regulated by CD8+ T cells Journal of Immunology. 159: 2091-2099. PMID 9278294  0.96
1997 Smith KD, Huczko E, Engelhard VH, Li YY, Lutz CT. Alloreactive cytotoxic T lymphocytes focus on specific major histocompatibility complex-bound peptides. Transplantation. 64: 351-9. PMID 9256200 DOI: 10.1097/00007890-199707270-00030  0.96
1997 Wang W, Gulden PH, Pierce RA, Shabanowitz J, Man ST, Hunt DF, Engelhard VH, Shabanowitz JA. A naturally processed peptide presented by HLA-A*0201 is expressed at low abundance and recognized by an alloreactive CD8+ cytotoxic T cell with apparent high affinity. Journal of Immunology (Baltimore, Md. : 1950). 158: 5797-804. PMID 9190931  0.96
1997 Loftus DJ, Chen Y, Covell DG, Engelhard VH, Appella E. Differential Contact of Disparate Class I/Peptide Complexes as the Basis for Epitope Cross-Recognition by a Single T Cell Receptor Journal of Immunology. 158: 3651-3658. PMID 9103427  0.96
1997 Meadows L, Wang W, den Haan JM, Blokland E, Reinhardus C, Drijfhout JW, Shabanowitz J, Pierce R, Agulnik AI, Bishop CE, Hunt DF, Goulmy E, Engelhard VH. The HLA-A*0201-restricted H-Y antigen contains a posttranslationally modified cysteine that significantly affects T cell recognition. Immunity. 6: 273-81. PMID 9075928 DOI: 10.1016/S1074-7613(00)80330-1  0.96
1997 Dubey P, Hendrickson RC, Meredith SC, Siegel CT, Shabanowitz J, Skipper JC, Engelhard VH, Hunt DF, Schreiber H. The immunodominant antigen of an ultraviolet-induced regressor tumor is generated by a somatic point mutation in the DEAD box helicase p68. The Journal of Experimental Medicine. 185: 695-705. PMID 9034148 DOI: 10.1084/jem.185.4.695  0.96
1996 Skipper JC, Kittlesen DJ, Hendrickson RC, Deacon DD, Harthun NL, Wagner SN, Hunt DF, Engelhard VH, Slingluff CL. Shared epitopes for HLA-A3-restricted melanoma-reactive human CTL include a naturally processed epitope from Pmel-17/gp100. Journal of Immunology (Baltimore, Md. : 1950). 157: 5027-33. PMID 8943411  0.96
1996 den Haan JM, Bontrop RE, Pool J, Sherman N, Blokland E, Engelhard VH, Hunt DF, Goulmy E. Conservation of minor histocompatibility antigens between human and non-human primates. European Journal of Immunology. 26: 2680-5. PMID 8921955 DOI: 10.1002/eji.1830261120  0.96
1996 Engelhard VH. Direct identification of tumor-associated peptide antigens Springer Seminars in Immunopathology. 18: 171-183. PMID 8908698 DOI: 10.1007/BF00820664  0.96
1996 Schumacher IK, Newberg MH, Jackson JD, Hammel JM, Rubocki RJ, Engelhard VH, Fox IJ. Use of gene therapy to suppress the antigen-specific immune responses in mice to an HLA antigen. Transplantation. 62: 831-6. PMID 8824485  0.96
1996 Smith KD, Mace BE, Valenzuela A, Vigna JL, McCutcheon JA, Barbosa JA, Huczko E, Engelhard VH, Lutz CT. Probing HLA-B7 conformational shifts induced by peptide-binding groove mutations and bound peptide with anti-HLA monoclonal antibodies. Journal of Immunology (Baltimore, Md. : 1950). 157: 2470-8. PMID 8805647  0.96
1996 Huang AY, Gulden PH, Woods AS, Thomas MC, Tong CD, Wang W, Engelhard VH, Pasternack G, Cotter R, Hunt D, Pardoll DM, Jaffee EM. The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product. Proceedings of the National Academy of Sciences of the United States of America. 93: 9730-5. PMID 8790399 DOI: 10.1073/pnas.93.18.9730  0.96
1996 Newberg MH, Smith DH, Haertel SB, Vining DR, Lacy E, Engelhard VH. Importance of MHC class 1 alpha2 and alpha3 domains in the recognition of self and non-self MHC molecules. Journal of Immunology (Baltimore, Md. : 1950). 156: 2473-80. PMID 8786307  0.96
1996 Gulden PH, Fischer P, Sherman NE, Wang W, Engelhard VH, Shabanowitz J, Hunt DF, Pamer EG. A Listeria monocytogenes pentapeptide is presented to cytolytic T lymphocytes by the H2-M3 MHC class Ib molecule. Immunity. 5: 73-9. PMID 8758896 DOI: 10.1016/S1074-7613(00)80311-8  0.96
1996 Skipper JC, Hendrickson RC, Gulden PH, Brichard V, Van Pel A, Chen Y, Shabanowitz J, Wolfel T, Slingluff CL, Boon T, Hunt DF, Engelhard VH. An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins. The Journal of Experimental Medicine. 183: 527-34. PMID 8627164 DOI: 10.1084/jem.183.2.527  0.96
1996 Williams NS, Engelhard VH. Identification of a population of CD4+ CTL that utilizes a perforin- rather than a Fas ligand-dependent cytotoxic mechanism Journal of Immunology. 156: 153-159. PMID 8598456  0.96
1996 Engelhard VH. A tyrosinase epitope is processed after translation into the endoplasmic reticulum Faseb Journal. 10.  0.96
1996 Williams NS, Engelhard VH. Regulation of the development of perforin-dependent cytotoxicity in CD4+ T cells by CD8+ T cells Faseb Journal. 10.  0.96
1996 Huczko EL, Rumpel CA, Chen Y, Engelhard VH. Effect of peptide MHC interaction on peptide priming of HLA-A2 restricted responses in transgenic mice Faseb Journal. 10.  0.96
1996 Wang W, Gulden PE, Pierce RA, Hunt DF, Engelhard VH. A naturally processed peptide presented by HLA-A2.1 is recognized by an alloreactive CD8+ cytotoxic T cell with high affinity Faseb Journal. 10.  0.96
1995 Wang W, Meadows LR, den Haan JM, Sherman NE, Chen Y, Blokland E, Shabanowitz J, Agulnik AI, Hendrickson RC, Bishop CE. Human H-Y: a male-specific histocompatibility antigen derived from the SMCY protein. Science (New York, N.Y.). 269: 1588-90. PMID 7667640  0.96
1995 Man S, Newberg MH, Crotzer VL, Luckey CJ, Williams NS, Chen Y, Huczko EL, Ridge JP, Engelhard VH. Definition of a human T cell epitope from influenza A non-structural protein 1 using HLA-A2.1 transgenic mice. International Immunology. 7: 597-605. PMID 7547687  0.96
1995 Den Haan JMM, Sherman NE, Blokland E, Huczko E, Koning F, Drijfhout JW, Skipper J, Shabanowitz J, Hunt DF, Engelhard VH, Goulmy E. Identification of a graft versus host disease-associated human minor histocompatibility antigen Science. 268: 1476-1480. PMID 7539551  0.96
1995 Shirai M, Arichi T, Nishioka M, Nomura T, Ikeda K, Kawanishi K, Engelhard VH, Feinstone SM, Berzofsky JA. CTL responses of HLA-A2.1-transgenic mice specific for hepatitis C viral peptides predict epitopes for CTL of humans carrying HLA-A2.1 Journal of Immunology. 154: 2733-2742. PMID 7533182  0.96
1995 Sidney J, del Guercio MF, Southwood S, Engelhard VH, Appella E, Rammensee HG, Falk K, Rötzschke O, Takiguchi M, Kubo RT. Several HLA alleles share overlapping peptide specificities. Journal of Immunology (Baltimore, Md. : 1950). 154: 247-59. PMID 7527812  0.96
1994 Beier DC, Cox JH, Vining DR, Cresswell P, Engelhard VH. Association of human class I MHC alleles with the adenovirus E3/19K protein Journal of Immunology. 152: 3862-3872. PMID 8144956  0.96
1994 Chen Y, Sidney J, Southwood S, Cox AL, Sakaguchi K, Henderson RA, Appella E, Hunt DF, Sette A, Engelhard VH. Naturally processed peptides longer than nine amino acid residues bind to the class I MHC molecule HLA-A2.1 with high affinity and in different conformations Journal of Immunology. 152: 2874-2881. PMID 8144888  0.96
1994 Engelhard VH. How cells process antigens Scientific American. 271: 54-61. PMID 8066431  0.96
1994 Man S, Ridge JP, Engelhard VH. Diversity and dominance among TCR recognizing HLA-A2.1+ influenza matrix peptide in human MHC class I transgenic mice Journal of Immunology. 153: 4458-4467. PMID 7963521  0.96
1994 Smith DM, Bluestone JA, Jeyarajah DR, Newberg MH, Engelhard VH, Thistlethwaite JR, Woodle ES. Inhibition of T cell activation by a monoclonal antibody reactive against the α3 domain of human MHC class I molecules Journal of Immunology. 153: 1054-1067. PMID 7913109  0.96
1994 Slingluff CL, Hunt DF, Engelhard VH. Direct analysis of tumor-associated peptide antigens Current Opinion in Immunology. 6: 733-740. PMID 7530012 DOI: 10.1016/0952-7915(94)90077-9  0.96
1994 Engelhard VH. Structure of peptides associated with class I and class II MHC molecules Annual Review of Immunology. 12: 181-207. PMID 7516668  0.96
1994 Engelhard VH. Structure of peptides associated with MHC class I molecules Current Opinion in Immunology. 6: 13-23. PMID 7513522 DOI: 10.1016/0952-7915(94)90028-0  0.96
1994 Cox AL, Skipper J, Chen Y, Henderson RA, Darrow TL, Shabanowitz J, Engelhard VH, Hunt DF, Slingluff CL. Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines Science. 264: 716-719. PMID 7513441  0.96
1994 Slingluff CL, Cox AL, Stover JM, Moore MM, Hunt DF, Engelhard VH. Cytotoxic T-Lymphocyte Response to Autologous Human Squamous Cell Cancer of the Lung: Epitope Reconstitution with Peptides Extracted from HLA-äW68 Cancer Research. 54: 2731-2737. PMID 7513255  0.96
1993 Huczko EL, Bodnar WM, Benjamin D, Sakaguchi K, Zhu NZ, Shabanowitz J, Henderson RA, Appella E, Hunt DF, Engelhard VH. Characteristics of Endogenous Peptides Eluted from the Class I MHC Molecule HLA-B7 Determined by Mass Spectrometry and Computer Modeling Journal of Immunology. 151: 2572-2587. PMID 8360479  0.96
1993 Engelhard VH, Appella E, Benjamin DC, Bodnar WM, Cox AL, Chen Y, Henderson RA, Huczko EL, Michel H, Sakaguichi K, Shabanowitz J, Sevilir N, Slingluff CL, Hunt DF. Mass spectrometric analysis of peptides associated with the human class I MHC molecules HLA-A2.1 and HLA-B7 and identification of structural features that determine binding Chemical Immunology. 57: 39-62. PMID 8260089  0.96
1993 Henderson RA, Cox AL, Sakaguchi K, Appella E, Shabanowitz J, Hunt DF, Engelhard VH. Direct identification of an endogenous peptide recognized by multiple HLA-A2.1-specific cytotoxic T cells Proceedings of the National Academy of Sciences of the United States of America. 90: 10275-10279. PMID 7694286  0.96
1993 Slingluff CL, Cox AL, Henderson RA, Hunt DF, Engelhard VH. Recognition of Human Melanoma Cells by HLA-A2.1-Restricted Cytotoxic T Lymphocytes Is Mediated by at Least Six Shared Peptide Epitopes Journal of Immunology. 150: 2955-2963. PMID 7681084  0.96
1992 Newberg MH, Ridge JP, Vining DR, Salter RD, Engelhard VH. Species specificity in the interaction of CD8 with the α3 domain of MHC class I molecules Journal of Immunology. 149: 136-142. PMID 1607650  0.96
1992 Henderson RA, Michel H, Sakaguchi K, Shabanowitz J, Appella E, Hunt DF, Engelhard VH. HLA-A2.1-associated peptides from a mutant cell line: A second pathway of antigen presentation Science. 255: 1264-1266. PMID 1546329  0.96
1992 Hunt DF, Henderson RA, Shabanowitz J, Sakaguchi K, Michel H, Sevilir N, Cox AL, Appella E, Engelhard VH. Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry Science. 255: 1261-1263. PMID 1546328  0.96
1992 Barzaga-Gilbert E, Grass D, Lawrance SK, Peterson PA, Lacy E, Engelhard VH. Species specificity and augmentation of responses to class II major histocompatibility complex molecules in human CD4 transgenic mice. The Journal of Experimental Medicine. 175: 1707-15. PMID 1534116  0.96
1992 Crumpacker DB, Alexander J, Cresswell P, Engelhard VH. Role of endogenous peptides in murine allogeneic cytotoxic T cell responses assessed using transfectants of the antigen-processing mutant 174xCEM.T2 Journal of Immunology. 148: 3004-3011. PMID 1374446  0.96
1992 Man S, Salter RD, Engelhard VH. Role of endogenous peptide in human alloreactive cytotoxic T cell responses International Immunology. 4: 367-375. PMID 1373643 DOI: 10.1093/intimm/4.3.367  0.96
1992 Hunt DF, Shabanowitz J, Michel H, Cox AL, Dickinson T, Davis T, Bodnar W, Henderson RA, Sevilir N, Engelhard VH, Sakaguchi K, Appella E, Grey HM, Sette A. Sequence analysis of peptides presented to the immune system by class I and class II MHC molecules Journal of Protein Chemistry. 11: 377-378. DOI: 10.1007/BF01673734  0.96
1991 Haverstick DM, Engelhard VH, Gray LS. Three intracellular signals for cytotoxic T lymphocyte-mediated killing Independent roles for protein kinase C, Ca2+ influx, and Ca2+ release from internal stores Journal of Immunology. 146: 3306-3313. PMID 2026868  0.96
1991 Engelhard VH, Lacy E, Ridge JP. Influenza A-specific, HLA-A2.1-restricted cytotoxic T lymphocytes from HLA-A2.1 transgenic mice recognize fragments of the M1 protein. Journal of Immunology (Baltimore, Md. : 1950). 146: 1226-32. PMID 1704033  0.96
1990 Spits H, Paliard X, Engelhard VH, De Vries JE. Cytotoxic activity and lymphokine production of T cell receptor (TCR)-αβ+ and TCR-γδ+ cytotoxic T lymphocyte (CTL) clones recognizing HLA-A2 and HLA-A2 mutants: Recognition of TCR-γδ+ CTL clones is affected by mutations at positions 152 and 156 Journal of Immunology. 144: 4156-4162. PMID 2111341  0.96
1989 Gray LS, Huber KS, Gray MC, Hewlett EL, Engelhard VH. Pertussis toxin effects on T lymphocytes are mediated through CD3 and not by pertussis toxin catalyzed modification of a G protein Journal of Immunology. 142: 1631-1638. PMID 2521885  0.96
1989 Shimojo N, Cowan EP, Engelhard VH, Maloy WL, Coligan JE, Biddison WE. A single amino acid substitution in HLA-A2 can alter the selection of the cytotoxic T lymphocyte repertoire that responds to influenza virus matrix peptide 55-73 Journal of Immunology. 143: 558-564. PMID 2472444  0.96
1989 Hogan KT, Clayberger C, Bernhard EJ, Walk SF, Ridge JP, Parham P, Krensky AM, Engelhard VH. A panel of unique HLA-A2 mutant molecules define epitopes recognized by HLA-A2-specific antibodies and cytotoxic T lymphocytes Journal of Immunology. 142: 2097-2104. PMID 2466083  0.96
1989 Le AX, Bernhard EJ, Holterman MJ, Strub S, Parham P, Lacy E, Engelhard VH. Cytotoxic T cell responses in HLA-A2.1 transgenic mice. Recognition of HLA alloantigens and utilization of HLA-A2.1 as a restriction element. Journal of Immunology (Baltimore, Md. : 1950). 142: 1366-71. PMID 2464645  0.96
1988 Norment AM, Salter RD, Parham P, Engelhard VH, Littman DR. Cell-cell adhesion mediated by CD8 and MHC class I molecules Nature. 336: 79-81. PMID 3263576  0.96
1988 Engelhard VH, Gnarra JR, Sullivan J, Mandell GL, Gray LS. Early events in target-cell lysis by cytotoxic T cells Annals of the New York Academy of Sciences. 532: 303-313. PMID 3263073  0.96
1988 Bernhard EJ, Le AX, Barbosa JA, Lacy E, Engelhard VH. Cytotoxic T lymphocytes from HLA-A2 transgenic mice specific for HLA-A2 expressed on human cells. The Journal of Experimental Medicine. 168: 1157-62. PMID 3262704  0.96
1988 Gray LS, Gnarra JR, Sullivan JA, Mandell GL, Engelhard VH. Spatial and temporal characteristics of the increase in intracellular Ca2+ induced in cytotoxic T lymphocytes by cellular antigen. Journal of Immunology (Baltimore, Md. : 1950). 141: 2424-30. PMID 3262660  0.96
1988 Engelhard VH, Le AX, Holterman MJ. Species-specific structural differences in the alpha 1 + alpha 2 domains determine the frequency of murine cytotoxic T cell precursors stimulated by human and murine class I molecules. Journal of Immunology (Baltimore, Md. : 1950). 141: 1835-9. PMID 3262639  0.96
1988 Hogan KT, Shimojo N, Walk SF, Engelhard VH, Maloy WL, Coligan JE, Biddison WE. Mutations in the α2 helix of HLA-A2 affect presentation but do not inhibit binding of influenza virus matrix peptide Journal of Experimental Medicine. 168: 725-736. PMID 3261776  0.96
1988 Scott J, Benjamin DC, Herr JC, Engelhard VH. Sites of the defects leading to autoimmunity in the spontaneously diabetic BB rat Advances in Experimental Medicine and Biology. 246: 53-62. PMID 3074668  0.96
1988 Scott J, Engelhard VH, Benjamin DC. Prevention of diabetes in the BB rat by injection of major histocompatibility complex- (MHC-) compatible bone marrow cells Advances in Experimental Medicine and Biology. 246: 387-395. PMID 2977930  0.96
1988 Gray LS, Gnarra J, Hewlett EL, Engelhard VH. Increased intracellular cyclic adenosine monophosphate inhibits T lymphocyte-mediated cytolysis by two distinct mechanisms Journal of Experimental Medicine. 167: 1963-1968. PMID 2838563  0.96
1988 Hogan KT, Clayberger C, Le AXT, Walk SF, Ridge JP, Parham P, Krensky AM, Engelhard VH. Cytotoxic T lymphocyte-defined epitope differences between HLA-A2.1 and HLA-A2.2 map to two distinct regions of the molecule Journal of Immunology. 141: 4005-4011. PMID 2460555  0.96
1988 Hogan KT, Clayberger C, Bernhard EJ, Walk SF, Ridge JP, Parham P, Krensky AM, Engelhard VH. Identification by site-directed mutagenesis of amino acid residues contributing to serologic and CTL-defined epitope differences between HLA-A2.1 and HLA-A2.3 Journal of Immunology. 141: 2519-2525. PMID 2459215  0.96
1987 Gray LS, Gnarra JR, Engelhard VH. Demonstration of a calcium influx in cytolytic T lymphocytes in response to target cell binding Journal of Immunology. 138: 63-69. PMID 3491161  0.96
1987 Scott J, Engelhard VH, Benjamin DC. Bone marrow irradiation chimeras in the BB rat: evidence suggesting two defects leading to diabetes and lymphopoenia Diabetologia. 30: 774-781. PMID 3322903 DOI: 10.1007/BF00275743  0.96
1987 Bernhard EJ, Le AX, Yannelli JR, Holterman MJ, Hogan KT, Parham P, Engelhard VH. The ability of cytotoxic T cells to recognize HLA-A2.1 or HLA-B7 antigens expressed on murine cells correlates with their epitope specificity. Journal of Immunology (Baltimore, Md. : 1950). 139: 3614-21. PMID 2445816  0.96
1987 Gray LS, Gnarra JR, Russell JH, Engelhard VH. The role of K+ in the regulation of the increase in intracellular Ca2+ mediated by the T lymphocyte antigen receptor Cell. 50: 119-127. PMID 2439211 DOI: 10.1016/0092-8674(87)90668-4  0.96
1986 Yannelli JR, Sullivan JA, Mandell GL, Engelhard VH. Reorientation and fusion of cytotoxic T lymphocyte granules after interaction with target cells as determined by high resolution cinemicrography. Journal of Immunology (Baltimore, Md. : 1950). 136: 377-82. PMID 3510248  0.96
1986 Holterman MJ, Engelhard VH. HLA antigens expressed on murine cells are preferentially recognized by murine cytotoxic T cells in the context of the H-2 major histocompatibility complex. Proceedings of the National Academy of Sciences of the United States of America. 83: 9699-703. PMID 3491988  0.96
1986 Gnarra JR, Engelhard VH. Derivation of cytotoxic T cell lines that express T cell receptor but exhibit reversible loss of stable antigen binding Journal of Immunology. 137: 3057-3064. PMID 3490508  0.96
1986 Scott J, Engelhard VH, Curnow RT, Benjamin DC. Prevention of diabetes in BB rats. I. Evidence suggesting a requirement for mature T cells in bone marrow inoculum of neonatally injected rats Diabetes. 35: 1034-1040. PMID 2943618  0.96
1985 Engelhard VH, Yannelli JR, Evans GA, Walk SF, Holterman MJ. Construction of novel class I histocompatibility antigens by interspecies exon shuffling. Journal of Immunology (Baltimore, Md. : 1950). 134: 4218-25. PMID 2985705  0.96
1985 Yannelli JR, Moore LC, Engelhard VH. Multiple epitopes on human and murine cells expressing HLA-B7 as defined by specific murine cytotoxic T cell clones. Journal of Immunology (Baltimore, Md. : 1950). 135: 900-5. PMID 2409157  0.96
1984 Correa Freire MC, Powers GA, Engelhard VH. Introduction of HLA-A/B antigens into lymphoid cell membranes by cell-liposome fusion Journal of Immunology. 132: 69-75. PMID 6361126  0.96
1984 Engelhard VH, Powers GA, Moore LC, Holterman MJ, Correa-Freire MC. Cytotoxic T lymphocyte recognition of HLA-A/B antigens introduced into EL4 cells by cell-liposome fusion. Journal of Immunology (Baltimore, Md. : 1950). 132: 76-80. PMID 6197461  0.96
1984 Guerra JR, Engelhard VH. Characterization of non-cytotoxic cell lines derived from murine cytotoxic T lymphocytes Federation Proceedings. 43.  0.96
1983 Engelhard VH, Benjamin C. Xenogeneic cytotoxic T-cell clones recognize alloantigenic determinants on HLA-A2. Immunogenetics. 18: 461-73. PMID 6196283 DOI: 10.1007/BF00364388  0.96
1983 Herman A, Parham P, Weissman SM, Engelhard VH. Recognition by xenogeneic cytotoxic T lymphocytes of cells expressing HLA-A2 or HLA-B7 after DNA-mediated gene transfer Proceedings of the National Academy of Sciences of the United States of America. 80: 5056-5060. PMID 6192447  0.96
1982 Engelhard VH, Benjamin C. Isolation and characterization of monoclonal mouse cytotoxic T lymphocytes with specificity for HLA-A,B or -DR alloantigens. Journal of Immunology (Baltimore, Md. : 1950). 129: 2621-9. PMID 6982933  0.96
1980 Strominger JL, Engelhard VH, Guild BC, Kostyk TG, Lancet D, Lopez de Castro JA, Orr HT, Parham P, Ploegh HL, Pober JS. Complete primary structure of human histocompatibility antigen HLA-B7: evolutionary and functional implications. Current Topics in Developmental Biology. 14: 97-113. PMID 7460613 DOI: 10.1016/S0070-2153(08)60190-8  0.96
1980 Engelhard VH, Kaufman JF, Strominger JL, Burakoff SJ. Specificity of mouse cytotoxic T lymphocytes stimulated with either HLA-A and B or HLA-DR antigens reconstituted into phospholipid vesicles Journal of Experimental Medicine. 152: 54-64. PMID 6157770  0.96
1980 Burakoff SJ, Engelhard VH, Kaufman J, Strominger JL. Induction of secondary cytotoxic T lymphocytes by liposomes containing HLA-DR antigens [23] Nature. 283: 495-497. PMID 6153237 DOI: 10.1038/283495a0  0.96
1979 Westcott KR, Engelhard VH, Storm DR. Production of cyclic AMP from extracellular ATP by intact LM cells Bba - General Subjects. 583: 47-54. PMID 217448 DOI: 10.1016/0304-4165(79)90308-8  0.96
1978 Engelhard VH, Guild BC, Helenius A, Terhorst C, Strominger JL. Reconstitution of purified detergent-soluble HLA-A and HLA-B antigens into phospholipid vesicles Proceedings of the National Academy of Sciences of the United States of America. 75: 3230-3234. PMID 356051  0.96
1978 Engelhard VH, Strominger JL, Mescher M, Burakoff S. Induction of secondary cytotoxic T lymphocytes by purified HLA-A and HLA-B antigens reconstituted into phospholipid vesicles Proceedings of the National Academy of Sciences of the United States of America. 75: 5688-5691. PMID 310125  0.96
1976 Engelhard VH, Esko JD, Storm DR, Glaser M. Modification of adenylate cyclase activity in LM cells by manipulation of the membrane phospholipid composition in vivo Proceedings of the National Academy of Sciences of the United States of America. 73: 4482-4486. PMID 1069999  0.96
1976 Engelhard VH, Plut DA, Storm DR. Subcellular location of adenylate cyclase in rat cardiac muscle Bba - General Subjects. 451: 48-61. PMID 188459 DOI: 10.1016/0304-4165(76)90256-7  0.96
Show low-probability matches.