| Year |
Citation |
Score |
| 2023 |
LaRock DL, LaRock CN. Assessing Interleukin-1β Activation During Pyroptosis. Methods in Molecular Biology (Clifton, N.J.). 2641: 163-169. PMID 37074649 DOI: 10.1007/978-1-0716-3040-2_13 |
0.776 |
|
| 2023 |
Johnson AF, Sands JS, Trivedi KM, Russell R, LaRock DL, LaRock CN. Constitutive secretion of pro-IL-18 allows keratinocytes to initiate inflammation during bacterial infection. Plos Pathogens. 19: e1011321. PMID 37068092 DOI: 10.1371/journal.ppat.1011321 |
0.772 |
|
| 2023 |
Everett MJ, Davies DT, Leiris S, Sprynski N, Llanos A, Castandet JM, Lozano C, LaRock CN, LaRock DL, Corsica G, Docquier JD, Pallin TD, Cridland A, Blench T, Zalacain M, et al. Chemical Optimization of Selective LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models. Acs Infectious Diseases. PMID 36669138 DOI: 10.1021/acsinfecdis.2c00418 |
0.78 |
|
| 2022 |
LaRock DL, Johnson AF, Wilde S, Sands JS, Monteiro MP, LaRock CN. Group A Streptococcus induces GSDMA-dependent pyroptosis in keratinocytes. Nature. 605: 527-531. PMID 35545676 DOI: 10.1038/s41586-022-04717-x |
0.705 |
|
| 2021 |
Atashgah RB, Ghasemi A, Raoufi M, Abdollahifar MA, Zanganeh S, Nejadnik H, Abdollahi A, Sharifi S, Lea B, Cuerva M, Akbarzadeh M, Alvarez-Lorenzo C, Ostad SN, Theus AS, LaRock DL, et al. Restoring Endogenous Repair Mechanisms to Heal Chronic Wounds with a Multifunctional Wound Dressing. Molecular Pharmaceutics. PMID 34279974 DOI: 10.1021/acs.molpharmaceut.1c00400 |
0.641 |
|
| 2020 |
Sun J, LaRock DL, Skowronski EA, Kimmey JM, Olson J, Jiang Z, O'Donoghue AJ, Nizet V, LaRock CN. The Pseudomonas aeruginosa protease LasB directly activates IL-1β. Ebiomedicine. 60: 102984. PMID 32979835 DOI: 10.1016/j.ebiom.2020.102984 |
0.635 |
|
| 2020 |
LaRock DL, Russell R, Johnson AF, Wilde S, LaRock CN. Group A Streptococcus Infection of the Nasopharynx Requires Proinflammatory Signaling Through the Interleukin-1 Receptor. Infection and Immunity. PMID 32719155 DOI: 10.1128/Iai.00356-20 |
0.798 |
|
| 2019 |
LaRock DL, Sands JS, Ettouati E, Richard M, Bushway PJ, Adler ED, Nizet V, LaRock CN. Inflammasome inhibition blocks cardiac glycoside cell toxicity. The Journal of Biological Chemistry. PMID 31300552 DOI: 10.1074/Jbc.Ra119.008330 |
0.731 |
|
| 2017 |
Munguia J, LaRock DL, Tsunemoto H, Olson J, Cornax I, Pogliano J, Nizet V. The Mla pathway is critical for Pseudomonas aeruginosa resistance to outer membrane permeabilization and host innate immune clearance. Journal of Molecular Medicine (Berlin, Germany). PMID 28844103 DOI: 10.1007/S00109-017-1579-4 |
0.73 |
|
| 2016 |
LaRock CN, Todd J, LaRock DL, Olson J, O'Donoghue AJ, Robertson AAB, Cooper MA, Hoffman HM, Nizet V. IL-1β is an innate immune sensor of microbial proteolysis. Science Immunology. 1: eaah3539. PMID 28783696 DOI: 10.1126/sciimmunol.aah3539 |
0.796 |
|
| 2016 |
LaRock CN, Todd J, LaRock DL, Olson J, O'Donoghue AJ, Robertson AA, Cooper MA, Hoffman HM, Nizet V. IL-1β is an innate immune sensor of microbial proteolysis. Science Immunology. 1. PMID 28331908 DOI: 10.1126/Sciimmunol.Aah3539 |
0.798 |
|
| 2015 |
LaRock DL, Chaudhary A, Miller SI. Salmonellae interactions with host processes. Nature Reviews. Microbiology. 13: 191-205. PMID 25749450 DOI: 10.1038/Nrmicro3420 |
0.573 |
|
| 2012 |
Spinner JL, Jarrett CO, LaRock DL, Miller SI, Collins CM, Hinnebusch BJ. Yersinia pestis insecticidal-like toxin complex (Tc) family proteins: characterization of expression, subcellular localization, and potential role in infection of the flea vector. Bmc Microbiology. 12: 296. PMID 23249165 DOI: 10.1186/1471-2180-12-296 |
0.539 |
|
| 2012 |
LaRock DL, Brzovic PS, Levin I, Blanc MP, Miller SI. A Salmonella typhimurium-translocated glycerophospholipid:cholesterol acyltransferase promotes virulence by binding to the RhoA protein switch regions. The Journal of Biological Chemistry. 287: 29654-63. PMID 22740689 DOI: 10.1074/Jbc.M112.363598 |
0.508 |
|
| 2009 |
Christen M, Coye LH, Hontz JS, LaRock DL, Pfuetzner RA, Megha, Miller SI. Activation of a bacterial virulence protein by the GTPase RhoA. Science Signaling. 2: ra71. PMID 19887681 DOI: 10.1126/Scisignal.2000430 |
0.535 |
|
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