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Jason W. Upton, Ph.D. - Publications

Affiliations: 
2006 Washington University, Saint Louis, St. Louis, MO 
Area:
Virology Biology, Cell Biology
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Yadav SK, Gawargi FI, Hasan MH, Tandon R, Upton JW, Mishra PK. Differential effects of CMV infection on the viability of cardiac cells. Cell Death Discovery. 9: 111. PMID 37012234 DOI: 10.1038/s41420-023-01408-y  0.34
2021 Koehler H, Cotsmire S, Zhang T, Balachandran S, Upton JW, Langland J, Kalman D, Jacobs BL, Mocarski ES. Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis. Cell Host & Microbe. PMID 34192517 DOI: 10.1016/j.chom.2021.05.009  0.352
2020 Lane RK, Guo H, Fisher AD, Diep J, Lai Z, Chen Y, Upton JW, Carette J, Mocarski ES, Kaiser WJ. Necroptosis-based CRISPR knockout screen reveals Neuropilin-1 as a critical host factor for early stages of murine cytomegalovirus infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 32747526 DOI: 10.1073/Pnas.1921315117  0.368
2020 Zhang T, Yin C, Boyd DF, Quarato G, Ingram JP, Shubina M, Ragan KB, Ishizuka T, Crawford JC, Tummers B, Rodriguez DA, Xue J, Peri S, Kaiser WJ, López CB, ... ... Upton JW, et al. Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis. Cell. 180: 1115-1129.e13. PMID 32200799 DOI: 10.1016/J.Cell.2020.02.050  0.528
2019 Upton JW, Kaiser WJ, Mocarski ES. DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA. Cell Host & Microbe. 26: 564. PMID 31600504 DOI: 10.1016/j.chom.2019.09.004  0.305
2018 Guo H, Gilley RP, Fisher A, Lane R, Landsteiner VJ, Ragan KB, Dovey CM, Carette JE, Upton JW, Mocarski ES, Kaiser WJ. Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1. Cell Death & Disease. 9: 816. PMID 30050136 DOI: 10.1038/S41419-018-0868-3  0.561
2018 Gopal S, Perez E, Xia AY, Knowlton JJ, Cerqueira F, Dermody TS, Upton JW. Murine cytomegalovirus M72 promotes acute virus replication in vivo and is a substrate of the TRiC/CCT complex. Virology. 522: 92-105. PMID 30029015 DOI: 10.1016/J.Virol.2018.07.008  0.343
2017 Koehler H, Cotsmire S, Langland J, Kibler KV, Kalman D, Upton JW, Mocarski ES, Jacobs BL. Inhibition of DAI-dependent necroptosis by the Z-DNA binding domain of the vaccinia virus innate immune evasion protein, E3. Proceedings of the National Academy of Sciences of the United States of America. 114: 11506-11511. PMID 29073079 DOI: 10.1073/Pnas.1700999114  0.474
2017 Maelfait J, Liverpool L, Bridgeman A, Ragan KB, Upton JW, Rehwinkel J. Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis. The Embo Journal. PMID 28716805 DOI: 10.15252/Embj.201796476  0.399
2017 Sridharan H, Ragan KB, Guo H, Gilley RP, Landsteiner VJ, Kaiser WJ, Upton JW. Murine cytomegalovirus IE3-dependent transcription is required for DAI/ZBP1-mediated necroptosis. Embo Reports. PMID 28607035 DOI: 10.15252/Embr.201743947  0.459
2017 Ragan KB, Upton JW. Host response: Neurons loosen the gRIP of death. Nature Microbiology. 2: 17090. PMID 28530667 DOI: 10.1038/Nmicrobiol.2017.90  0.499
2017 Upton JW, Shubina M, Balachandran S. RIPK3-driven cell death during virus infections. Immunological Reviews. 277: 90-101. PMID 28462524 DOI: 10.1111/Imr.12539  0.556
2017 Upton JW, Kaiser WJ. DAI Another Way: Necroptotic Control of Viral Infection. Cell Host & Microbe. 21: 290-293. PMID 28279333 DOI: 10.1016/J.Chom.2017.01.016  0.499
2017 Hilterbrand AT, Boutz DR, Marcotte EM, Upton JW. Murine Cytomegalovirus Deubiquitinase Regulates Viral Chemokine Levels To Control Inflammation and Pathogenesis. Mbio. 8. PMID 28096485 DOI: 10.1128/Mbio.01864-16  0.462
2017 Berger AK, Hiller BE, Thete D, Snyder AJ, Perez E, Upton JW, Danthi P. Viral RNA at two stages of reovirus infection is required for the induction of necroptosis. Journal of Virology. PMID 28077640 DOI: 10.1128/Jvi.02404-16  0.465
2016 Thapa RJ, Ingram JP, Ragan KB, Nogusa S, Boyd DF, Benitez AA, Sridharan H, Kosoff R, Shubina M, Landsteiner VJ, Andrake M, Vogel P, Sigal LJ, tenOever BR, Thomas PG, ... Upton JW, et al. DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death. Cell Host & Microbe. PMID 27746097 DOI: 10.1016/J.Chom.2016.09.014  0.507
2016 Dick JE, Hilterbrand AT, Strawsine LM, Upton JW, Bard AJ. Enzymatically enhanced collisions on ultramicroelectrodes for specific and rapid detection of individual viruses. Proceedings of the National Academy of Sciences of the United States of America. PMID 27217569 DOI: 10.1073/Pnas.1605002113  0.315
2015 Sun C, Schattgen SA, Pisitkun P, Jorgensen JP, Hilterbrand AT, Wang LJ, West JA, Hansen K, Horan KA, Jakobsen MR, O'Hare P, Adler H, Sun R, Ploegh HL, Damania B, ... Upton JW, et al. Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection. Journal of Immunology (Baltimore, Md. : 1950). 194: 1819-31. PMID 25595793 DOI: 10.4049/Jimmunol.1402495  0.428
2014 Mandal P, Berger SB, Pillay S, Moriwaki K, Huang C, Guo H, Lich JD, Finger J, Kasparcova V, Votta B, Ouellette M, King BW, Wisnoski D, Lakdawala AS, DeMartino MP, ... ... Upton J, et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Molecular Cell. 56: 481-95. PMID 25459880 DOI: 10.1016/J.Molcel.2014.10.021  0.395
2014 Upton JW, Chan FK. Staying alive: cell death in antiviral immunity. Molecular Cell. 54: 273-80. PMID 24766891 DOI: 10.1016/J.Molcel.2014.01.027  0.508
2014 Sridharan H, Upton JW. Programmed necrosis in microbial pathogenesis. Trends in Microbiology. 22: 199-207. PMID 24565922 DOI: 10.1016/J.Tim.2014.01.005  0.439
2014 Mocarski ES, Kaiser WJ, Livingston-Rosanoff D, Upton JW, Daley-Bauer LP. True grit: Programmed necrosis in antiviral host defense, inflammation, and immunogenicity Journal of Immunology. 192: 2019-2026. PMID 24563506 DOI: 10.4049/Jimmunol.1302426  0.528
2014 Upton JW, Sridharan H. InFLUencing host survival: cIAP2 tips the scales. Cell Host & Microbe. 15: 3-5. PMID 24439892 DOI: 10.1016/J.Chom.2013.12.012  0.387
2013 Kaiser WJ, Sridharan H, Huang C, Mandal P, Upton JW, Gough PJ, Sehon CA, Marquis RW, Bertin J, Mocarski ES. Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL. The Journal of Biological Chemistry. 288: 31268-79. PMID 24019532 DOI: 10.1074/Jbc.M113.462341  0.406
2013 Kaiser WJ, Upton JW, Mocarski ES. Viral modulation of programmed necrosis. Current Opinion in Virology. 3: 296-306. PMID 23773332 DOI: 10.1016/J.Coviro.2013.05.019  0.465
2012 Upton JW, Kaiser WJ, Mocarski ES. DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA. Cell Host & Microbe. 11: 290-7. PMID 22423968 DOI: 10.1016/J.Chom.2012.01.016  0.544
2012 Mocarski ES, Upton JW, Kaiser WJ. Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways. Nature Reviews. Immunology. 12: 79-88. PMID 22193709 DOI: 10.1038/Nri3131  0.485
2011 Kaiser WJ, Upton JW, Long AB, Livingston-Rosanoff D, Daley-Bauer LP, Hakem R, Caspary T, Mocarski ES. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature. 471: 368-72. PMID 21368762 DOI: 10.1038/Nature09857  0.446
2010 Upton JW, Kaiser WJ, Mocarski ES. Virus inhibition of RIP3-dependent necrosis. Cell Host & Microbe. 7: 302-13. PMID 20413098 DOI: 10.1016/J.Chom.2010.03.006  0.581
2008 Kaiser WJ, Upton JW, Mocarski ES. Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors. Journal of Immunology (Baltimore, Md. : 1950). 181: 6427-34. PMID 18941233 DOI: 10.4049/Jimmunol.181.9.6427  0.369
2008 Upton JW, Kaiser WJ, Mocarski ES. Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1. The Journal of Biological Chemistry. 283: 16966-70. PMID 18442983 DOI: 10.1074/Jbc.C800051200  0.461
2006 Upton JW, Speck SH. Evidence for CDK-dependent and CDK-independent functions of the murine gammaherpesvirus 68 v-cyclin. Journal of Virology. 80: 11946-59. PMID 17005668 DOI: 10.1128/Jvi.01722-06  0.443
2006 Moser JM, Farrell ML, Krug LT, Upton JW, Speck SH. A gammaherpesvirus 68 gene 50 null mutant establishes long-term latency in the lung but fails to vaccinate against a wild-type virus challenge. Journal of Virology. 80: 1592-8. PMID 16415035 DOI: 10.1128/Jvi.80.3.1592-1598.2006  0.453
2005 Upton JW, van Dyk LF, Speck SH. Characterization of murine gammaherpesvirus 68 v-cyclin interactions with cellular cdks. Virology. 341: 271-83. PMID 16102793 DOI: 10.1016/J.Virol.2005.07.014  0.368
2005 Moser JM, Upton JW, Allen RD, Wilson CB, Speck SH. Role of B-cell proliferation in the establishment of gammaherpesvirus latency. Journal of Virology. 79: 9480-91. PMID 16014911 DOI: 10.1128/Jvi.79.15.9480-9491.2005  0.467
2005 Moser JM, Upton JW, Gray KS, Speck SH. Ex vivo stimulation of B cells latently infected with gammaherpesvirus 68 triggers reactivation from latency. Journal of Virology. 79: 5227-31. PMID 15795307 DOI: 10.1128/Jvi.79.8.5227-5231.2005  0.445
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